The actin-related protein 2/3 (Arp2/3) complex is a central nucleator of branched actin filaments, essential for numerous cellular processes. Using superresolution imaging, we demonstrate that Arp2/3 ...

A network of plasma membrane invaginations called t-tubules plays an essential role in controlling calcium release from the endoplasmic reticulum at the triads during muscle contraction. Although the ...

Explore career opportunities at The Company of Biologists. Join a team passionate about science, publishing and community support.

Explore career opportunities at The Company of Biologists. Join a team passionate about science, publishing and community support.

A biweekly scientific journal publishing high-quality research in molecular biology and genetics, cancer biology, biochemistry, and related fields

Nature - Cryo-electron tomography uncovers the structure of a conserved hexameric ‘portal complex’ that spans the core wall in vaccinia virus, and shows how it is associated with viral...

Uncovering the structure of the poxvirus ‘portal complex’, a channel used by the virus to release its genetic material into infected cells, could help develop new antiviral treatments.

Summary: This Editorial offers an honest look at impact factor trends in developmental biology, explains how Development serves its community, and makes the case that sustaining developmental biology ...

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Noboru Mizushima is Professor of Biochemistry and Molecular Biology at the University of Tokyo, Japan, where he runs a laboratory studying the mechanisms and physiological functions of autophagy and o...

Highlighted Article: MyoF regulates actin organization in T. gondii by assembling into an oligomeric complex that contains multiple motor domains.