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Felix Mikus

@fmikus.bsky.social
676 followers 595 following 40 posts

Postdoc @Dudin lab, UNIGE Previously EMBL HD Lots of microscopy of all different things. If it’s not big enough, make it bigger #UExM Views my own

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Reposted by Felix Mikus
Anna Mankowski @oceanna.bsky.social · 21h
I am still a bit speechless but my main PhD project is finally out in Science Advances. It was a long process, but I am so happy with the final results! Massive thanks to everyone involved, especially my co-authors and everyone involved in sampling! www.science.org/doi/10.1126/...
science.org
Stability in flexibility: Shifting alliances stabilize the symbioses of marine animals over 150 million years
Many animals benefit from microbial symbionts that aid digestion, supply essential nutrients, or provide defense. When this dependence becomes obligate, as in gutless marine oligochaetes that have los...
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Mathilda Lennartz @mathilda95.bsky.social · 30/09/2026
UPDATE!: I am absolutely stoked that the second paper of my PhD is now out in @natcellbio.nature.com :D. We combined lipid imaging, STED microscopy, and mathematical modelling in a super cool team effort to quantify lipid partitioning inside clathrin-coated pits. www.nature.com/articles/s41....
nature.com
Quantification of lipid sorting during clathrin-mediated endocytosis - Nature Cell Biology
Lennartz et al. evaluate lipid enrichment in clathrin-coated pits and observe that the differential lipid partitioning into clathrin-coated pits is largely driven by the lipid asymmetry of the plasma ...
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Holly Moeller @mixotrophe.bsky.social · 27/09/2026
🚨We're hiring!🚨 Join us as a laboratory technician to work on acquired metabolism, from tree-fungal mutualisms to the evolution of protistan photosynthesis. Apply by Oct. 7 at careerspub.universityofcalifornia.edu/psp/ucsb/EMP...
careerspub.universityofcalifornia.edu
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H. B. Beryl Rappaport @hbrappap.bsky.social · 22/09/2026
Our description of fire amoeba, 𝘐𝘯𝘤𝘦𝘯𝘥𝘪𝘢𝘮𝘰𝘦𝘣𝘢 𝘤𝘢𝘴𝘤𝘢𝘥𝘦𝘯𝘴𝘪𝘴, is now online at Cell! Thanks @oliverio.bsky.social and amazing team for questioning the limits of eukaryotes! 🔥 www.cell.com/cell/fulltex...
cell.com
A geothermal amoeba sets a new upper temperature limit for eukaryotes
The amoeba Incendiamoeba cascadensis demonstrates that eukaryotic life can withstand temperatures beyond what was thought possible and sheds light on molecular strategies for survival in extreme heat.
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Felix Mikus @fmikus.bsky.social · 11/09/2026
Thank you a lot for hosting us and showing us around the best places in Granada! It was a pleasure! Looking forward to imaging some of the cultures soon! #ExAME #ExpandThemAll
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Amanda Adam Jansson @amandaadamjasson.bsky.social · 11/09/2026
Back home after an amazing month in Geneva visiting Dudin Lab, @dudinlab.bsky.social and @fmikus.bsky.social☀️ Expanded my mind (and some cells) quite a bit😉😂 Can't wait to visit you again!
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Felix Mikus @fmikus.bsky.social · 11/09/2026
Are you interested in the nuclear envelope and are still lacking a dye for it? Try the lectin concanavalin A in #U-ExM! Together with @baukjeje.bsky.social, @gautamdey.bsky.social and @dudinlab.bsky.social and many collaborators sharing species with us we explored the versatility of this dye
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Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦ @dudinlab.bsky.social · 11/09/2026
Very proud of the team, led by @baukjeje.bsky.social & @fmikus.bsky.social To all of you doing #Expansion #Microscopy #UExM Try Concanavalin A. Its cheap, easy to use & labels the #nuclear #Envelope @moorefound.bsky.social @embl.org @sciencesunige.bsky.social @erc.europa.eu @snsf.ch
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Baukje Hoogenberg @baukjeje.bsky.social · 11/09/2026
Do you want to label the nuclear envelope? Do you work on a non-model species? Try Concanavalin A! We tested ConA on various species across the eukaryotic tree and find it is a very useful ExM-compatible marker for the NE and ER. Read all about it in our preprint: www.biorxiv.org/content/10.6...
biorxiv.org
Concanavalin A as a pan-eukaryotic nuclear envelope marker for expansion microscopy
Across eukaryotes, the nuclear envelope exhibits distinct remodelling strategies during mitosis: complete breakdown (open mitosis), partial disruption (intermediate), or full retention (closed). Howev...
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Florian Wollweber @florianwollweber.bsky.social · 05/09/2026
Exciting news! Our @erc.europa.eu StG project ARCHAEAOLOGY got funded 🎉 We’ll combine cryoET/EM, ExM & spatial omics to explore the subcellular organization of Asgard archaea. Job ads coming soon! 🦠 ❄️ 🔬 #TeamTomo #ArchaeaSky #MicroSky
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Luis Javier Galindo @luisjagago.bsky.social · 04/09/2026
I am extremely happy to announce that I have been awarded an @erc.europa.eu ERC Starting Grant to lead the ProtistEye project! We will be diving into the function, architecture, and diversity of eye-like structures across different protists to better understand their evolution. Stay tuned for more!
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Mathilda Lennartz @mathilda95.bsky.social · 28/08/2026
Today was my last day in Dresden. I am very sad to say good bye to the @nadlerlab.bsky.social and @mpi-cbg.de. I am so grateful for the amazing PhD time I had and all the friends I made along the way. Thanks so so much to André and the whole lab!
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Reese Richardson @reeserichardson.bsky.social · 25/08/2026
A massive update: At least ~15 companies~ are selling scientists antibodies using faked validation data. We've documented 18,000+ manipulated images on 17,000+ products sold by leading laboratory suppliers including Thermo Fisher, Abcam, Santa Cruz Biotechnology, Millipore Sigma and Bio-Techne. 1/🧵
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Holly Moeller @mixotrophe.bsky.social · 07/08/2026
Freaking finally! A massive compilation of data that sat on various desks for almost a decade is finally out. On the positive side, gave me time to learn expansion microscopy and make Fig 1 www.science.org/doi/10.1126/...
science.org
Emergent metabolic parasitism driven by organelle sequestration
Chloroplast-stealing ciliates evolve, increasing reliance on their prey for all aspects of metabolism, including photosynthesis.
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Cameron Thrash @jcamthrash.bsky.social · 05/08/2026
Integration and regulation of stolen organelles in a marine protist academic.oup.com/ismej/advanc... #jcampubs
academic.oup.com
Integration and regulation of stolen organelles in a marine protist
Abstract. Chloroplast-stealing (a.k.a., “kleptoplastidic”) plankton transiently obtain and integrate prey metabolic machinery into their own cells. To do s
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Aafke Gros @aafkegros.bsky.social · 24/07/2026
Microscopy Nodes 3.1 is out for Blender 5.2! 🎉 This has cool new features for conditional masking, working with even larger data (regional upscaling), and data manipulation! Watch the new youtube tutorials that explain the features: www.youtube.com/playlist?lis...
A FIB-SEM plankton visualization where the top shows only the volumetric data of the chromosomes, and the bottom a normally sliced region of the cell. A fluorescence microscopy dataset where a region has been reloaded to be much higher resolution
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Varsha Mathur @varshamathur.bsky.social · 21/07/2026
So happy to share our new paper out now in @natmicrobiol.nature.com! We establish Pirsonia-Coscinodiscus as a model pathosystem and uncover how this tiny parasite infects and kills bloom-forming marine diatoms 🌊🦠 rdcu.be/fuQyF
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Felix Mikus @fmikus.bsky.social · 16/07/2026
Whupwhup! Amazing to have you close by again, looking forward to see what you’ll be up to! 🌱🫖
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Felix Mikus @fmikus.bsky.social · 10/07/2026
Thank you for hosting us @luisjagago.bsky.social! Looking forward to all the fantastic cultures and some expansion shenanigans!
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Holly Moeller @mixotrophe.bsky.social · 02/07/2026
🚨JOB ALERT🚨 We're seeking technicians and postdocs interested in working on decrypting plant-fungal communication as part of a "Fungalphabet" MURI team! (see RFP language below) Official job ads to follow, but please get in touch with me if this sounds like you or someone you know!
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Lena Schindler @lena-schindler.bsky.social · 23/06/2026
I am thrilled to share my PhD work with @nicolettapetridou.bsky.social @embl.org: www.biorxiv.org/cgi/content/... A fun collaboration with Bernat Corominas-Murtra, Adrián Aguirre-Tamaral, @bart-smeets.bsky.social , Jef Vanghel and Tom Belpaire! Read the story in the comments below ⤵️
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Maximilian Ganser @mhganser.bsky.social · 18/06/2026
Tiny unicellular #eukaryotes, big #biomaterial inspiration. Excited to share our Nature Communications study showing that tintinnid ciliates build their chemical- and heat-resistant shells from self-assembling proteins we call Tintinnidorins. doi.org/10.1038/s414... #protistsonsky 1/3
Swimming tintinnid ciliate in its transparent showing the shell-material granules containing the Tintinnidorin proteins accumulated around the circular zone of membranelles of the newly developing cell.
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Laura Rustarazo-Calvo @laura-rustarazo.bsky.social · 16/06/2026
Our beautiful mosaic embryo made it to the cover! 🔥
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EMBO @embo.org · 09/06/2026
Congratulations to Gautam Dey (EMBL) and Omaya Dudin (University of Geneva) for being awarded the EMBO Gold Medal 2026 in recognition of their outstanding contributions to the #LifeSciences in Europe! 🧪 www.embo.org/press-releases/embo-go…
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Laura Rustarazo-Calvo @laura-rustarazo.bsky.social · 02/06/2026
⚡ Our paper is now out in @natphys.nature.com ! This version now includes a detailed molecular characterisation of the optogenetic perturbations, new insights on the relevance of tricellular junctions for tissue morphology, and beautiful light-sheet timelapses. 🔬 www.nature.com/articles/s41...
nature.com
Adhesion-driven rigidity transition decoupled from density-driven jamming triggers epithelial organization in embryonic tissues - Nature Physics
Tissue phase transitions are key to morphogenesis. Now adhesion-driven rigidification is identified as key to epithelial organization but only if uncoupled from density-driven jamming.
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Gautam Dey @gautamdey.bsky.social · 18/05/2026
Multinucleate cells challenge deeply-held assumptions about complexity, ecological success and evolution. Postdoc extraordinaire and gifted writer @mrosjac.bsky.social tackles this subject with aplomb - tell us what you think! www.sciencedirect.com/science/arti... @currentbiology.bsky.social
sciencedirect.com
Multinucleation as a recurring evolutionary strategy for scaling and plasticity
Multinucleate cells — single cells containing multiple nuclei in a shared cytoplasm — are found across the eukaryotic tree of life. Having evolved ind…
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Camilla Autorino @cami-autorino.bsky.social · 18/05/2026
💫 Our paper is now published at @natcellbio.nature.com! So excited about this work done during my PhD at @embl.org in the group of @nicolettapetridou.bsky.social along with our great collaborators! 🐟🎉
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Kenneth Dumack @dumack.bsky.social · 22/04/2026
🌊 Exciting #PhDPosition in #PlanktonEcology at the University of Koblenz, Germany! Work on marine protists with a mix of 🔬 wet lab and 💻 bioinformatics in a 3-year, 60% position. 📅 Apply by 20 May 2026 Please repost/share 🙌 Link: tinyurl.com/yu27knau #Protists #MicrobialEcology #PhD #Ecology
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Felix Mikus @fmikus.bsky.social · 21/04/2026
Our ExM Atlas of eukaryotes is moving along with more and more images coming in - some featured in nature last month! Culture we’re provided by @ccapoban.bsky.social & Julius Lukeš during visits last year www.nature.com/immersive/d4...
nature.com
See the intricate worlds of parasites and algae — March’s best science images
The month’s sharpest science shots, selected by Nature’s photo team.
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CCAP @ccapoban.bsky.social · 16/04/2026
Last few places left! www.ccap.ac.uk/index.php/algaculture2026/
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CCAP @ccapoban.bsky.social · 07/04/2026
The next of our Special Guest Presenters on CCAP’s online training course later this month is Dr Hiral Shah. Dr Shah's talk is entitled "Exploring cytoskeletal diversity across eukaryotes using expansion microscopy" See the link below for course details 👇 www.ccap.ac.uk/index.php/algaculture2026/
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Anthony M. Bonacolta @ambonacolta.bsky.social · 06/04/2026
Attending Protistology Open? Check out @nicolecoots.bsky.social & I's ISOP-sponsored symposium "The Symbiotic Continuum across the Tree of Life" (April 20th @ 11 AM)! We have an amazing lineup of speakers including Ondřej Pomahač, @mixotrophe.bsky.social, & Gillian Gile #ProtistsOnSky #Symbiosis
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Mathilda Lennartz @mathilda95.bsky.social · 23/03/2026
I am extremely excited that my first first-author paper from my PhD is finally out 😆!! We developed a new CLEM workflow to measure lipid densities at the nanoscale. So if you are into lipids and super-resolution imaging approaches, this one is for you: www.nature.com/articles/s41...
nature.com
Visualizing suborganellar lipid distribution using correlative light and electron microscopy - Nature Cell Biology
Lennartz et al. introduce a correlative light and electron microscopy workflow, Lipid-CLEM, combining near-native lipid probes and on-section labelling via click chemistry. Lipid-CLEM quantitatively a...
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André Nadler @nadlerlab.bsky.social · 23/03/2026
It’s incredibly hard to study lipids in biological membranes on the nanoscale. You need near-perfect information on both membrane ultrastructure and lipid density. Lipid-CLEM, now out in @natcellbio.nature.com brought to you by @mathilda95.bsky.social changes that: www.nature.com/articles/s41...
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Manon Demulder @manondemulder.bsky.social · 11/03/2026
Excited to announce I’m starting a new lab at @gmivienna.bsky.social (Vienna BioCentre) in Sept 2026 We study how carbon fixation is inherited and maintained in algae using cryo-ET, imaging, environmental sampling&more Looking for people who want to build the lab together, get in touch! #teamtomo
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Niko Leisch @nikobiota.bsky.social · 24/02/2026
And the best parts about it - it's not over! More and more data is coming out from #TREC and the science will be fantastic to engage with. And my truck? Well it's an #EMBL facility open to the scientific community. If you're interested have a look www.embl.org/groups/mobil... or reach out
embl.org
Mobile Laboratories – A mobile, interdisciplinary facility for light microscopy, flow cytometry, and electron microscopy preparation
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Gautam Dey @gautamdey.bsky.social · 24/02/2026
@embl.org at its best: collaborative, open, transformative, and just the right amount of crazy. Dreaming of mechanistic cell biology *in the natural environment*? Dream no more, rent the AML. www.biorxiv.org/content/10.6... www.youtube.com/watch?v=jepb... #WeFreezeOnTheBeach #ProtistsOnSky 🦠🌍🧪
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Laura Rustarazo-Calvo @laura-rustarazo.bsky.social · 19/02/2026
Excited to share our new review in @dev-journal.bsky.social on tissue phase transitions during development! @karengrace12.bsky.social @nicolettapetridou.bsky.social 🔗 doi.org/10.1242/dev....
doi.org
Tissue phase transitions in development: more than just mechanics
Summary: Tissue material phase transitions are classically thought to regulate tissue deformability. This Review emphasises their unexpected roles in directly influencing growth and patterning signall...
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EMBL @embl.org · 28/01/2026
The origin of eukaryotic cells continues to be one of the greatest mysteries in biology. EMBL Grenoble is excited to welcome Florian Wollweber, who will use cutting-edge imaging techniques to study Asgard archaea — microbes closely related to our earliest ancestors. 🦠🔬 www.embl.org/news/people-...
Researcher Florian Wollweber standing next to a cryo-focused ion beam microscope in a laboratory, with technical infrastructure visible in the background.
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Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦ @dudinlab.bsky.social · 22/01/2026
It was a really fun couple of weeks in the lab ! I also very much enjoyed being in full handle of the #Zeiss 3Dsim scope provided generously for us to explore the various samples.
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Felix Mikus @fmikus.bsky.social · 22/01/2026
Over the last two weeks the Dudin Lab expanded two-fold and it’s been a blast! We are hosting a group of amazing visitors that stopped by with their own species and samples to get started with expansion microscopy. It was a ton of fun, very much looking forward to pictures to come ❤️ #ExpandThemAll
The Dudin lab and their expansion visitors having some well deserved friday drinks and games A group of visitors in their lab coats busily working to get their cells and tissues expanded, stained and ready for microscopy
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FocalPlane @focalplane.bsky.social · 20/01/2026
🔬🔦Our Imaging spotlight from @hiralshah.bsky.social & team highlights their U-ExM atlas of planktonic eukaryotes, including details on how you can explore this wonderful resource. Plus, check out Hiral’s top tips on getting started with expansion microscopy. focalplane.biologists.com/2026/01/20/i...
focalplane.biologists.com
Imaging spotlight: U-ExM atlas of microbial eukaryotes - FocalPlane
Imaging spotlight: U-ExM atlas of microbial eukaryotes - News
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Gautam Dey @gautamdey.bsky.social · 07/01/2026
On this day in 2021, I landed in a snowy, lockdown-silenced Heidelberg to start my lab. 5 years later we are a force to reckon with in our field, and the first generation are striking out on their own. I couldn’t be more proud, & grateful to them and our wonderful collaborators around the world 🌍 🧪
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Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦ @dudinlab.bsky.social · 26/12/2025
Another #notTHECover unfortunately. But this gorgeous, Tron-like vibe, drawn by the amazing @munafomarzia.bsky.social for our recent #ExM work with @gautamdey.bsky.social & @centriolelab.bsky.social will still be printed out in the lab. Read here: www.cell.com/cell/fulltex...
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Holly Moeller @mixotrophe.bsky.social · 11/12/2025
We hope that integrating models with data will unlock new predictive capacity for mixotrophs--and beyond. Huge thanks to Ginger for scouting us, and to collaborators @suleles.bsky.social, @gautamdey.bsky.social, @fmikus.bsky.social, Julian Jacobs, and Kevin Archibald for building skills & ideas!
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Paul & Virginie - Centriole Lab @centriolelab.bsky.social · 10/12/2025
We’re excited to announce the opening of the Geneva Expansion Microscopy Facility (GenExM)! GenExM is a full-service U-ExM platform (U-ExM, Cryo-ExM, iU-ExM), delivering nanoscale imaging. Led by Dr. Olivier Mercey, GenExM welcomes academic & industrial collaborations. 👉 www.unige.ch/genexm/
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Anna Mankowski @oceanna.bsky.social · 07/12/2025
Preprint alert 🔔 Organosulfur compounds support carbon and energy metabolism in chemosynthetic symbiosis. Happy to see this cool collaboration with @organosulfur.bsky.social and others out 🥳
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Gautam Dey @gautamdey.bsky.social · 27/11/2025
So proud to watch Jana turn a side quest into an entire research programme. Couldn’t imagine a more well-deserved outcome. 😍 The mighty yeast reveals what we believe are general principles of centromere evolution! Behind the curtain: communities.springernature.com/posts/counti... #MEvoSky 🧪🌎
communities.springernature.com
Counting Chromosomes: The Simple Idea That Unlocked the Rules Behind Centromere Evolution
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Gautam Dey @gautamdey.bsky.social · 26/11/2025
Our attempt to give multinucleate cells the spotlight they deserve (seriously, they’re everywhere), led by the fearless @mrosjac.bsky.social and with @Markus Ganter doi.org/10.32942/X2M... We’d love your feedback while this goes through the peer review process! #MicroEvoSky #ProtistsonSky 🧪🌏
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Jana Helsen @helsenjana.bsky.social · 26/11/2025
How do new centromeres evolve while staying compatible with the division machinery? Discover it in our new Nature paper! We show centromeres transition gradually via a mix of drift, selection, and sex, reaching new states that still work with the kinetochore. 👉 doi.org/10.1038/s41586-025-09779-1
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