In Schizosaccharomyces pombe , the conserved CHD remodeler Mit1 function within the SHREC remodeler-deacetylase complex (a homolog of the metazoan Mi-2/NuRD complex), which is essential for H3K9 methy...

Summary: The nucleus–vacuole junction is a prominent contact site linking the nuclear ER and the yeast vacuole. We highlight the physiological implications and metabolic plasticity of this unique orga...

A picture is worth 1,000 words, and this holds true for the plethora of information researchers can obtain from pictures of our cells. The constant processes

King's College London is seeking outstanding and motivated students to join our university and the Agency for Science, Technology and Research (A*STAR).

The U.S. Senate voted on Thursday to approve billions of dollars in funding for federal science agencies, rejecting deep cuts proposed by President Donald Trump in space and other areas.

In this Review, Lusk et al. discuss emerging insights into nuclear pore complex variability with regard to composition and dilation state, and propose nuclear mechanics as a key determinant of driving...

Dai et al. report the localization of BLTP2 in different human cell types and reveal binding partners that mediate its tethering to the PM and to PM-connec

The American Society for Cell Biology (ASCB) is proud to announce the election of 14 outstanding scientists as 2025 ASCB Fellows—a prestigious honor recognizing their exceptional contributions to cell...

The nuclear lamins are extremely long-lived proteins in most cell types. As a consequence, lamin function cannot be effectively dissected with temporal precision using standard knock-down approaches. ...

While organellar compartmentalization is primarily established by the delimiting phospholipid bilayer membranes, the contribution of proteins has been less appreciated. Recently, studies across many r...

Please use this form to submit information identifying specific NIH grants that have been cancelled for any reason after January 20, 2025. Data from this form will be used to update the Rescinded NIH...

Biomedical research impacts all of us. I became curious about how drugs work after my mom was diagnosed with rheumatoid arthritis when I was a small boy. She received “gold shots” as treatment, which ...