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Martin Weigert

@maweigert.bsky.social
1K followers 267 following 18 posts

Machine Learning for Microscopy | Prof @ TU Dresden | scholar.google.com/citations?user=Z…

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Anna Foix @afoix.bsky.social · 09/07/2026
🚨🚨🚨 DEADLINE EXTENSION ALERT! 🚨🚨🚨 Great news 🧬💻 The submission deadline for the BioImage Computing (BIC) Workshop at @eccv.bsky.social is now July 20, 2026! We can't wait to see your latest research! 🔬👩‍💻👨‍💻 🚪 Submit: openreview.net/group?id=the... 🌐 Info: www.bioimagecomputing.com
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Martin Weigert @maweigert.bsky.social · 04/06/2026
Heading to #CVPR2026 in Denver, where we'll present our highlighted poster: "MuViT: Multi-Resolution Vision Transformers for Learning Across Scales in Microscopy" enabling joint processing of local/global views. youtu.be/apFzMgmUUnM Friday 5th, 4pm Poster session 2 #602 Led by @albertdm.bsky.social
youtu.be
MuViT: Multi-Resolution Vision Transformers for Learning Across Scales in Microscopy
YouTube video by Albert Dominguez Mantes
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Jean-Yves Tinevez @jytinevez.bsky.social · 27/05/2026
The paper is now published in Current Protocols!! 🎉🥳 currentprotocols.onlinelibrary.wiley.com/doi/abs/10.1... Some personal story below 👇 , and technical details in the linked post that featured the preprint 👉
currentprotocols.onlinelibrary.wiley.com
Automated Optimization of Bacterial Tracking Pipelines With TrackMate 8
Quantitative analysis of bacterial dynamics in time-lapse microscopy requires robust tracking pipelines, yet selecting and optimizing algorithms for specific experiments remains challenging. Indeed, ...
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Loïc A. Royer 💻🔬🧪 @loicaroyer.bsky.social · 03/06/2026
Want to build some of the most advanced light-sheet microscopes in the world to watch life assemble itself cell by cell? The Royer Lab @ Biohub is hiring an Optical Engineer (Advanced Light Sheet Microscopy). 🧪🔬💻🔧 #Hardware + #Python + Advanced #Optics job-boards.greenhouse.io/biohub/jobs/...
job-boards.greenhouse.io
Optical Engineer, Advanced Light Sheet Microscopy
San Francisco, CA (Hybrid)
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Virginie Uhlmann @virginieuhlmann.bsky.social · 01/06/2026
📢📢 We are hiring a Bioimage Analyst at the BioVisionCenter! 📢📢 Join our collaboration with the Flow Cytometry Facility and contribute back to the international efforts on open standards for bioimaging data! More information here, reach out if you have any question: jobs.uzh.ch/job-vacancie...
jobs.uzh.ch
UZH: Bioimage Analyst
The University of Zurich is the largest university in Switzerland and one of the most prominent in Europe. For research purposes the Biovision Center and Flow Cytometry Facility offer services to supp...
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Ali Shaib @alishaib.bsky.social · 01/06/2026
Hello #world, meet 1,000× Expansion Microscopy. A small gel would grow to the size of an Olympic swimming pool, while amino-acid-scale distances become visible with ordinary light microscopy. Led by Helena Hu from @eboyden3.bsky.social's lab, in collab with us. Story: www.biorxiv.org/content/10.6...
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Martin Weigert @maweigert.bsky.social · 30/05/2026
Join us again for the Bioimage Computing workshop at ECCV 2026! Paper deadline July 13th 🔥
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kuba sędziński @kuba-sedzinski.bsky.social · 19/05/2026
💥 🚀 New preprint! 🎉🥳 How do hundreds of organelles organize themselves into near-perfect patterns inside a cell, without a blueprint? We dive deep into how basal bodies (BBs) self-organize in MCCs - and how actin actively tunes their dynamics into order 🍪 🧵👇 (1/17)
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paveltomancak.bsky.social @paveltomancak.bsky.social · 05/05/2026
Apply by May 20th to do research @mpi-cbg.de or @biohub.org. For example, my lab is open to your #ideas that loosely align with the theme of the #evolution of #morphogenesis. The name of the game is #freedom. Join us to develop an independent research line. I provide support, mentoring & technology
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Image Cooperative @image.coop · 16/03/2026
Hello, world! We are starting a worker cooperative to build, maintain, teach, and support open source scientific imaging software. image.coop/blog/posts/2...
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Horst Obenhaus @octoscience.bsky.social · 06/03/2026
BIG UPDATES! OCTRON now supports the new SAM3 models (alongside SAM2)! We’ve also added a global switch for Detection vs. Segmentation: Use the same annotations to train either lightweight detection or full segmentation models. Plus, we’ve added support for the new YOLO26 models. ⤵️ 1/12
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Constantin Pape @cppape.bsky.social · 05/03/2026
Looking for a PhD position at the intersection of AI, imaging, and gene therapy? Apply for this position in my lab: tinyurl.com/2a2v6tvx Part of sfb1690.uni-goettingen.de to study hearing, vision, and more. Plus, you can create pretty pictures as the one below :).
A cochlea imaged in light-sheet microscopy (right) with staining for spiral ganglion neurons (red) and inner hair cells (blue). You will develop AI-based methods to analyze these structures, for example via segmentation of the individual cells (right) that will support gene therapy development for hearing loss and a better overall understanding of the anatomy of hearing.
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Jan Funke @janfunkey.bsky.social · 05/03/2026
We opened 4 PhD positions at @humantechnopole.bsky.social together with Polimi (see 👇). My lab offers a PhD project on "Computational Morphogenesis": use state-of-the-art machine learning methods together with realistic simulations to build digital twins of developing tissue. Apply by March 26.
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Wolfgang Huber @wkhuber.bsky.social · 15/01/2026
Apply for the Ascona workshop "Statistical and AI methods for multi-modal multi-scale modeling of biological systems", 28 Jun-3 Jul 2026 on Monte Verità, Lago Maggiore at the foot of the Swiss Alps. ascona2026.sciencesconf.org
View from the hotel roomPoster session 2024, with Valentina Boeva, Constantin Ahlmann-Eltze and othersWednesday afternoon hike incl. swim in the mountain riverAnother view from the hotel room
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Albert Dominguez Mantes @albertdm.bsky.social · 02/03/2026
Very happy that MuViT, our (CVPR 2026!) work on learning across spatial scales in microscopy w transformers, is out! Check Martin's thread for a nice walkthrough :) Big thanks to my advisors @maweigert.bsky.social @gioelelamanno.bsky.social! 🖥️: github.com/weigertlab/muvit 📜: arxiv.org/abs/2602.24222
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Martin Weigert @maweigert.bsky.social · 02/03/2026
Excited to share our new paper (CVPR 2026 🚀): "MuViT: Multi-Resolution Vision Transformers for Learning Across Scales in Microscopy" which enables local predictions to use global context. Great work led by @albertdm.bsky.social & another fun collab w @gioelelamanno.bsky.social! @scadsai.bsky.social
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paveltomancak.bsky.social @paveltomancak.bsky.social · 13/12/2025
#Mastodon, the Command Center for Large-Scale Lineage-Tracing Microscopy Datasets, is finally heading for publication (well, let's see). To #cite or not to cite shall no longer be the question 🙃, because the #preprint. Software is available in every #Fiji near you. www.biorxiv.org/content/10.6...
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Nature Methods @natmethods.nature.com · 08/12/2025
Method of the Year 2025: In his Comment, @janfunkey.bsky.social discusses current challenges in connectomics, which is time-consuming and labor-intensive. He focuses on proofreading and discusses how automated models might be further developed to embrace uncertainty. www.nature.com/articles/s41...
nature.com
Uncertainty quantification for connectomics - Nature Methods
As connectomics datasets grow in size and quantity, future reconstruction methods will have to work with minimal or no human supervision. For that, we will need methods that can quantify data and mode...
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Gioele La Manno @gioelelamanno.bsky.social · 16/10/2025
🧠 The Lipid #Brain Atlas is out now! If you think #lipids are boring and membranes are all the same, prepare to be surprised. Led by @lucafusarbassini.bsky.social with Giovanni D'Angelo's lab, we mapped membrane lipids in the mouse brain at high resolution. www.biorxiv.org/cgi/content/...
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ilastik-team.bsky.social @ilastik-team.bsky.social · 09/10/2025
Segment large images without tiling artifacts: sharing our work that should have been presented at ICCV in 2 weeks - the brilliant first author Elena can’t go because of visa issues. The paper: arxiv.org/abs/2503.19545 1/🧵
Large images have to be broken into tiles both for training and inference with neural networks. The tile predictions then need to be merged to produce the final volume prediction.
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Anna Foix @afoix.bsky.social · 23/09/2025
Happy to share that ShapeEmbed has been accepted at @neuripsconf.bsky.social 🎉 SE is self-supervised framework to encode 2D contours from microscopy & natural images into a latent representation invariant to translation, scaling, rotation, reflection & point indexing 📄 arxiv.org/pdf/2507.01009 (1/N)
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kuba sędziński @kuba-sedzinski.bsky.social · 22/09/2025
🧵1/14 Preprint thread! Can we predict a cell’s fate based on its dynamics? 🔮 Our new study unveils a framework for watching development unfold in real-time, revealing how a cell's shape and movement encode info about its future fate. 🔬📄 Preprint: tinyurl.com/4shf8v4x
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Aafke Gros @aafkegros.bsky.social · 19/09/2025
I gave a talk at Blender Conference yesterday, showing how biological volumes work, and how to visualize them in Blender 😋 youtu.be/WPajSWX730o?... #bcon25
youtu.be
Microscopy Nodes: handling large biological volumes — Blender Conference 2025
YouTube video by Blender
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Ryan Savill @cryaaa.bsky.social · 12/09/2025
(1/14) I’m happy and proud to introduce: SpinePy – a framework to detect the "spine" of gastruloids and measure biological and physical signals in a local dynamic 3D coordinate system. www.biorxiv.org/content/10.1...
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Virginie M. S. Ruetten @vmsruetten.bsky.social · 08/09/2025
Thanks Misha for the shout-out! It has been a truly mind-opening journey. WHOLISTIC is one step towards whole-organism neuroscience and a true physiological observatory - with extensions on the way! I am continually amazed by what the data reveals - so much remains to be discovered and mined.
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Eugene Katrukha 🇺🇦 @ekatrukha.bsky.social · 05/09/2025
Our new preprint is about the airway epithelium microtubule network, cilia, basal body protein composition, averaging of volumetric fluorescence data, and expansion microscopy. Four years of very hard work from our very talented Emma van Grinsven. www.biorxiv.org/content/10.1... (1/N)
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Nature @nature.com · 03/09/2025
How is this possible? This ant can lay eggs of two different species, birthed by the same mother
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Jain_Akanksha_ @akanksha-jain.bsky.social · 03/09/2025
Thrilled to share 🎉 I’m starting my lab at University of Zurich, DMLS as Assistant Professor (tenure track) from Jan 2026! The Neural MorphoGenomics & Developmental Dynamics Lab will be exploring how genes + morphogenesis shape brain development with organoids, imaging & spatial genomics 🧠🔬🧬
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Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 03/09/2025
Dresden researchers @paveltomancak.bsky.social @bruvellu.bsky.social, Carl Modes, @cuencam15.bsky.social ‬ & colleagues published in @nature.com that a tissue fold in fruit fly embryos buffers mechanical stresses & may have evolved in response to mechanical forces. www.mpi-cbg.de/news-outreac...
mpi-cbg.de
Mechanical forces drive evolutionary change
A small tissue fold present in fruit fly embryos buffers mechanical stresses and may have evolved in response to mechanical forces.
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EPFL School of Computer and Communication Sciences @icepfl.bsky.social · 02/09/2025
EPFL, ETH Zurich & CSCS just released Apertus, Switzerland’s first fully open-source large language model. Trained on 15T tokens in 1,000+ languages, it’s built for transparency, responsibility & the public good. Read more: actu.epfl.ch/news/apertus...
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Giovanni D’Angelo @giodang.bsky.social · 03/09/2025
Happy to share our work on uMAIA, a framework for building metabolomic atlases from mass spectrometry imaging. With uMAIA, we mapped the lipidome of zebrafish development, uncovering spatially organized metabolic programs . www.nature.com/articles/s41... #developmentalbiology #MSI #lipidtime
nature.com
Unified mass imaging maps the lipidome of vertebrate development
Nature Methods - uMAIA is an analytical framework designed to enable the construction of metabolic atlases at high resolution using mass spectrometry imaging data.
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André Nadler @nadlerlab.bsky.social · 21/08/2025
Out today in @nature.com: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism. www.nature.com/articles/s41...
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Janelia Research Campus @hhmijanelia.bsky.social · 26/08/2025
📢We're #hiring Group Leaders! Apply to lead a lab at Janelia & advance biology using theory, computational modeling & machine learning. 🔹5-year renewable appointment 🔹Pioneer new tools & approaches 🔹Collaborate across disciplines Apply by Nov. 4👉 janelia.link/groupleader
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Kyle Harrington @kyleharrington.com · 26/08/2025
Better ML for cryo-ET starts with better benchmarks. We built a phantom cryo-ET dataset (~500 tomograms) + hosted a Kaggle challenge. The result: community models beat expert tools. Read more in the @natmethods.nature.com article that just came out: 🔗 doi.org/10.1038/s415...
doi.org
A realistic phantom dataset for benchmarking cryo-ET data annotation - Nature Methods
A standardized, realistic phantom dataset consisting of ground-truth annotations for six diverse molecular species is provided as a community resource for cryo-electron-tomography algorithm benchmarki...
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Loïc A. Royer 💻🔬🧪 @loicaroyer.bsky.social · 25/08/2025
🧬🔬🧪 🎉 Our team at @czbiohub is thrilled to share TWO companion papers out today in @NatureMethods! 📦 Ultrack — robust, scalable nD cell tracking 🌐 inTRACKtive — a beautiful, open-source web viewer for lineage exploration Let’s dive in! 👇 www.nature.com/articles/s41... www.nature.com/articles/s41...
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NordenLab @nordenlab.bsky.social · 22/08/2025
The Friday second try: After intense work, especially in the last year, this work is finally ready to be seen by the public. Led by @apramos.bsky.social and great collaboration with @carldmodes.bsky.social group especially @liormoneta.bsky.social : www.biorxiv.org/content/10.1...
biorxiv.org
The Optic cup is actively shape programmed by independently patterned apical forces
During morphogenesis, initially flat tissues often must transition into complex 3D shapes, reminiscent of shape-programmable systems in physics and engineering. One key question in developmental biolo...
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Anaïs Bailles @anaisbailles.bsky.social · 13/08/2025
Our beautiful Hydra made the cover!!! 😍😍😍 An experiment performed by Pavel Mejstrik with a HCR protocol by @giuliaserafini.bsky.social, @paveltomancak.bsky.social lab @mpi-cbg.de Actin fibers in blue, nuclei in orange.
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Nicolas Chiaruttini @nkiaru.bsky.social · 12/08/2025
A new extension! Rémy made a wrapper of @albertdm.bsky.social + @maweigert.bsky.social 's Spotiflow (2/3) forum.image.sc/t/qupath-ext...
forum.image.sc
QuPath extension Spotiflow is now available
Hello @qupath team & users, We are pleased to announce a new qupath-spotiflow-extension to handle spotiflow in QuPath 🎉 ! This extension reproduces the logic behind the qupath-extension-cellpose to ...
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paveltomancak.bsky.social @paveltomancak.bsky.social · 11/08/2025
We are today kicking off the two-week @embo.org practical course on #Lightsheet # Microscopy at @mpi-cbg.de in #Dresden. This is the fifth iteration of the course. Hashtag #LISH2025 meetings.embo.org/event/25-lsm
meetings.embo.org
Light sheet microscopy
Light sheet microscopy is a technology that enables near-isotropic imaging of large biological specimens over time. It opens new avenues to study biological processes with unprecedented imaging speed…
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Nicolas Chiaruttini @nkiaru.bsky.social · 24/07/2025
Hey, it's out! doi.org/10.1016/j.ce... Aligning Big Brains and Atlases, ABBA in short, is published in Cell Reports @cp-cellreports.bsky.social . @biancasilvalab.bsky.social's lab added an analysis pipeline on top of it (BraiAn) and did all the relevant biological work. What is it ? Short thread:
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Martin Weigert @maweigert.bsky.social · 10/07/2025
Do you like developing new AI vision methods for microscopy image analysis? You love theory & implementation? 1 week left to apply for a fully funded PhD position in our lab in Dresden 🇩🇪! Topics: object detection/tracking, multimodal models & more. DM/email for details! #PhD #AcademicJobs #GPUsgoBrr
verw.tu-dresden.de
Vacancy ID 12244
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Jain_Akanksha_ @akanksha-jain.bsky.social · 01/07/2025
Very happy to share it’s online! If you read the preprint, updates include tracking cells and tissue flow, Histo4i timecourse (69 Abs) comparing spatial patterning emergence and a new WLS KO ipsc line establishing mechanosensing via YAP-WLS/WNT caudalizes organoids www.nature.com/articles/s41...
nature.com
Morphodynamics of human early brain organoid development - Nature
Human brain morphodynamics are explored using organoids.
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AI4Life @ai4life.bsky.social · 27/06/2025
The 2nd AI4Life Challenge is live! Calling the AI & bioimaging community to tackle a key microscopy challenge: removing noise while preserving detail. 📦 Paired noisy/clean datasets 📈 Ground-truth evaluation 🧠 DL focus Build, test, compete 👉 ai4life.eurobioimaging.eu/challenge-2/
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Nature @nature.com · 24/06/2025
Nature research paper: Morphodynamics of human early brain organoid development go.nature.com/4l7fDmc
go.nature.com
Morphodynamics of human early brain organoid development - Nature
Human brain morphodynamics are explored using organoids.
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Gokul Upadhyayula @supgokul.bsky.social · 16/06/2025
Finally here! Our preprint on the MOSAIC, a multimodal adaptive optical microscope enabling non‑invasive in‑vivo imaging from molecules to organisms, is out. MOSAIC captures everything from subcellular dynamics to neural activity in live mice. www.biorxiv.org/content/10.1...
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ScaDS.AI Dresden/Leipzig @scadsai.bsky.social · 06/06/2025
Get to know Spotiflow, an AI method that improves large-scale transcript localization by combining deep learning with a novel geometric detection approach. Learn more: 👉 scads.ai/transcript-d... Find the publication in Nature Methods: 👉 www.nature.com/articles/s41...
scads.ai
AI Method Improves Transcript Detection in Microscopy Images
Spotiflow improves large-scale transcript localization by combining deep learning with a novel geometric detection approach.
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Martin Weigert @maweigert.bsky.social · 06/06/2025
If you in need of a quick walkthrough @albertdm.bsky.social has you covered:
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Nature Methods @natmethods.nature.com · 06/06/2025
A nice advance for imaging-based spatially resolved transcriptomics from the Weigert and La Manno labs. Spotiflow uses deep learning for subpixel-accurate spot detection in diverse 2D and 3D images. www.nature.com/articles/s41...
nature.com
Spotiflow: accurate and efficient spot detection for fluorescence microscopy with deep stereographic flow regression - Nature Methods
Spotiflow uses deep learning for subpixel-accurate spot detection in diverse 2D and 3D images. The improved accuracy offered by Spotiflow enables improved biological insights in both iST and live imag...
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Martin Weigert @maweigert.bsky.social · 06/06/2025
Out today in @natmethods.nature.com : Spotiflow, our transcript localization method for imaging-based spatial transcriptomics. Led by amazing PhD student @albertdm.bsky.social, joint work w @gioelelamanno.bsky.social at EPFL / @scadsai.bsky.social www.nature.com/articles/s41... rdcu.be/epIB7
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Suliana Manley @sulianamanley.bsky.social · 06/04/2025
Our latest preprint www.biorxiv.org/content/10.1..., describes Willi Stepp’s project to make smart microscopy even gentler by doing event detection in phase contrast. We developed neural networks to detect mito-LD and mito-lysosome contacts, as well as mitochondrial pre-fission constrictions.
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