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Center for Systems Biology Dresden

@csbdresden.bsky.social
206 followers 85 following 4 posts

Joint center @mpi-cbg.de‬, @mpipks.bsky.social & @tudresden.bsky.social. Our mission is to develop theoretical and computational approaches to biological systems.

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Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 21/09/2026
We hosted the six weeks long summer school Dive into Research for 16 students. They explored combinatorial structures in algebraic statistics and game theory and how mathematical software can be applied to these problems. Collab with MPI for Math in Science (Leipzig). @csbdresden.bsky.social
two group photos with signatures
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Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 11/09/2026
OME-Zarr Hackathon @mpi-cbg.de @csbdresden.bsky.social brings together bioimaging community for collaborative development from Sept 7-11. @openmicroscopy.org www.mpi-cbg.de/news-outreac...
mpi-cbg.de
Hackathon at MPI-CBG for handling imaging data
OME-Zarr Hackathon brings together bioimaging community for collaborative development.
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Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 07/09/2026
New tool to score AlphaFold-predicted molecular interactions: Mihaly Badonyi @mbadonyi.bsky.social & @tothpetroczylab.bsky.social have developed Pinc, an algorithm to convert AlphaFold's uncertainty into a single number. Publication in Protein Science. onlinelibrary.wiley.com/doi/10.1002/...
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Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 04/09/2026
We are hosting the Dive into Research (DiR) workshop for 16 students (Aug 10 - Sep 18), as part of the Combinatorial Synergies initiative. Organizers: Irem Portakal & Benjamin Hollering from MPI for Mathematics in the Sciences & @aidadoesmath.bsky.social @mpi-cbg.de @csbdresden.bsky.social #DiR2026
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Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 24/08/2026
We are celebrating 25 years since opening our building in Dresden on January 22, 2001! #25yearsmpicbg www.mpi-cbg.de/news-outreac...
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Jesse Veenvliet @jesseveenvliet.bsky.social · 14/08/2026
Grateful and very honored to be awarded the @gscnoffice.bsky.social GSCN Young Investigator Award! Thanks to my fantastic team & colleagues at @mpi-cbg.de, the amazing Dresden research community (incl. @poldresden.bsky.social @csbdresden.bsky.social), and all collaborators who inspire me every day.
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Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 04/08/2026
Interview with @haharrington.bsky.social, director @mpi-cbg.de and @csbdresden.bsky.social, and @gavagesylvie.bsky.social in @euromathsoc.bsky.social magazine on their research and passions. ems.press/content/seri...
ems.press
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Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 09/07/2026
The first Discrete Laplacians workshop took place @mpi-cbg.de on June 22nd to 25th, assembling 60 participants, including 9 keynote speakers and 22 contributed speakers. www.mpi-cbg.de/news-outreac...
mpi-cbg.de
First workshop for Laplace equations
MPI-CBG hosts 60 mathematicians for event on Discrete Laplacians
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Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 18/06/2026
Otto Hahn Medal for three @mpi-cbg.de researchers: Kristin Böhlig in the group of André Nadler, Alison Kickuth in the group of Jan Brugués @poldresden.bsky.social, Giulio Zucal, from MPI-MiS in Leipzig and now mentored by Türkü Özlüm Çelik and @grill-lab.bsky.social. www.mpi-cbg.de/news-outreac...
Kristin Boehlig (middle) at the award ceremonyAlison Kickuth (middle) at the award ceremonyGiulio Zucal speaking at a podium
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Pierre Haas @lepuslapis.bsky.social · 05/05/2026
New #preprint: "Nonlinear isotropic odd elasticity" arxiv.org/abs/2605.02476 More from the #PhD work of @zhaoshh.bsky.social: revealing some of the surprising nonlinear mechanical behaviour of active, "odd" solids. @mpipks.bsky.social @mpi-cbg.de @csbdresden.bsky.social
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Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 04/05/2026
Apply now for this upcoming workshop (June 22-25, 2026) at @mpi-cbg.de and @csbdresden.bsky.social bringing together researchers from a variety of subjects to present and discuss recent advances in the theory and use of discrete Laplacians. plan.events.mpg.de/event/617/
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Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 28/04/2026
Maximilian Wiesmann from the group of @aidadoesmath.bsky.social talked on the birth of AI at today's Dresden Seniors' Academy. 😮
Talk in front of an audience.
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Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 31/03/2026
The Society for Industrial and Applied Mathematics (SIAM) announced their 2026 Class of SIAM Fellows. One of them is Heather Harrington @haharrington.bsky.social, director @mpi-cbg.de, Center for Systems Biology Dresden, and professor at @ox.ac.uk. Congratulations! 🥳 www.mpi-cbg.de/news-outreac...
mpi-cbg.de
Heather Harrington is new 2026 SIAM Fellow
Recognition for mathematicians for outstanding research and service to community
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Pierre Haas @lepuslapis.bsky.social · 30/03/2026
Now #published @prxlife.bsky.social: a great Dresden collaboration on lumen mechanics with @chandraniva.bsky.social @markusmukenhirn.bsky.social, Alf Honigmann @biotec-tud.bsky.social @poldresden.bsky.social! @mpipks.bsky.social @mpi-cbg.de @csbdresden.bsky.social
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Pierre Haas @lepuslapis.bsky.social · 17/03/2026
New #preprint: "A mechanical bifurcation constrains the evolution of cell sheet folding in the family Volvocaceae" arxiv.org/abs/2603.15171 The next chapter in the #Volvox saga: work done by Valens Tribet during his internship in my group. @mpipks.bsky.social @mpi-cbg.de @csbdresden.bsky.social
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Mihaly Badonyi @mbadonyi.bsky.social · 04/03/2026
My first manuscript in MPI colours! With @tothpetroczylab.bsky.social, we show that AlphaFold PAE-derived contact probabilities are well calibrated to the fraction of true interface contacts across experimentally determined protein dimers. www.biorxiv.org/content/10.6...
Two-panel calibration plot (two benchmark dimer datasets) comparing predicted interchain contact-probability bins (x-axis) with the observed fraction of native interfacial contacts (y-axis). Points follow the diagonal, indicating close agreement between predicted probabilities and true interface-contact fractions.
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Pierre Haas @lepuslapis.bsky.social · 03/03/2026
#proudPI moment: this afternoon, my first student, Maryam Setoudeh, successfully defended her #PhD thesis @tudresden.bsky.social. Picture of happy student and inanely grinning PI provided by @zhaoshh.bsky.social. @mpipks.bsky.social @mpi-cbg.de @csbdresden.bsky.social
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Max Planck Institute for the Physics of Complex Systems @mpipks.bsky.social · 03/03/2026
The Division of Biological Physics @mpipks.bsky.social seeks a Research Group Leader in #biophysics, #softmatter physics, or related areas. (Further particulars in the ad.) Apply by the 3rd of April 2026 at pks.mpg.de/bprgl to join us in Dresden!
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Sbalzarini Lab / MOSAIC Group @mosaicgroup.bsky.social · 25/02/2026
Our work @tudresden.bsky.social @csbdresden.bsky.social @mpi-cbg.de @scadsai.bsky.social fuses representation learning with spatial statistics @iclr-conf.bsky.social enabling #AI for spatial localization patterns: openreview.net/forum?id=09Y...
openreview.net
Spatially Informed Autoencoders for Interpretable Visual...
We introduce spatially informed variational autoencoders (SI-VAE) as self-supervised deep-learning models that use stochastic point processes to predict spatial organization patterns from images....
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Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 18/02/2026
2026 marks the 25th Anniversary of @mpi-cbg.de in Dresden. We invite all Alumni to reconnect and celebrate 25 years of science together August 24-25. Sign up, if you would like to receive further updates, formal registration will follow: www.mpi-cbg.de/25th-anniver...
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Yu Tian @yutian.bsky.social · 12/02/2026
Come and join our Discrete Laplacian workshop in Dresden, Germany 🙌! With Karel Devriendt, Otto Sumray, and Giulio Zucal, we are organising the workshop in MPI-CBG, 22-25 Jun 2026. Thanks to the support from Heather Harrington's group at CSBD, MPI! Abstract ddl: 1 Mar 2026 More details follow 🧵
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Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 06/02/2026
Giulio from the group of Türkü Özlüm Çelik talks on mathematical structures during our current coffee chalk talk series @csbdresden.bsky.social @math-mpicbg.bsky.social to promote knowledge exchange between disciplines.
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Center for Systems Biology Dresden @csbdresden.bsky.social · 28/01/2026
The spring call for the ELBE Postdoctoral Fellow Program is now open. We look forward to receiving your applications by March 13, 2026! Further information can be found here: www.csbdresden.de/join-us/jobs...
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Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 09/01/2026
Snowy day @mpi-cbg.de and @csbdresden.bsky.social. ❄️❄️❄️
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Max Planck Institute for the Physics of Complex Systems @mpipks.bsky.social · 11/12/2025
How does an elastic line buckle within a curved surface? The answer, by @zhaoshh.bsky.social and @lepuslapis.bsky.social @mpipks.bsky.social @mpi-cbg.de @csbdresden.bsky.social, has now been #published @physrevlett.bsky.social: doi.org/10.1103/63py-ph5s
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Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 28/11/2025
Watch this video about the work of the research group of @agnestoth.bsky.social @mpi-cbg.de & @csbdresden.bsky.social. Agnes and her group work on protein plasticity and evolution. For her work, Agnes recently received the Schering Young Investigator Award 2025! youtu.be/lEpvGu3J63M?...
youtu.be
Protein plasticity and evolution: The research group of Agnes Toth-Petroczy at MPI-CBG
YouTube video by MPI-CBG
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Sbalzarini Lab / MOSAIC Group @mosaicgroup.bsky.social · 05/11/2025
Modeling spatial point patterns from noisy, incomplete experimental data just got easier! Great work by @domsturm.bsky.social for sparse, noise-robust model inference of point processes 🤩 @tudresden.bsky.social @csbdresden.bsky.social @mpi-cbg.de Preprint out now: arxiv.org/abs/2510.25550
arxiv.org
Robust variable selection for spatial point processes observed with noise
We propose a method for variable selection in the intensity function of spatial point processes that combines sparsity-promoting estimation with noise-robust model selection. As high-resolution spatia...
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Heather Harrington @haharrington.bsky.social · 05/11/2025
Greeted this morning with the blackboard of math discussion— looks like algebra, topology and data— during tea yesterday @csbdresden.bsky.social @mpi-cbg.de
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Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 23/10/2025
With her research group, “Algebraic Topology and Networks in Biology,” Daniela Egas Santander joins @mpi-cbg.de and @csbdresden.bsky.social. Welcome, Daniela! 🎉 @math-mpicbg.bsky.social www.mpi-cbg.de/news-outreac...
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Max Planck Institute for the Physics of Complex Systems @mpipks.bsky.social · 16/10/2025
A new call for the ELBE Visiting faculty program is now open! No matter if you are junior or senior faculty, if you work on math/physics/computer science/ML applied to life sciences, you are welcome to submit an application to come and collaborate with the groups at CSBD! Deadline is November 30th.
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Center for Systems Biology Dresden @csbdresden.bsky.social · 08/10/2025
Welcome to @mpi-cbg.de, @mpipks.bsky.social and @csbdresden.bsky.social, Fridtjof!
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Sbalzarini Lab / MOSAIC Group @mosaicgroup.bsky.social · 01/10/2025
🤩👍🏼💪🏼 Meet #TopoSPAM - a high-performance simulation platform for biological morphogenesis with a friendly Python interface. @tudresden.bsky.social @csbdresden.bsky.social @mpi-cbg.de. Solve both continuous and discrete active mechanics! Released today: arxiv.org/abs/2509.24905
arxiv.org
TopoSPAM: Topology grounded Simulation Platform for morphogenesis and biological Active Matter
We present a topology grounded, multiscale simulation platform for morphogenesis and biological active matter. Morphogenesis and biological active matter represent keystone problems in biology with ad...
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Heather Harrington @haharrington.bsky.social · 01/10/2025
Two years today! Very grateful 🙏 @mpi-cbg.de @csbdresden.bsky.social @math-mpicbg.bsky.social
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Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 30/09/2025
Schering Young Investigator Award 2025 by the Schering Stiftung for Agnes Toth-Petroczy @tothpetroczylab.bsky.social @mpi-cbg.de @csbdresden.bsky.social. She receives the award for her work on the evolution, diversity, and function of proteins. Congratulations! 🎉 www.mpi-cbg.de/news-outreac...
mpi-cbg.de
New Perspectives on the Hidden World of Proteins
 Schering Young Investigator Award 2025 goes to Agnes Toth-Petroczy
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Sbalzarini Lab / MOSAIC Group @mosaicgroup.bsky.social · 26/09/2025
🤩🤩🤩Absolutely thrilled our work is featured in the Magazine of @maxplanck.de ! Big thanks to the writer and editor 🙏🙏🙏 Never saw our work described so well! Curious? @csbdresden.bsky.social @tudresden.bsky.social @mpi-cbg.de - PDF is freely available, article starts p.36: www.mpg.de/25430399/MPR...
mpg.de
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Pierre Haas @lepuslapis.bsky.social · 19/09/2025
Now #published @pnas.org: "A model for boundary-driven tissue morphogenesis", a great #biophysics #devbio collaboration led by @danielalber.bsky.social @zhaoshh.bsky.social: doi.org/10.1073/pnas.2505160122 @mpipks.bsky.social @mpi-cbg.de @csbdresden.bsky.social @flatironinstitute.org
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Sbalzarini Lab / MOSAIC Group @mosaicgroup.bsky.social · 12/09/2025
🙏 Very honored to speak at #BuildingBridges2025 on #AI for #Biomedicine. What an amazing lineup of panelists 🤩🤩🤩 Politics and Science working together- Germany, Lithuania, Czech Republic, Poland - together for future #AI 👍🏼 @hzdr.bsky.social @csbdresden.bsky.social
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Pierre Haas @lepuslapis.bsky.social · 08/09/2025
Another #preprint: "Elasticity and plasticity of epithelial gap closure", from the #PhD work of Maryam Setoudeh: arxiv.org/abs/2509.05110 This one required a lot of (I think) beautiful #mechanics! @mpipks.bsky.social @mpi-cbg.de @csbdresden.bsky.social
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Heather Harrington @haharrington.bsky.social · 03/09/2025
Cool paper out by mathematicians studying population dynamics with algebraic geometry @georgysch.bsky.social @mpi-cbg.de @csbdresden.bsky.social @math-mpicbg.bsky.social
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Pierre Haas @lepuslapis.bsky.social · 03/09/2025
New #preprint: "Strata of Ecological Coexistence via Grassmannians" with Türkü Özlüm Çelik, Georgy Scholten, Kexin Wang, Giulio Zucal - a great, first collaboration with #mathematics @csbdresden.bsky.social @math-mpicbg.bsky.social: arxiv.org/abs/2509.00165 @mpi-cbg.de @mpipks.bsky.social
arxiv.org
Strata of Ecological Coexistence via Grassmannians
We study the Lotka--Volterra system from the perspective of computational algebraic geometry, focusing on equilibria that are both feasible and stable. These conditions stratifies the parameter space ...
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Sbalzarini Lab / MOSAIC Group @mosaicgroup.bsky.social · 24/07/2025
#GenAI meets perception psychology for better super-resolution microscopy 🤩 Fig.1 says it all! 😎 Fantastic collaboration with @casusscience.bsky.social - work of @zuseschoolsecai.bsky.social students @csbdresden.bsky.social - out now onlinelibrary.wiley.com/doi/10.1002/...
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Sbalzarini Lab / MOSAIC Group @mosaicgroup.bsky.social · 14/07/2025
⚡️Advanced Computing ❤️ laboratory experiments ➡️ an unbeatable combination to unlock the secrets of biology! Together with the Brand lab @tudresden.bsky.social we @csbdresden.bsky.social discovered a simple mechanism how tissue geometry controls growth: journals.biologists.com/dev/article/...
journals.biologists.com
Morphogen gradients are regulated by porous media characteristics of the developing tissue
Summary: Image-based 3D modeling of pore-scale extracellular space geometries of the developing zebrafish embryo reveals that the Fgf8a morphogen gradient is regulated by the porous media characterist...
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Sbalzarini Lab / MOSAIC Group @mosaicgroup.bsky.social · 10/07/2025
Our scientific computing framework #OpenFPM now has multistage and adaptive time integrators that scale to distributed CPU clusters and GPUs! Happy supercomputing! @tudresden.bsky.social @csbdresden.bsky.social @mpi-cbg.de preprint: arxiv.org/abs/2309.05331
arxiv.org
Integrating Odeint Time Stepping into OpenFPM for Distributed and GPU Accelerated Numerical Solvers
We present a software implementation integrating the time-integration library Odeint from Boost with the OpenFPM framework for scalable scientific computing. This enables compact and scalable codes fo...
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Center for Systems Biology Dresden @csbdresden.bsky.social · 27/06/2025
We are looking for a new Max Planck Director in Biomedical #AI here at @csbdresden.bsky.social @mpi-cbg.de. Excited and looking forward!
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Max Planck Institute for the Physics of Complex Systems @mpipks.bsky.social · 17/06/2025
🐠🦠Why can’t bacteria swim like fish? At microscopic scales, physics changes — viscosity rules! Researchers at our institute study how microbes like E. coli overcome this challenge with clever strategies like run-and-tumble. Watch our new video: youtu.be/drwCRRD7CGY?...
youtu.be
Tiny swimmers
YouTube video by MPIPKS
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Pierre Haas @lepuslapis.bsky.social · 17/06/2025
Now #published @cp-cellsystems.bsky.social: "Impossible ecologies: Interaction networks and stability of coexistence in ecological communities" doi.org/10.1016/j.cels.2025.101297! With @yumeng0806.bsky.social, @szhorvat.bsky.social, Carl Modes @mpipks.bsky.social @mpi-cbg.de @csbdresden.bsky.social.
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Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 12/06/2025
Formulas of Life: article of the @maxplanck.de on the research of Ivo Sbalzarini @mosaicgroup.bsky.social. Article in German language: www.mpg.de/24841408/ki-...
mpg.de
Formeln des Lebens
Künstliche Intelligenz mit physikalischem Vorwissen soll biologische Vorgänge berechenbar machen
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Sbalzarini Lab / MOSAIC Group @mosaicgroup.bsky.social · 12/06/2025
Ivo Sbalzarini was interviewed by German science radio @detektorfm.bsky.social and explains our research @csbdresden.bsky.social @mpi-cbg.de @tudresden.bsky.social to a general audience (in German only): detektor.fm/wissen/forsc...
detektor.fm
Wie kann Künstliche Intelligenz in der Biomedizin helfen?
Biologie und Medizin sind eng verknüpft. Künstliche Intelligenz kann dabei in vielen Fragen helfen. Was ist zu beachten?
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Sbalzarini Lab / MOSAIC Group @mosaicgroup.bsky.social · 08/06/2025
🔥Just out @EGPGV’25: Parallel visualization of distributed volume data for non-convex decompositions! @csbdresden.bsky.social @tudresden.bsky.social @mpi-cbg.de And the best: code is contributed upstream 🤩 diglib.eg.org/items/3aed38...
diglib.eg.org
A Transparent and Efficient Extension of IceT for Parallel Compositing on Non-Convex Volume Domain Decompositions
The IceT library is widely used for parallel compositing but does not support non-convex volume domain decompositions. We provide a backward-compatible extension of IceT to handle non-convex domain de...
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Pierre Haas @lepuslapis.bsky.social · 05/06/2025
Now #published in Phys. Rev. Lett. as an Editors' Suggestion: "Mechanics of poking a cyst" - the first paper from the PhD work of @zhaoshh.bsky.social. journals.aps.org/prl/abstract... @mpipks.bsky.social @mpi-cbg.de @csbdresden.bsky.social
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