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Harmit Singh Malik

@harmitmalik.bsky.social
16K followers 4.5K following 2.6K posts

Study genetic conflicts professionally. Try to avoid conflicts in personal life (with mixed results). Fred Hutch Basic Sciences, UW Genome Sciences, HHMI. Posting in a personal capacity. My posts don’t reflect my employers’ opinions.

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Reposted by Harmit Singh Malik
Pleuni Pennings @pleunipennings.bsky.social · 13h
I am hiring a postdoc! Are you interested to work on population genetics/ drug resistance/ data? Want to work in Montpellier, France? Fastq files don't scare you? PhD required, start date hopefully Nov 1! (end date Sep 30 2028) Please share! abetterscientist.wordpress.com/2026/09/29/p...
abetterscientist.wordpress.com
Postdoc position on drug resistance evolution in Montpellier, France
I have some exciting news (again!). I got money from the region (Occitanie) to hire a postdoc (and later an engineer / technician) to work on drug resistance evolution in malaria (P. faciparum) and…
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Reposted by Harmit Singh Malik
Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · 13h
ABSOLUTELY WILD THE LEVELS of incompetence on display here Meanwhile I lost sleep for several days from a reviewer pointing out a paper I should have referenced in a manuscript 🫠
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Kacy Gordon @kacylynn.bsky.social · 28/09/2026
JOB ALERT: UNC Bio is hiring 2 tenure track assistant profs doing molecular, cell, and dev bio. The search is intentionally broad, so please share widely and spread the word! Find more information and apply here: unc.peopleadmin.com/postings/325... Application review begins Nov 1.
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Spokane Rising @spokanerising.com · 29/09/2026
Send Stephen Miller to The Hague.
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Alex Wild @alexwild.bsky.social · 16h
Americans need to recognize that the coup already happened, and is mostly complete.
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🗽LOLGOP🗽 @lolgop.bsky.social · 19h
“You don’t have to stretch to paint this picture: OpenAI models are attacking websites and taking anything they can out of them because that is the business model of the company.”
prospect.org
Why Is Sam Altman a Free Man? - The American Prospect
OpenAI’s models aren’t “going rogue” from their creators as much as they are mimicking them.
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Levayer Lab @levayerr.bsky.social · 28/09/2026
Here it is...by delegating decision to non transparent AI models we generate an incentive for grant applicants to use AI writing to tweak system and the vicious/absurd feedback loop is set (which all started by an overload of grant application driven by AI writing). www.science.org/content/arti...
science.org
U.K. funder uses ‘AI triage’ to reject grant proposals—leaving researchers dismayed
The AI-based assessment, which wasn’t explicitly described in the funding call, has raised privacy and fairness concerns
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Reposted by Harmit Singh Malik
Anita Devineni @anitadevineni.bsky.social · 29/09/2026
The Emory Biology department is hiring a tenure-track ecologist at any rank. Deadline is Nov 1, link below! As I've said many times before, I couldn't ask for a more supportive department. Our faculty colleagues, dept chair, and admin staff are truly awesome ❤️ apply.interfolio.com/191783
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Mark Peifer (He, him) @peiferlabunc.bsky.social · 29/09/2026
For the last 34 years I have been on the faculty of the UNC-Chapel Hill Department of Biology and have never regretted that decision. This year we are hiring TWO new Assistant Professors in the broad area of Molecular, Cell, Developmental Biology 1/n bio.unc.edu
Front page of the website
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Will Ratcliff @wcratcliff.bsky.social · 28/09/2026
New paper out with @kaylastoy.bsky.social: academic.oup.com/evlett/advan...
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Carl T. Bergstrom @carlbergstrom.com · 29/09/2026
"I believe that science derives its authority from something more than mastering the pipeline from data generation to publication. Rather, it comes from interactions within a community of people trained to interrogate evidence and answer for the conclusions they draw from it."
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C. Brandon Ogbunu @cbo.bsky.social · 27/09/2026
In my latest for @undark.org, I compare AI adoption in science to the Ship of Theseus: "If you swap out every wooden plank on a ship over time, is it still the same vessel?" I argue that science derives authority from something more than data generation + publication. undark.org/2026/09/25/o...
undark.org
AI Presents Science with a ‘Ship of Theseus’ Problem
Opinion | AI can replace each part of the scientific process, leaving the enterprise recognizable but devoid of human judgment.
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Tessa Montague @tessamontague.bsky.social · 29/09/2026
I'm excited to share our new preprint: Generation of a transgenic cephalopod tinyurl.com/pc86jxz8 Cephalopods (cuttlefish, octopus & squid) are crazy critters that dynamically camouflage to their surroundings by changing the color, pattern, & texture of their skin, which they control w their brain.
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Reposted by Harmit Singh Malik
Sophien Kamoun @kamounlab.bsky.social · 27/09/2026
I just published: How do we recognize world-class science? Not by the journal it appeared in What I told early-career researchers about prediction, rigour, failure, priors — and the tyranny of bar graphs. kamounlab.medium.com/how-do-we-re...
kamounlab.medium.com
How do we recognize world-class science? Not by the journal it appeared in
What I told early-career researchers about prediction, rigour, failure, priors — and the tyranny of bar graphs.
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Joshua Weitz @joshuasweitz.bsky.social · 28/09/2026
Wonderful profile of our new colleague in the Dept. of Biology in Maryland, @couchmicroscopy.bsky.social with secrets yet to be uncovered into a major evolutionary transition hanging out in murky waters. www.nytimes.com/2026/09/26/s...
nytimes.com
In an $80 Motel Room, a Discovery to Shed Light on the Origins of Life (Gift Article)
A scrappy science project led to a significant discovery: two new species of a rare organism that could elucidate a fundamental transition in the history of life on our planet.
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Mark Peifer (He, him) @peiferlabunc.bsky.social · 28/09/2026
Are you looking for a postdoc exploring the cell biology of development, defining how cells change shape and move? Do you want to develop a research program & teaching skills preparing you for a position at a college or small University? Our new NIH grant will support those goals 1/n Please share
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Reposted by Harmit Singh Malik
Astreia @redoubters.bsky.social · 28/09/2026
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Harmit Singh Malik @harmitmalik.bsky.social · 28/09/2026
Punxsutawney Jill!!! 😂
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Harmit Singh Malik @harmitmalik.bsky.social · 28/09/2026
www.nytimes.com/2026/09/27/s...
nytimes.com
Did Anthropic’s A.I. Really Make a Scientific Discovery on Its Own?
An expert at the University of Copenhagen said his team had been sharing its research with the company’s A.I. model, Claude, and that its new finding matched their work.
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Reposted by Harmit Singh Malik
Alt National Park Service @altnps.bsky.social · 27/09/2026
Who’s ready for No Kings? We’re getting an early start on making signs! ✊💚
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Luca @lucagalletti.bsky.social · 27/09/2026
“Alice Through the Looking Glass" bronze sculpture by Jeanne Argent, located in the Guildford Castle Grounds in Surrey, England.
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biologist077.bsky.social @biologist077.bsky.social · 26/09/2026
I'm amazed by new CRISPR findings for aggressive blood cancers (AML/MDS)! Doctors can edit donor stem cells to remove CD33, letting therapies target cancer without hitting healthy cells. In a trial, 19 of 30 patients maintained blood counts. Incredible protection!
sciencedaily.com
CRISPR could help doctors attack blood cancer without destroying healthy cells
A new Phase 1/2 clinical trial involving 30 patients demonstrates that genetically modifying donor stem cells with CRISPR to remove the CD33 protein can allow targeted cancer therapies to attack aggre
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Casey Drottar @caseydrottar.bsky.social · 26/09/2026
My goodness, what an incredible moment. After Justin Verlander secured the final out of his career, Tigers manager A.J. Hinch came out of the dugout...to summon Verlander's daughter out to embrace her dad on the mound.
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Harmit Singh Malik @harmitmalik.bsky.social · 26/09/2026
I really miss old Twitter and the tension of tweet threads, each limited to 140 characters, which can't be replicated.
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Craig Kaplan @triggerloop.bsky.social · 26/09/2026
I love what he has been doing. Paper out this week even on how to increase drug efficacy by targeting two sites by molecules with linkers.
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Reposted by Harmit Singh Malik
Sarah McAnulty, Ph.D. @sarahmackattack.bsky.social · 26/09/2026
As the executive director of a small nonprofit working my absolute ass off to bring science to this city, hearing that the people negotiating with Drexel and the academy might brush off funding that would provide the kids of our city with access to a science museum *for a year* is boiling my blood.
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Reposted by Harmit Singh Malik
Society for the Study of Evolution @sse-evolution.bsky.social · 25/09/2026
Want to be featured in an upcoming Evolution Exchange interview? We are seeking two to four new faculty members to talk with host Dr. Gina Baucom about their careers and current positions. Nominate yourself or someone else by September 30! forms.gle/tnpK6NYwJZGG...
Text: The Evolution Exchange, a monthly conversation series from the Society for the Study of Evolution. Be our next guest! Nominations due 9/30.
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Reposted by Harmit Singh Malik
Gina Baucom @gbaucom.bsky.social · 26/09/2026
Early career faculty in Evolution? I would love to chat with you!
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Graham Coop @gcbias.bsky.social · 26/09/2026
Well like Snow his name is associated with a pump of toxic sewage causing preventable deaths.
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Harmit Singh Malik @harmitmalik.bsky.social · 26/09/2026
Yeah, which of these people doesn't belong on this list? 🤔
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Rheum Cat @rheumcat.bsky.social · 26/09/2026
"For decades, the Centers for Disease Control and Prevention was the undisputed global leader in public health. Its scientists helped train health officials worldwide. ... [Now] the agency is a skeleton of the powerhouse it was" www.nytimes.com/2026/09/26/h...
nytimes.com
‘Zombified’ C.D.C., Hobbled by Cuts, Struggles to Fulfill Scientific Mission
The agency has lost its independence and nearly a third of its staff, as Health Secretary Robert F. Kennedy Jr. and associates have tightened control.
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Reposted by Harmit Singh Malik
Carl T. Bergstrom @carlbergstrom.com · 26/09/2026
Does my Speak-n-Spell feel pain when I type O-U-C-H? The jury is out. Philosophers and neuroscientists say that's fucking stupid, but I called a guy from the Center for Pretending that Household Electronics Are Sentient and he said there's no way to know for sure.
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Harmit Singh Malik @harmitmalik.bsky.social · 26/09/2026
What about drones with defibrillators being the cause of heart attacks?
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Donovan Anderson @scdja.bsky.social · 26/09/2026
If it’s one I really want, the pre-soaked torta version
static.klipy.com
Birria Tacos with Consommé
Alt: Birria Tacos with Consommé
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Harmit Singh Malik @harmitmalik.bsky.social · 26/09/2026
What food will you bring to a job interview?
static.klipy.com
Dipping Samosa in Sauce
Alt: Dipping Samosa in Sauce
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Reposted by Harmit Singh Malik
Dutchscientist (the real one) @dutchscientist.bsky.social · 25/09/2026
What food will you bring to a job interview?
static.klipy.com
Man Eats Huge Ice Cream Cornet
ALT: Man Eats Huge Ice Cream Cornet
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Reposted by Harmit Singh Malik
Alexander Harms @aharms485.bsky.social · 25/09/2026
The final version of our manuscript on TnSeq in bacteriophages (“HIDEN-SEQ”) is out today – if you have an interesting phage phenotype and want to know the underlying genetic basis, this one is for you! 1/4
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Harmit Singh Malik @harmitmalik.bsky.social · 26/09/2026
Another day, another spate of ‘Vought the f###’ news
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Harmit Singh Malik @harmitmalik.bsky.social · 26/09/2026
Way to keep your eye on what is really important @bsky.app community
Trending topics in bluesky shows that the top discussed topic is the debate over iced coffee at interviews
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Reposted by Harmit Singh Malik
Carl Prothman | Photography @carlprothman.bsky.social · 25/09/2026
Two hours of stars over Mount Rainier, compressed into one minute. 🌌 I photographed this from the White River area as the Milky Way moved across Little Tahoma Peak toward Mount Rainier. Airplanes, satellites, and even a searchlight crossed the frame.
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AndreaVentura @andreaventura.bsky.social · 25/09/2026
Very nice paper from @agnelsfeir.bsky.social and colleagues on the role of MMEJ in ecDNA maintenance and rearrangements. www.nature.com/articles/s41...
nature.com
MMEJ repair of breaks at TA repeats maintains ecDNA and cancer fitness - Nature
Stability of extrachromosomal DNA (ecDNA) relies on microhomology-mediated end joining at fragile TA-rich sites, with FANCM suppressing break formation, suggesting that Polθ disruption may destab...
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Harmit Singh Malik @harmitmalik.bsky.social · 25/09/2026
Tenure process in the age of Trump and Vought
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Leah Houri-Zeevi @leahhouri.bsky.social · 25/09/2026
🩸🩸🩸TODAY WE SHARE TWO MAJOR DISCOVERIES🩸🩸🩸 1. We peered into genomes and brains of the rare mosquitoes that QUIT feeding on blood and found what biting is built from 2. Humans got rid of isoleucine in their blood, malaria suffers from it, and mosquito proteomes budget for it THREADS>
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Angelo Iulianella @aineurolab.bsky.social · 25/09/2026
Folks, it’s been a loooong week. We’re all a bit exhausted, and need some cheering up. How about a couple of jokes? Which biochemicals wash up on beaches? …..nucleotides! 🧪
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Hiten Madhani @hitenmadhani.bsky.social · 25/09/2026
Too easy: Ferroptosis (literal death metal)
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Maitreya Dunham @maitreya.bsky.social · 24/09/2026
Exciting news: @uwgenome.bsky.social will be hiring for two tenure-track faculty positions this year, one open rank and one assistant professor. Both are “Genome Sciences” interpreted broadly so we welcome applicants working in a variety of fields and methods. Ad will be out shortly.
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buvezcocacola @buvezcocacola.bsky.social · 24/09/2026
Seen in Virginia
A bumper sticker reads
I HEAR MIGRANT CHILDREN ALSO HAVE HEARTBEATS
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Sharkmeister77 @sharkmeister77.bsky.social · 24/09/2026
www.reddit.com/media?url=ht...
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Andrew Urquhart @starships-andrew.bsky.social · 24/09/2026
Another step in the #Starship story - they move via a circular intermediate. Helps explain how these elements horizontally transfer and means that we can modify them into transformation vectors (starmids). www.biorxiv.org/content/10.6...
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Maya Voichek @mayavoichek.bsky.social · 24/09/2026
Super excited to share my postdoctoral work at @imbavienna.bsky.social @viennabiocenter.bsky.social - We discovered that some retrotransposons, or "jumping genes" 🧬, are able to spread from cell to cell via a new viral infectivity route. A short thread: 🧵👇 (1/7)
AI-generated illustration of the soma-to-germline transmission of retrotransposons described in our work
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