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📢 Do you know any #undergraduates, #gradstudents, or early-career #postdocs looking to attend #CellBio2026? We're now accepting applications for our Travel Awards that could support their participation ✈️ ⏰ Deadline: Oct. 18 👉 rupress.org/jcb/pages/al...

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Nucleolar dynamics are determined by the ordered assembly of the #ribosome. New study from Jessica Sheu-Gruttadauria and collegues (UCSF): rupress.org/jcb/article/... #Biophysics #RNAbiology #Nucleolus

Fromme Lab @fromme-lab.bsky.social · 16/09/2026

Reposted by Journal of Cell Biology

Huge kudos to JCB. Not only was the review process super constructive, they enthusiastically embraced the underutilized #GolgiTime hashtag 😀

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Pengwei Zhao, Mengyuan Zhang, Rongbin Ding et al. develop constitutive and inducible #Golgi reporter mice that enable in vivo visualization of Golgi architecture and Golgiphagy at single-cell resolution. rupress.org/jcb/article/... #Technology #Organelles

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Dysfunction of #caveolae in muscle disease: a cell biological perspective. From Harriet P. Lo, Robert G. Parton and colleagues (The University of Queensland) rupress.org/jcb/article/... #Organelles #Development #Membrane #lipid #Disease #SkeletalMuscle

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Journal of Cell Biology @jcb.org · 15/09/2026

Avl9 defines a family of DENN domain GTPase-activating proteins. New study from Ryan C. Vignogna (@rvig.bsky.social) & J. Christopher Fromme (@fromme-lab.bsky.social) @cornelluniversity.bsky.social: rupress.org/jcb/article/... #GolgiTime #GTPases #Migration #Biochemistry #StructuralBiology #Golgi

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When push comes to shove: How chromosomes absorb spindle forces without losing grip. Geert Kops @hubrechtinstitute.bsky.social highlights new study from Vanna Tran, @dumontlabucsf.bsky.social et al. (rupress.org/jcb/article/...) in Spotlight: rupress.org/jcb/article/... #KInetochores #CellDivision

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Journal of Cell Biology @jcb.org · 15/09/2026

Pathogenic #KIF1A variants differentially disrupt axonal trafficking and impede synaptic development. New study from Jayne Aiken @aikenlab.bsky.social, Erika Holzbaur @erikaholzbaur.bsky.social and colleagues @upenn.edu: rupress.org/jcb/article/... #Cytoskeleton #Disease #Neuroscience #Trafficking

Journal of Cell Biology @jcb.org · 15/09/2026

Spatially ordered zygotic genome activation fulfills embryo quality control. New study from Wenchao Qian, Hui Chen, Hongju Lee, and Matthew C. Good @buenoscience.bsky.social @upenn.edu: rupress.org/jcb/article/... #Technology #Development #CellCycle #CellDdivision #CellSignaling

Reposted by Journal of Cell Biology

Sonya Neal @neal-lab.bsky.social · 11/09/2026

📢 Attention #undergraduates, #gradstudents, and early-career #postdocs! Apply for JCB’s Alan Hall & Norton B. Gilula Travel Awards ✈️ that support your attendance at #CellBio2026 (Dec. 12-15) in San Diego! Apply by October 18 👉 rupress.org/jcb/pages/al... @ascbiology.bsky.social

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Reposted by Journal of Cell Biology

So exciting to see our work featured by @jcb.org ! 🎉 This study brings together proteomics, zebrafish & rhomboid biology. New in the final paper: Dr. Kvido Strisovsky Rhbdl2 inhibitor beautifully phenocopied the R2 KO. So proud of Saroj and grateful to co-authors and collaborators! 💕

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Journal of Cell Biology @jcb.org · 14/09/2026

🔬 From our September cover (rupress.org/jcb/issue/22...): Maximum projection confocal images of core septin Cdc11 localization in A. pullulans cells of different shapes and sizes. From Colarusso, Wirshing and Lew: rupress.org/jcb/article/...

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Journal of Cell Biology @jcb.org · 14/09/2026

Our #Lipid & #Membrane collection highlights work on a novel acyl-CoA binding protein, and lipid organization at the soma–germline boundary in the #Drosophila embryo, and a review on detecting and modulating membrane lipids and a new toolset for #phospholipid monitoring 👉 rupress.org/jcb/collecti...

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Journal of Cell Biology @jcb.org · 11/09/2026

Gourkanti et al. @neal-lab.bsky.social show that the rhomboid protease Rhbdl2 restrains #macrophage recruitment & wound repair in #zebrafish, positioning Rhbdl2 as a potential brake on macrophage-driven repair rupress.org/jcb/article/... #Migration #motility #Immunology

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Lipid-mediated activation of BLT2 promotes membrane repair to prevent cell death. New study from Yuan Chi, Kazuko Saeki, Takehiko Yokomizo and colleagues (Juntendo University): rupress.org/jcb/article/... #Biochemistry #Membrane #lipid

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Stretching the secretory pathway: mechanical control of #Golgi export. Angelika Hausser @angelikahausser.bsky.social highlights new work by Bhaskar Naidu, Vera Lillo, Manneville, Miserey, @felixmendu.bsky.social et al. (rupress.org/jcb/article/...) in Spotlight: rupress.org/jcb/article/...

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Perspective: Harriet Lo, Robert Parton et al. provide a perspective on the role of #skeletalmuscle #caveolae, focusing on the cellular processes impaired by caveola dysfunction in muscle disease. They propose a new classification for disease-associated CAV3 variants. rupress.org/jcb/article/...

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Jessica Sheu-Gruttadauria et al. show that the material properties of the #nucleolus are shaped by the assembly state of ribosomal precursors, which tune nucleolar dynamics and morphology through their interactions with the nucleolar scaffolding protein NPM1. rupress.org/jcb/article/... #Biophysics

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Vignogna (@rvig.bsky.social) and Fromme (@fromme-lab.bsky.social) identify GAP activity in several DENN domain proteins, revealing unexpected functional diversity within this protein family. rupress.org/jcb/article/... #GolgiTime #GTPases #Migration #Biochemistry #StructuralBiology #Golgi

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GCL pruning of PIP3 establishes the soma-germline boundary. From Mariyah Saiduddin, Ruth Lehmann @remlehmann.bsky.social and colleagues: rupress.org/jcb/article/... 📕 From our #Lipid and #Membrane collection: rupress.org/jcb/collecti... #EMBOLipidCode

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PISD acts as a switch between #lipophagy and fatty acid transfer to #mitochondria. From Hanbing Xue, Xingwen Hu, Zhenni Yang, Yan G. Zhao and colleagues: rupress.org/jcb/article/... 📕 From our #Lipid and #Membrane collection: rupress.org/jcb/collecti... #EMBOLipidCode

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#Ceramide transfer protein regulates G-protein coupled phospholipase signalling in #photoreceptors. New study from Shirish Mishra, Padinjat Raghu @rpadinjat.bsky.social and colleagues @ncbsbangalore.bsky.social: rupress.org/jcb/article/... #Neuroscience #Membrane #lipid #Genetics #Drosophila

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Qian et al. @buenoscience.bsky.social determine that proper spatial patterning of zygotic genome activation is required for #embryogenesis & the existence of a surveillance system for embryo quality control exquisitely tuned to spatiotemporal ordering of genome activation rupress.org/jcb/article/...

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Spotlight: Geert Kops previews work from Tran, @dumontlabucsf.bsky.social et al. (rupress.org/jcb/article/...), which uses super resolution live imaging to show that #condensin is required for local structural organization and microtubule attachment of #kinetochores. rupress.org/jcb/article/...

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Using iPSC-derived human #neurons gene-edited to express pathogenic #KIF1A variants, @aikenlab.bsky.social, @erikaholzbaur.bsky.social et al. demonstrate that distinct alterations in KIF1A motor function disrupt synaptic development through divergent cellular mechanisms rupress.org/jcb/article/...

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#Mitochondria limit coenzyme Q export under #cholesterol biosynthetic stress. From Marjana Ndoci (@mindoci.bsky.social), Thomas Langer, Soni Deshwal (@sonideshwal.bsky.social) et al. rupress.org/jcb/article/... 📕 From our #Lipid and #Membrane collection: rupress.org/jcb/collecti... #EMBOLipidCode

Reposted by Journal of Cell Biology

Stephan Huveneers @huveneerslab.bsky.social · 08/09/2026

Are you headed to the @embo.org workshop, Lipid Code to Life #EMBOLipidCode? Meet our Deputy Editor, Andrea Marat @andreamarat.bsky.social, who will be there in person! 👉 Email Andrea: rupress.org/jcb/pages/ed... 📕 Read our new collection on #Lipid and #Membrane biology: rupress.org/jcb/collecti...

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Reposted by Journal of Cell Biology

Great feeling to return from holidays and to see our image as the cover of JCB today! Super motivating start of our academic year.

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Glucose starvation signaling via nucleus-vacuole junction remodeling controls ergosterol synthesis. From Shintaro Fujimoto and Yasushi Tamura (Yamagata University): rupress.org/jcb/article/... 📕 From our #Lipid and #Membrane collection: rupress.org/jcb/collecti... #EMBOLipidCode

Journal of Cell Biology @jcb.org · 07/09/2026

Hoi1 targets BLTP2 to ER–PM contact sites to regulate lipid homeostasis. From Samantha K. Dziurdzik, Vaishnavi Sridhar, @lizconibear.bsky.social and colleagues: rupress.org/jcb/article/... 📕 From our #Lipid and #Membrane collection: rupress.org/jcb/collecti... #EMBOLipidCode

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Journal of Cell Biology @jcb.org · 07/09/2026

On our September cover (rupress.org/jcb/issue/22...): immunofuorescence image of the anterior part of a #zebrafsh embryo showing the blood vasculature in magenta and endothelial nuclei in cyan. From Janssen et al. @huveneerslab.bsky.social: doi.org/10.1083/jcb....

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Journal of Cell Biology @jcb.org · 07/09/2026

The cell biologist’s guide to detecting and modulating membrane #phospholipids. A review by Worcester, @gerryhammond.bsky.social and colleagues: rupress.org/jcb/article/... 📕 From our #Lipid and #Membrane collection: rupress.org/jcb/collecti... #EMBOLipidCode

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Journal of Cell Biology @jcb.org · 06/09/2026

An advanced toolset to manipulate and monitor subcellular phosphatidylinositol 3,5-bisphosphate. From Joshua Pemberton, @jburkevic.bsky.social, Tamas Balla and colleagues: rupress.org/jcb/article/... 📕 From our #Lipid and #Membrane collection: rupress.org/jcb/collecti... #EMBOLipidCode

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Journal of Cell Biology @jcb.org · 05/09/2026

#Ceramide mediates cell-to-cell ER stress transmission by modulating #membrane fluidity. From Yazhen Huo, Likun Wang and colleagues (Institute of Biophysics, Beijing): rupress.org/jcb/article/... 📕 From our #Lipid and #Membrane collection: rupress.org/jcb/collecti... #EMBOLipidCode

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Reposted by Journal of Cell Biology

Felix Campelo @felixmendu.bsky.social · 04/09/2026

Many thanks @jcb.org and @angelikahausser.bsky.social for highlighting our recent findings on how the Golgi responds to mechanical forces! As nicely pinpointed out, many (I think exciting and relevant) questions remain open, so I'm looking forward to seeing how this evolves in the next few years!

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Journal of Cell Biology @jcb.org · 04/09/2026

Any1 is a #phospholipid scramblase involved in #endosome biogenesis. From Jieqiong Gao, @labvanni.bsky.social, Christian Ungermann and colleagues: rupress.org/jcb/article/... 📕 From our #Lipid and #Membrane collection: rupress.org/jcb/collecti... #EMBOLipidCode

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Spotlight: @felixmendu.bsky.social et al (rupress.org/jcb/article/...) show that the #Golgi responds to the mechanical force of cell spreading by increasing its secretory output, sustaining spreading thru a self-reinforcing feedback loop. By @angelikahausser.bsky.social: rupress.org/jcb/article/...

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Chi, Saeki, Yokomizo et al. demonstrate that 12-HHT-BLT2 signaling protects alveolar epithelial cells from pore-forming toxin-induced damage by promoting membrane repair, suggesting a new therapeutic strategy for bacterial infections. rupress.org/jcb/article/... #Biochemistry #Membrane #lipid

Lujan, Malhotra et al. @crg.eu demonstrate that TANGO2 is an acyl-CoA binding protein located in the #mitochondria lumen. rupress.org/jcb/article/... 📕 From our #Lipid and #Membrane collection: rupress.org/jcb/collecti... #EMBOLipidCode

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Journal of Cell Biology @jcb.org · 02/09/2026

Read a new collection of recent articles to accompany @embo.org workshop, Lipid Code to Life #EMBOLipidCode. Selected articles explore mechanisms underlying lipid transport, endosome biogenesis, & the maintenance of lipid homeostasis at ER–plasma membrane contact sites. rupress.org/jcb/collecti...

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“With the combined support of the editorial team and reviewers, the scientific rigor and clarity of our manuscript were substantially improved.”— Dr. Zhi Hong. JCB is your partner for peer review. Learn more: hubs.la/Q04rdtS30

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Journal of Cell Biology @jcb.org · 01/09/2026

Cell cycle–dependent translation-mediated turnover of the long noncoding RNA Malat1. New study from Leah M. Plasek-Hegde, Nadya Dimitrova and colleagues @mcdb-yale.bsky.social: rupress.org/jcb/article/... #Cancer #CellCycle #CellDivision #RNAbiology #lncRNA