iiinova — where your digital self keeps evolving

Long Zhou

@longzhou88.bsky.social

77 followers 134 following 0 posts

Bioenergetics, Mitochondrial complexes, Structural Biologist@Zhejiang University

Posts Replies Media

Reposted by Long Zhou

Alexey Amunts @amunts.bsky.social · 08/04/2026

In a followup with @longzhou88.bsky.social and Yue Liu we move from molecular mechanism to membrane architecture. A giant ETC-ATP synthase assembly containing 10 ATP synthases and 6 respiratory complexes builds long-range periodic OXPHOS arrays on native cristae langtaosha.org.cn/lts/en/prepr... 1/4

26613

Reposted by Long Zhou

Alexey Amunts @amunts.bsky.social · 07/04/2026

65 years after Peter Mitchell’s chemiosmotic theory, we report an association between ATP synthase and the electron transport chain. In the preprint led by @longzhou88.bsky.social, we describe a large supercomplex and show how the supramolecular organization contribute to oxidative phosphorylation 🧵

langtaosha.org.cn

A Supercomplex Incorporating Both Electron Transport Chain and ATP Synthase

The mitochondrial oxidative phosphorylation system powering most aerobic organisms is typically depicted as two spatially segregated machineries(1): electron transport chain complexes I-IV (ETC CI-CIV

37027