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David Suter

@davidsuter.bsky.social
2.2K followers 297 following 216 posts

PI at EPFL / gene regulation / chromatin / epigenetics / genomics / stem cells / transcription factors / single molecule / protein turnover www.epfl.ch/labs/suter-lab - and 🎹 www.youtube.com/@davidsuter594 / soundcloud.com/suterd7

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Reposted by David Suter
Admirable Women @admirablewomen.bsky.social · 16/09/2026
#Music teacher, conductor & composer Nadia Boulanger is regarded as the most influential music pedagogue of the 20th century. Shattered glass ceilings by becoming the first woman to conduct the Boston Symphony Orchestra, NY Philharmonic & the Royal Philharmonic Society in London. #MusicSky🧵
A dramatic black-and-white photograph of Nadia Boulanger (September 16, 1887 – October 22, 1979) conducting the orchestra of the Royal Philharmonic Society during a rehearsal at Queen’s Hall in London. The legendary French composer, conductor, and teacher is captured in a powerful, commanding pose from a lower angle. She stands behind a conductor's music stand holding open scores, with both arms raised high against a stark, solid black background. Her face is illuminated by a sharp overhead spotlight, emphasizing her stern, intensely focused expression and clear, round eyeglasses. She wears a simple, long-sleeved dark silk or satin dress with a V-neckline, adorned with a delicate starburst pendant necklace. Her hands are expressive and deliberate: her left index finger points dramatically upward toward the ceiling, while her right hand is held slightly lower, fingers curled mid-gesture. The stark, high-contrast composition isolates her figure, creating a deeply intense, artistic, and reverent mood. This photograph captures an immense moment of historical significance, illustrating the fierce focus of one of the most influential music educators and female conductors of the 20th century.
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David Suter @davidsuter.bsky.social · 02/09/2026
Sounds very exciting - for sure my own ignorance, but I cannot help being surprised that in some fields, N=1 --> big splash. In mine, N=1 --> ...most likely an artifact.
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Erik van Nimwegen @erikvannimwegen.bsky.social · 21/08/2026
Remember this? bsky.app/profile/did:... Rigorous visualization of the structure in your high-dimensional data. Fantastic work by @dhdegroot.bsky.social With help of the reviewers of Nat Biotech it is now updated, extended an officially published here: www.nature.com/articles/s41... 1/n
nature.com
Bonsai reconstructs tree representations for distortion-free visualization and exploration of high-dimensional data - Nature Biotechnology
High-dimensional data are visualized through representation on tree structures.
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Miki Ebisuya @ebisuyamiki.bsky.social · 13/08/2026
New paper from the lab! authors.elsevier.com/sd/article/S... We find that protein degradation is broadly slower in human segmentation clock cells than in mouse cells, regardless of the degradation pathway or protein category! 1/
authors.elsevier.com
Systematic differences in protein stability underlie species-specific developmental tempo
Human embryonic development proceeds more slowly than in mice. The segmentation clock offers a tractable model for studying species-specific developme…
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David Suter @davidsuter.bsky.social · 27/06/2026
Very much enjoyed this preprint - getting closer to a quantitative understanding on how promoter/enhancer interactions drive transcriptional activity: www.biorxiv.org/content/10.6...
biorxiv.org
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David Suter @davidsuter.bsky.social · 23/06/2026
What a tour-de-force ! Makes me think that the mechanisms enhancer-mediated transcriptional activation are now truly falling into place
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David Suter @davidsuter.bsky.social · 21/06/2026
Q.E.D. 🤦‍♀️🇨🇭🤦‍♂️
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David Suter @davidsuter.bsky.social · 16/06/2026
Non-science post: join us in beautiful Cully for the Lavaux Festival www.lavauxclassic.ch ! I will play along with many other laureates of the Lavaux piano competition - concert will take place outside on the lake shore, free entrance, three hours of music, Saturday June 20, 13:00 to 16:00 🎹 🎶
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Pablo Navarro @pablonavarrolab.bsky.social · 03/06/2026
Epigenetics means different things for different people. In this workshop we will discuss two major views anchored on transcriptional memory: chromatin vs networks. Come and share with us our excitement for the topic and the magnificent place, the Andalusian Baeza. urldefense.com/v3/__https:/...
urldefense.com
Workshop Transcriptional memory in health and disease
The idea that cells remember past states to prepare their future endeavors has split into two parallel languages that rarely converse. On one side, chromatin epigenetics defines inheritance through th...
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Oded Rechavi @odedrechavi.bsky.social · 10/06/2026
"The Case for a Validity Layer in Life Science Research" - a very interesting article by Meir Maor, QED's CTO. Meir explains why biology is harder for AI than mathematics. www.qedscience.com/blog/life-sc...
qedscience.com
The case for a validity layer in life science research
When OpenAI recently announced that one of its models had disproved a long-standing conjecture in discrete geometry, the scientific community took notice...
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Austin Smith @ausmith.bsky.social · 09/06/2026
Postdoc position available now in the Smith Group lsi.exeter.ac.uk/groups/smith... to test the hypothesis that differentiation biases between human pluripotent stem cell lines may be eliminated by reversion to the naïve state. careers.exeter.ac.uk/vacancies/79...
lsi.exeter.ac.uk
Smith Group - Living Systems Institute - University of Exeter
Understanding pluripotency
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David Suter @davidsuter.bsky.social · 04/06/2026
Not only at MIT...
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Rob Klose @robklose.bsky.social · 29/05/2026
Help please! We need to do some large(ish) cell culture inhibiting E-cadherin with a monoclonal antibody. Does anyone have the DECMA-1 hybridoma cell line so we could purify our own antibody? or a similar monoclonal that would do the job. Any help greatly appreciated, just DM me. Please repost!
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David Suter @davidsuter.bsky.social · 08/05/2026
📢 New preprint alert ! www.biorxiv.org/content/10.6... Joanna Dembska developed a highly scalable image-base screening platform for protein turnover modulators in human neurons, based on our fluorescent timer system. Protein turnover is perturbed in nearly all neurodegenerative diseases ...
biorxiv.org
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MC Gambetta @mcgambetta.bsky.social · 04/05/2026
Hello all, our lab is recruiting a PhD candidate to study how 3D genome folding impacts gene regulation in development. We're located at the Center for Integrative Genomics department of the University of Lausanne, Switzerland. Please email me if interested. #PhDPosition, #PhDOpportunity
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David Suter @davidsuter.bsky.social · 01/05/2026
This thread is brilliant
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Reposted by David Suter
Anna Mazzola @annamazz.bsky.social · 01/05/2026
Some useful public speaking tips from Freud here.
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David Suter @davidsuter.bsky.social · 24/04/2026
Very nice work on histone modifications of mitotic chromosomes ! And also points at issues working with nocodazole-mediated synchronization, which still so many labs use - this work here shows how it artificially results in loss of mitotic histone acetylation. www.cell.com/molecular-ce...
cell.com
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Benjamin Towbin @betowbin.bsky.social · 08/04/2026
Join us at the LS2 #Theory #across #Biology chalk talk symposium! 12 June 2026 in Bern, CH. @lifesciswitzerland.bsky.social No movies that fail, no Mac to PC issues. Only the best ideas and exchange across biology from evolution and ecology to physics of life. meetings.ls2.ch/theory-acros...
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Sasha Gusev @sashagusevposts.bsky.social · 01/04/2026
Monthly median Received to Accepted time (days) at Nature Genetics
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Oded Rechavi @odedrechavi.bsky.social · 30/03/2026
Do we grow wiser as we age? I spent 15+ years chasing glam journals, wasting time and energy (and frustrating my team and co-authors). I don’t want to wake up at 70 and realize my life went into convincing a few editors my work was trendy enough. Enough. I’ll try to be smarter.
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David Suter @davidsuter.bsky.social · 30/03/2026
Non-science post - Any plans for Easter ? If not, come join us in Evian 🇫🇷 on 4.4. for the piano marathon ! My menu: Brahms : Rhapsodie op.79 n°1, Schumann : 2 pieces from Fantaisiestücke op. 12, Chopin : Ballade n°4 & Mazurka op.59 n°2 info 👇 marathondupiano.com www.youtube.com/watch?v=ya7M...
youtube.com
Teaser - Concert Evian
YouTube video by David Suter
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Zandrea Ambrose, Ph.D. 🦠🧬🧪🧫 @zandrea.bsky.social · 29/03/2026
The Evolution of Academia
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David Suter @davidsuter.bsky.social · 26/03/2026
Email spam in 2026 is so out of control that it feels like smashing nagging mosquitoes on a hot summer night
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David Suter @davidsuter.bsky.social · 22/03/2026
Demons - Dostoïevski
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David Suter @davidsuter.bsky.social · 20/03/2026
Very interesting work from on the role of IDRs in DNA binding specificity - in the cases studied here, the DBD plays almost no role 😮. www.science.org/doi/epdf/10....
science.org
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LCBM @lcbm-epfl.bsky.social · 18/03/2026
TFs search are governed by many parameters, what about electrostatic forces? @simsakong.bsky.social led a multi-scale study on Sox2 revealing how electrostatic interactions influence its search. In close collaboration with @davidsuter.bsky.social. Congratulations Sim 🎉 www.nature.com/articles/s41...
nature.com
Electrostatic properties of disordered regions control transcription factor search and pioneer activity - Nature Communications
This work describes how positive charge in the peptide chain flanking the DNA-binding domain of transcription factors speeds up their search on free and chromatinized DNA, helping to explain why some ...
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David Suter @davidsuter.bsky.social · 18/03/2026
How do electrostatic forces impact TF search ? In joint effort with @beatfierz.bsky.social , tour-de-force from @simsakong.bsky.social who single-handedly combined in vitro SPT on DNA & chromatin, in cellulo SPT, ChIP-seq and ATAC-seq www.nature.com/articles/s41...
nature.com
Electrostatic properties of disordered regions control transcription factor search and pioneer activity - Nature Communications
This work describes how positive charge in the peptide chain flanking the DNA-binding domain of transcription factors speeds up their search on free and chromatinized DNA, helping to explain why some ...
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David Suter @davidsuter.bsky.social · 16/03/2026
Waou ! Fabulous documentary, so much deserved !
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David Suter @davidsuter.bsky.social · 12/03/2026
Submitting to Nature Friend instead of Nature
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David Suter @davidsuter.bsky.social · 09/03/2026
How do the H2A.Z histone variant and its dedicated chromatin remodeller SRCAP regulate gene expression ? Beautiful work from @armelletollenaere.bsky.social now published @ www.nature.com/articles/s41...
nature.com
Mechanisms of gene regulation by SRCAP and H2A.Z - Nature Communications
SRCAP depletion causes rapid replacement of H2A.Z by H2A, leading to upregulation of lineage-specific transcription factors. SRCAP also prevents pioneer transcription factor binding by steric hindranc...
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Sophie G Martin @sophiemartinlab.bsky.social · 03/03/2026
You are finishing your PhD and looking to continue in science? The Martin lab @biology-unige.bsky.social has an open postdoctoral position in cell biology to study cell-cell fusion. For more information, please consult mocel.unige.ch/research-gro.... Thanks for reposting!
mocel.unige.ch
Contact/Job - Department of Molecular and Cellular Biology - UNIGE
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David Suter @davidsuter.bsky.social · 26/02/2026
Useless chart of the month 🥇
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David Suter @davidsuter.bsky.social · 24/02/2026
Beautiful and intriguing piece of work on the role of hydrophobic residues in IDRs in guiding TFs to their binding sites www.sciencedirect.com/science/arti...
sciencedirect.com
Engineering intrinsically disordered regions for guiding genome navigation
Intrinsically disordered regions (IDRs) navigate transcription factors (TFs) to their binding sites in genomes, raising the question of how IDR sequen…
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David Suter @davidsuter.bsky.social · 19/02/2026
📢 New preprint from the lab by super-talented postdoc Ludovica Vanzan www.biorxiv.org/cgi/content/... - thread 👇
biorxiv.org
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David Suter @davidsuter.bsky.social · 03/02/2026
Journal X: 👊 you have two weeks max to submit your final revisions ! > 3 weeks after submission: ms status = "submitted" 🫥
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David Suter @davidsuter.bsky.social · 02/02/2026
I miss these pieces so much...sigh...
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Denis Duboule @denisduboule.bsky.social · 15/01/2026
Many congrats to the two 2026 laureates of the Jeantet Prizes!👏💐
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David Suter @davidsuter.bsky.social · 14/01/2026
Start your independent as an ELISIR fellow right after your PhD, in one of the most terrific places in Europe !
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David Suter @davidsuter.bsky.social · 23/12/2025
And here the EPFL news actu.epfl.ch/news/how-cel...
actu.epfl.ch
How cells balance their protein levels
EPFL researchers have discovered how cells help keep their protein levels steady even when their ability to make new proteins changes. The finding could shed light on how our bodies stay resilient whe...
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David Suter @davidsuter.bsky.social · 22/12/2025
Happy holiday ❄️⛄🎅! Global protein synthesis rates can fluctuate dramatically as a function of food intake, infections, energy resources, etc. Wondering whether/how protein elimination routes adapt to these changes to maintain proteome homeostasis ? Find out here: www.cell.com/cell-systems....
cell.com
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Boo!-per Lund @cooperlund.online · 18/12/2025
Things are going great over at X, The Everything App
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David Suter @davidsuter.bsky.social · 18/12/2025
Remind me, how much money does Cell pay reviewers to deal with this ?
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Rutger Bregman @rutgerbregman.com · 16/12/2025
My first Reith Lecture is now out in video form: A Time of Monsters. On moral decay, elite cowardice, and why we need a moral revolution. Watch here 👉 youtube.com/watch?v=fUJ-... (With one tiny edit at 4:28, for those who notice such things 😉)
youtube.com
Are we living through the fall of civilisation? | The Reith Lectures 2025
YouTube video by BBC Sounds
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David Suter @davidsuter.bsky.social · 11/12/2025
📢 Open position alert: the Institute of Bioengineering of EPFL is looking for a new IBI manager ➡️ careers.epfl.ch/job/Lausanne...
careers.epfl.ch
Job Details | EPFL
Lausanne
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David Suter @davidsuter.bsky.social · 08/12/2025
Sharing a recording I just made at home, Chopin Ballade 4 - seems to me there is endless work to do on this complex piece, opinions/suggestions most welcome www.youtube.com/watch?v=gu5m...
youtube.com
Chopin, Ballade no 4 opus 52 - my recording at home
YouTube video by David Suter
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David Suter @davidsuter.bsky.social · 10/11/2025
🥳 Last shameless non-scientific promotion of 2025: thrilled to get 1st prize at the Lavaux piano competition www.lavauxclassic.ch/concours/con... Amazing experience, ca 600 hrs of work, 250 for the final alone. Here one piece I played, recorded last month at home. www.youtube.com/watch?v=wAxl...
lavauxclassic.ch
Concours de piano | Lavaux Classic
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David Suter @davidsuter.bsky.social · 28/10/2025
My my this hurts 😅
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Oded Rechavi @odedrechavi.bsky.social · 28/10/2025
Having a PhD means you can find the word “unfortunately” in an email faster that the search function
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