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Jonathan Kaufman

@jggkaufman.bsky.social
495 followers 778 following 51 posts

Structural cell biology/membrane trafficking

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Jonathan Kaufman @jggkaufman.bsky.social · 29/09/2026
How did another AP1 structure where not all the ARF1 can be on the membrane get published?
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 20/09/2026
Shot/chaser
inpreparation.substack.com
AI Lab Achieves Perfect Automation Of Experiments No One Does Anymore
MOUNTAIN VIEW, CA — Researchers at DeepMind announced Tuesday a major breakthrough in laboratory automation, unveiling an AI system capable of performing, with 99.7% accuracy and zero human interventi...
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Science Magazine @science.org · 28/05/2026
Researchers have identified superparamagnetic macrophages in the livers of rock pigeons to be crucial for magnetic sensing. The finding uncovers an unexpected role for immune cells in sensory perception and may fundamentally change our understanding of animal navigation. scim.ag/4nTQ3nq
How animals sense Earth’s magnetic field is one of biology’s enduring mysteries. Researchers have now identified superparamagnetic macrophages in the livers of rock pigeons (Columba livia) to be crucial for magnetic sensing. The finding uncovers an unexpected role for immune cells in sensory perception and may fundamentally change our understanding of animal navigation.

Photo: Andreas Teichmann/laif/Redux
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Jonathan Kaufman @jggkaufman.bsky.social · 18/05/2026
It's finally out! Molecular architecture of mammalian AP3:ARF1 carriers - a mechanism for lysosomal membrane protein trafficking - from a combination of #biochemistry, #cryoET and #cellbiology 📝 Paper: www.science.org/doi/10.1126/... 🧵 Thread: subsequently #teamtomo #membranetrafficking
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Jonathan Kaufman @jggkaufman.bsky.social · 12/05/2026
Very impressive paper on the structural basis of Tubulin dimers assembly and disassembly.
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KaufmannLab @kaufmannlab.bsky.social · 24/04/2026
Happy to see the preprint of our VULCROM setup online! Thanks to our amazing collaborators we've managed to get some pretty cool cryo-CLEM images by combining cryo super-resolution and cryo-ET: doi.org/10.64898/202...
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bioRxiv Cell Biology @biorxiv-cellbio.bsky.social · 30/03/2026
Shape2Fate: a morphology-aware deep learning framework for tracking endocytic and exocytic carriers at nanoscale. www.biorxiv.org/content/10.64898/20…
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Cell Biology J-Club @cellclub.bsky.social · 20/03/2026
www.nature.com/articles/s41...
nature.com
Visualizing suborganellar lipid distribution using correlative light and electron microscopy - Nature Cell Biology
Lennartz et al. introduce a correlative light and electron microscopy workflow, Lipid-CLEM, combining near-native lipid probes and on-section labelling via click chemistry. Lipid-CLEM quantitatively a...
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bioRxiv Cell Biology @biorxiv-cellbio.bsky.social · 09/02/2026
Structural basis of caveolin-driven membrane bending www.biorxiv.org/content/10.64898/20…
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Jonathan Kaufman @jggkaufman.bsky.social · 21/01/2026
Now finally at least one structure of each of the 6 human AP complexes has been published! We are finally getting close to holistically understanding the differences/intricacies in both recruitment and vesicle formation of this family.
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Briggs Group @briggsgroup.bsky.social · 06/10/2025
The mechanistic basis of cargo selection during Golgi maturation. From Rebecca Taylor, @katciazynska.bsky.social, @jggkaufman.bsky.social & @grigorytagiltsev.bsky.social at @mpibiochem.bsky.social with David Owen and Sean Munro's group @cellbiol-mrclmb.bsky.social | www.science.org/doi/10.1126/...
science.org
The mechanistic basis of cargo selection during Golgi maturation
Resident proteins of the Golgi recycle in vesicles and the protein GOLPH3 enables the COPI vesicle coat to accomplish this.
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Jonathan Kaufman @jggkaufman.bsky.social · 02/09/2025
Super interesting paper on the evolutionary origins of an strange complex of uncertain function.
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Misha Kudryashev @mishakudryashev.bsky.social · 08/06/2025
We have a preprint for you EHD2 forms rings on caveolae necks, in contrast to most EHDs forming helices. We determined its structure on membranes and show that N-term acts as a spacer By Elena, Vasya @vasiliimikirtumov.bsky.social, Jeff &Oli Daumke www.biorxiv.org/content/10.1...
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