Reposted by Pilhofer Lab 🦠❄️🔬Asaf Levy @asaflevylab.bsky.social · 17hIn October we are starting year 8 (I think) of the virtual microbiology journal club (on Zoom) with fantatstic speakers, as usual. Most talks are about bacteria. If you (PIs, trainees, anyone interested in science) want to be included in the mailing list - shoot me an email. alevy@mail.huji.ac.il 023
Reposted by Pilhofer Lab 🦠❄️🔬Florian Mayer @florianmayer.bsky.social · 11/09/2026Excited to share our preprint on Ignicoccus cell divison: only the inner membrane divides, progeny cells accumulate in cell clusters and pop-out! www.biorxiv.org/content/10.6... Great work with the labs: @buzzbaum.bsky.social @curiousdina.bsky.social @anja1.bsky.social @tbharat-lab.bsky.socialbiorxiv.orgThe life cycle of an archaeon with multiple membranesMany prokaryotes are diderms. They divide using an FtsZ division ring to simultaneously constrict physically coupled inner and outer membranes to form daughter cells with two membranes. Currently, onl... 07433
Reposted by Pilhofer Lab 🦠❄️🔬Mark Peifer (He, him) @peiferlabunc.bsky.social · 29/09/2026For the last 34 years I have been on the faculty of the UNC-Chapel Hill Department of Biology and have never regretted that decision. This year we are hiring TWO new Assistant Professors in the broad area of Molecular, Cell, Developmental Biology 1/n bio.unc.edu 3150136
Reposted by Pilhofer Lab 🦠❄️🔬Kranzusch Lab @kranzuschlab.bsky.social · 10/09/2026Stunning cryo-ET analysis from the Harrison Lab capturing every stage of how non-membrane viruses infect animal cells www.science.org/doi/10.1126/... 08326
Reposted by Pilhofer Lab 🦠❄️🔬George O'Toole (he/him/his) @geiselbiofilm.bsky.social · 26/09/2026Pls share: Two tenure-track positions in Molecular Microbiology at Virginia Tech. I had a great visit there a couple of years ago! jobs.apply.vt.edu/jobs/assista...jobs.apply.vt.eduAssistant/Associate Professor - Blacksburg, Virginia, United StatesJob Description The Department of Biological Sciences in the College of Science at Virginia Tech seeks applicants for two (2) tenure-track research and teaching positions at the Assistant/Associate ... 01434
Reposted by Pilhofer Lab 🦠❄️🔬Rasmus Jensen @rasmusjensen.bsky.social · 25/09/2026🎉 Out today in Cell: the paper I've been looking forward to sharing for a long time 🎉 We used cryo-ET to find a molecular machine nobody knew existed on the surface of a minimal bacterium, and worked out what it does. 🧵(1/7) #TeamTomo #cryoET 1023190
Reposted by Pilhofer Lab 🦠❄️🔬Ian Yen @ianyyen.bsky.social · 25/09/2026I had a great time at this conference last year and now have the pleasure of helping organize the GRS. I would encourage colleagues to apply and spread the word! 0117
Reposted by Pilhofer Lab 🦠❄️🔬Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦ @dudinlab.bsky.social · 22/09/2026Busy week for #ProtistsOnSky After some planning with Tom Battin & @nikobiota.bsky.social The #Alpine #Microbial Workshop is finally here in #Sion! We're grateful to all funders @sciencesunige.bsky.social #EPFL @embl.org & many supportive foundations & all our collaborators who made this possible. 3204
Reposted by Pilhofer Lab 🦠❄️🔬Craig Kaplan @triggerloop.bsky.social · 25/09/2026Cryo-EM peeps are living the dream www.science.org/doi/10.1126/...science.orgIn-cell structures visualize human pre-ribosome assembly in the nucleolusIn eukaryotes, ribosome biogenesis initiates within the nucleolus, a hallmark multilayered compartment of the nucleus. Structures of pre-ribosomes have been characterized ex situ, but their assembly p... 16731
Reposted by Pilhofer Lab 🦠❄️🔬Simonetta Gribaldo @sgribaldo.bsky.social · 23/09/2026Interested in #archaea, #methane, #cell-envelopes? New paper out @nature.com ! We discovered an enzyme that specifically cleaves the cell wall of methanogens, revealing a new chemical structure of archaeal peptidoglycan, 50 yrs after its first description www.nature.com/articles/s41... #MicroSky 🧵👇nature.com 1412374
Reposted by Pilhofer Lab 🦠❄️🔬Nika Pende @nikapende.bsky.social · 23/09/2026So happy to see this paper finally out 🥳 it took only seven years after the first purification of archaeal peptidoglycan 🤣 Congrats to all the people involved 🥂🍾 And here is the story behind the paper: communities.springernature.com/posts/cracki...communities.springernature.comCracking the Archaeal Cell Wall: How a hydrolase overturned a 50-year-old paradigmUsing bioinformatics, biochemistry, NMR, as well as the newly characterized enzyme ArmA from methanogenic archaea, we revised the existing knowledge on archaeal peptidoglycan structure. At the same ti... 95218
Reposted by Pilhofer Lab 🦠❄️🔬Cathy Spangler @cathyspangler.bsky.social · 22/09/2026I'm excited to share our new preprint, where we show that fine-tuning gold nanoparticle conjugation to different Fab structural elements can produce powerful, rigidly coupled, labeling tools for in-situ cryo-ET. Take a look if you want to see an AuNP in an EM map!🔬🧠 www.biorxiv.org/content/10.6... 14922
Reposted by Pilhofer Lab 🦠❄️🔬Maksim Kalutskii @maksimkalutskii.bsky.social · 23/09/2026Excited to share our new preprint! 📜 Here, we used CALVADOS and ultra-CG models to show how the kinetochore establishes a robust attachment to the dynamic microtubule end. Spoiler: IDRs 🧵 1/n www.biorxiv.org/content/10.6... 17031
Reposted by Pilhofer Lab 🦠❄️🔬Ryo Yokoyama @yokoyama-ryo.bsky.social · 23/09/2026Spatial proteomics reveals carboxysome adaptation and mitochondrial proteome in Paulinella chromatophora: Current Biology www.cell.com/current-biol... @currentbiology.bsky.socialcell.comSpatial proteomics reveals carboxysome adaptation and mitochondrial proteome in Paulinella chromatophoraUsing LOPIT-DC-based spatial proteomics, Cadena et al. map the sub-organellar protein landscape of Paulinella chromatophora, a cercozoan with evolutionary-early-stage photosynthetic organelles. They f... 032
Reposted by Pilhofer Lab 🦠❄️🔬Buzz Baum @buzzbaum.bsky.social · 22/09/2026We are looking for a research assistant! Come join the team: www.jobs.ac.uk/job/DSZ826/r...jobs.ac.ukResearch Support Officer | Cell Biology | Dr Buzz Baum | LMB 2904 at MRC Laboratory of Molecular BiologyStart your UK & international job search for academic jobs, research jobs, science jobs and managerial jobs in leading universities and top... 02846
Reposted by Pilhofer Lab 🦠❄️🔬Earth and Planetary Sciences at ETH Zurich @eth-eaps.bsky.social · 22/09/2026The Department of Earth and Planetary Sciences at ETH Zurich invites applications for the position of Assistant Professor (Tenure Track) of Earth and Planetary Evolution. ethz.ch/en/the-eth-z... Please apply online. The closing date for applications is 15 December 2026.ethz.chAssistant Professor (Tenure Track) of Earth and Planetary EvolutionThe Department of Earth and Planetary Sciences (www.eaps.ethz.ch) at ETH Zurich invites applications for the above-mentioned position. 03148
Reposted by Pilhofer Lab 🦠❄️🔬Swiss National Science Foundation (SNSF) @snsf.ch · 22/09/2026🏆 Biochemist Martin Jinek is the winner of the Swiss Science Prize #MarcelBenoist 2026, considered the Swiss #Nobel Prize. He contributed to the development of molecular scissors, namely CRISPR-Cas9 technology. Read more ➡️ sohub.io/3hs4 66121
Reposted by Pilhofer Lab 🦠❄️🔬Martin Pacesa @martinpacesa.bsky.social · 21/09/2026ʙɪɴᴅᴄʀᴀꜰᴛ2 is out, and we're not waiting for the paper. The full code drops today, free for academic and industry use. We're releasing it early so you can start designing right now, and bring its full power to the current Adaptyv competition. github.com/PacesaLab/Bi... 4292140
Reposted by Pilhofer Lab 🦠❄️🔬Hiro Imachi @hiro-imachi.bsky.social · 17/09/2026An interview article has been published in Nature. It focuses on the cultivation of Asgard archaea (formally, the phylum Promethearchaeota). www.nature.com/articles/d41...nature.comThese bizarre, much-coveted microbes are revealing the origins of complex lifeResearchers are racing to culture a menagerie of exotic organisms and finding lots of surprises along the way. 03915
Reposted by Pilhofer Lab 🦠❄️🔬Vienna BioCenter Scientific Training @vbcscitraining.bsky.social · 18/09/2026Autumn PhD call is OPEN! 30 fully funded positions across diverse life science disciplines. Explore projects in Computation biology 👉 www.vbcphd.at Apply by 10 October Institute of Molecular Biotechnology, Max Perutz Labs Vienna, IMP, Gregor Mendel Institute of Molecular Plant Biology 031
Reposted by Pilhofer Lab 🦠❄️🔬Pedro Beltrao @pedrobeltrao.bsky.social · 18/09/2026Anthropic has used Claude to optimise structure prediction and design code to improve speed and memory efficiency. 2-3X speed improvements on AF3, 5X on OF3, 5X on BindCraft low memory modes to model large assemblies. All released as open source www.anthropic.com/research/cla...anthropic.comHow Claude is uplifting biomolecular modelingAnthropic is an AI safety and research company that's working to build reliable, interpretable, and steerable AI systems. 55517
Reposted by Pilhofer Lab 🦠❄️🔬Roland Hatzenpichler @environmicrobio.bsky.social · 16/09/2026Join us at the "2027 Applied and Environmental GRC: Mechanistic Microbiology for a Complex World" July 18-23, 2027 and GRS "Mechanistic Microbiology Beyond the Model Organism" July 17-18. Applications are open! @thuls.bsky.social and I put together an awesome schedule! www.grc.org/applied-and-...grc.org2027 Applied and Environmental Microbiology Conference GRCThe 2027 Gordon Research Conference on Applied and Environmental Microbiology will be held in South Hadley, Massachusetts. Apply today to reserve your spot. 22014
Reposted by Pilhofer Lab 🦠❄️🔬Dmitri Petrov @petrovadmitri.bsky.social · 17/09/2026We are searching for an Assistant Professor in Evolutionary Biology! Looking for colleagues asking fundamental questions relating to evolutionary processes and drivers of evolutionary patterns. If you think it is you, please do apply! And please repost. facultypositions.stanford.edu/jobs/assista...facultypositions.stanford.eduAssistant Professor in Evolutionary Biology - Stanford University, California, United StatesThe Department of Biology at Stanford University seeks applicants for a tenure-track Assistant Professor in Evolutionary Biology. A successful candidate will conduct research that asks fundamental que... 5151189
Reposted by Pilhofer Lab 🦠❄️🔬Janani Durairaj (Jay) @ninjani.bsky.social · 28/08/2026Some exciting news: I'm joining the University of Lausanne @unil.bsky.social @dbc-unil.bsky.social as an Assistant Professor next month 🎉 My group will work on context-aware deep learning for protein structure, interaction & design. Postdoc and PhD openings coming soon - keep an eye out! 412231
Reposted by Pilhofer Lab 🦠❄️🔬simon-alkema.bsky.social @simon-alkema.bsky.social · 17/09/2026Releasing TOMATO, the TOMogram Annotation TOol! A lightweight Python GUI for going through hundreds of cryo-ET tomograms. Flag what's in each one, grade its quality, and end up with a table you can filter and act on. github.com/alkemasimon/... 15824
Reposted by Pilhofer Lab 🦠❄️🔬Archaea Biotech @archaeabiotech.bsky.social · 17/09/2026Cryo-EM training week at the University of Exeter, hosted by the Daum Lab! 🧊 Theory & sample prep 🔬 Data processing & structure elucidation 🤝 Scientific exchange & team time Thanks to our hosts and everyone who made it a great week! #ARCTECH #CryoEM #Archaea #MSCA #Science 1103
Reposted by Pilhofer Lab 🦠❄️🔬Debnath Ghosal @debnathghosal.bsky.social · 16/09/2026Very pleased to see our recent work on the evolution of complex eukaryotic cells from simple microbial ancestors is featured in this @nature.com News article. www.nature.com/articles/d41....nature.comThese bizarre, much-coveted microbes are revealing the origins of complex lifeResearchers are racing to culture a menagerie of exotic organisms and finding lots of surprises along the way. 042
Reposted by Pilhofer Lab 🦠❄️🔬Cascales Lab @cascaleslab.bsky.social · 11/09/2026New paper in Current Biology @currentbiology.bsky.social 🦠 Why do bacteria ditch their T6SS weapon? E. coli keeps it vs susceptible rivals, but loses it when facing immune ones. Great work by @bobytaillefer.bsky.social & Jonas Desjardins! www.cell.com/current-biol...cell.comExperimental evolution reveals genetic routes for adaptive loss of the antibacterial type VI secretion systemTaillefer et al. show that a bacterial type VI secretion system is lost or attenuated during experimental evolution when it provides no competitive advantage but is maintained in the presence of susce... 02713
Reposted by Pilhofer Lab 🦠❄️🔬Hauke Hillen @haukehillen.bsky.social · 11/09/2026Happy to share our new preprint on the structure of the human mitochondrial RNA degradosome, a central player in organellar RNA metabolism! Work led by graduate student @paulafprado.bsky.social in our group. www.biorxiv.org/content/10.6... 🧵 1/9 19134
Reposted by Pilhofer Lab 🦠❄️🔬Asaf Levy @asaflevylab.bsky.social · 13/09/2026Nice experimental evolution work from @cascaleslab.bsky.social on the mechanisms by which T6SS is lost during evolution when present with T6SS-immune competing bacteria, compared to its maintenance when competitors are T6SS susceptible. www.cell.com/current-biol...cell.comExperimental evolution reveals genetic routes for adaptive loss of the antibacterial type VI secretion systemTaillefer et al. show that a bacterial type VI secretion system is lost or attenuated during experimental evolution when it provides no competitive advantage but is maintained in the presence of susceptible competitors. T6SS inactivation arises through diverse regulatory and structural mutations, revealing how ecological context shapes antibacterial weapon evolution. 083
Reposted by Pilhofer Lab 🦠❄️🔬Basler Lab @basler-lab.bsky.social · 09/09/2026In our new paper, we uncover how Burkholderia switches from antibacterial T6SS-1 to eukaryotic-targeting T6SS-5. Surprisingly, actively turning off T6SS-1 assembly prevents mitochondrial damage and apoptosis. Congrats @christy-chc.bsky.social and the team! link.springer.com/article/10.1...link.springer.comRegulation of Type VI Secretion Systems of Burkholderia during transition to intracellular lifestyle - EMBO ReportsPathogenic bacteria tightly regulate gene expression in response to environmental cues. In Burkholderia species, the Type VI Secretion Systems (T6SS) mediate interbacterial competition and host cell i... 12913
Reposted by Pilhofer Lab 🦠❄️🔬EMBL @embl.org · 09/09/2026Congratulations, Julia Mahamid! The EMBL scientist has been elected to Leopoldina, the German National Academy of Sciences, in recognition of her outstanding contributions to the field of structural cell biology. Learn more: www.embl.org/news/awards-... 010714
Reposted by Pilhofer Lab 🦠❄️🔬Caitie McCafferty @computingcaitie.bsky.social · 09/09/2026I am looking for a lab manager for my group that I will be starting at the @fmiscience.bsky.social in February! We will use in situ structural biology to investigate dynamic ciliary processes. More info here —> bsky.app/profile/comp... #cilia #teamtomo #proteomics #protistsky 34443
Reposted by Pilhofer Lab 🦠❄️🔬Department of Biology, ETH Zurich @eth-dbiol.bsky.social · 10/09/2026Dein Lieblingsfach im Gymnasium war Biochemie, und du möchtest dich auch im Studium weiter in dieses Fach vertiefen? Dann studiere Biologie/Molekulare Biowissenschaften an der ETH Zürich! Raoul erzählt dir, warum dieser Entscheid richtig war. youtube.com/shorts/gqGve... 021
Reposted by Pilhofer Lab 🦠❄️🔬Helmholtz Institute Würzburg @helmholtz-hiri.bsky.social · 07/09/2026Looking to start your own lab? 🧪 #HIRI & @uni-wuerzburg.de are recruiting two junior professors. 🚨 The application deadline is in two weeks. 🧵 More details in the thread below. 👇 0915
Reposted by Pilhofer Lab 🦠❄️🔬Ben Engel @cellarchlab.com · 08/09/2026MemBrain v2 is on @natmethods.nature.com now? I never had a @biorxivpreprint.bsky.social with 164 citations before😅 ...Which is also to say: Thank you to the amazing #TeamTomo community, many of whom not only beta tested, but also contributed diverse training data. This one belongs to all of us! 🤗🔬🧪 011027
Reposted by Pilhofer Lab 🦠❄️🔬Ricardo D. Righetto @lifeonthewedge.bsky.social · 08/09/2026A wild publishing ride to get here... but finally! (first bioRxiv: January 5th, 2024 🙃) Amazing work from @lorenzlamm.bsky.social and colleagues 🤗 Special thanks to the community who jumped early on the boat, sharing feedback and training data to make MemBrain v2 a reality 🙏🏽nature.comMemBrain v2: an end-to-end tool for the analysis of membranes in cryo-electron tomography - Nature MethodsMemBrain v2 enables streamlined analysis of membranes in cryo-electron tomography by providing user-friendly tools for membrane segmentation, membrane protein localization and spatial analysis, suppor... 17125
Reposted by Pilhofer Lab 🦠❄️🔬Lara Krüger @lara-kruger.bsky.social · 09/06/2026📢 We are looking for a Junior Group Leader to join us at @institutcurie.bsky.social! Having joined the department just over a year ago, I can honestly say that it is an exceptionally stimulating and supportive scientific environment, filled with outstanding colleagues — all in the heart of Paris. 19698
Reposted by Pilhofer Lab 🦠❄️🔬Florian Wollweber @florianwollweber.bsky.social · 05/09/2026Exciting news! Our @erc.europa.eu StG project ARCHAEAOLOGY got funded 🎉 We’ll combine cryoET/EM, ExM & spatial omics to explore the subcellular organization of Asgard archaea. Job ads coming soon! 🦠 ❄️ 🔬 #TeamTomo #ArchaeaSky #MicroSky 1513817
Reposted by Pilhofer Lab 🦠❄️🔬Jeremy Baskin @jeremybaskin.bsky.social · 04/09/2026Come be my colleague! Cornell Chemistry & Chemical Biology is hiring TWO tenure-track faculty: assistant professor in chemical biology and open rank in quantum materials. Applications due Oct 15 — academicjobsonline.org/ajo/jobs/32602 #chemjobsacademicjobsonline.orgCornell University, Chemistry and Chemical Biology Job #AJO32602, WDR-00061091 Assistant Professor/Open Rank Professor - Chemistry and Chemical Biology, Cornell University (Ithaca, NY), Chemistry and Chemical Biology, Cornell University, Ithaca, New Y... 03425
Pilhofer Lab 🦠❄️🔬 @pilhoferlab.bsky.social · 03/09/2026Congrats to former lab member @florianwollweber.bsky.social for being awarded an ERC StG!!!🥳 1211
Reposted by Pilhofer Lab 🦠❄️🔬Thibaut Brunet @thibautbrunet.bsky.social · 02/09/2026🚨 New preprint alert! 🚨 Choanoflagellates reorganize their global cytoskeletal architecture within seconds to explore confined microspaces. This is the main PhD work of the amazing @maitefreired.bsky.social www.biorxiv.org/content/10.6... A tread 🧵⬇️biorxiv.orgRapid repurposing of microvillar content drives a flagellate-to-amoeboid switch in the closest relative of animalsAnimal cells extensively remodel their cytoskeleton during differentiation and can notably switch between two major motility modes: flagellum-based swimming and actin-based crawling. We previously sho... 316677
Reposted by Pilhofer Lab 🦠❄️🔬EMBL @embl.org · 03/09/2026Apply to the EMBL Sabbatical Programme now! 📢 This is a great opportunity for senior scientists looking to expand their scientific horizons! You could receive up to €15,000 and be based at any of EMBL’s six sites for 3 to 6 months. 📌 Deadline: 09 Oct 2026 🔗Apply here: bit.ly/sabbatical26 0186
Reposted by Pilhofer Lab 🦠❄️🔬MRC Laboratory of Molecular Biology @mrclmb.ac.uk · 01/09/2026Using advanced microscopy @piotrkolata.bsky.social @a-dsantos.bsky.social @tomdendooven.bsky.social @matteoall.bsky.social have identified the molecular anatomy & organisation of proteasomes in the sperm nucleus. Read more about the study here: mrclmb.ac.uk/news-events/... #LMBResearch 🧪 02711
Reposted by Pilhofer Lab 🦠❄️🔬Serge Mostowy @sergemostowylab.bsky.social · 29/08/2026Septins at the origin? New Opinion piece with @onishilab.bsky.social @wallaceucsf.bsky.social @gautamdey.bsky.social 1398
Reposted by Pilhofer Lab 🦠❄️🔬Michelle Facette @mfacette.bsky.social · 28/08/2026UMass Amherst Dept of Biology is hiring a TT faculty member in Evolutionary Biology! careers.umass.edu/jobs/assista... We have a diverse and wonderful dept - please consider joining us!careers.umass.eduAssistant Professor - Evolutionary Biology - Amherst, Massachusetts, United StatesTitle: Assistant Professor - Evolutionary Biology Executive Area: Academic Affairs College/School/MBU: College of Natural Sciences Department: Biology Work Location: Amherst Schedule: Full Time Work A... 065103
Reposted by Pilhofer Lab 🦠❄️🔬Helmholtz Institute Würzburg @helmholtz-hiri.bsky.social · 24/08/2026🚨 The #HIRI & the Faculty of Medicine of the @uni-wuerzburg.de invite applications for 2️⃣ JUNIOR PROFESSORSHIPS in: 🔵 RNA-BASED INFECTION RESEARCH 🔵 MICROBIAL RNA BIOLOGY 🔵 RNA-BASED MEDICINE Apply by September 21: www.helmholtz-hiri.de/en/jobs-tale... Find an overview in this thread. 🧵👇 (1/5)helmholtz-hiri.deW1 GroupsThe Faculty of Medicine of the Julius-Maximilians-University of Würzburgand theHelmholtz Institute for RNA-based Infection Research (HIRI, Würzburg)jointly open a call for 21019
Reposted by Pilhofer Lab 🦠❄️🔬Typas Lab @typaslab.bsky.social · 29/06/2026How can we harness the vast functional diversity of microbes on our planet? Join us at EMBL Heidelberg from 8–10 December 2026 to hear about ongoing efforts to decode gene function and organisation in human gut microbes, and to present your own research. www.embl.org/about/info/c... 23934
Reposted by Pilhofer Lab 🦠❄️🔬Anthony Vecchiarelli @cellforganized.bsky.social · 26/08/2026My MCDB Dept is hiring, again! Assistant Professor Faculty Search. Please Repost! Applications Due Oct 1st We welcome applications from all areas of cellular/molecular biology in prokaryotes, plants, and animals. More information can be found HERE: jobs.sciencecareers.org/job/679540/a...jobs.sciencecareers.orgAssistant Professor - Ann Arbor, Michigan job with University of Michigan - Molecular, Cellular and Developmental Biology | 679540UNIVERSITY OF MICHIGAN FACULTY POSITION IN CELL & MOLECULAR BIOLOGY AND RELATED FIELDS The Department of Molecular, Cellular, and Developmental B... 04249
Reposted by Pilhofer Lab 🦠❄️🔬Hiten Madhani @hitenmadhani.bsky.social · 27/08/2026Most basic science departments at UCSF are having faculty searches this year. Biochemistry & Biophysics, Microbiology & Immunology, Cellular and Molecular Pharmacology, Physiology and more. We're looking for new and exciting science and nice people. You'll find them all at aprecruit.ucsf.eduaprecruit.ucsf.eduWelcome - AP RecruitUniversity of California, San Francisco Online Faculty Recruitment 311696