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Thibaut Brunet

@thibautbrunet.bsky.social
5.8K followers 3K following 588 posts

Evolutionary cell biology / evolution of morphogenesis / animal origins / choanoflagellates @institutpasteur.bsky.social research.pasteur.fr/en/team/evoluti…

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Reposted by Thibaut Brunet
Levayer Lab @levayerr.bsky.social · 7h
Not sure how the community will be consulted, but if so this will be really critical and time to be vocal...delegating our peer judgement (admittedly imperfect) to LLM feels like removing the cornerstone of how science works. If this is the way it goes, I'd rather become a teacher or bake bread🤷‍♂️
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paveltomancak.bsky.social @paveltomancak.bsky.social · 7h
No true scientist will outsource the fun of the creative process to a machine. We must focus on finding and eradicating the science operators who will stop at nothing to get more recognition & power. The impostors can be identified. We need to rely more on the good old human interactions.
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Mark Peifer (He, him) @peiferlabunc.bsky.social · 28/09/2026
Are you looking for a postdoc exploring the cell biology of development, defining how cells change shape and move? Do you want to develop a research program & teaching skills preparing you for a position at a college or small University? Our new NIH grant will support those goals 1/n Please share
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EMBL @embl.org · 19h
🔬A new study by EMBL researchers reveals the incredible molecular dynamics occurring right beneath the surface in living cells. The research identifies cell membrane-to-cortex attachments as a key regulator of the mechanical forces that shape the cell surface. Learn more: sl1nk.com/ydkuvvo
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Iñaki Ruiz-Trillo @multicellgenome.bsky.social · 20h
Nice work @thibautbrunet.bsky.social et al. It fits a view we find compelling: the ancestor of animals may have switched between different cell states, and perhaps different multicellular entities. Maybe we should reconstruct an ancestral life cycle, not an ancestral cell type. #protistsOnSky
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Alfonso Martinez Arias @amartinezarias.bsky.social · 20h
Intriguing set of observations on how ‘dual-aggregate gastruloids’ lead to the emergence of foregut-pharyngeal mesoderm co-development and patterning www.biorxiv.org/content/10.6... #gastruloids #MustRead
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Will Ratcliff @wcratcliff.bsky.social · 28/09/2026
New paper out with @kaylastoy.bsky.social: academic.oup.com/evlett/advan...
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Marc Robinson-Rechavi @marcrr.bsky.social · 28/09/2026
I'm not writing in the NYT and I won't word it carefully: it's clear that AI companies are stealing researchers' work (and why wouldn't they? they steal artists' and journalists' work with no consequences), and I warned my group about it this morning.
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Jez Carlton @jezcarlton.bsky.social · 28/09/2026
Hey! Submit your papers, and spread the word, this will be great! Thanks for inviting us @jcellsci.bsky.social and great to work with @pihanson.bsky.social on this issue!
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Lior Steinberg @steinberg.nu · 24/09/2026
Is it Amsterdam? Copenhagen? No, it's Paris! After years of investment, the French capital has one of the best problems a city can have: bicycle congestion. So if Paris has done it, why wouldn't other cities follow? 📸 Such an amazing photo by @jbpssx.bsky.social
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Iñaki Ruiz-Trillo @multicellgenome.bsky.social · 28/09/2026
We have a new branch in the family tree of animals: Atreyea- a previously unrecognized lineage among the closest unicell relatives of animals. Led by @konsmitsi.bsky.social & @freejakoba.bsky.social together with a fantastic team of collaborators. 🔗 papers.ssrn.com/sol3/papers.... #protistsOnSky
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Daniel Krentzel @danielkrentzel.bsky.social · 28/09/2026
And here's a nice résumé of our @natcomms.nature.com paper for the grand public 👇 📃 www.nature.com/articles/s41...
nature.com
Deep learning recognises antibiotic modes of action from brightfield images - Nature Communications
Authors present a deep learning model that recognises antibiotic modes of action (MoA) directly from brightfield images. Their proposed method complements traditional growth inhibition assays in the s...
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Pierre de Villemereuil @pdevillemereuil.bsky.social · 28/09/2026
With fieldwork, I didn't get to advertise our (not so now) new paper on the quantitative genetics of growth in the 🦎 in @journal-evo.bsky.social: dx.doi.org/10.1093/evol... It's an exciting paper paper in which we disentangle what it means to treat the whole growth curve as a function-valued trait!
dx.doi.org
Quantitative genetics of lifetime growth curves in a lizard
Abstract. Body size is an iconic trait in quantitative genetics. For species with indeterminate growth however, growth curve, a function-valued trait, is t
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noam @prywes.bsky.social · 27/09/2026
This is such a great piece of work about an amazing evolutionary story, every part of this is incredible. Congrats @rudycadenabioevo.bsky.social @evanowack.bsky.social Among other surprises, oxygen scavenging instead of photorespiration is not something I was expecting!
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Levayer Lab @levayerr.bsky.social · 24/09/2026
Only one week left to apply ! Check below for more details but the course will be great. Please spread the word 🙏
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Alex de Mendoza @alexdemendoza.bsky.social · 25/09/2026
For those of you who, like me, missed the Vatican #EvoDevo: www.pas.va/en/events/20..., don't worry, there will be a more earthly local version next week (Friday) in Cambridge Dept of Zoology, program here: londonevodevo.co.uk. Can't promise cardinal vestments in the background though.
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Katrina Velle @katrinavelle.bsky.social · 26/09/2026
In case it is useful for anyone out there, here’s a thread of papers that have worked well for journal clubs in my advanced cell bio class (~15 undergrads + 5 grad students) Please add your own favorites, or your own work if you think it’s suitable! (1/6)
static.klipy.com
ALT:
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Caroline Bartman @cbartman.bsky.social · 26/09/2026
NEVER do macropinocytosis at a job interview. It’s simple, folks.
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Michael Way @drmichaelway.bsky.social · 26/09/2026
Arp2/3 iso-complexes strike again! Axonal actin ring assembly and maintenance involves different iso-complexes that change expression during neuronal maturation 🎉 Great collaboration with Ana Rita Costa & Monica Sousa @ i3S in Porto www.i3s.up.pt/research-gro... www.science.org/doi/10.1126/...
science.org
Distinct Arp2/3 isocomplexes drive axonal actin ring assembly and integrity
The actin-related protein 2/3 (Arp2/3) complex is a central nucleator of branched actin filaments, essential for numerous cellular processes. Using superresolution imaging, we demonstrate that Arp2/3 ...
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MadScientist @mads100tist.bsky.social · 25/09/2026
As Gregor Samsa awoke one morning from uneasy dreams he found himself transformed in his bed into a senior postdoc
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Jorge Ferreira @jorgeferreira.bsky.social · 25/09/2026
Don´t know yet what you´ll be doing next April? Why not join us for a great meeting in Porto? Registration for Forces across scales is now open! meetings.embo.org/event/27-for...
meetings.embo.org
Forces across scales
This EMBO Workshop on Forces Across Scales will provide an integrative perspective on mechanobiology, a rapidly advancing field that examines how mechanical forces shape biological systems across mol…
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Marc Robinson-Rechavi @marcrr.bsky.social · 25/09/2026
Hill I'm ready to die on: whether for grants or articles, review by AI is not *peer review*. Review based on a 1st scan by AI without actual reading of the grant or manuscript is not peer review either.
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Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦ @dudinlab.bsky.social · 22/09/2026
Busy week for #ProtistsOnSky After some planning with Tom Battin & @nikobiota.bsky.social The #Alpine #Microbial Workshop is finally here in #Sion! We're grateful to all funders @sciencesunige.bsky.social #EPFL @embl.org & many supportive foundations & all our collaborators who made this possible.
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Giulia Paci @giuliapaci.bsky.social · 25/09/2026
Last month to apply for ECR places on our workshop on developmental robustness taking place next April. Apply and spread the word, I promise it’s going to be great!
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Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦ @dudinlab.bsky.social · 24/09/2026
How "hot" is "hot" for a cell ? Amazing work by @hbrappap.bsky.social & @oliverio.bsky.social & all authors. Makes you think a tad about how a cell can polymerize its cytoskeleton at these temperatures !
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Agathe Chaigne @agathechaigne.bsky.social · 24/09/2026
I'm super proud of this review written (mostly) by Zoé Ducarne and @myanhtruong.bsky.social about the extraordinary genomic features of the placenta. Such a crazy organ! journals.biologists.com/dev/article/...
journals.biologists.com
The curious case of the placental genome
Summary: The placenta is the only mammalian organ that harbors a cancer-like genome while remaining functional and healthy. This Review highlights its high mutational load, structural variants, aneupl...
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Levayer Lab @levayerr.bsky.social · 23/09/2026
Not every cell react the same way to caspase activation. In our recent study (led by @tomcumming.bsky.social and initiated by @avillars.bsky.social ), we tried to better understand what explains this difference and outlined a role of past caspase exposure 👇 www.nature.com/articles/s41...
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Benoit Ladoux @bladoux.bsky.social · 23/09/2026
What determines how epithelial cells divide when shape cues disappear? Our new work in @natcomms.nature.com shows that divisions follow maximal stress anisotropy — a “principal-stress rule” beyond Hertwig’s long-axis rule. Fantastic work led by @luanger.bsky.social www.nature.com/articles/s41...
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Simonetta Gribaldo @sgribaldo.bsky.social · 23/09/2026
Interested in #archaea, #methane, #cell-envelopes? New paper out @nature.com ! We discovered an enzyme that specifically cleaves the cell wall of methanogens, revealing a new chemical structure of archaeal peptidoglycan, 50 yrs after its first description www.nature.com/articles/s41... #MicroSky 🧵👇
nature.com
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André Nadler @nadlerlab.bsky.social · 23/09/2026
This my friends, this is the big one. A long time coming. Lipid Cell Biology is coming of age and even for a hot field, this is a true game changer. This dataset will keep us all busy for years to come. Congrats to everybody on this amazing crew!!! Go party!!
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H. B. Beryl Rappaport @hbrappap.bsky.social · 22/09/2026
Our description of fire amoeba, 𝘐𝘯𝘤𝘦𝘯𝘥𝘪𝘢𝘮𝘰𝘦𝘣𝘢 𝘤𝘢𝘴𝘤𝘢𝘥𝘦𝘯𝘴𝘪𝘴, is now online at Cell! Thanks @oliverio.bsky.social and amazing team for questioning the limits of eukaryotes! 🔥 www.cell.com/cell/fulltex...
cell.com
A geothermal amoeba sets a new upper temperature limit for eukaryotes
The amoeba Incendiamoeba cascadensis demonstrates that eukaryotic life can withstand temperatures beyond what was thought possible and sheds light on molecular strategies for survival in extreme heat.
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Eduardo Rocha @epcrocha.bsky.social · 22/09/2026
Great work led by @tomipou.bsky.social and @jrpenades.bsky.social with contributions of Yiqing Wang from our lab. While plasmid conduction has a very long history, there is a flood of papers coming on the combinatorics of plasmid co-integrations and excisions. Makes research fun, but not easier...
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Jean-Yves Tinevez @jytinevez.bsky.social · 22/09/2026
I'd like to introduce a piece of work we did for the paper of @ines-ssm.bsky.social and colleagues in the lab of Chiara Zurzolo in @pasteur.fr www.nature.com/articles/s41...
nature.com
Tunneling nanotubes regulate mitochondrial homeostasis between glioblastoma and astrocytes, and between tumor cells in vivo - Nature Communications
Tunneling nanotube-like (TNT) connections allow mitochondrial exchange between tumor cells and its tumor microenvironment. Here, the authors show that TNT connections mediate bidirectional mitochondri...
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Audrey Dussutour @docteur-drey.bsky.social · 22/09/2026
Plongée dans le monde fascinant de micro-organismes unicellulaires doués d’intelligence ! Avec notre tout nouveau locataire au laboratoire : Spirostomum ambiguum www.lemonde.fr/sciences/art...
lemonde.fr
Plongée dans le monde fascinant de micro-organismes unicellulaires doués d’intelligence
Une cellule. C’est ce qui suffit aux eucaryotes unicellulaires pour se nourrir, se déplacer, faire des choix, apprendre ou stocker des informations. Depuis plusieurs siècles d’études et autant de cont...
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Ali Seleit @aliseleit.bsky.social · 22/09/2026
🐟 New preprint ! 🐟 For Hippo pathway aficionados. We generated a CRISPR/Cas9 mediated single-copy endogenous Yap1-mGreenLantern fusion protein in medaka to follow Yap1 dynamics in vivo, through embryogenesis and beyond. And it is such a beautiful line ! 🧵
biorxiv.org
Spatio-temporal visualisation and manipulation of endogenous Yap1 in medaka
A key requirement to address fundamental questions in developmental biology is the ability to visualise and manipulate endogenous signalling proteins in vivo. Here we generate such an enabling experim...
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Buzz Baum @buzzbaum.bsky.social · 22/09/2026
We are looking for a research assistant! Come join the team: www.jobs.ac.uk/job/DSZ826/r...
jobs.ac.uk
Research Support Officer | Cell Biology | Dr Buzz Baum | LMB 2904 at MRC Laboratory of Molecular Biology
Start your UK & international job search for academic jobs, research jobs, science jobs and managerial jobs in leading universities and top...
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paveltomancak.bsky.social @paveltomancak.bsky.social · 21/09/2026
Some 30 years ago, I went for it. ‘Twas a good decision. Do it!
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Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦ @dudinlab.bsky.social · 21/09/2026
Must admit, ever since I was a kid, I’ve dreamt of seeing microscopy images of #protists in @lemonde.fr Today, protists are everywhere, and several images were taken by the team. And seeing #ichthyosporeans there too?! 🥹 One step closer to showcasing the beauty of the invisible microbial world. 🔬✨
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Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦ @dudinlab.bsky.social · 21/09/2026
Commuting in the opposite direction this morning. An awesome 2-week adventure with the whole lab, friends & colleagues coming from all over is just about to start in the #swiss #alps Stay tuned !
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Christophe 🔬 Leterrier @christlet.bsky.social · 19/09/2026
Here's a way to get a pure science shot on Bluesky: a custom feed that only shows the posts from people you follow that are linked to a DOI bsky.app/profile/pape...
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Cnidarian developmental mechanisms group @clytia-vlfr.bsky.social · 19/09/2026
Evidence collected by successive lab members over many years that neural cells in the Clytia larva have two origins: From 'i-cells' located in endoderm and by delamination of the gastrula ectoderm. doi.org/10.1242/dev.... @biodev-vlfr.bsky.social @annaferraioli.bsky.social
The two proposed neurogenesis pathways during Clytia larval development
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Thibaut Brunet @thibautbrunet.bsky.social · 19/09/2026
Independently of everything, this was a real missed opportunity to name it Claude Bernard
BREAKING: Anthropic has quietly set up a "wet lab" in the Bay Area as it pushes Claude to conduct real-world biology experiments. — Reuters
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PM Delaux @pierremarcdelaux.bsky.social · 19/09/2026
Et bien voilà une bonne nouvelle!
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Nick Sousanis @nsousanis.bsky.social · 18/09/2026
Italo Calvino from If On a Winter’s Night a Traveler. Relevant discussion of gen Ai from 50 years ago… “What is the reading of a text, in fact, except the recording of certain thematic recurrences, certain insistences of forms and meanings?”
Text that reads:

I asked Lotaria if she has already read some books of mine that I lent her. She said no, because here she doesn't have a computer at her disposal.
She explained to me that a suitably programmed computer can read a novel in a few minutes and record the list of all the words contained in the text, in order of fre-quency. "That way I can have an already completed reading at hand," Lotaria says, "with an incalculable saving of time. What is the reading of a text, in fact, except the recording of certain thematic recurrences, certain insistences of forms and meanings? An electronic reading supplies me with a list of the frequencies, which I have only to glance at to form an idea of the problems the book suggests to my critical study. Naturally, at the highest frequencies the list records countless articles, pronouns, particles, but I don't pay them any attention. I head straight for the words richest in meaning; they can give me a fairly precise notion of the book."
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paveltomancak.bsky.social @paveltomancak.bsky.social · 18/09/2026
In light of this growing controversy, I would like to direct attention to the stunning videos 2-31! www.nikonsmallworld.com/galleries/20...
nikonsmallworld.com
A tiny roundworm and a single-celled Dileptus explore their microscopic world | 2026 Small World in Motion Competition
Nguyen Nam Nhat - A tiny roundworm and a single-celled Dileptus explore their microscopic world
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Kirsty Wan @micromotility.bsky.social · 18/09/2026
The link states that the cilia were imaged with "diffractive super resolution microscopy" which is not a technique I have ever heard of... anyone?? Apparently based on this paper? (which at first glance does not seem as outrageous as the Nikon video) arxiv.org/abs/2512.13432
arxiv.org
Spatiotemporally decoupled super-oscillatory microscopy enables label-free reconstruction of human ciliary waveforms
Imaging native motile cilia requires label-free contrast, sub-diffraction spatial discrimination, and millisecond temporal sampling. We introduce Super-Oscillatory Label-free Inertia-free Scanning (SO...
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Alessandro De Simone @desimonelab.bsky.social · 17/09/2026
How is proliferation modulated in regeneration for tissues to reach their right size? We found that, in zebrafish scales, proliferation is shut down by a moving front of osteoblast maturation. The front's dynamics scale with tissue size, ensuring proper osteoblast amplification. tinyurl.com/5e45twx3
tinyurl.com
A moving front of osteoblast maturation scales regenerating zebrafish bone
Successful regeneration recovers lost tissues to their original form. Here, we investigate how proliferation of bone-forming osteoblasts is timely regulated to control tissue size during zebrafish sca...
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John Burns @burnsajohn.bsky.social · 17/09/2026
Took my Evo Cell Bio @ColbyCollege class out for field sampling of protists today and in the meantime grabbed a quick snap of stomata on an aquatic plant with a #foldscope. I was surprised to see it... didn't even know about structure of aquatic plants!
Small aquatic plants at Johnson pond of Colby CollegeFoldscope image of aquatic plant cells with visible stomata!
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Henry Gee 亨利·纪 @endofthepier.bsky.social · 17/09/2026
Not quite - we’re going to launch one on parenting called ‘Nature Nurture’.
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Pawel Burkhardt @pawelburkhardt.bsky.social · 16/09/2026
Lovely to see several pieces of our ctenophore work featured in this beautiful new story from @quantamagazine.org 🪼 Great piece by @mstarling.bsky.social, also featuring work by @stevehaddock.bsky.social, @arnausebe.bsky.social & @hejnol.bsky.social. www.quantamagazine.org/ctenophores-...
quantamagazine.org
Ctenophores Aren’t Just Beautiful. They’re Biological Wonders. | Quanta Magazine
Comb jellies are helping answer fundamental questions in biology, from how the earliest nervous systems evolved to how bioluminescence works.
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