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Yumeng Zhan

@ymzhan.bsky.social
31 followers 61 following 2 posts

Postdoc @pilhoferlab.bsky.social @ethz.ch | PhD @ Cramerlab @mpi-nat.bsky.social

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Yumeng Zhan @ymzhan.bsky.social · 21/07/2026
The second story from my PhD is now online! We found that the +1 nucleosome actively functions in the initiation-elongation transition of Pol II transcription. Many thanks to @jabrilgarrido.bsky.social for the great collaboration and everyone involved! authors.elsevier.com/sd/article/S...
cell.com
The +1 nucleosome functions in RNA Pol II transcription initiation and the transition to elongation
By combining biochemical assays and electron cryo-microscopy, Zhan, Abril-Garrido, et al. elucidated key steps of transcription initiation and the transition to elongation in the presence of the +1 nu...
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Reposted by Yumeng Zhan
Pilhofer Lab 🦠❄️🔬 @pilhoferlab.bsky.social · 01/06/2026
🛠️💉It's time for engineering contractile injection systems! @chipericson.bsky.social & @davidschaumann.bsky.social introduce programmable CIS - PROCIS, combining tail length control, non-native cargo loading, and cell retargeting all in one system! www.biorxiv.org/content/10.6... 🧵 1/5
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Reposted by Yumeng Zhan
Julio Abril Garrido @jabrilgarrido.bsky.social · 12/05/2026
Excited to share a preprint which is currently under revision! Together with the amazing @ymzhan.bsky.social in @patrick-cramer.maxplanck.de lab, we describe that the +1 nucleosome actively regulates the transition from transcription initiation to elongation www.biorxiv.org/content/10.6... 1/
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