Clathrin adaptors link cargo to the clathrin coat. The clathrin adaptor Ent5 is also required for the maturation of clathrin coats at the trans-Golgi network or endosome, suggesting that it plays a ke...

Your role The Microscopy Specialist contributes to the delivery and continuous advancement of the EMBL Imaging Centre by providing specalist expertise in super-resolution cryo-light microscopy (Cryo-L...

The long-living rodent naked mole-rat has a distinct break in its 28S ribosomal RNA. Here, the authors present cryo-EM structures showing this cleavage is stabilized by surrounding ribosomal proteins,...

Applications are open for 2 PhD student places.  Closing date for applications is Thursday 26 June, 5pm. Interviews will be held on 9th July 2026. The Cheney Scholarship is a prestigious 4-year PhD pr...

COMMD proteins assemble into a heterodecameric ring in the Commander complex, which plays a role in endosomal membrane trafficking and signalling in eukaryotes. Here, Liu et al. identify COMMD-like pr...

AP3 generates clathrin-free carriers on endosomes by organizing via ARF1 dimers into elongated membrane-deforming arrays.

Ultrastructural studies by Bonnett and Newcomb in 1966 revealed the existence of coated vesicles budding from the plant cell plasma membrane. This review introduces this discovery and early questions...

A lab operating system and AI agent for structured molecular and structural biology workflows.

The discovery of membrane trafficking proteins in Asgard archaea—the closest archaeal relatives of eukaryotes—reveals the deep evolutionary roots of the eukaryotic endomembrane system. This review syn...

Lycas et al. develop a cryo-CLEM workflow to characterize the ultrastructure of dopaminergic varicosities. They resolve in situ structures of TRiC/CCT and

The research group Ubiquitin Signaling Specificity (Dr. Sonja Lorenz) invites applications for the position as PhD student or Postdoc (f/m/d) – Understanding and manipulating ubiquitin ligase specifi...

Endosomal GTPases, while often used as markers for specific endosomal organelles, functionalize the surface of endosomal compartments into biochemical…

The mitochondrial oxidative phosphorylation system powering most aerobic organisms is typically depicted as two spatially segregated machineries(1): electron transport chain complexes I-IV (ETC CI-CIV

A host lipid flips a viral protein’s shape to control membrane remodeling during virus replication.

Lennartz et al. introduce a correlative light and electron microscopy workflow, Lipid-CLEM, combining near-native lipid probes and on-section labelling via click chemistry. Lipid-CLEM quantitatively a...

Endosomes serve as crucial sorting centers that streamline the distribution of cell surface proteins. The early endosome receives traffic from both th…

Job Posting Title: Postdoctoral Fellow ---- Hiring Department: Molecular Biosciences ---- Position Open To: All Applicants ---- Weekly Scheduled Hours: 40 ---- FLSA Status: Exempt ---- Earliest Start ...