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Helmholtz Institute Würzburg

@helmholtz-hiri.bsky.social
1.7K followers 745 following 309 posts

The Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg, Germany is the first institution of its kind worldwide to combine ribonucleic acid (RNA) research with infection biology. www.helmholtz-hiri.de/en/imprint

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Helmholtz Institute Würzburg @helmholtz-hiri.bsky.social · 25/09/2026
👩‍🔬🔬✨ Giving female scientists in infection research greater visibility: The 7th @infect-net.bsky.social Network Meeting brought together 60+ researchers in Würzburg for scientific presentations and networking. Read more: www.helmholtz-hiri.de/en/newsroom/...
helmholtz-hiri.de
Elevating Women in Infection Research
The 7th Infect-Net Network Meeting was held in Würzburg
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Infect-Net @infect-net.bsky.social · 23/09/2026
And last but not least Lisa Tölle presents insights into the research and activities of the @meta-ifif.bsky.social initiative Moms@Science
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Infect-Net @infect-net.bsky.social · 23/09/2026
Afterwards we had a lively panel discussion about age-specific challenges faced by female scientists with @ffaberlab.bsky.social @jeaninerismondo.bsky.social, Michaela Petter and Ina Vorberg moderated by @gabrielepradel.bsky.social
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RNA Society @rnasociety.bsky.social · 22/09/2026
The deadline for @RNASociety awards for graduate students, postdocs, PIs and others is Oct 5th! Awards include a cash prize, complimentary attendance at the RNA Society Meeting in Strasbourg and other benefits! www.rnasociety.org/awards
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Infect-Net @infect-net.bsky.social · 22/09/2026
To get interactive, we will now do a "World Café" on topics selected by the participants. #WorldCafe #networking #connect
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Nature Communications @natcomms.nature.com · 22/09/2026
Antibiotic resistance evolution: A systematic identification of resistance determinants to antisense antibiotics suggests adaptation strategies dependent on the delivery peptide @mulkern.bsky.social @mgalactus.bsky.social @twincore.bsky.social @helmholtzhzi.bsky.social @helmholtz-hiri.bsky.social
dlvr.it
A systematic identification of resistance determinants to antisense antibiotics suggests adaptation strategies dependent on the delivery peptide - Nature Communications
In this study, authors investigate the evolution of bacterial resistance to antisense peptide nucleic acid (PNA) antibiotics. They observe that this typically occurs mainly by reducing drug uptake via mutations in the carrier peptide’s transporter, while resistance to a different carrier peptide stayed low and is easily bypassed by tweaking the drug sequence.
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Infect-Net @infect-net.bsky.social · 22/09/2026
Now, one of our hosts, Franziska Faber, presents her work on programmable RNA antibiotics #Infect-Net #asobiotics #Clostridioides
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Infect-Net @infect-net.bsky.social · 22/09/2026
Welcome speech from our hosts Franziska Faber and Stefanie Kampmeier! Looking forward to a nice meeting to connect #Infect-Net #womeninstem #networking
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Helmholtz Institute Würzburg @helmholtz-hiri.bsky.social · 21/09/2026
The call ends today! ⌛😱👇
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Helmholtz Institute Würzburg @helmholtz-hiri.bsky.social · 18/09/2026
Last week, the MS Wissenschaft docked in Würzburg. During the “Würzburg Future Medicine Day”, experts from politics, medicine, and research—including #HIRI Director Jörg Vogel—discussed how scientific discoveries can be translated into clinical practice. 🔬➡️🏥 www.helmholtz-hiri.de/en/newsroom/...
helmholtz-hiri.de
From Research to Clinical Practice: How Innovation Emerges
Event aboard the MS Wissenschaft
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Helmholtz Institute Würzburg @helmholtz-hiri.bsky.social · 18/09/2026
⏰ Reminder: The deadline is on Monday! Apply by September 21 for one of two junior professorships. Learn more in the thread below. 🧵👇
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Nature Communications @natcomms.nature.com · 16/09/2026
Antibiotic resistance evolution: A systematic identification of resistance determinants to antisense antibiotics suggests adaptation strategies dependent on the delivery peptide @mulkern.bsky.social @mgalactus.bsky.social @twincore.bsky.social @helmholtzhzi.bsky.social @helmholtz-hiri.bsky.social
dlvr.it
A systematic identification of resistance determinants to antisense antibiotics suggests adaptation strategies dependent on the delivery peptide - Nature Communications
In this study, authors investigate the evolution of bacterial resistance to antisense peptide nucleic acid (PNA) antibiotics. They observe that this typically occurs mainly by reducing drug uptake via mutations in the carrier peptide’s transporter, while resistance to a different carrier peptide stayed low and is easily bypassed by tweaking the drug sequence.
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Helmholtz Institute Würzburg @helmholtz-hiri.bsky.social · 16/09/2026
🚨 Last chance to apply for the @rnamed.bsky.social graduate program! 🧬 🗓️ Applications close tomorrow, so don’t miss out: www.uni-wuerzburg.de/en/imib/rnam...
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Helmholtz Institute Würzburg @helmholtz-hiri.bsky.social · 16/09/2026
Check out this recent @natcomms.nature.com paper if you haven’t already! 👇
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Helmholtz Institute Würzburg @helmholtz-hiri.bsky.social · 10/09/2026
🚨Just one week left to apply for the graduate program @rnamed.bsky.social! 🎓🧬 Do you want to contribute to the advancement of precision medicine and targeted molecular therapies? Apply now for one of six #PhD positions in Würzburg, Munich or Regensburg: www.helmholtz-hiri.de/en/jobs-tale...
helmholtz-hiri.de
RNAmed - Future Leaders in RNA-based Medicine
RNAmed takes a holistic approach to endow doctoral students with the necessary knowledge and skills in the fast-growing area of RNA-based medicine.
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Helmholtz Institute Würzburg @helmholtz-hiri.bsky.social · 10/09/2026
🚨 Final call: Applications close tomorrow! ⌛ Don’t miss your chance to apply for one of 16 #PhD positions in infection research: jobs.helmholtz-hzi.de/job/Braunsch... Learn more about the projects: www.helmholtz-hzi.de/en/career/gr...
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Julius-Maximilians-Universität Würzburg @uni-wuerzburg.de · 24/08/2026
Create CAR-T cells and defeat #cancer: A digital #Würzburg research game explains this in an accessible way - from 8 to 11 September @WÜ on board the exhibition ship MS Wissenschaft ➡️https://www.uni-wuerzburg.de/en/news-and-events/news/detail/news/ms-wissenschaft-2026/ 📷 Ilja C. Hendel
A finger touches a touchscreen displaying colourful cells. Picture: Ilja C. Hendel / Wissenschaft im Dialog
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Infect-Net @infect-net.bsky.social · 08/09/2026
Opening for 2 junior professor positions!
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Helmholtz Institute Würzburg @helmholtz-hiri.bsky.social · 07/09/2026
Looking to start your own lab? 🧪 #HIRI & @uni-wuerzburg.de are recruiting two junior professors. 🚨 The application deadline is in two weeks. 🧵 More details in the thread below. 👇
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Wissenschaft im Dialog @w-i-d.de · 04/09/2026
Wie wird aus einer wissenschaftlichen Erkenntnis eine Therapie, die Patient*innen erreicht? Das diskutieren wir in Würzburg an Bord der MS Wissenschaft beim „Dialog an Deck: Von der Forschung in die Klinik: Wie Innovation entsteht“. Seid dabei: ms-wissenschaft.de/de/veranstal... @uni-wuerzburg.de
Die MS Wissenschaft kommt nach Würzburg 08.09.-11.09.2026. Mit der Veranstaltung Dialog an Deck Von der Forschung in die Klinik. Wie Innovation entsteht.Dialog an Deck Von der Forschung in die Klinik
Wie Innovation entsteht 09.09.2026, 17:00 - 19:00 in Würzburg Eröffnung Prof. Dr. Caroline Kisker
Vizepräsidentin der Julius-Maximilians-Universität Würzburg
Prof. Dr. Matthias Frosch
Dekan der medizinischen Fakultät
Impuls
Prof. Dr. Michael Hudecek
Universitätsklinikum WürzburgDialog an Deck
Von der Forschung in die Klinik
Wie Innovation entsteht

Panel 1: Von der Forschung in die Klinik: Wie Innovation entsteht. 

Prof. Dr. Hermann Einsele
Nationales Centrum für Tumorerkrankungen (NCT) WERA
Dr. Sabrina Kraus
Universitätsklinikum Würzburg
Prof. Dr. Wolfgang Kastenmüller
Max-Planck-Forschungsgruppe für Systemimmunologie
Prof. Dr. Jörg Vogel
Helmholtz-Institut für RNA-basierte Infektionsforschung (HIRI)09.09.2026, 17:00 - 19:00 in Würzburg Dialog an Deck
Von der Forschung in die Klinik
Wie Innovation entsteht

Panel 2: Welche Infrastruktur braucht Innovation konkret?

Prof. Dr. Michael Hudecek
Universitätsklinikum Würzburg
Prof. Dr. Ulrike Köhl
Fraunhofer-Institut für Zelltherapie und Immunologie IZI
Joachim Spatz
3. Bürgermeister der Stadt Würzburg
Gunther Schunk
Vogel Stiftung Dr. Eckernkamp
Prof. Dr. Tim J. von Oertzen
Ärztlicher Direktor des Universitätsklinikums Würzburg

Einlass: 16 Uhr
kostenfrei
Bitte anmelden
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Healthcare in Europe (DE) @health-europe-de.bsky.social · 03/09/2026
Asobiotika – eine neue Klasse programmierbarer #Antibiotika – können zur Behandlung resistenter bakterieller #Infektionen eingesetzt werden. Forscher des @twincore.bsky.social, @resist-cluster.bsky.social & @helmholtz-hiri.bsky.social haben nun untersucht, wie sich Bakterien an #Asobiotika anpassen.
healthcare-in-europe.com
Asobiotika – programmierbare Antibiotika auf dem Prüfstand
Wie Bakterien Resistenzen gegen Antisense-Antibiotika entwickeln - und wie sich künftige Therapien weniger anfällig dafür machen lassen
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Jens Hör @jenshoer.bsky.social · 27/08/2026
Join us in Würzburg! Two excellent opportunities to start your own lab in RNA biology 👇
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Helmholtz Institute Würzburg @helmholtz-hiri.bsky.social · 24/08/2026
🚨 The #HIRI & the Faculty of Medicine of the @uni-wuerzburg.de invite applications for 2️⃣ JUNIOR PROFESSORSHIPS in: 🔵 RNA-BASED INFECTION RESEARCH 🔵 MICROBIAL RNA BIOLOGY 🔵 RNA-BASED MEDICINE Apply by September 21: www.helmholtz-hiri.de/en/jobs-tale... Find an overview in this thread. 🧵👇 (1/5)
helmholtz-hiri.de
W1 Groups
The Faculty of Medicine of the Julius-Maximilians-University of Würzburgand theHelmholtz Institute for RNA-based Infection Research (HIRI, Würzburg)jointly open a call for
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Helmholtz Institute Würzburg @helmholtz-hiri.bsky.social · 17/08/2026
🧬 @rnamed.bsky.social is hiring! Apply for one of six fully funded #PhD positions in RNA biology and RNA therapeutics, and work with leading RNA experts in an international, interdisciplinary environment. 📅 Application deadline: September 17, 2026 More info: www.helmholtz-hiri.de/en/jobs-tale...
helmholtz-hiri.de
RNAmed - Future Leaders in RNA-based Medicine
RNAmed takes a holistic approach to endow doctoral students with the necessary knowledge and skills in the fast-growing area of RNA-based medicine.
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Helmholtz Institute Würzburg @helmholtz-hiri.bsky.social · 14/08/2026
Check out this new @natcomms.nature.com paper from @twincore.bsky.social, featuring the labs of @jorg-vogel-lab.bsky.social and @lbarquist.bsky.social, among others. Congratulations to all authors! 👏👇
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NUCLEATE Cluster @nucleate-cluster.bsky.social · 06/08/2026
DNA, RNA, and everything in between. 🧬 We are starting a new series called nucleic notes. Here you can learn fun facts about nucleic acids. Today is about DNA damage. Did you know that each cell repairs ~10,000 DNA lesions every single day? #NUCLEATECluster #DNA
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Jens Hör @jenshoer.bsky.social · 10/08/2026
Do you need to analyze bacterial microscopy data and are looking for an all-in-one tool for Windows or macOS? Check out BactoMate by Lasse Hallenga and Philipp Popp! I'm happy that we were able to contribute to this great work. www.biorxiv.org/content/10.6...
biorxiv.org
BactoMate: an integrated platform for reproducible bacterial microscopy analysis
Quantitative microscopy of microorganisms increasingly produces large, multidimensional datasets, yet their analysis often depends on fragmented workflows spanning file conversion, segmentation, quali...
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Helmholtz Institute Würzburg @helmholtz-hiri.bsky.social · 06/08/2026
Big congratulations to Frank Englert on successfully defending his dissertation on July 29! In the Beisel lab at the Helmholtz Institute Würzburg (HIRI), Frank investigated novel bacterial anti-phage defense systems. Well done! 👏🎓 Learn more: www.helmholtz-hiri.de/en/newsroom/...
Photo: Tatjana Achmedov
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ffaberlab.bsky.social @ffaberlab.bsky.social · 04/08/2026
If you want to work in a collaborative environment, you should check this out! My lab is also offering a PhD position in this call.
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Helmholtz Institute Würzburg @helmholtz-hiri.bsky.social · 04/08/2026
🚨 Exciting #PhD opportunities across multiple labs, including those of @jorg-vogel-lab.bsky.social, @emmanuel-saliba.bsky.social, @cciollimattioli.bsky.social, @ffaberlab.bsky.social & @westermannlab.bsky.social at #HIRI in Würzburg. 🎓🥼 More about the projects: www.helmholtz-hzi.de/en/career/gr...
helmholtz-hzi.de
Joint One Lab Call for Doctoral Researchers 2026
The HZI offers 16 fully funded PhD positions - an exceptional opportunity for curious, young scientist to work in a stimulating environment.
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Infect-Net @infect-net.bsky.social · 21/05/2026
Our next Infect-Net meeting will be very soon! Prof. Dr. Franziska Faber and Prof. Dr. Stefanie Kampmeier invite infection researchers to our 7th network meeting in Würzburg. 📅 22.-23.09.2026 📍Würzburg, Germany Save the date!
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Camilla Ciolli Mattioli @cciollimattioli.bsky.social · 04/08/2026
Offering 1 PhD position under the call in the link
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Jens Hör @jenshoer.bsky.social · 04/08/2026
If you're interested in systems microbiology of intracellular pathogens and joining @cciollimattioli.bsky.social's group, you should check out this call 👇 Highly recommended!
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Junior RNA scientists @jrrnascientists.bsky.social · 01/08/2026
🎉 Happy #RNADay!  Congratulations to the winners of the 2026 @rnasociety.bsky.social RNA Day Art & Baking Contests! Special thanks to Lexogen, the exclusive industry sponsor of the 2026 RNA Society RNA Day Art & Baking Contests, for supporting this initiative.
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Helmholtz Institute Würzburg @helmholtz-hiri.bsky.social · 03/08/2026
Check out this new preprint by @cciollimattioli.bsky.social! 👇👏
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bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 31/07/2026
Image-based transposon screening reveals a flavin reductase that restrains intracellular Salmonella replication in macrophages www.biorxiv.org/content/10.64898/20…
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Helmholtz-Zentrum für Infektionsforschung (HZI) @helmholtzhzi.bsky.social · 31/07/2026
Makrophagen können Krankheitserreger beseitigen, doch manche #Bakterien machen sich diese Zellen als Versteck zunutze. Forscher @helmholtz-hiri.bsky.social & Partner haben einen Mechanismus entdeckt, der das verhindern soll. @faznet.bsky.social berichtet über die Studie. www.faz.net/aktuell/rhei...
faz.net
Überraschung im Immunsystem: Zellen schalten sich selbst ab
Damit Fresszellen des Immunsystems nicht zu Brutstätten für Bakterien werden, gibt es im Körper ein Sicherheitssystem. Forscher aus Würzburg und Marburg haben es entdeckt.
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Helmholtz Institute Würzburg @helmholtz-hiri.bsky.social · 28/07/2026
We were pleased to welcome MDirig Dr Manfred Wolter from the Bavarian State Ministry of Economic Affairs, Regional Development and Energy to Würzburg. During his visit, he toured our future institute building and met with representatives of #HIRI, JMU & UKW. ➡️ www.helmholtz-hiri.de/en/newsroom/...
helmholtz-hiri.de
Cutting-edge research for Bavaria
Dr Manfred Wolter visits HIRI
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Helmholtz Institute Würzburg @helmholtz-hiri.bsky.social · 22/07/2026
Another City Cycling success for the “D15 Bikers”! 🚴💪 34 cyclists from HIRI, IMIB & RVZ covered 7,865 km, once again making them the strongest sub-team at @uni-wuerzburg.de. Congrats to our top 3️⃣ cyclists: Johannes Kullmann, Jonathan Scheler & Tristan Beste. 🏆 ➡️ www.helmholtz-hiri.de/en/newsroom/...
helmholtz-hiri.de
City Cycling 2026: “D15 Bikers” Once Again Best Sub-Team of the University of Würzburg
Cyclists from HIRI, IMIB, and RVZ accumulated a total of 7,865 kilometers
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NUCLEATE Cluster @nucleate-cluster.bsky.social · 20/07/2026
Congrats to NUCLEATE PIs Jörg Vogel & Alexander Westermann on their new paper in PNAS! 👏 Alongside partners at Uni Marburg, they identified SAILR, a long non-coding RNA that acts as an apoptosis regulator. Read more: www.pnas.org/doi/10.1073/... #NUCLEATECluster
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Helmholtz Institute Würzburg @helmholtz-hiri.bsky.social · 20/07/2026
Macrophages are known as the immune system’s “scavenger cells”. Yet some pathogens use them as hiding places. Researchers from HIRI & @unimarburg.bsky.social have discovered an lncRNA called SAILR that helps macrophages balance their response to infection: www.helmholtz-hiri.de/en/newsroom/... (1/3)
Electron microscope image of macrophages. © HZI/Manfred Rohde
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Leon Schulte @schultelab.bsky.social · 17/07/2026
Excited to share our PNAS paper with @jorg-vogel-lab.bsky.social and @westermannlab.bsky.social! We identify SAILR, a human-specific lncRNA that binds 14-3-3β to support macrophage viability—its loss during infection strengthens antimicrobial defense. #RNA www.pnas.org/doi/10.1073/...
pnas.org
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
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Helmholtz-Zentrum für Infektionsforschung (HZI) @helmholtzhzi.bsky.social · 20/07/2026
#Makrophagen sind die „Fresszellen“ des #Immunsystems, doch manche Erreger machen sich gerade diese Zellen als Versteck zunutze. Ein Team des @helmholtz-hiri.bsky.social hat mit Partnern eine #RNA gefunden, die ein "Notausschalter" für infizierte Immunzellen ist. www.helmholtz-hzi.de/media-center...
helmholtz-hzi.de
„Notausschalter“ für Fresszellen
Forschende identifizieren die lncRNA SAILR als Schlüsselregulator in Makrophagen. Sie könnte als Biomarker und Therapieansatz dienen.
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Jens Hör @jenshoer.bsky.social · 15/07/2026
I'm very grateful to receive the Supervisor of the Year award from our graduate school (>350 PIs). This really means a lot to me! Big thanks to my great lab, and I look forward to the coming years of exciting science with everyone 🙂
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Helmholtz Institute Würzburg @helmholtz-hiri.bsky.social · 14/07/2026
Congratulations to @jenshoer.bsky.social, who has been named “Supervisor of the Year” by the @gslsuniwue.bsky.social at @uni-wuerzburg.de! 🎉🥇 Read more: www.helmholtz-hiri.de/en/newsroom/...
helmholtz-hiri.de
Jens Hör is “Supervisor of the Year”
GSLS honors dedicated mentors
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Helmholtz Institute Würzburg @helmholtz-hiri.bsky.social · 09/07/2026
Check out these exciting job opportunities at the NUCLEATE Cluster and apply now! 🔎🧬👇
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Helmholtz Institute Würzburg @helmholtz-hiri.bsky.social · 06/07/2026
Congratulations to Adini Arifah on successfully defending her doctoral thesis today! 👏🎓 She joined #HIRI in 2021 through the graduate program “RNA & Infection” and pursued her #PhD in Chase Beisel’s lab. Learn more about her and her research: www.helmholtz-hiri.de/en/newsroom/...
© HIRI / Luisa Härtig
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Constantinos Patinios @copabio.bsky.social · 29/06/2026
1/4 Excited to share our new preprint on phage genome editing: Targeted DNA nicking enables efficient, single-step and counterselection-free editing of bacteriophage genomes Preprint: lnkd.in/dv4g5kW6
lnkd.in
LinkedIn
This link will take you to a page that’s not on LinkedIn
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Vivek Mutalik @vivekmutalik.bsky.social · 27/06/2026
New preprint!! 🎉 A cool collaborative work with @copabio.bsky.social and Chase Beisel teams on the phage editing technology. @sarshad.bsky.social led the work from our side to validate & characterize the lib. #phage #phagesky www.biorxiv.org/content/10.6... Work supported by: phagefoundry.org
biorxiv.org
Targeted DNA nicking enables efficient, single-step and counterselection-free editing of bacteriophage genomes
Genetic manipulation of bacteriophages is essential for interrogating phage biology and advancing antimicrobial therapies. However, current genome editing approaches can be inefficient, require multip...
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NUCLEATE Cluster @nucleate-cluster.bsky.social · 29/06/2026
We’re excited to introduce the network behind the NUCLEATE Cluster! 🧪 We create a one-of-a-kind ecosystem where nucleic acid research thrives. Proudly collaborating with @helmholtz-hiri.bsky.social, @helmholtzmunich.bsky.social, @mpibiochem.bsky.social. 🧬 #NUCLEATECluster #RNA #DNA
PHOTO: Jan Greune/ Gene Center LMU
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