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bioRxiv Immunology

@biorxiv-immuno.bsky.social
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 9h
Alternatively polarized neutrophils metabolically restrain macrophage-driven inflammation www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 12h
Nutrient-sensitive histone propionylation regulates T cell fate and function www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 12h
Sex hormones gate the neuronal control of dendritic cell migration and immunity www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 15h
IgG4 antibody repertoire diversity is stable over several years in health and autoimmune disease www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 18h
Cholera toxin remodels intestinal immunity and suppresses systemic metabolism www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 05/10/2026
The Lag3 KIEELE motif couples HPK1 to metabolic and functional regulation of Foxp3+ regulatory T cells www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 05/10/2026
Cytokine-mediated activation of exhausted T cells www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 05/10/2026
IgG sequencing maps systemic antibody binding to oral commensals and pathobionts in health and periodontitis www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 05/10/2026
Male and female mice achieve equivalent protection against heterologous SARS-CoV-2 infection through divergent immune mechanisms www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 05/10/2026
NAD+ modulation by nicotinamide riboside enhances CD8+ T-cell metabolic fitness and effector function during Trypanosoma cruzi infection and improves parasite control www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 05/10/2026
Early-life adversity alters the adult blood proteome primarily in female mice www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 05/10/2026
CHAIR an antigen-resolved antibody-reactome resource for healthy adult immune aging www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 05/10/2026
The helminth-derived effector protein HpBARI trimerises to selectively target membrane bound ST2 receptor www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 05/10/2026
Longitudinal linear-epitope profiling of SLE identifies novel antigens associated with disease and disease activity www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 05/10/2026
Acetylated PLIN2 coordinates the innate immune system and oxylipin synthesis on lipid droplets to propagate inflammation www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 05/10/2026
A Novel Biofilm Amyloid Ligand for Caspase-11 Drives Hyperactivation in Dendritic Cells www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 05/10/2026
Protective near-germline antibodies to malaria elicited by RTS,S/AS01E vaccination in African infants www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 05/10/2026
A synthetic PGC1α co-activator reprograms microglial immunometabolism to preserve cone function in retinal degeneration www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 02/10/2026
Folate metabolism in tumor-associated macrophages drives immunosuppressive function to promote tumor growth www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 02/10/2026
Engineered CTLA-4 targeting chimeras for targeted protein degradation and immune synapse reprogramming www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 02/10/2026
Programming primary human T cells to deliver gene editing machinery www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 02/10/2026
Veillonella dispar triggers dual-hits in the pathogenesis of autoimmune hepatitis and primary biliary cholangitis via testosterone depletion-BAFF-B cell axis and Th17 cell activation www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 02/10/2026
Humoral Immune Dysregulation Defines High-Risk Cirrhotic Ascites www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 02/10/2026
SEEKER: A genome-scale library-on-library screening platform for deciphering T cell recognition of antigen www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 01/10/2026
Chemical proteomics reveals post-translational remodeling of endosomal pathways during macrophage activation. www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 01/10/2026
A pro-inflammatory effector-memory T cell program links peripheral EBV priming to CNS autoimmunity www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 01/10/2026
Methadone Triggers Fetal Membrane Sterile Inflammation Through Innate Immune and Opioid Receptor Signaling www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 01/10/2026
HLA-A*11:01-Restricted T Cell Receptors Targeting Mutant NPM1 for Adoptive Cell Therapy in Acute Myeloid Leukemia www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 01/10/2026
Double-Negative B Cell Expansion Defines a Relapse-Prone Immunophenotype in Newly Diagnosed Giant Cell Arteritis www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 01/10/2026
CD300a Blockade attenuates renal fibrosis by enhancing macrophage efferocytosis and neutrophil MMP9 production www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 01/10/2026
Stage-Specific NF-κB RelA and IRF4 Programs Drive -Synuclein-Induced Disease-Associated Microglia Differentiation www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 01/10/2026
Immune Reconstitution and Antigenic Exposure History Shape Virus-Specific Humoral Immunity in People with HIV www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 01/10/2026
Beyond HCD: complementary fragmentation chemistries expand HLA class I immunopeptidome discovery www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 30/09/2026
ClonoDynamics enables replicate-resolved inference of longitudinal T cell receptor repertoire dynamics www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 30/09/2026
Tumor cell-intrinsic mtDNA instability drives cGAS-dependent temporal remodeling of the melanoma immune microenvironment www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 30/09/2026
CD24-dependent innate immune checkpoint targeting chimera disrupts TGF-β-driven immunosuppression to enhance anti-tumor therapy www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 30/09/2026
Distinct Longitudinal Antibody Responses Following Primary Influenza Infection or Vaccination in Infants: A Prospective Birth Cohort Study www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 30/09/2026
Sexual dimorphism in adult zebrafish marrows regulates blood cell composition and immune response www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 30/09/2026
Lysophosphatidylserine Nanoparticles Induce Oral Tolerance Independent of TIM-4 and Canonical PS Processing www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 30/09/2026
Inflammation-induced of Clec18a inhibits immune responses via Trpm7-dependent Cbl activation www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 30/09/2026
Provisional extracellular matrix signaling network regulates tumor lymphoneogenesis and response to immunotherapy www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 29/09/2026
TGFB1-Engineered Induced Mesenchymal Stromal Cells Exhibit High Immunomodulatory Potency and Durably Reprogram Synovial Macrophages in Osteoarthritis www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 29/09/2026
A loopless subdomain of transferrin binding protein B can elicit a broadly cross-reactive humoral immune response targeting variants from both encapsulated and non-typeable Haemophilus influenzae www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 29/09/2026
Distinct synovial fluid B-cell differentiation and activation profiles in rheumatoid arthritis www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 29/09/2026
Profiling of intestinal T cells reveals antigen-specific dependency on early-life programming for the generation of microbiota-reactive Tregs www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 29/09/2026
Patient-Derived Melanoma Organoids Preserve Tumor-Immune Heterogeneity and Reveal Context-Dependent Responses to Immune Checkpoint Blockade www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 29/09/2026
MHC restriction is structurally encoded by the T cell receptor germline www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 29/09/2026
HIV-1 prime-boost vaccination shapes distinct clonal trajectories and memory precursor states of Env- and Gag-specific T cells www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 29/09/2026
MicroRNA-146a Deficiency Protects NOD Mice from Autoimmune Diabetes by Enhancing c-Rel-Dependent Regulatory T Cell Function www.biorxiv.org/content/10.64898/20…
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 29/09/2026
Macrophage-derived IL-27 sustains autoreactive CD8+ cytotoxic T cells in autoimmune hepatitis www.biorxiv.org/content/10.64898/20…
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