iiinova — where your digital self keeps evolving

Reposted by Alejandro Melero

Simon Bullock @simonbullock11.bsky.social · 18/03/2026

Delighted to announce the posting of our latest preprint, which links stress-induced relocalisation of multiple organelles by dynein to adaptive changes in gene expression in the nucleus (1/n) 🧵 www.biorxiv.org/content/10.6...

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Alejandro Melero @ameleroc.bsky.social · 18/03/2026

Happy to share our latest contribution! How do endosomes get their shape? Well, we show a new role for Arp2/3 in shaping organelles and traffic in fission yeast. New tricks for an old dog!

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Reposted by Alejandro Melero

Noemi Jiménez-Rojo @noemijimenezrojo.bsky.social · 02/04/2025

Extremely grateful to @hfspo.bsky.social and super excited to set this project in motion together with the incredibly talented @ritamateus.bsky.social and @vmonje.bsky.social Zebrafish hide a secret: lipid membranes shaping the crystals behind their stunning structural colors. How? Stay tuned! #HFSP

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Christophe 🔬 Leterrier @christlet.bsky.social · 09/02/2025

Next, work from the Etienne Herzog, @davip-bdx.bsky.social and @fronzeslab.bsky.social using cryo-CLEM and cryo-ET of cortico-striatal dopaminergic synaptosomes to delineate the architecture of non-synaptic modulation: www.biorxiv.org/content/10.1...

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Alejandro Melero @ameleroc.bsky.social · 03/02/2025

This goes beyond my wildest imaginations! Congratulations to @mathilda95.bsky.social @nadlerlab.bsky.social and all the authors! Such a big step forward for membrane biology.

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Albert Pol Lab @albertpol.bsky.social · 02/02/2025

Looking for a PostDoc? Exciting science and great city! Join us @albertpol.bsky.social @albertherms.bsky.social in @idibaps.bsky.social Barcelona to work in an @ercresearch.bsky.social funded project to study how lipid droplets attract and kill bacteria. www.clinicbarcelona.org/uploads/medi...

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Vicente Planelles Herrero @vicenteph.bsky.social · 16/01/2025

Check it out, is finally out!!

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Ishier Raote @ishier.bsky.social · 15/01/2025

Exciting news! #MembraneTrafficking online seminars with @felixmendu.bsky.social @franbottanelli.bsky.social and me are back! Check the spectacular Jan-April 2025 lineup. Details (Zoom links, calendar invites) on the mailing list, Slack group & website: felixcampelo.wixsite.com/membranetraf...

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Marco Hein @marco.heinlab.org · 14/01/2025

Time to share our organelle proteome paper out in @cellcellpress.bsky.social: doi.org/nzwz We created a spatial map of human cells using organelle immunoprecipitation at scale. Locate your fav protein among the 7,600 we mapped across 19 subcellular compartments: organelles.sf.czbiohub.org/ 1/3 🧪

Graphical abstract of the Organelle Profiling paper, showing the workflow:
Endogenously tagged organelle library;
Native IP proteomics;
Data-driven graph clustering;
resulting in a subcellular proteome map with
more than 7,600 proteins localized across 19 subcellular compartments.

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Reposted by Alejandro Melero

Amanda Sierra @sierralab.bsky.social · 15/01/2025

Any #SpatialTranscriptomics people out there interested in studying #microglial development? We need a collaborator based in the Americas or Asia to apply for a #HSPF grant www.hfsp.org/funding/hfsp...

hfsp.org

Research Grants | Human Frontier Science Program

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Daniel P. Moriarity @dpmoriarity.bsky.social · 04/01/2025

"A study of federally funded research projects in the United States estimated that principal investigators spend on average about 45% of their time on administrative activities related to applying for and managing projects rather than conducting active research" www.pnas.org/doi/10.1073/...

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Amanda Sierra @sierralab.bsky.social · 11/12/2024

Happy to share our Perspective on #microglia #pruning and help to answer the questions of whether they are hunters or gatherers of brain #synapses 🧠🧪 #neuroskyence nature.com/articles/s4159…

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Katja Röper @katjaroeper.bsky.social · 14/11/2024

Postdoc position available in the Röper lab at the University of Cambridge @PDN_Cambridge! Join us and discover the role that control of cytoskeletal dynamics, crosstalk and cell adhesion play in the formation of the nephron tube in human renal organoids! jobs.cam.ac.uk/job/48947/

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Lorena Benedetti @lorenabenedetti.bsky.social · 30/11/2024

Kicking off here with some old but gold movies showing ER-lysosome interactions triggered by blue-light excitation of the light-sensitive protein eMags. A shining example of how light can control cellular dynamics! 💡🧫✨

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Luis Bonet-Ponce @lysoluis.bsky.social · 29/11/2024

Stunning paper by Anne Simonsen's lab, identifying BEACH domain-containing proteins as membrane coat proteins involved in endosomal sorting: rupress.org/jcb/article-... Read also @franbottanelli.bsky.social's beauty on ARF1 directing cargo maturation into RE!(www.nature.com/articles/s41...)

rupress.org

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Zunlong Ke @zunlongke.bsky.social · 29/11/2024

A fun journey of full-length EGFR with Dan Leahy and @edwardmarcotte.bsky.social at UT Austin @utaustin.bsky.social. See below: Structure and organization of full-length Epidermal Growth Factor Receptor in extracellular vesicles by cryo-electron tomography www.biorxiv.org/content/10.1...

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The Company of Biologists @biologists.bsky.social · 15/11/2024

- Imaging interorganelle contacts at a glance - Reviews on machine learning, synchrotron X-ray imaging, fluorescence polarisation microscopy and imaging cell-cell junctions - An Editorial from FocalPlane journals.biologists.com/jcs/issue/13...

Imaging interorganelle contacts at a glance poster
Maria Clara Zanellati, Chih-Hsuan Hsu and Sarah Cohen

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cryoEM papers @cryoempapers.bsky.social · 21/11/2024

Characterizing heterogeneity in amyloid formation processes pubmed.ncbi.nlm.nih.gov/39566372/

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Sjors Scheres @sjorsscheres.bsky.social · 21/11/2024

Finally this cool story by @brfalcon.bsky.social is out! 😍😍

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Wallace Marshall @wallaceucsf.bsky.social · 21/11/2024

How do organelles fit together inside a crowded cell? Answering this question requires a way to image many organelles in a whole cell at high resolution with high throughput. Our new preprint shows how to do this in yeast using soft x-ray tomography www.biorxiv.org/content/10.1...

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