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Cutting-edge research, news, commentary, and visuals from the Science family of journals. www.science.org

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Science Magazine @science.org · 24/09/2026
Learning over an extended childhood has been fundamental to survival during human evolutionary history. Researchers show how Sumatran orangutans use their 8 years of dependency to master a broad diet, necessary for independent survival. Read more in this week’s issue: scim.ag/4xDjOfh
Learning over an extended childhood has been fundamental to survival during human evolutionary history. Researchers show how Sumatran orangutans use their 8 years of dependency to master a broad diet, necessary for independent survival. They find that infants have individual tendencies to engage in social and individual learning, which together determine diet profile breadth acquired by independence. The finding offers insights into the evolutionary roots of the complex learning mechanisms that characterize humans.

Photo: Suzi Eszterhas/Minden
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Science Magazine @science.org · 1h
NASA has selected a far-infrared space telescope to explore the faint, cool glow of gas and dust that fuel star formation and coalesce into planets. scim.ag/4z0OZ5m
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New space telescope will reopen astronomers’ view of the far-infrared
NASA’s $1.2 billion PRIMA will explore how galaxies evolve and how planets emerge from disks of gas and dust
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Science Magazine @science.org · 2h
A biochemical analysis in #ScienceSignaling examines how a family of enzymes called atypical protein kinase Cs can have opposing effects on the growth of tumor cells—answering a persistent question in the study of #cancer biology. scim.ag/4dCF2ms
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S1P mimics phosphorylation to mediate PDK1-independent activation of aPKC with an opposing downstream effect
A bioactive lipid activates aPKC like phosphorylation does but switches the effect of aPKC on apoptosis.
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Sar Crespi @boron110.bsky.social · 4h
Kicking infected cells out of the airway @science.org #ScienceAdvances "Airway epithelia clear rhinovirus infection via two waves of cell extrusion" www.science.org/doi/10.1126/...
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Daniel Krentzel @danielkrentzel.bsky.social · 5h
Our paper outlining a deep learning-based phenotypic screening method to discover new TB drugs is out in @science.org #ScienceAdvances 💊🦠 It's the result of a great collaboration between the labs of @chzimmer.bsky.social and @awehenkel.bsky.social at @pasteur.fr! 📃 www.science.org/doi/10.1126/...
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Deep learning extracts MoA-specific signatures from high-throughput images of chemically and genetically perturbed Corynebacteria
To address drug-resistant tuberculosis, the leading single-pathogen infectious killer, drugs with novel modes of action (MoAs) are urgently needed. Phenotypic screening of chemical libraries can ident...
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Science Magazine @science.org · 4h
Luciana Gatti, who studies carbon uptake in the Amazon, aims to join Brazil’s lower house in this week’s elections. scim.ag/4xLuQzr
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Fed up with Brazil’s politicians not listening, a climate scientist runs for office
Luciana Gatti, who studies carbon uptake in the Amazon, aims to join Brazil’s lower house in this week’s elections
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Science Magazine @science.org · 19h
Heart attacks and strokes triggered by electrical misfiring in the heart are among the biggest killers on the planet. In 2022, researchers created a “liquid wire” that, when injected into pig hearts, can guide the organs to a normal rhythm. Learn more on #WorldHeartDay: scim.ag/4iUYkai
Injectable electrodes could prevent deadly heart arrhythmias
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Science Magazine @science.org · 20h
A biochemical deep dive deciphers how the same enzyme has contrasting effects on cancer growth, researchers build a global map of how light remodels phosphorylation in the eye of the fruit fly, and more in the new issue of #ScienceSignaling. scim.ag/3VdwiwU
The image is a colored scanning electron micrograph of the ommatidia and setae in a Drosophila compound eye.

Credit: Dennis Kunkel Microscopy/Science Source
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Taylor Mitchell Brown @tmitchellbrown.bsky.social · 23h
New research finds the Suriname toad’s strange star-shaped fingertips are a kind of tactile eyeball that allow them to ‘see’ their prey. The toes detect subtle vibrations in the water and translate them into details about size and speed. #ToadToesTuesday 🧪🧪 New at @science.org
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These frogs ‘see’ prey with their star-shaped toes
Fingertips of Suriname toads are hypersensitive motion detectors, new study reveals
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Science Magazine @science.org · 22h
"Pricing El Niño is not the same as preventing its loss of life. Yet, many of those acting on its forecasts are using them to move money, not people, out of harm’s way," writes Justin S. Mankin in a new #ScienceEditorial. scim.ag/4huP0HI
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Science Magazine @science.org · 23h
A new #ScienceAdvances study uses fMRI and the Stable Diffusion image generator to reveal a brain network that encodes visual representations of autobiographical mental images. scim.ag/3V9AX2N
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Medial temporal default mode network selectively encodes autobiographical visual imagery
The human brain’s capacity to imagine visual scenes from memory is thought to rely on the medial temporal subsystem of the default mode network (MT-DMN), yet the neural codes supporting this ability r...
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Sar Crespi @boron110.bsky.social · 29/09/2026
Poison ivy's rashiness is likely due to our immune systems reacting to urushiol--a mixture of lipids transferred from the plant to our skin--not your typical protein trigger. Mitch Leslie explores these lesser known rxns this week @science.org www.science.org/content/arti...
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Little-known arm of immune system could be key to better vaccines, cancer therapies
The CD1 system responds to lipids, not proteins, driving reactions to bee stings, bacteria, and possibly poison ivy
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Sara Reardon @sarareardon.bsky.social · 29/09/2026
The first transgenic cuttlefish is here, and it is beautiful. Our story @science.org explores the challenges @tessamontague.bsky.social and others face when engineering cephalopods. #GMO-Cthulhu 🐙🧪 www.science.org/content/arti...
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Scientists engineered a glowing cuttlefish. Why was it so hard?
Breakthroughs in genetically altering cephalopods pave way for new studies of perception, brain evolution, and more
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Science Magazine @science.org · 29/09/2026
Exclusive: Cuttlefish that glow red under fluorescent light represent the first cephalopods engineered to contain a new gene. This breakthrough can pave the way for new studies of perception, brain evolution, and more. scim.ag/46VspiG
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Scientists engineered a glowing cuttlefish. Why was it so hard?
Breakthroughs in genetically altering cephalopods pave way for new studies of perception, brain evolution, and more
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Science Magazine @science.org · 29/09/2026
A new #ScienceImmunology study highlights a neutrophil subset that accumulates in the placenta and promote trophoblast invasion to support early human pregnancy. scim.ag/46D2a0f
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Fibrinoid-associated neutrophils promote invasive placentation and neutrophil reprogramming at the maternal-fetal interface
Neutrophils adopt a tissue-adapted state at the early maternal-fetal interface that supports trophoblast invasion.
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Paul Voosen @voosen.me · 28/09/2026
New Horizons is now *three days away* from shutting off its two heliophysics instruments, simply because NASA has not provided the $2M in funding it had promised to the mission last year or this year. There is no science basis for shutting these off. Our earlier coverage:
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NASA’s New Horizons mission may shut down two instruments over lack of funding
Decision risks “incalculable loss” of data from the edge of the Sun’s influence, scientists say
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Science Magazine @science.org · 29/09/2026
On 28 September, a jet-powered drone slammed into the headquarters of the National Academy of Sciences of Ukraine in Kyiv, killing at least two people and destroying a section of the historic building. scim.ag/3TsMg5M
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Russian drone kills at least two in Ukraine science academy attack
New underground labs are being built as war rages on
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Science Magazine @science.org · 28/09/2026
Last year, scientists developed an innovative way to vaccinate the bats against rabies—by making use of their extraordinary fondness of mutual grooming. #WorldRabiesDay scim.ag/4yeJbVW
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Vampire bats’ mutual grooming helps spread innovative rabies vaccine
A gel that bats lick off one another’s fur could help prevent rabies outbreaks in cattle, a growing problem in Latin America
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Science Magazine @science.org · 28/09/2026
"For a long time, I thought becoming a scientist meant learning how to appear certain, composed, and knowledgeable. But the people I came to admire have held on to their willingness to ask questions and to be excited by what they did not yet know." #ScienceWorkingLife scim.ag/4rsIztb
An illustration of a man taking off a mask that looks like his own face. The headline reads: I thought ‘I don’t know’ signaled scientific incompetence. Now, I know different
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Sar Crespi @boron110.bsky.social · 28/09/2026
I love a crossover hit -- Ancient Rome plus volcanology @science.org #ScienceAdvanvces www.science.org/doi/10.1126/...
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Pliny the Younger advances geochronology
The eruption of Vesuvius volcano witnessed by Pliny the Younger in 79 CE is dated by the argon-40/argon-39 (40Ar/39Ar) method to 1938 ± 13 years (SD) before measurement in 2025 CE. Achievement of 0.7%...
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Science Magazine @science.org · 28/09/2026
Dogs, like humans, may favor consonants over vowels when parsing continuous speech, according to a new Science study comparing brain activity in the two species. Learn more: scim.ag/4ryMGEo
(A) ITC values for humans and dogs, averaged over the three midline electrodes (humans: Fpz, FCz, and CPz; dogs: Fz, FCz, and Cz), and participants in the frequency spectrum between 0 and 9 Hz, including word frequency and its first three harmonics independent of syllable-level contributions (1.33, 2.67, 5.33, and 6.67 Hz), syllable frequency (4 Hz), and speech sound frequency (8 Hz). Comparable electrode placement between species is illustrated on schematic brains by the yellow dots at analogous cortical lobes, frontal (red), parietal (blue), temporal (orange), and occipital (green). (B) Estimated marginal means ± SE of word-level ITC for each condition in humans and dogs, derived from GLMMs.
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Science Magazine @science.org · 28/09/2026
A “lab-on-a-contact lens” measures concentrations of #serotonin in tear fluid in animals and in humans in a pilot trial—offering a flexible and noninvasive tool to quantify a key marker of stress responses and behaviors. @ScienceTM scim.ag/46YzkYe
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Science Magazine @science.org · 28/09/2026
CD1 proteins on so-called antigen-presenting cells display lipids from pathogens to T cells to drive protective immune responses, but they also trigger skin inflammation in response to some lipids. Learn more: scim.ag/47lWnMR
Illustration of an immune reaction to urushiol. The first panel shows an inflammatory rash on hands and forearms. An inset illustration shows a zoomed-in view of a T cell and an antigen-presenting cell making contact, while surrounded by smaller lipid molcules. Another inset zooms in on the contact between the cells, showing how a lipid fits into the CD1 protein on the antigen-presenting cell. A T cell receptor can be triggered by touching CD1 and the lipid it holds, but sometimes the lipid is hidden due to where it sits in the protein, so only CD1 makes contact.
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Science Magazine @science.org · 28/09/2026
A reconfigurable helical brace can stabilize a telerobotic catheter or endoscope without obstructing blood flow, enabling telerobotic needle interventions such as drug delivery and fluid aspiration within the lungs in preclinical models. Learn more in #ScienceRobotics: scim.ag/4dMK2ow
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Science Magazine @science.org · 28/09/2026
A new initiative promises an Amazon-wide, regularly updated picture of what’s happening to plant and animal populations as development threatens one of the most species-rich parts of the world. Learn more: scim.ag/4yZbIio
Project will harness technology to track Amazon biodiversity in real time
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Science Magazine @science.org · 27/09/2026
As the planet warms and forests burn, can we replant them with new trees that will thrive in the decades ahead? Learn more: scim.ag/3TPgT5p
Bar chart showing forest area burned in high-severity burns from 1984 to 2021. Each bar has a black dot with error bars, representing the estimated planting need and middle 50% of estimates. Since 2000, the average annual area burned in high-severity fires has increased fivefold, relative to 1984 to 1999.
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Science Magazine @science.org · 26/09/2026
Researchers suggest our ancient relatives intentionally crafted these 1.4-million-year-old spheres, perhaps for the sheer joy of creating symmetry. Learn more: scim.ag/4y6xFMt #ScienceMagArchives
Were these stone balls made by ancient human relatives trying to perfect the sphere?
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Science Magazine @science.org · 25/09/2026
A devastating and mysterious algal bloom that hit the coast of South Australia last year, killing more than 600 different kinds of marine life, inflicted such severe damage that a famed population of the giant Australian cuttlefish might not recover. Learn more: scim.ag/4rrVhbz
One of nature’s greatest marine wonders may be about to vanish
An algal bloom has almost wiped out a unique population of giant cuttlefish—and their stunning mating swarms
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Science Magazine @science.org · 25/09/2026
Acoustofluidic Cryo-EM is a new specimen preparation strategy that uses acoustic waves to enhance cryo-electron microscopy. Learn more in #ScienceAdvances: scim.ag/3Vuh4n7
Illustration of Acoustofluidic Cryo-EM (ACE), a specimen preparation strategy that uses acoustic waves to enhance cryo-electron microscopy. In developing ACE, Yang et al. integrated acoustofluidic manipulation into a conventional plunge-freezing workflow, preserving the structural integrity of samples while improving imaging quality. The sound waves eliminate contamination as no physical tools are needed, helping prevent damage when capturing images and ensuring a more uniform distribution of nanoparticles. ACE provides a method to improve specimen quality and imaging efficiency and expand structural studies of challenging biological systems.

Credit: Jun Huang, Ying Chen, and coauthors
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Katie Langin @klangin.bsky.social · 25/09/2026
"Should we start hedging our bets?" A rare feature story for @science.org written by me—about research near my home in Colorado examining how to plant forests that will thrive in a world with more extreme fires and a changing climate. www.science.org/content/arti...
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Science Magazine @science.org · 25/09/2026
Ancient viral warfare could be at the root of modern class 1 CRISPR bacterial defense systems. Learn more in a new #SciencePerspective: scim.ag/46rOANl
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A viral origin for RNA-guided immunity
Ancient viral warfare could be at the root of modern class 1 CRISPR bacterial defense systems
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Science Magazine @science.org · 25/09/2026
Japan’s 2025 bear crisis, which produced 232 casualties, has been widely attributed to rapid population growth, but a new #ScienceAdvances study shows that a compounding breakdown of the forest’s food supply drove the surge in bear attacks. scim.ag/46HG5xB
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Compound food failure on a deteriorated mast system drives Japan’s bear conflict crisis
Climate change is recognized as a key amplifier of human-wildlife conflict, yet the underlying mechanism remains poorly understood. Japan’s 2025 bear crisis, which produced 232 casualties, has been wi...
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Science Magazine @science.org · 25/09/2026
Can the new cutting-edge AI models feel pain? They at least behave as if they do, according to a recent study. The work, which has not been peer reviewed, has divided #AI researchers. scim.ag/4hHU6BA
Can an AI feel pain? It can at least act like it does
Study reignites debate over what, if anything, machines can feel
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Science Magazine @science.org · 25/09/2026
New results in #ScienceSignaling reveal that the T cell adaptor protein PAG supports the function of #TCell immune synapses by connecting with actin, suggesting that it could offer a target to improve #immunotherapy in patients that show poor responses. scim.ag/3V1ilCa
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PAG supports T cell immune synapse function by binding to actin
A plasma membrane adaptor protein supports cytotoxic T cell function by connecting with the actin network.
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Sar Crespi @boron110.bsky.social · 25/09/2026
Sumatran orangutans have a long, long childhood (8 yrs!) but there's a lot to learn. This week on the @science.org podcast, we hear about how social and individual learning interact to shape ecological competence in orangutans w/ Elah Feder & Revathe Thillaikumar www.science.org/content/podc...
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Science Magazine @science.org · 25/09/2026
Marine geologists have sampled and deployed sensors to the sea floor around Malta to learn what life would have been like on one of the island’s now-submerged land bridges. Learn more: scim.ag/46EFVqQ
Submerged land bridge may have helped people cross the Mediterranean
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Science Magazine @science.org · 24/09/2026
Doing research that's crossing over into entrepreneurship? The BioInnovation Institute & Science Prize for Innovation recognizes bold researchers who are asking fundamental questions at the intersection of the life sciences and entrepreneurship. Apply by 1 November 2026: bit.ly/4y1aLWN
The image features the text "BII Science Prize for Innovation" on a white background.
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Science Magazine @science.org · 24/09/2026
“Strengthening replication and reproducibility is not an expression of diminished confidence in science. It is an investment in science’s capacity to correct itself,” writes Jay Bhattacharya in a new #ScienceEditorial. scim.ag/3UZFXXT
"… discovery and independent verification are inseparable pillars of science." - Jay Bhattacharya, National Institutes of Health
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Science Magazine @science.org · 24/09/2026
A recent Science Translational Medicine Review synthesizes the translational pipeline of research decoding how tumors interact with both the central and peripheral nervous systems to fuel their growth. Learn more on #WorldCancerResearchDay: scim.ag/3V3HaNK
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Cancer neuroscience: Mechanisms to medicine
Bidirectional cross-talk between neural circuits and tumors drives cancer progression and can be therapeutically targeted through drug repurposing.
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Anya Hess @anya-hess.bsky.social · 24/09/2026
Very excited to announce our paper is out in Science Advances @science.org! Our reconstructions show Pacific Walker Circulation was stronger during the Little Ice Age, consistent with projections of weakening with future warming www.science.org/doi/10.1126/... @whoi.edu @rutgersupress.bsky.social
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A strong Pacific Walker Circulation during the Little Ice Age
Reconstructions of climate over the past millennium provide context for disentangling anthropogenic forcing from natural multidecadal variability. However, the strength of the east-west tropical Pacif...
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Ruichao Eric Liu @ruichaoliu.bsky.social · 24/09/2026
1/ Thrilled to share my dissertation work in the Coco Chu Lab at @tsinghuauniversity.bsky.social now published in @science.org. 👉🏻 www.science.org/doi/10.1126/...
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T Revathe @revathe.bsky.social · 24/09/2026
!! New in @science.org !! How do animals learn broad skills necessary for survival in the wild? Our latest study on wild Sumatran orangutans at Suaq provides answers. 1/11 www.science.org/doi/10.1126/...
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How 8 years of social and individual learning interact to shape ecological competence in orangutans
Cultural learning permeates human skill and knowledge acquisition. To understand its importance for nonhuman apes, we analyzed just under 7000 records of behavioral bouts of social and individual lear...
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Sar Crespi @boron110.bsky.social · 24/09/2026
Inside of AI swarms, chatbots are adapting language to meet their own ends while, making it harder for humans to understand their inner workings -- this week on the @science.org podcast w/ Tom Howarth www.science.org/content/podc...
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Mark Levin @levinchem.bsky.social · 24/09/2026
Now online @science.org! www.science.org/doi/10.1126/...
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Embracing triplet nitrenes for C-to-N replacement of complex bicyclic (hetero)aryl azides
Despite recent proof-of-concept advances, aromatic carbon-to-nitrogen replacement reactions remain substrate specific and exhibit an overreliance on harsh oxidation methods that preclude their deploym...
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Science Magazine @science.org · 24/09/2026
A CRISPR-based, nanodroplet test can distinguish 15 species of nontuberculous #mycobacteria in clinical samples in just 3.5 hours, avoiding the need for long culture times that have long limited assays for mycobacteria. #ScienceTranslationalMedicine scim.ag/4iGFeEF
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A rapid CRISPR-based nanodroplet assay enables direct clinical identification of mycobacteria species
A rapid CRISPR-based nanodroplet assay enables multiplex detection and subspecies-level identification of mycobacteria in clinical samples.
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Science Magazine @science.org · 24/09/2026
A new generation of radiotherapies promises a more targeted attack on cancer. Learn more on #WorldCancerResearchDay: scim.ag/3IwH8YW
An illustration shows how antibodies, peptides, and other molecules can be used to target the radioisotope to a specific type of cancer cell, which it kills by damaging its DNA. Alpha particle emitters affect a smaller number of cells (5 to 10 per particle) but do more damage, causing double-strand DNA breaks, whereas beta emitter particles affect a wider area (75 to 100 cells per particle) but cause only single-strand DNA breaks.
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Christie Wilcox @nerdychristie.bsky.social · 24/09/2026
Do AIs feel pain? They behave like they might—and will do terrible things to lessen the ache. Read about that and more of the best in @science.org and science in this edition of #ScienceAdviser: www.science.org/content/arti... 🧪🤖
red blurred computer keys
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Science Magazine @science.org · 24/09/2026
Thomas Jefferson’s genome has been sequenced to substantiate the idea that the president fathered children with Sally Hemings, a Black woman he enslaved. But one of Hemings’s descendants has criticized the work and withdrawn her participation in the study. Learn more: scim.ag/4iKdSxA
DNA analysis strengthens evidence that Thomas Jefferson fathered children with Sally Hemings
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Science Magazine @science.org · 23/09/2026
The Thirty Meter Telescope has turned down Spain’s €1 billion offer to build the observatory on the island of La Palma, according to a statement from the Astrophysics Institute of the Canaries. Learn more: scim.ag/4iJOqIs
Giant telescope project rejects La Palma as backup site
U.S.-led Thirty Meter Telescope declines €1 billion Spanish offer to build the observatory on the Canary Islands
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Science Magazine @science.org · 23/09/2026
Don't miss the new issue of #ScienceTranslationalMedicine! scim.ag/4iLeEu3
Shown is lung histology of neonatal mice born preterm (upper) or born to dams in which preterm birth was prevented with indomethacin plus ivermectin (lower).

Credit: Jennifer L. Herington Vanderbilt University Medical Center
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