Nature Reviews Molecular Cell Biology - Single-molecule genomics methods are used to study the activity of regulatory factors on individual DNA molecules genome-wide, thereby enabling...

PomBase is a comprehensive database for the fission yeast Schizosaccharomyces pombe, providing structural and functional annotation, literature curation and access to large-scale data sets

Single-nucleosome imaging/tracking and super-resolution three-dimensional structured illumination microscopy within euchromatic regions show that cohesin-mediated loops constrain condensed euchromatic...

Author summary Telomeres are specialized dynamic protective structures at the ends of eukaryotic chromosomes that must be properly maintained to preserve genome stability. Telomerase extends telomeric...

Recent technological breakthroughs have transformed our understanding of how transcription initiation in eukaryotes is regulated. This Review discusses the dynamics and roles of initiation-relevant pr...

Transcription factors (TFs) differ in their ability to interact with nucleosomes, and most TFs need other TFs to locate their motifs in the human genome. Here, Xiao et al. show that two ELF2 proteins ...

Nucleosomes with their associated modifications organize and regulate the genome. It is unclear how this is integrated with the requirement of replica…

Letter to the Editor

In Schizosaccharomyces pombe , the conserved CHD remodeler Mit1 function within the SHREC remodeler-deacetylase complex (a homolog of the metazoan Mi-2/NuRD complex), which is essential for H3K9 methy...

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The 2027 Gordon Research Conference on Epigenetics will be held in Holderness, New Hampshire. Apply today to reserve your spot.

Abstract. Genomes are pervasively transcribed, leading to stable and unstable transcripts that influence 3-dimensional genome organization and gene regulat

With the introduction of AI, research workflows are evolving quickly. If you're still using Google Scholar to find papers, for instance, you are spending far too much time on something that has…

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