Sign in

Wallace Marshall

@wallaceucsf.bsky.social
4.2K followers 6.6K following 632 posts

professor at UCSF, engineer turned cell biologist, wants to know how cells solve geometry problems

PostsRepliesMedia
Reposted by Wallace Marshall
American Society for Cell Biology @ascbiology.bsky.social · 01/09/2026
Congratulations to Wallace Marshall of UCSF, recipient of the 2026 Keith R. Porter Lecture, honoring innovative leaders advancing our understanding of cell biology. www.ascb.org/society-news/ascb-anno…
0759
Wallace Marshall @wallaceucsf.bsky.social · 18/08/2026
true or false: ARPA-H is just task-rabbit for biomedical researchers?
030
Wallace Marshall @wallaceucsf.bsky.social · 05/08/2026
Congratulations everyone!
1101
Reposted by Wallace Marshall
American Society for Cell Biology @ascbiology.bsky.social · 03/08/2026
Congratulations to the 2026 ASCB Honorific Award Winners! ASCB is proud to recognize scientists whose research, mentorship, education & leadership are helping shape the future of cell biology. See all the awardees: www.ascb.org/society-news/ascb-anno…
0177
Reposted by Wallace Marshall
American Society for Cell Biology @ascbiology.bsky.social · 03/08/2026
Congratulations to the 2026 ASCB Fellows! ASCB is proud to recognize 15 scientists whose careers have advanced cell biology through outstanding research, leadership, mentorship & service. Meet the 2026 Fellows: www.ascb.org/society-news/fifteen-v…
12713
Reposted by Wallace Marshall
Stand Up for Science! @standupforscience.net · 03/07/2026
🚨 HEADS UP: If you haven't submitted a comment on the OMB proposal yet, there's still time - but it's running out! There are only 10 days left to push back against Russell Vought's attempt to give political appointees unprecedented control over federal research funding. Take Action: zurl.co/Bl59I
Graphic from Stand Up for Science urging action on a federal funding proposal. Large text reads: "10 Days Left" and "Help Us Stop Vought From Destroying American Science." A portrait of Russell Vought appears beside the U.S. Capitol. A banner along the bottom reads: "Submit a comment on the OMB proposal | Link in bio to take action." The Stand Up for Science logo appears in the top left.
110599
Reposted by Wallace Marshall
Sasha | Kai Dao 🔬 @kaidaoscience.bsky.social · 19/06/2026
8 hours. That’s all fish need to heal wounds 🐟⏱️ Why are they so fast compared to humans? I break down the science of rapid regeneration in a microscopy story 🔬 Watch here: youtu.be/Mt9f61adaP0 #FluorescenceFriday #Microscopy
621571
Reposted by Wallace Marshall
Ben Larson @blarson.bsky.social · 25/06/2026
I had a ton of fun the other day talking with @nonresidentdesi.bsky.social and @scifri.bsky.social 's Flora Lichtman and Rasha Aridi about murderous microbes and the things that we are trying to learn from them. Happy for the opportunity to bring some new awareness to the world of protists!
24119
Reposted by Wallace Marshall
epithelial mechanics fan club @epimechfc.bsky.social · 14/06/2026
Heemskerk, I., & Streichan, S. J. (2015). Tissue cartography: compressing bio-image data by dimensional reduction. Nature methods, 12(12), 1139-1142. #EpithelialMechanics doi.org/10.1038/nmet...
doi.org
Tissue cartography: compressing bio-image data by dimensional reduction - Nature Methods
Handling and quantitative image analysis of layered tissues is greatly simplified by cartography with the Image Surface Analysis Environment (ImSAnE), as demonstrated on a variety of specimens, includ...
0101
Reposted by Wallace Marshall
bioRxiv Biophysics @biorxiv-biophys.bsky.social · 14/06/2026
Coupled nucleoplasmic flows and envelope expansion govern the mechanical resistance of the nucleus www.biorxiv.org/content/10.64898/20…
083
Wallace Marshall @wallaceucsf.bsky.social · 13/06/2026
Happy to announce our new preprint is out, in which we analyze single-cell learning in Stentor in the frequency domain, and find that the cell behaves like a fractional-order low pass filter. www.biorxiv.org/content/10.6...
1356
Wallace Marshall @wallaceucsf.bsky.social · 06/06/2026
elizabethginexi.substack.com/p/summary-of... every US scientist needs to submit a comment. the audience is judges down the line, not the OMB itself. refer to specific sections, explain what you think about them especially if the language is unclear or contradictory. you are an expert witness
elizabethginexi.substack.com
Summary of Key Changes in OMB’s Proposed Federal Financial Assistance Rule
Russell Vought is going to destroy American Science
1128
Reposted by Wallace Marshall
Dr. U. Whitcher (U. is for Bear) @yarntheory.bsky.social · 14/05/2026
Wow, this isn't just "we're banning you for 1 year," it's "future work can't be posted until it's peer-reviewed", i.e.,you can no longer use the arXiv for preprints.
2529
Wallace Marshall @wallaceucsf.bsky.social · 14/05/2026
you've heard alot about how cells are or are not crowded at the molecular scale, but what about at the organelle scale? in her new preprint, @marymirvis.bsky.social develops a quantitative way to ask this question in budding yeast - see her thread below www.biorxiv.org/content/10.6...
biorxiv.org
0266
Wallace Marshall @wallaceucsf.bsky.social · 09/05/2026
As part of her RNAseq and proteomics analysis of single-celled learning in Stentor, one of the molecules that Deepa Rajan found to be changing during learning and forgetting was an EF-hand protein. I want to tell you why we think this is interesting
33610
Reposted by Wallace Marshall
Tamas Nagy @tamasnagy.com · 08/05/2026
My PhD work showed that resting neutrophil -> activated/prime neutrophil is a pretty big volume change needed for motility :) Super fast, only a couple minutes to swell so not like other slower changes elifesciences.org/articles/90551
elifesciences.org
Neutrophils actively swell to potentiate rapid migration
Actin-independent water influx complements actin-driven cytoskeletal forces to potentiate chemoattractant-induced migration in primary human neutrophils.
1116
Reposted by Wallace Marshall
Philipp Niethammer @niethammerlab.bsky.social · 08/05/2026
Basically the last 16 years of my lab‘s research is on the role of cell swelling as an alarm signal…initially dismissed by some as fish-specific response, because -obviously- only what is shown in mouse can be important 🙄
121
Reposted by Wallace Marshall
Arthur Prat @arthurpr4t.bsky.social · 21/04/2026
The "Version of Record" of my paper with Mike Woodford is finally there. I am very glad with this paper that points to new laws of psychophysics, which we derived from a carefully considered principle of endogenous efficient coding.
elifesciences.org
Endogenous precision of the number sense
A theory of efficient coding wherein the precision of representations is endogenous, task-dependent, and prior-dependent predicts scaling laws for imprecision and is supported by numerosity perception...
1186
Wallace Marshall @wallaceucsf.bsky.social · 08/05/2026
a big surprise in @deeparajan.bsky.social recent paper identifying molecular pathways of single-cell learning in Stentor, was how effective RNA sequencing turned out to be, revealing CamKII and EF hand proteins that were then shown by RNAi to actually play a role. www.cell.com/current-biol...
1225
Reposted by Wallace Marshall
Yanlan Mao @yanlanmao.bsky.social · 06/05/2026
This exciting paper is now out in PNAS: www.pnas.org/doi/10.1073/...
pnas.org
3D epithelial cell topology tunes signaling range to promote precise patterning | PNAS
Cell behaviors in multicellular organisms are coordinated via both diffusible molecules and by signals based on direct cell–cell contacts. The mode...
27126
Wallace Marshall @wallaceucsf.bsky.social · 08/05/2026
It’s starting to seem like changes in cell volume are turning up in many different cases of cell state transitions. Would be nice to collect examples.
3315
Reposted by Wallace Marshall
Meng Zhu @zhumeng123.bsky.social · 30/04/2026
Cambridge → Boston → Cambridge again: I’m thrilled to return to Cambridge(UK) to open my lab at the Gurdon Institute, University of Cambridge!🥳 (mzhulab.com) We study how dev timing shapes and being shaped by plasticity, evolution & ageing. 🚩Hiring at all levels: pls email me if interested!📩
mzhulab.com
Meng Zhu Lab
We study how development measures time and how timing matters in development, evolution and ageing.
1213734
Reposted by Wallace Marshall
The Washington Post @washingtonpost.com · 03/05/2026
Up close, these tiny organisms in cow stomachs are surprisingly beautiful and evocative. Known as rumen ciliates, these microbes could be playing a more significant role in climate change than previously understood, according to new research. wapo.st/422MqS5
54711
Reposted by Wallace Marshall
SBCF @sbcf.bsky.social · 04/05/2026
Ready for #CellLaVie2026? Program & registration are live! Join us Oct 21–23, 2026 at Institut Pasteur, Paris, for multidisciplinary cell biology, imaging, talks, posters & outreach, w/ Manuel Théry's behind-the-scenes look at the Musée d’Orsay video-mapping project. www.atoutcom.com/cell-la-vie/
03020
Wallace Marshall @wallaceucsf.bsky.social · 05/05/2026
If you are interested in how single cells are able to learn, check out this beautiful article by @niko-kukushkin.bsky.social www.sciencedirect.com/science/arti...
sciencedirect.com
Cellular memory: Learning without building
A new study reveals that habituation in the single-celled ciliate Stentor coeruleus uses the same calcium and kinase signaling as animal memory but do…
0194
Reposted by Wallace Marshall
PROFS @profsuwmadison.bsky.social · 04/05/2026
UW-Madison generated a $13.2 billion economic impact on the state over the last fiscal year. Another $12.4 billion was generated by spinoff companies rooted in UW-Madison research. Vice Chancellor Craig Thompson: "The economic impact...is substantial no matter where you live in the state."
wpr.org
UW-Madison says it generated billions for state's economy last year
A new analysis released by UW-Madison says the university contributed billions in statewide economic impact last fiscal year.
12012
Reposted by Wallace Marshall
Deepa Rajan, PhD @deeparajan.bsky.social · 07/04/2026
We discovered a new species! Our paper on Stentor stipatus is now published @wallaceucsf.bsky.social @aralbright.bsky.social
1155
Reposted by Wallace Marshall
Juan C. Landoni @jclandoni.bsky.social · 24/04/2026
We're hiring! 🔬🏔️ Looking for curious, open-minded, and multidisciplinary #PhD candidates to research at the intersection of #mitochondria, #metabolism, #imaging & #physiology, with the #Alps as a backdrop. Sounds like you or someone you know? Link below! @fbm-unil.bsky.social @unil.bsky.social
15743
Wallace Marshall @wallaceucsf.bsky.social · 03/05/2026
Congratulations to Deepa Rajan for this masterpiece! This is the fourth in her series of papers exploring how a single cell can learn without a brain.
0348
Wallace Marshall @wallaceucsf.bsky.social · 03/05/2026
www.ucsf.edu/news/2026/04...
ucsf.edu
No Brain Required: This Is How the Single-Celled “Stentor” Learns
A team of researchers discover how the stentor, an organism made of a single, gigantic cell, learns without a brain.
0175
Reposted by Wallace Marshall
Deepa Rajan, PhD @deeparajan.bsky.social · 23/04/2026
How can a single cell learn without a brain? We explore this in my paper with @wallaceucsf.bsky.social! We discovered that single cells may learn using molecules similar to those that animal brains use to learn, like CaMKII. Cells can also propagate memory states to their progeny!
426789
Reposted by Wallace Marshall
Frank Santoriello @fsantoriello.bsky.social · 21/12/2025
The final form of my 2nd postdoc paper with the Bassler Lab! Turns out our favorite quorum-sensing phage isn’t a one-off, but rather a member of a globally dispersed family of phages that sense a universal autoinducer. #phagesky #microsky journals.asm.org/doi/10.1128/...
journals.asm.org
A family of linear plasmid phages that detect a quorum-sensing autoinducer exists in multiple bacterial species | mBio
The discovery of quorum-sensing responsive linear plasmid phages has transformed understanding of phage-bacterial interactions by demonstrating inter-domain chemical communication. To date, however, e...
07628
Wallace Marshall @wallaceucsf.bsky.social · 14/12/2025
Lab re-union at #cellbio2025 - great to see everyone again and hear about the interesting new science they are doing!
0330
Wallace Marshall @wallaceucsf.bsky.social · 09/12/2025
The cell is a crowded place where organelles are packed together . In her talk this afternoon Dec 9 at CellBio2025 in the Quantitative Modeling session room 122, Mary Mirvis will show her work using soft x-ray tomography to explore how packing interactions affect organelle shape and interaction.
0191
Wallace Marshall @wallaceucsf.bsky.social · 07/12/2025
The cell is a crowded place where organelles are packed together . In poster B365 at CellBio2025 Monday Dec 8 in the Quantitative Modeling session room 122, Mary Mirvis uses soft x-ray tomography to explore how packing interactions affect organelle shape and interaction.
0336
Wallace Marshall @wallaceucsf.bsky.social · 07/12/2025
Mitochondria form dynamic networks that can be represented as graphs. But the space of graphs is complex. In poster 376 at CellBio2025 Monday Dec 8, Raphie Mostov presents a mathematical approach to represent mitochondria far more simply.
1225
Wallace Marshall @wallaceucsf.bsky.social · 07/12/2025
Stentor is a single cell with a complex cortical pattern showing anterior/posterior polarization In poster 410 at CellBio2025 Monday Dec 8, Yina Hudnall shows a role for posterior-enriched mRNA that encoding DNA binding proteins.
310317
Wallace Marshall @wallaceucsf.bsky.social · 07/12/2025
Stentor is a single cell that can regenerate missing pieces, but how does it know when something is missing? In poster 406 at CellBio2025 Monday Dec 8, Connie Yan shows that conserved cell cycle machinery plays a key role in triggering cellular regeneration.
2317
Wallace Marshall @wallaceucsf.bsky.social · 07/12/2025
The giant ciliate Stentor has a macronucleus that undergoes a dramatic shape change during cellular regeneration. In poster 038 at CellBio2025 Monday Dec 8, I present work by Isabella Ibalio showing that histone modifications correlate with these dramatic nuclear shape changes.
1215
Wallace Marshall @wallaceucsf.bsky.social · 07/12/2025
Flagellar length control in Chlamydomonas is a paradigm for organelle size regulation. In poster 163 at CellBio2025 Sunday Dec 7, I present work by Hiro Ishikawa using a synthetic biology approach to test a length-sensing model based on diffusion of kinesin in flagella
04910
Wallace Marshall @wallaceucsf.bsky.social · 07/12/2025
Flagellar length control in Chlamydomonas is a paradigm for organelle size regulation. In poster 155 at the CellBio2025 meeting Sunday Dec 7, Ximena Garcia Arceo uses Lithium, which increases intraflagellar transport, as a tool to probe how length-altering mutants work.
2267
Wallace Marshall @wallaceucsf.bsky.social · 07/12/2025
The low Reynolds number of cytoplasmic flow which makes mixing hard. In poster 359 at the CellBio2025 meeting Sunday Dec 7, Ulises Diaz shows how giant cells leverage reversible actin gel assembly to drive rapid mixing of cytoplasm, faster even than "chaotic mixing" schemes.
1143
Wallace Marshall @wallaceucsf.bsky.social · 05/12/2025
Cells can hunt prey, solve mazes, and learn from past experience. Does this mean they can think, at some level? Find out more at our upcoming session on "Cell Behavior and Cognition" at the ASCB/EMBO #cellbio2025 meeting, Saturday 1-3 pm rm 115.
46916
Reposted by Wallace Marshall
Seth Bordenstein @symbionticism.bsky.social · 05/12/2025
Reach out and touch somebody’s future organelle? Make this place a better world, if you can.
061
Wallace Marshall @wallaceucsf.bsky.social · 05/12/2025
My first ever time doing a podcast - part of “that’s absurd, please elaborate”, recorded live at the Bay Area Science Festival. thatsabsurdshow.com Discussing two topics- does saturable transport mean you can eat as much as you want? and what would happen if tardigrades were a lot bigger?
thatsabsurdshow.com
That's Absurd Please Elaborate
0185
Reposted by Wallace Marshall
Gautam Dey @gautamdey.bsky.social · 25/11/2025
Check out that spindle 🤩🔥 At 63C, most eukaryotic cells would be busy exploding noisily, forget even trying to divide. The microbial universe never ceases to astound 😍 Thanks for letting us be a tiny part of this! #ExpandThemAll
16215
Reposted by Wallace Marshall
Aaron Rupar @atrupar.com · 28/11/2025
“You’re a stupid person” — Trump lashes out at a reporter who presses him on the fact that the suspected DC shooter was actually thoroughly vetted before he was let in the US from Afghanistan
117764661951
Reposted by Wallace Marshall
Dylan Burnette @mag2art.bsky.social · 24/11/2025
Some cells are just in it for the drama! The bottom 5 microns of cells videoed through a microscope by @EmmaKoory. The middle cell rounds up (for fun?) and subsequently rounds up to divide. We missed so much of the action by just sampling the bottom. @CellBiology
0288
Reposted by Wallace Marshall
Gal Haimovich ☣ 🧪🔬🎗 @grnfluoresceblg.bsky.social · 25/11/2025
media.tenor.com
a cartoon of a rabbit carrying a yellow object
ALT: a cartoon of a rabbit carrying a yellow object
2192