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Milena Schuhmacher

@mschuhmacher.bsky.social
1.7K followers 393 following 19 posts

ELISIR group leader at EPFL working on lipids and membranes using chemical biology

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Milena Schuhmacher @mschuhmacher.bsky.social · 01/10/2026
So excited to join the Perutz! #lipidtime I will also be looking for new PhD students and postdocs soon ☺️
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Vanni Lab at UNIFR, Switzerland @labvanni.bsky.social · 30/09/2026
Please share widely (and wildly)!!! If you are a computational/AI scientist in biology and plan to apply your research to frontier biology questions across different methods and communities, you shouldn't miss this!
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Mathilda Lennartz @mathilda95.bsky.social · 30/09/2026
UPDATE!: I am absolutely stoked that the second paper of my PhD is now out in @natcellbio.nature.com :D. We combined lipid imaging, STED microscopy, and mathematical modelling in a super cool team effort to quantify lipid partitioning inside clathrin-coated pits. www.nature.com/articles/s41....
nature.com
Quantification of lipid sorting during clathrin-mediated endocytosis - Nature Cell Biology
Lennartz et al. evaluate lipid enrichment in clathrin-coated pits and observe that the differential lipid partitioning into clathrin-coated pits is largely driven by the lipid asymmetry of the plasma ...
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Giovanni D’Angelo @giodang.bsky.social · 23/09/2026
#lipidtime: It's a lipid universe. Today in Nature we publish the Lipid Brain Atlas, the first map of membrane lipid composition across the entire mouse brain, a layer of organisation that cell-type and transcript maps had left out. #lipidomics #neuroscience #BrainAtlas
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Journal of Cell Biology @jcb.org · 14/09/2026
Our #Lipid & #Membrane collection highlights work on a novel acyl-CoA binding protein, and lipid organization at the soma–germline boundary in the #Drosophila embryo, and a review on detecting and modulating membrane lipids and a new toolset for #phospholipid monitoring 👉 rupress.org/jcb/collecti...
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Journal of Cell Biology @jcb.org · 07/09/2026
The cell biologist’s guide to detecting and modulating membrane #phospholipids. A review by Worcester, @gerryhammond.bsky.social and colleagues: rupress.org/jcb/article/... 📕 From our #Lipid and #Membrane collection: rupress.org/jcb/collecti... #EMBOLipidCode
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Journal of Cell Biology @jcb.org · 06/09/2026
An advanced toolset to manipulate and monitor subcellular phosphatidylinositol 3,5-bisphosphate. From Joshua Pemberton, @jburkevic.bsky.social, Tamas Balla and colleagues: rupress.org/jcb/article/... 📕 From our #Lipid and #Membrane collection: rupress.org/jcb/collecti... #EMBOLipidCode
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Waser Group @lcsolab.bsky.social · 07/09/2026
Hiring at @LcsoLab is nearly complete for 2027, with only one position left for a PhD student or a postdoc starting in Fall 2027. Applications will be considered until September 30, 2026. More information on our website: www.epfl.ch/labs/lcso/gr...
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André Nadler @nadlerlab.bsky.social · 18/08/2026
A good teaser for our recent story on lipid-protein interactions by @cookkate.bsky.social with really kind quotes by @jeremybaskin.bsky.social (Thanks!!)
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Gesellschaft Deutscher Chemiker (GDCh) @gdch.de · 22/07/2026
Der Klaus-Grohe-Preis 2026 geht erstmals an zwei Forscher: Edward Tate (London) macht Fettmoleküle zum Werkzeug gegen Krebs, Nicolas Winssinger (Genf) baut schaltbare Wirkstoffe aus Nukleinsäuren: www.gdch.app/article/klaus-grohe-preis-2026-erstmals-an-zwei-forscher-2026-07
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Maria Bohnert Lab @bohnertlab.bsky.social · 02/07/2026
Our @jcellsci.bsky.social poster article “The nucleus-vacuole junction at a glance” is out! Big thanks to @abbybuch.bsky.social and @luskinglab.bsky.social for organizing an amazing special issue “Cell biology of the nucleus”. #ContactSites journals.biologists.com/jcs/article/...
journals.biologists.com
The nucleus–vacuole junction at a glance
Summary: The nucleus–vacuole junction is a prominent contact site linking the nuclear ER and the yeast vacuole. We highlight the physiological implications and metabolic plasticity of this unique orga...
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Jana Helsen @helsenjana.bsky.social · 16/07/2026
I am starting my lab at the University of Geneva next January! Incredibly excited to soon be joining the MOCEL department as an Asst. Professor. The lab will use evolutionary cell biology to study chromosomes, centromeres & speciation 🧬🔬🌱 Intrigued, want to join or collaborate? 🔗 helsenlab.org
helsenlab.org
Helsen lab | chromosome and centromere evolution
The Helsen lab at the University of Geneva explores how centromeres and chromosomes evolve, diversify, and function across eukaryotes. Discover our latest publications, research team, and open positio...
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Marieke Oudelaar @mariekeoudelaar.bsky.social · 07/07/2026
We are looking for someone to lead the new Facility for Protein Biochemistry & Biophysics at the MPI of Immunobiology and Epigenetics in Freiburg — please spread the word and apply if you are interested!
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canaztekin.bsky.social @canaztekin.bsky.social · 30/04/2026
🔬 Diverse species. Stem cells. Highly international team. 🐸🐭 We’re looking for a Technical Assistant to join our stem cell–based research. Interested? Apply here 👉 jobs.tue.mpg.de/jobs/276
jobs.tue.mpg.de
Online Application System - Max Planck Campus Tübingen
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Claudia Matthaeus @cmatthaeus.bsky.social · 24/04/2026
Interested in caveole and/or lipid metabolism? We have two master thesis projects available in the lab @unipotsdam.bsky.social starting September or October. For more details 👇 www.matthaeus-lab.de/post/04-2026...
matthaeus-lab.de
04/2026 Master thesis projects available
We have two exciting master thesis projects available in the lab. Please see the announcements below. Start date is flexible, but earliest September or October 2026. If you are interested, please send...
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Coskun Lipid Cellar @ ZML Dresden @lipid.bsky.social · 16/04/2026
Dear Lipid and Membrane Enthusiasts, There is only one month!! left to register and submit your abstracts for the @embo.org Workshop “Lipid Code to Life”, which will be held from September 7–11, 2026, in Dresden, Germany. Workshop program and registration page: meetings.embo.org/event/26-lip...
meetings.embo.org
Lipid Code to Life
Modern lipid biology has evolved far beyond the traditional view of lipids as simple building blocks or energy substrates. Lipids are now recognised as dynamic regulators of biological structures and…
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Marintia Nava-García @marintianava.bsky.social · 14/04/2026
Beyond proteins and DNA, #lipids are emerging as key players in nuclear biology - shaping nuclear envelope dynamics, mechanosensing, gene regulation and genome stability. Our new Perspective highlights recent advances, open questions, and future directions 👉 journals.biologists.com/jcs/article/...
journals.biologists.com
Emerging roles of lipids in nuclear function and homeostasis
Summary: Lipids are increasingly recognized as essential regulators of nuclear homeostasis, membrane dynamics, mechanotransduction and genome stability, opening new frontiers for understanding nuclear...
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Kai Johnsson @kjohnsson.bsky.social · 26/03/2026
A high-affinity split-HaloTag for live-cell protein labeling. And much more. www.nature.com/articles/s41...
nature.com
A high-affinity split-HaloTag for live-cell protein labeling
Nature Communications - Lin and colleagues present high-affinity split-HaloTag pairs for protein tagging and multiplexed labelling. This versatile system allows protein visualisation with diverse...
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Jeremy Baskin @jeremybaskin.bsky.social · 18/03/2026
I've been leading a big project at Methods in Enzymology over the past year or so: editing three back-to-back-to-back volumes of articles describing the latest advances in methods for studying lipids and membranes — thank you to the 50 #lipidtime luminaries who contributed the 51 chapters! Details 👇
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Gerry Hammond @gerryhammond.bsky.social · 05/03/2026
Beautiful desert views. Beautiful membrane biology. Join us for the #FASEB Phospholipids in Aging and Disease SRC in Arizona, July 26–30 2026. Registration is now open! So much better than a Lipid Droplets conference. Also, we're co-located with FASEB Lipid Droplets 😜
events.faseb.org
Phospholipids in Aging and Disease.
Explore breakthroughs in phospholipid research, membrane biology, and aging at this leading scientific conference.
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Emmanuelle Bayer @emmanuellebayer.bsky.social · 10/02/2026
EMBO-FEBS Lecture Course – Membranes in Organelle Biogenesis 📍 Spetses, Greece | 🗓️ 10–16 May 2026 A week with leading experts on organelle biology, membranes, lipids, and dynamics. ⏰ Deadline: 1 March 2026 🔗 Info: network.febs.org/videos/membr... 📝 Register: spetses2026.sites.uu.nl
network.febs.org
Membranes and their lipids and proteins in organelle biogenesis
The Joint FEBS/EMBO Lecture Course 'Membranes and their lipids and proteins in organelle biogenesis' will take place in Spetses Island, Greece, from 10–16 May 2026. Registration is open (deadline 1 Ma...
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@MorieLAB @morielab.bsky.social · 01/02/2026
Please REPOST (“likes” don’t help in diffusion!) and consider applying: we work in such a fantastic context, we ask so interesting questions, and we have such a collegial and best-willing atmosphere… CRBM = Happy & Good Science
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CRBM-Montpellier @crbm-montpellier.bsky.social · 30/01/2026
We are hiring!
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Pavel Barahtjan @pavelbarahtjan.bsky.social · 23/01/2026
We have several Master’s thesis projects available in the D’Angelo lab, spanning different areas of lipid biology/biochemistry. If you know someone who might be interested, we’d really appreciate you sharing this. #lipidtime www.epfl.ch/labs/dangelo...
epfl.ch
Master Projects
DANGELOLAB
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Vanni Lab at UNIFR, Switzerland @labvanni.bsky.social · 30/01/2026
Please share!!! I am looking for a postdoctoral researcher to join us. Focus will be on exciting collaborative projects on lipids and membrane biology, pushing the boundaries of in silico "reconstitutions". Previous experience with molecular dynamics simulations of biological systems a strong plus!
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Jeremy Baskin @jeremybaskin.bsky.social · 07/01/2026
Thrilled to share our latest study, led by @reikatei.bsky.social, in @natchembio.nature.com! We began by asking a simple question—how do cells know if they have too much of a lipid in a particular membrane, and how do they respond to rectify this imbalance? www.nature.com/articles/s41... More info 👇
nature.com
Membrane editing with proximity labeling reveals regulators of lipid homeostasis - Nature Chemical Biology
Coupling an optogenetic lipid-modifying enzyme with proximity labeling reveals protein networks and mechanisms regulating lipid homeostasis in the membranes of target organelles.
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Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦ @dudinlab.bsky.social · 14/01/2026
If you know of any exceptional PhD student, who is ready to become independent - you should defnietly consider this EPFL opportunity !!
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David Suter @davidsuter.bsky.social · 14/01/2026
Start your independent as an ELISIR fellow right after your PhD, in one of the most terrific places in Europe !
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Luc Reym⌬nd @lreymond.bsky.social · 05/01/2026
app.jove.com/t/69405/pero...
app.jove.com
Peroxisome Staining in Mammalian Cells Using Peroxisome-Specific Probes
Read this JoVE article on Peroxisome Staining in Mammalian Cells Using Peroxisome-Specific Probes
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Luc Reym⌬nd @lreymond.bsky.social · 05/01/2026
📄New article! Fixed cell Peroxisome imaging is now possible with Peroxi_SPY probes In a new JoVE article Triana Amen, @mschuhmacher.bsky.social and Einat Zalckvar robustly show that Peroxi_SPY stained cells can be fixed and stained by IF! Detailed protocol in the article link (first reply below⬇️)
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Bryan Dickinson @chembiobryan.bsky.social · 11/11/2025
Registration for THE chemical biology conference of 2026 is now open! EMBO ChemBio 2026 in Heidelberg DeGrado, Arikin, Picotti (Keynotes). @lmkdassama.bsky.social @brianliau.bsky.social @rhodamine110.bsky.social @benlehner.bsky.social @alitavassoli.bsky.social www.embl.org/about/info/c...
embl.org
Chemical biology 2026
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Milena Schuhmacher @mschuhmacher.bsky.social · 16/10/2025
Fantastic story! Congratulations to everyone involved!
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GBM (Gesellschaft für Biochemie und Molekularbiologie) @gbmev.bsky.social · 09/10/2025
Registration open: 77. Mosbacher Kolloquium "More than lipidic barriers - New horizons in membrane biology" from March 25-28, 2026 lnkd.in/dgsW4c3 Scientific Organizers: Britta Brügger, Robert Ernst, André Nadler, Christian Ungermann Early registration & poster abstracts until January 31, 2026
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Erdinc Sezgin @sciezgin.bsky.social · 08/09/2025
Previous preprint is now published in RSC Chemical Biology. If you are interested in plasma membrane labeling, see the paper! 👇 pubs.rsc.org/en/content/a...
pubs.rsc.org
Plasma membrane labelling efficiency, internalization and partitioning of functionalized fluorescent lipids as a function of lipid structure
Labeling the plasma membrane for advanced imaging remains a significant challenge. For time-lapse live cell imaging, probe internalization and photobleaching are major limitations affecting most membr...
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Milena Schuhmacher @mschuhmacher.bsky.social · 04/09/2025
So honored to be awarded the ERC Starting Grant! I am very grateful for this support and looking forward to more exciting #lipidtime 🥳 Also, we will have positions available next year. So stay tuned!
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Science Magazine @science.org · 19/08/2025
In the new book Labwork to Leadership, chemist Jen Heemstra offers actionable leadership advice to principal investigators. Read the #ScienceBooks Review: scim.ag/4mljVr1
Cover of Labwork to Leadership
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tafesselab.bsky.social @tafesselab.bsky.social · 12/08/2025
Have you published lipid-protein interactome data? Please let us know, we’d love to include it in the repository. The goal is to build a centralized hub for the scientific community. Huge thanks to Gaelen Guzman, a graduate student/postdoc in the lab who built it from scratch.
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André Nadler @nadlerlab.bsky.social · 21/08/2025
Many thanks Helge!
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Milena Schuhmacher @mschuhmacher.bsky.social · 12/08/2025
We are hiring! If you are looking for a postdoc position and you are interested in signaling lipids and proteomics, come join us in beautiful Switzerland! More information on www.epfl.ch/labs/gr-schu...
epfl.ch
Open positions
GR-SCHUHMACHER
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Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 26/06/2025
Novel Research in Biological Artificial Intelligence: Expressions of interest and nominations for a Max Planck Director to lead research in the field of Biological Artificial Intelligence @mpi-cbg.de and @csbdresden.bsky.social. More information: www.mpi-cbg.de/news-outreac...
mpi-cbg.de
Novel Research in Biological Artificial Intelligence
Expressions of interest and nominations for a Max Planck Director to lead research in the field of Biological Artificial Intelligence.
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Helena Klara Jambor @helenajambor.bsky.social · 18/06/2025
I gave in! After students asking for it, I now made a simple figure design checklist. To help all scientists w/o graphic skills create clear, accessible, and truthful charts! -> Out in @nature Cell Biology: rdcu.be/erwl4 #DataVisualization #PhD #SciComm Thx for review @bethcimini.bsky.social + 2
rdcu.be
A checklist for designing and improving the visualization of scientific data
Nature Cell Biology - Creating clear and engaging scientific figures is crucial to communicate complex data. In this Comment, I condense principles from design, visual perception and data...
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Spirochrome @spirochrome.com · 17/06/2025
New preprint by @kjohnsson.bsky.social lab! A new split Halotag system with higher affinity of the complements + lower background. The system works with our SiR-CA & CPY-CA halotag ligands and enables STED imaging or FLIM multiplexing. The short 14 aa tag Hpep enables easy cloning free CRISPR-KI.
schematic illustration of protein labeling using the spontaneous self-complementing peptide protein split-HaloTag system. POI: protein of interest Pairwise combination of Hpep11 (TOM20-tagged) with the other three Hpep variants 8, 9 and 10 (H2B-tagged) for FLIM multiplexing. The total fluorescence intensity composite, the two separated species and their corresponding wavelet-filtered phasor plot used for species separation are presented.
Live-cell confocal imaging of histone H2B type-2E-Hpep11 CRISPR KI cell lines after 2-hours labeling with the specified CA- ligand [100 nM]. Images were taken with optimal image acquisition parameter for each dye. Scale bar: 50 μm. (a) Confocal laser scanning microscopy (CLSM) and STED images of mitochondria in U2OS cells coexpressing cpHaloΔ3 and TOM20-Hpep, either overexpressed or endogenously tagged. Scale bar: 1 μm. Pixel intensities scaled according to reference bar. (b) Representative CLSM, STED images of the CRISPR/Cas9 KI cells expressing TOM20 tagged with intact HaloTag (upper) or Hpep11 (bottom). (c) Intensity profiles along mitochondrial tubules (red and blue lines in b). Scale bar: 2 μm. (d) Representative CLSM and STED images of endogenous Hpep11-tagged clathrin with cpHaloΔ3 coexpression. Scale bar: 10 μm (overview) and 2 μm (magnification). (e) Representative CLSM, STED
images of endogenously tagged tubulin beta 4B with Hpep11. Scale bar: 10 μm (overview) and 2 μm (magnification). (f) Intensity profiles along tubulin filaments (red and blue lines in e) Means ± s.d. of the filament diameters were calculated as full width at half maximum (FWHM) from n=20 microtubule filaments, ≥ 2 images. A slight increase in cytosolic signal was noted in cells tagged with split-HaloTagat TUBB4B, compared to cells tagged with the full-length HaloTag, which may result from the presence of unbound but labeled cpHaloΔ3. All images were acquired after labeling with CA-SiR [100 nM] for one hour.
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Martin Weigert @maweigert.bsky.social · 06/06/2025
Out today in @natmethods.nature.com : Spotiflow, our transcript localization method for imaging-based spatial transcriptomics. Led by amazing PhD student @albertdm.bsky.social, joint work w @gioelelamanno.bsky.social at EPFL / @scadsai.bsky.social www.nature.com/articles/s41... rdcu.be/epIB7
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Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦ @dudinlab.bsky.social · 10/06/2025
90% of you probably don’t need to read this. But maybe some of you are curious & 10% will feel seen. Or a little less alone. This isn’t about seeking sympathy. It’s about sharing something hard to say out loud; partly to heal, partly in case someone needs to hear it too. (1/3) tinyurl.com/DudinO
cell.com
Omaya Dudin
Interview with Omaya Dudin, who uses Ichthyosporea as models to study how and why unicellular organisms evolved multicellularity at the University of Geneva.
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Sphingolipid Biology @slbiology.bsky.social · 01/06/2025
Over 150 participants from 23 countries came to Varna, Bulgaria for the 2025 FEBS Special Meeting/13th ICC. Five days of outstanding science, networking, socializing, and community! We are grateful to all the sponsors and look forward to the next one!
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Bianca Schrul @biancaschrul.bsky.social · 14/05/2025
The abstract submission deadline for the 2nd edition of our #EMBOLipidDroplets Workshop (21-26 September 2025) is approaching. Check out the agenda with an amazing lineup of speakers and submit your abstract before 10 June 2025! @embo.org @biologists.bsky.social meetings.embo.org/event/25-lip...
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Milena Schuhmacher @mschuhmacher.bsky.social · 09/04/2025
Thank you so much for your visit Jeremy, it was fantastic to have you here in Lausanne!
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Michelle Frei @michellefrei17.bsky.social · 08/04/2025
My lab at @ethzurich.bsky.social is looking for a motivated PhD student. We develop chemical tools for advanced fluorescence microscopy 🔬 and work at the interface of synthetic chemistry ⚗️ and protein engineering 🦠. Sharing with skilled Master students appreciated. More info at tinyurl.com/2dbjk5ty
Advertisement for PhD position
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André Nadler @nadlerlab.bsky.social · 10/03/2025
Are lipids actively sorted during clathrin mediated endocytosis like proteins? @mathilda95.bsky.social addresses this key open question together with our collaborators from the Honigmann and Modes labs using a new Lipid-STED workflow. www.biorxiv.org/content/10.1...
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