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Toru M Nakamura

@tnakamurauic.bsky.social

145 followers 304 following 13 posts

We study telomere maintenance mechanism in fission yeast S. pombe at University of Illinois Chicago. (Lab webpage: nakamura.lab.uic.edu)

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Toru M Nakamura @tnakamurauic.bsky.social · 08/09/2026

I am pleased to share that our story on RPA (Replication Protein A) and telomerase is now out online at PLoS Genetics. journals.plos.org/plosgenetics...

journals.plos.org

Fission yeast RPA–TERT–Tpz1TPP1 complex promotes telomere extension and suppresses telomere recombination

Author summary Telomeres are specialized dynamic protective structures at the ends of eukaryotic chromosomes that must be properly maintained to preserve genome stability. Telomerase extends telomeric...

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Toru M Nakamura @tnakamurauic.bsky.social · 29/04/2026

First-ever preprint from our lab, describing evidence that the RPA-Trt1-Tpz1 complex contributes to telomerase activation in fission yeast. This story began when Yong-jie Xu from Wright State University sent us a collection of 25 Replication Protein A subunit Ssb1 (RPA1) mutants in 2021.

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