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Yury Bykov

@yurabykov.bsky.social
122 followers 142 following 31 posts

Cell biologist, junior group leader at the Technical University of Kaiserslautern (Germany) bio.rptu.de/fgs/quantitative-zellbi…

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Yury Bykov @yurabykov.bsky.social · 03/09/2026
We are looking for a postdoc to investigate the principles of cellular organization using state-of-the-art microscopy! Please repost to help us find a colleague :) Full details here bio.rptu.de/fileadmin/ag...
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Yury Bykov @yurabykov.bsky.social · 24/07/2026
A big milestone for our group: the first research paper submitted! We found that cytosolic translation stress disrupts mitochondrial homeostasis and investigated cytosolic RQC and mitochondrial factors that save it. Preprint: www.biorxiv.org/content/10.6...
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Yury Bykov @yurabykov.bsky.social · 14/07/2026
Really cool study! Few years ago one would say this was not possible...
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Yury Bykov @yurabykov.bsky.social · 19/06/2026
ER has a co-translational protein import mechanism known for decades. But how about mitochondria? Surprisingly, there is still a lot of debate about it! We wrote a comprehensive review on this topic. I hope it is useful :) onlinelibrary.wiley.com/doi/10.1002/...
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Yury Bykov @yurabykov.bsky.social · 18/06/2026
Looks cool! A user friendly GUI tool to adjust and classify the cells detected by CellPose. github.com/biosustain/m...
github.com
GitHub - biosustain/mycol: Fungal spore counting
Fungal spore counting. Contribute to biosustain/mycol development by creating an account on GitHub.
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Yury Bykov @yurabykov.bsky.social · 01/06/2026
This is a great meeting, and our group will be well represented with some new exciting results. There are still places, please spread the word!
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Yury Bykov @yurabykov.bsky.social · 26/05/2026
I applied for the US visa 1.5 years ago, they are still on it. Scientists are indeed a very dangerous category of people.
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Yury Bykov @yurabykov.bsky.social · 14/05/2026
Congrats Higor, Maciej, Simo and Ahmad with this wonderful work!
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Yury Bykov @yurabykov.bsky.social · 04/02/2026
I liked this classy and convincing paper from the Youle lab: intermembrane space endonuclease destroys escaped mtDNA. The escape happens during autophagy, and the vacuole is involved. How? To be determined. www.cell.com/current-biol...
cell.com
The mitochondrial intermembrane space nuclease Nuc1 (endonuclease G) prevents mitophagy-mediated mtDNA escape in yeast
Cupo et al. find that Nuc1 nuclease activity and mitochondrial intermembrane space localization prevent mtDNA escape in yeast. In Nuc1 mutants, inducing mitophagy increases mtDNA escape, whereas inhib...
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Reposted by Yury Bykov
Dr. Fiona @fionachembot.bsky.social · 27/01/2026
Just submitted my first manuscript as an independent PI
image of a golden retriever at computer with a tie with the following caption "i have no idea what im doing"
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Yury Bykov @yurabykov.bsky.social · 13/01/2026
It was a great pleasure to host Svetlana @dodonova-sveta.bsky.social as a guest lecturer at the @rptu.bsky.social. Thanks so much for your fascinating talk about archeal chromatin!
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Yury Bykov @yurabykov.bsky.social · 08/01/2026
Together with @herrmannlab.bsky.social, we wrote this Preview in Mol Cell featuring a new study on the role of glutamine in cancer progression. I was also challenged to draw a "normal" figure. I think it came out nicely :) authors.elsevier.com/c/1mPZE3vVUP... doi:10.1016/j.molcel.2025.12.014
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Yury Bykov @yurabykov.bsky.social · 06/01/2026
Check out the Highlight Issue of Biological Chemistry on the new avenues in organelle biology! I was very honoured to assemble it together with Emma Fenech. We devote it to our mentor Maya Schuldiner on the occasion of her anniversary. Enjoy! www.degruyterbrill.com/journal/key/...
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Yury Bykov @yurabykov.bsky.social · 24/11/2025
This is the last week to apply!
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Yury Bykov @yurabykov.bsky.social · 20/11/2025
Junior professor position at the University of Kaiserslautern! Our Department of Biology is seeking a colleague working with microalgae. This is a wonderful place to do wonderful science with great people! Please, repost :) Further details: jobs.rptu.de/jobposting/1...
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Yury Bykov @yurabykov.bsky.social · 05/11/2025
Very thorough work that applies cryo-ET to measure bilayer thickness. Surprisingly, the missing wedge is not a big problem!
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Yury Bykov @yurabykov.bsky.social · 15/10/2025
Attention new PIs! Here is a workshop to develop as a mentor and project leader, meet your peers and exchange experience. Please repost!
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Reposted by Yury Bykov
GBM (Gesellschaft für Biochemie und Molekularbiologie) @gbmev.bsky.social · 09/10/2025
Registration open: 77. Mosbacher Kolloquium "More than lipidic barriers - New horizons in membrane biology" from March 25-28, 2026 lnkd.in/dgsW4c3 Scientific Organizers: Britta Brügger, Robert Ernst, André Nadler, Christian Ungermann Early registration & poster abstracts until January 31, 2026
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Yury Bykov @yurabykov.bsky.social · 06/10/2025
Here is my take on the two recent papers by Shu-ou Shan and Jonathan Weissman labs. It appears that there might be 'signal inhibition' instead of 'signal recognition' for the mitochondrial proteins in the cytosol. www.sciencedirect.com/science/arti...
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Reposted by Yury Bykov
Journal of Cell Science @jcellsci.bsky.social · 22/09/2025
Din Baruch, Maya Schuldiner, Ofir Klein and colleagues create and validate a proteome-wide yeast library for protein detection and analysis. journals.biologists.com/jcs/article/... #OpenAccess #ReadandPublish
Illustration of the HA library creation and assessment of the efficiency of incorporation.
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Yury Bykov @yurabykov.bsky.social · 26/08/2025
A very cool paper from Shu-ou Shan's lab defines a range of mitochondrial proteins that are imported co-translationally: unexpectedly late recruitment, and evidence for my favourite hypothesis of active inhibition of co-translational import into mitochondria! www.cell.com/cell/abstrac...
cell.com
Principles of cotranslational mitochondrial protein import
Selective ribosome profiling reveals that nearly 20% of mitochondrial proteins in human cells are imported during translation on cytosolic ribosomes. Cotranslational import requires an N-terminal pres...
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Yury Bykov @yurabykov.bsky.social · 31/07/2025
Imagine being an Israeli scientist: you protest the war in Gaza every week, your institute gets bombed, and then the EU cancels your funding in a move that achieves nothing but makes some people in Europe feel morally superior and 'doing the right thing'.
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Reposted by Yury Bykov
Katie Downes @dr-downes.bsky.social · 30/07/2025
Very excited to announce that my first, first author paper, is now on BioRxiv! In this paper we unambiguously show #COPII coated vesicles in unperturbed human cells for the very first time!! Make my day and check it out! www.biorxiv.org/content/10.1... #Cryo-ET #TeamTomo #Cryo-CLEM ❄️🔬❄️🔬❄️🔬❄️🔬
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Yury Bykov @yurabykov.bsky.social · 18/07/2025
The first-ever group trip! This week we visited @simonemattei.bsky.social group at EMBL Heidelberg for a seminar and dinner. Thanks so much for the fantastic day!
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Yury Bykov @yurabykov.bsky.social · 12/07/2025
Recently we discussed at lunch how can molecular biology be brought closer to organismal biology. I remembered this awesome work from Nikolai Sluchanko's lab. Why are grasshoppers green? New, dual-chromophore protein discovered by classic protein purufucation. www.pnas.org/eprint/YMXEU...
pnas.org
A green dichromophoric protein enabling foliage mimicry in arthropods | PNAS
Molecular mechanisms underlying the green insect camouflage have puzzled researchers for over a century. Here, we isolated and identified a green w...
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Yury Bykov @yurabykov.bsky.social · 27/05/2025
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Yury Bykov @yurabykov.bsky.social · 23/05/2025
Yeast labs. Beware!
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Yury Bykov @yurabykov.bsky.social · 07/05/2025
A very exciting day for every yeast genetics lab! Our ROTOR+ from Singer Instruments arrived and was installed. Tons of plans and ideas!
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Reposted by Yury Bykov
Danielle Grotjahn @nanigrotjahn.bsky.social · 01/05/2025
🚨New preprint!🚨 #teamtomo We expanded Surface Morphometrics to quantify membrane thickness from cryo-ET—revealing local variation across organelles. Led by the lab’s first grad student, @mmedina300kv.bsky.social (defending Monday! 🍾) w/ @attychang.bsky.social @hamid13r.bsky.social & @tomo.science
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Yury Bykov @yurabykov.bsky.social · 19/02/2025
The fact that BLAST considered all possible spellings is nice and funny. What's your favorite?
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Yury Bykov @yurabykov.bsky.social · 22/01/2025
It was the greatest pleasure to host @sheinerlab.bsky.social as a visiting lecturer this week and hear the new fascinating story on Toxoplasma mitoribosome! Thank you, Lilach!
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Yury Bykov @yurabykov.bsky.social · 09/01/2025
Hello everyone! New year new blog. Starting 2nd of January our group now consists of me and three PhD students! With three more practical MSc students and a big BSc practical looming over next week this is of course pure chaos but fun!
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