Decatungstate photocatalysis is often discussed from an anion-centered perspective, treating the counterion as a passive charge-balancing species. This review highlights that counterion identity can ....

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Bioisosteric replacement is a powerful strategy for optimizing physicochemical, pharmacological, and safety properties of drug candidates. In this article, we provide a bioisosteres cheat sheet comple...

Artificial intelligence (AI) and machine learning (ML) are increasingly reshaping experimental chemistry. This review maps the challenges of synthetic organic chemistry to modern digital tools that c...

Nature Reviews Chemistry, Published online: 25 August 2026; doi:10.1038/s41570-026-00872-1A 2026 public survey suggests that organic chemistry (o-chem) remains underappreciated and misunderstood in the modern era — is it finally time to take action?

Abstract. Several studies have identified phosphorylation of α-synuclein (aSyn) at multiple tyrosine residues (Y39, Y125, Y133, and Y136) within Lewy bodie

The choice of a counterion for a charged photocatalyst has long been overlooked. In this review, we summarize recent reports on counterion effects in photocatalysis, providing readers with a comprehe...

A research group is successful, because of the teamwork. I would advise aspiring academics to pursue their passion and to be patient, “Rome wasn't built in a day”. My motto is “The best is yet to com...

We herein present a bioinspired divergent total synthesis of all five canonical sparteine and lupinine alkaloids: sparteine, α-isosparteine, β-isosparteine, lupinine, and epilupinine. Our approach emu...

The total synthesis of the atypical diterpene alkaloid thelepogine is reported. Our pathway features the asymmetric construction of a carbotricyclic intermediate that undergoes a 2,3-Wittig–Still rear...

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Energy transfer (EnT) catalysed dearomative cycloadditions of bicyclic azaarenes are largely limited to [4+2] pathways, with higher-order cycloadditions being difficult to achieve. Now, the authors ci...