T and B cell-mediated immunosurveillance of the central nervous system (CNS) can become maladaptive in multiple sclerosis (MS). Epstein-Barr virus (EBV) is a likely driver of MS, yet how exactly EBV-s...

Increased expression of EBV reactivation genes in B cells and MS risk genes targeted by the EBV protein EBNA-2 precedes MS attacks, linking EBV reactivation and genetic risk to the development of MS r...

An in vivo model that is able to recover human T cells from solid tumours can identify targets to help improve CAR T cell antitumour activity.

Nature - Presence of EB Virus Nucleic Acid Homology in a “Virus-free” Line of Burkitt Tumour Cells

Elon Musk, Donald Trump, and the “public man-made death” that they’ve caused.

Central conclusions rarely change when biomedical preprints go on to be published in journals.

Advances in technology continue to refine our understanding of CD8 T cell memory, with major implications for next-generation vaccines and therapies.

B cells are highly abundant lymphocytes and central players in humoral immunity. Although T cells are well known to support humoral responses, how B c…

A synthetic cell can now grow and divide—but it’s still far from alive

The fate of T cells is determined through the expression of a unique T cell receptor (TCR). TCR epitope specificity drives spatial localization, pheno…

In an independent evaluation, frontier large language models outperformed specialized clinical artificial intelligence tools on medical knowledge, clinician alignment and real-world clinical queries.

Advances in high-throughput sequencing, single-cell profiling, and genome engineering have transformed the study of T cell receptors (TCRs), enabling the identification and functional interrogation o...

Advances in high-throughput sequencing, single-cell profiling, and genome engineering have transformed the study of T cell receptors (TCRs), enabling the identification and functional interrogation o...

Therapeutics; Immunology; Virology

Team „FAUltier“ überzeugt bei der Asian Supercomputer Challenge mit Spitzenleistung…

We’ve documented more than 100 instances of apparent data manipulation in Thermo’s catalog

Purpose The epidemiology of suspected pediatric meningoencephalitis has changed in the era of conjugate vaccines and multiplex PCR. Updated epidemiologic data are needed to adapt diagnostic and therap...

Introduction of the RTS,S malaria vaccine in routine immunisation programmes was associated with a significant reduction in mortality in young children, averting about one in eight deaths, in areas wi...

A deep-learning method predicts T cell receptor specificity and disease-associated antigens.

Questions about the culprit virus and its route of spread remain as health officials make plans for stranded passengers

The generation of effector CD8+ T cells (TEFF) requires activation of naïve CCR7+ T cells (TN) by dendritic cells (DCs) in lymphoid tissue. How TN-DC interaction duration and signal integration are co...

Metabolic quiescence of naive-like memory T cells precedes and maintains antigen-specific T cell memory – an accessible explanation based on peer-reviewed research.

B cells are a critical adaptive immune cell type in the development of TH17 cell–mediated experimental autoimmune encephalomyelitis.

A curated database of TCRs described in cardiovascular studies - RamosImmunoCardiology/CVD_TCR_Database

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