Letter to the Editor

RNA modifications help determine how RNAs are processed and regulated. Here, the authors identify a pathway in fission yeast in which Tgs1-mediated RNA capping recruits RNAi machinery to target crypti...

Macroautophagy/autophagy is a process that degrades intracellular components and is strongly triggered by nitrogen starvation (-N). Some ATG (autophagy related) genes are activated at the transcriptio...

Marin et al. report the role of lamin proteins and the lamin B receptor (LBR) in chromatin positioning at the nuclear periphery. Knockout of all lamins and LBR in mouse embryonic stem cells leads to h...

Argonaute (AGO) mediated slicing of RNA, also known as RNAi, is a highly conserved phenomenon that is evolutionarily linked to the repression of transposons and other repeats. Although RNAi is no long...

Here the authors show that a gene-inactivating protein complex packs inactive genes into a dynamic and accessible structure. The study challenges the traditional views that restricted accessibility an...

The country’s first Sikh prime minister, he introduced free-market reforms that turned India into an economic powerhouse and sought reconciliation with Pakistan.

Can processes occurring in one individuals nervous system influence the physiology of the descendants? Here we explored the provocative hypothesis that parents sensation or perception of environmental...

Abstract. Heterochromatin plays a critical role in regulating gene expression and maintaining genome integrity. While structural and enzymatic components h

The paternal preconception environment has been implicated as a modulator of phenotypic traits and disease risk in F1 offspring. However, the prevalence and mechanisms of such intergenerational epigen...