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paveltomancak.bsky.social

@paveltomancak.bsky.social
1.5K followers 433 following 740 posts
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Octavio Reyes-Matte @octavio-rm.bsky.social · 05/10/2026
Having lots of fun with BigVolumeBrowser. Thanks @ekatrukha.bsky.social for the cool plugin! FlyBrain image from FIJI samples BOP Blue and BOP Orange LUTs from @christlet.bsky.social
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Loïc A. Royer 💻🔬🧪 @loicaroyer.bsky.social · 17h
🏁 That's a wrap! The @biohub.org Cell Tracking machine learning challenge on @kaggle.com is over: 4,478 participants, 3,947 teams, 120 countries, 95,438 submissions, tracking every cell of zebrafish embryos. 🧪🔬🧵 kaggle.com/competition... #microscopy
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Ricard Alert Zenón @ricardalert.bsky.social · 05/10/2026
New preprint! Migrating cell clusters have an asymmetric shape, with higher contact angle at the rear and lower at the front. We explained it by treating the tissue as an active droplet driven by asymmetric tractions! arxiv.org/abs/2610.03536
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paveltomancak.bsky.social @paveltomancak.bsky.social · 05/10/2026
EMBO could almost fill a 96 well plate with Nobel Prize winners! 😉
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paveltomancak.bsky.social @paveltomancak.bsky.social · 05/10/2026
Another #Nobel for a method. Congrats; the impact of optogenetics is undeniable.
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Pierre Haas @lepuslapis.bsky.social · 05/10/2026
New #preprint: "Discontinuous buckling from cytoplasmic mechanics in vertex models of epithelia" arxiv.org/abs/2610.03239 More buckling from the #PhD work of @chandraniva.bsky.social.
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Rob Campbell @raacampbell.com · 04/10/2026
Preprint is out! Our BakingTray software turns a 2-photon microscope into a serial-section tomography system for automated whole-organ imaging. ~€35k to convert an existing scope. 11 systems worldwide, >7,000 samples at SWC alone #neuroskyence #microscopy www.biorxiv.org/content/10.6...
A BrainSaw at the Max Planck Institute for Brain Research, Frankfurt. A Nikon 16x water-immersion objective on a 400 µm travel PIFOC allows for fast z-stacks. Samples are imaged and cut in the clear water bath. A Leica VT1000 vibratome is seen to the right with a mounted blade.How BrainSaw works. Samples are embedded in an agarose block, which is glued to a slide and clamped into a water bath. The bath sits on a three-axis stage under a 2-photon microscope; the stage moves the sample for both tile scanning and slicing. The microscope images the exposed face of the block, the vibratome cuts off the imaged layer, and the cycle repeats until the samples have been fully imaged. Data are stitched automatically and are ready for downstream analysis. Logos below: BrainSaw (hardware), BakingTray (acquisition software), StitchIt (stitching).Coronal section of an Sst-tdTomato mouse brain imaged on BrainSaw. tdTomato-expressing cells are shown in yellow, scattered through cortex and hippocampus; tissue autofluorescence is shown in blue.Coronal section of a mouse brain with three neighbouring viral injections targeting layer 5 of V1, expressing mCherry (red), eGFP (green) and BFP (blue). The thick apical dendrites of the labelled neurons are clearly visible, as are their axons projecting to distant targets. Image credit: Alex Fritzl.
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EMBO @embo.org · 02/10/2026
As the EMBO Fellows' and Members' Meeting #EMBOFMM26 comes to an end, Tanmay Bharat is handed over the EMBO Gold Medal. 🧪
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RTG 3142 Biological Making of Materials @rtg3142-bmm.bsky.social · 04/10/2026
We’re excited to launch the Bluesky account for DFG-funded Research Training Group 3142: Biological Making of Materials Follow us to learn more about our research, people and activities. Learn more: www.digs-ils.phd/rtg-bmm #RTG3142 #Biomaterials #Science #Research #DFG
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Yogi Jaeger @yoginho.spore.social.ap.brid.gy · 04/10/2026
We are on the cusp of a de-industrial revolution: thehonestsorcerer.substack.com/p/ri… #TheGreatSimplification
thehonestsorcerer.substack.com
Rising Complexity Cannot End In Any Other Way
Modernity demands a constant growth in energy and material inputs - what could possibly go wrong with that?
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Julia Sero @cellmorphosero.bsky.social · 04/10/2026
www.theguardian.com/artanddesign...
theguardian.com
Comedy wildlife photography award finalists 2026 – in pictures
A selection of the Nikon Comedy Wildlife Awards 2026 finalists – from a shortlist featuring a caiman wearing a wig, a leopard doing a handstand, a strutting white-tailed eagle and a polar bear appeari...
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Bruce Arthurs @brucearthursaz.bsky.social · 04/10/2026
This gave me a good laugh. (from @accordionguy.bsky.social 's "Saturday Picdump" of tech-related memes, cartoons, etc.)
A military execution by firing squad. The condemned person is tied to a wooden post in front of a wall. The condemned man is covered in black ink, with overspray on the wall behind him leaving a negative shadow on the wall. Ten or so feet in front of the prisoner, a large squid lays on the ground, a spray of squid ink stretching between it and the prison.

To one side, two soldiers stand. One, an officer, holds a piece of paper in his hands, looking at it closely.

Caption: "Damn autocorrect."
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Diz-Muñoz Lab @diz-lab.bsky.social · 03/10/2026
We built a fully functional LegoAFM for imaging! 🤩... Today presented at #TürenAuf Tag der #SendungMitDerMaus! ... Remember: Always be curious! ⁉️
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Tim Carmody @tcarmody.bsky.social · 02/10/2026
This is the funniest thing I've seen today, possibly ever
A tweet by SarahStarberry that says "oh god read the vertical axis" on top of a chart measuring AI models' release dates and model numbers rather than any real capabilities
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myosinactncrazy.bsky.social @myosinactncrazy.bsky.social · 03/10/2026
www.biorxiv.org/content/10.6... Mechanical regulation of endocytosis by protein droplet capillary forces
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worm @rfksbrainworm.bsky.social · 02/10/2026
If you ever wondered why visible light is those particular wavelengths, it's because life evolved to see in the narrow range where water is transparent
Diagram of absorption of emf by water. There's a gap right that dips in the 500 nm range
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EMBO @embo.org · 02/10/2026
This week at the EMBO Fellows' and Members' Meeting #EMBOFMM26, visitors could test out the EMBO Science Map. 🧪 It is a visualization of every EMBO Member (round symbols) and Associate Member (square symbols) on a scientific and a geographic map. Explore more here: sciencemap.embo.org
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Dale Moulding @dalemoulding.bsky.social · 01/10/2026
Having seen the news: www.bbc.co.uk/news/article... thought I'd share a cilia movie captured at UCL GOS ICH with Eriomina Shahaj & Vanesa Papastavrou using simple DIC on a Nikon Ti2 with DIC at 60x1.4. 500 fps here slowed down 20 times. Processed with Nikon's denoiseAI and an unsharp mask in Fiji.
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Harmit Singh Malik @harmitmalik.bsky.social · 01/10/2026
The trick… is to never generate any useful data
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Simon Cleary @simoncleary.bsky.social · 01/10/2026
Nikon: '"At this time, we don't see that any rules were violated," it said in a statement.' www.bbc.co.uk/news/article...
bbc.co.uk
Tiny image sparks big backlash in Nikon photo contest
Dr Ning Xu denies he broke the rules of Nikon's annual Small World In Motion contest.
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Gaspar Jekely @jekely.biologists.social.ap.brid.gy · 30/09/2026
If you are interested in serial sectioning for electron microscopy, we have now uploaded a revised version of our paper Shahidi et al: "Volume Electron Microscopy: Tips & Tricks on Micromanipulator-Assisted Serial Sectioning for Array Tomography" […] [Original post on biologists.social]
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André Nadler @nadlerlab.bsky.social · 30/09/2026
This story in @natcellbio.nature.com by the amazing @mathilda95.bsky.social is the final flourish in a series of papers over the last year during which we reported a solution to the lipid imaging problem in biology. Stay tuned for the next chapters!
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Serge Dmitrieff @sergedmi.bsky.social · 30/09/2026
In a way it feels that this debat stems from 2 problems - The funding system has a lot of issues independent of AI, being very wasteful and because... - The objectives of research are being forgotten : we want to increase human knowledge and our capacity to understand and imagine. Not produce stuff
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paveltomancak.bsky.social @paveltomancak.bsky.social · 30/09/2026
Coffee at #embl. Bliss! Big thanks to my sponsors!
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Levayer Lab @levayerr.bsky.social · 29/09/2026
Not sure how the community will be consulted, but if so this will be really critical and time to be vocal...delegating our peer judgement (admittedly imperfect) to LLM feels like removing the cornerstone of how science works. If this is the way it goes, I'd rather become a teacher or bake bread🤷‍♂️
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paveltomancak.bsky.social @paveltomancak.bsky.social · 29/09/2026
No true scientist will outsource the fun of the creative process to a machine. We must focus on finding and eradicating the science operators who will stop at nothing to get more recognition & power. The impostors can be identified. We need to rely more on the good old human interactions.
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European Research Council (ERC) @erc.europa.eu · 29/09/2026
Research evaluation faces growing pressure: demand for competitive research funding is rising, while AI is rapidly changing how proposals can be written and assessed. In this context, the ERC & Science Europe had a workshop with research funding and performing organisations from 5 continents.
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Philippe Batut @philippebatut.bsky.social · 10/09/2026
🧬🔬 Why are enhancers transcribed and how does that impact gene regulation? I’m really excited to share our new paper in @science.org showing that noncoding RNAs control the timing of gene activation in embryos. With Mike Levine #ScienceResearch @columbiamed.bsky.social A few highlights below... 🧵👇
science.org
Noncoding transcription controls the developmental dynamics of long-range gene regulation
The genomic regions regulating gene expression are often themselves transcribed into a variety of noncoding RNAs (ncRNAs). However, the regulatory roles of this noncoding transcription remain largely ...
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Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 29/09/2026
Study today in @natcellbio.nature.com by @mathilda95.bsky.social @nadlerlab.bsky.social @mpi-cbg.de, Honigmann group @biotec-tud.bsky.social & @carldmodes.bsky.social reveals that clathrin-mediated endocytosis sorts proteins but not lipids. Lipids use different routes. www.mpi-cbg.de/news-outreac...
STED image
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Hina Kosakamoto @kosakamotohina.bsky.social · 24/09/2026
Excited to share that our work from RIKEN is now published in Nature! 🎉 We uncovered how protein intake during development shapes lifespan and identified a mechanism that transmits a “nutritional memory” into adulthood. www.nature.com/articles/s41...
nature.com
Lsp2 links early-life diet to adult translation and lifespan in Drosophila - Nature
Isotope tracing is used to determine the fate of larval dietary amino acids in adult flies, and identifies Lsp2 as a key regulator of translation and lifespan that forms the molecular basis of the eff...
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IMAG'IC @imag-ic.bsky.social · 29/09/2026
The IMAG'IC team is back to offer you the "Introduction to the Use of #ImageJ" training course. 22 October 2026 (English) 4 November 2026 (French) institutcochin.fr/formations/f... @institutcochin.bsky.social @upcite.bsky.social @inserm.fr @cnrs.fr
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Iñaki Ruiz-Trillo @multicellgenome.bsky.social · 28/09/2026
We have a new branch in the family tree of animals: Atreyea- a previously unrecognized lineage among the closest unicell relatives of animals. Led by @konsmitsi.bsky.social & @freejakoba.bsky.social together with a fantastic team of collaborators. 🔗 papers.ssrn.com/sol3/papers.... #protistsOnSky
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Magnetic Resonance News @nmr900.bsky.social · 25/09/2026
PostDoc in (Un) Structural Biology of Wnt Signaling, the Tripsianes group, the Central European Institute of Technology (CEITEC) @ceitec.eu Masaryk University, Brno, Czech Republic www.muni.cz/en/about-us/... #NMRjobs #NMRchat #NMR 🧲
muni.cz
PostDoc in (Un) Structural Biology of Wnt Signaling | Masaryk University | MUNI
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Mark Peifer (He, him) @peiferlabunc.bsky.social · 28/09/2026
Are you looking for a postdoc exploring the cell biology of development, defining how cells change shape and move? Do you want to develop a research program & teaching skills preparing you for a position at a college or small University? Our new NIH grant will support those goals 1/n Please share
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Tessa Montague @tessamontague.bsky.social · 29/09/2026
I'm excited to share our new preprint: Generation of a transgenic cephalopod tinyurl.com/pc86jxz8 Cephalopods (cuttlefish, octopus & squid) are crazy critters that dynamically camouflage to their surroundings by changing the color, pattern, & texture of their skin, which they control w their brain.
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Lior Steinberg @steinberg.nu · 24/09/2026
Is it Amsterdam? Copenhagen? No, it's Paris! After years of investment, the French capital has one of the best problems a city can have: bicycle congestion. So if Paris has done it, why wouldn't other cities follow? 📸 Such an amazing photo by @jbpssx.bsky.social
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Zebrafish Rock! 🎃 @zebrafishrock.bsky.social · 27/09/2026
Electrochemical response triggers organ growth, following tail injury in a #zebrafish embryo. Credit to @ritamateus.bsky.social, @nerlielisa.bsky.social, & @liujinghui.bsky.social. #ZebrafishZunday
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Iñaki Ruiz-Trillo @multicellgenome.bsky.social · 28/09/2026
Very grateful to have been part of such a special and emotional day celebrating Sara Bray & Nick Brown at their Retirement Symposium. Two outstanding scientists and, even more importantly, truly wonderful people. Thank you, Sara and Nick, for such a memorable day! #protistsOnSky
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EMBL @embl.org · 28/09/2026
EMBL researchers Robert Prevedel and Simone Mattei are now jointly leading the EMBL Imaging Centre. The new leadership looks forward to boosting tech development and continuing the Centre's push to advance microscopy image analysis through machine learning and other tools. tinyurl.com/26yb5nck
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EMBO Press @embopress.org · 25/09/2026
The EMBO editors look forward to talk science @ 'poster clinic' & 'pitch your paper' sessions (+ over drinks). If you want to look under the bonnet & attend an editorial meeting contact @berndpulverer.bsky.social. @embojournal.org @emboreports.org @embomolmed.org @molsystbiol.org @lsajournal.org
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Joseph W. Brown @josephwb.bsky.social · 26/09/2026
Early-diverging lineages provide little information about ancestors academic.oup.com/sysbio/advan... From @phylieu.bsky.social @sinkingdiatom.bsky.social @omearabrian.bsky.social
academic.oup.com
Early-diverging lineages provide little information about ancestors
Abstract. Large phylogenetic trees are often unbalanced near the root, with a species-depauperate lineage sister to a far more species-rich clade. The spec
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c0nc0rdance @c0nc0rdance.bsky.social · 27/09/2026
Visually, it looks like they're just =disapparating=. Beam me up, Mr. Bug. They have a sort of hidden spring under their bellies, called a 'furca' or 'furcula'. Like having a secret catapult hidden down your trousers. I love the lowering of the antennae just before launch. 💨
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Josh Currie @joshcurrie.bsky.social · 27/09/2026
These are really good
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paveltomancak.bsky.social @paveltomancak.bsky.social · 26/09/2026
Excellent piece. Take them down.
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Christophe 🔬 Leterrier @christlet.bsky.social · 25/09/2026
Today's strategy from the Small Artificial World in Motion winner is to have Singapore colleagues dilute the concerns of world-class microscopists with sycophantic comments
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paveltomancak.bsky.social @paveltomancak.bsky.social · 25/09/2026
As much as I love Czech #science and try to push its academia to new heights, the classical #music art scene is outperforming us on the international stage. As it should be in the land that gave the world Dvořák, Janáček, Smetana. Congratulations Jakub Hrůša 🤠➡️🎩 www.theguardian.com/music/2026/s...
theguardian.com
‘I never choose the cautious option’: Royal Opera’s Jakub Hrůša on collaboration, control and conducting Wagner
One year into the role, the Royal Opera’s music director is taking on the challenge of Parsifal, and, next season, the Ring Cycle. I’m here, and I am courageous says the conductor
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paveltomancak.bsky.social @paveltomancak.bsky.social · 25/09/2026
These people are seriously underestimating the technical capabilities and adaptive behaviors of the scientific community. It is like a clinical trial of a new drug without any oversight or "patient" consent.
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Harmit Singh Malik @harmitmalik.bsky.social · 24/09/2026
I see that @anthropic.com is now competing with PhD students in Biology/Bioengineering labs, whose biggest worry until now was being inevitably scooped by the Feng Zhang and Jennifer Doudna labs. Very different from Wild West days of RT discoveries in my PhD. www.anthropic.com/news/claude-...
anthropic.com
Claude discovers a novel enzyme system
In early results from our new life sciences research lab, Claude agents found an enzyme system whose function is still unknown.
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Davi Bock @dddavi.bsky.social · 24/09/2026
Now I can say: last week we received Notice of Award from NSF on a Midscale Research Infrastructure Design proposal for a National Connectomics and Ultrastructure Volume Observatory (NCUVO) www.uvm.edu/uvmnews/news...
uvm.edu
UVM Launches $19 Million National Observatory to Unlock…
| The University of Vermont
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paveltomancak.bsky.social @paveltomancak.bsky.social · 24/09/2026
He is Groot. Sorry 😜 Apply
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