bioRxiv Immunology @biorxiv-immuno.bsky.social · 9hAlternatively polarized neutrophils metabolically restrain macrophage-driven inflammation www.biorxiv.org/content/10.64898/20… 010
bioRxiv Immunology @biorxiv-immuno.bsky.social · 12hNutrient-sensitive histone propionylation regulates T cell fate and function www.biorxiv.org/content/10.64898/20… 010
bioRxiv Immunology @biorxiv-immuno.bsky.social · 12hSex hormones gate the neuronal control of dendritic cell migration and immunity www.biorxiv.org/content/10.64898/20… 011
bioRxiv Immunology @biorxiv-immuno.bsky.social · 15hIgG4 antibody repertoire diversity is stable over several years in health and autoimmune disease www.biorxiv.org/content/10.64898/20… 010
bioRxiv Immunology @biorxiv-immuno.bsky.social · 18hCholera toxin remodels intestinal immunity and suppresses systemic metabolism www.biorxiv.org/content/10.64898/20… 020
bioRxiv Immunology @biorxiv-immuno.bsky.social · 05/10/2026The Lag3 KIEELE motif couples HPK1 to metabolic and functional regulation of Foxp3+ regulatory T cells www.biorxiv.org/content/10.64898/20… 010
bioRxiv Immunology @biorxiv-immuno.bsky.social · 05/10/2026Cytokine-mediated activation of exhausted T cells www.biorxiv.org/content/10.64898/20… 010
bioRxiv Immunology @biorxiv-immuno.bsky.social · 05/10/2026IgG sequencing maps systemic antibody binding to oral commensals and pathobionts in health and periodontitis www.biorxiv.org/content/10.64898/20… 000
bioRxiv Immunology @biorxiv-immuno.bsky.social · 05/10/2026Male and female mice achieve equivalent protection against heterologous SARS-CoV-2 infection through divergent immune mechanisms www.biorxiv.org/content/10.64898/20… 000
bioRxiv Immunology @biorxiv-immuno.bsky.social · 05/10/2026NAD+ modulation by nicotinamide riboside enhances CD8+ T-cell metabolic fitness and effector function during Trypanosoma cruzi infection and improves parasite control www.biorxiv.org/content/10.64898/20… 000
bioRxiv Immunology @biorxiv-immuno.bsky.social · 05/10/2026Early-life adversity alters the adult blood proteome primarily in female mice www.biorxiv.org/content/10.64898/20… 000
bioRxiv Immunology @biorxiv-immuno.bsky.social · 05/10/2026CHAIR an antigen-resolved antibody-reactome resource for healthy adult immune aging www.biorxiv.org/content/10.64898/20… 011
bioRxiv Immunology @biorxiv-immuno.bsky.social · 05/10/2026The helminth-derived effector protein HpBARI trimerises to selectively target membrane bound ST2 receptor www.biorxiv.org/content/10.64898/20… 000
bioRxiv Immunology @biorxiv-immuno.bsky.social · 05/10/2026Longitudinal linear-epitope profiling of SLE identifies novel antigens associated with disease and disease activity www.biorxiv.org/content/10.64898/20… 000
bioRxiv Immunology @biorxiv-immuno.bsky.social · 05/10/2026Acetylated PLIN2 coordinates the innate immune system and oxylipin synthesis on lipid droplets to propagate inflammation www.biorxiv.org/content/10.64898/20… 000
bioRxiv Immunology @biorxiv-immuno.bsky.social · 05/10/2026A Novel Biofilm Amyloid Ligand for Caspase-11 Drives Hyperactivation in Dendritic Cells www.biorxiv.org/content/10.64898/20… 000
bioRxiv Immunology @biorxiv-immuno.bsky.social · 05/10/2026Protective near-germline antibodies to malaria elicited by RTS,S/AS01E vaccination in African infants www.biorxiv.org/content/10.64898/20… 000
bioRxiv Immunology @biorxiv-immuno.bsky.social · 05/10/2026A synthetic PGC1α co-activator reprograms microglial immunometabolism to preserve cone function in retinal degeneration www.biorxiv.org/content/10.64898/20… 000
bioRxiv Immunology @biorxiv-immuno.bsky.social · 02/10/2026Folate metabolism in tumor-associated macrophages drives immunosuppressive function to promote tumor growth www.biorxiv.org/content/10.64898/20… 011
bioRxiv Immunology @biorxiv-immuno.bsky.social · 02/10/2026Engineered CTLA-4 targeting chimeras for targeted protein degradation and immune synapse reprogramming www.biorxiv.org/content/10.64898/20… 010
bioRxiv Immunology @biorxiv-immuno.bsky.social · 02/10/2026Programming primary human T cells to deliver gene editing machinery www.biorxiv.org/content/10.64898/20… 001
bioRxiv Immunology @biorxiv-immuno.bsky.social · 02/10/2026Veillonella dispar triggers dual-hits in the pathogenesis of autoimmune hepatitis and primary biliary cholangitis via testosterone depletion-BAFF-B cell axis and Th17 cell activation www.biorxiv.org/content/10.64898/20… 000
bioRxiv Immunology @biorxiv-immuno.bsky.social · 02/10/2026Humoral Immune Dysregulation Defines High-Risk Cirrhotic Ascites www.biorxiv.org/content/10.64898/20… 000
bioRxiv Immunology @biorxiv-immuno.bsky.social · 02/10/2026SEEKER: A genome-scale library-on-library screening platform for deciphering T cell recognition of antigen www.biorxiv.org/content/10.64898/20… 011
bioRxiv Immunology @biorxiv-immuno.bsky.social · 01/10/2026Chemical proteomics reveals post-translational remodeling of endosomal pathways during macrophage activation. www.biorxiv.org/content/10.64898/20… 000
bioRxiv Immunology @biorxiv-immuno.bsky.social · 01/10/2026A pro-inflammatory effector-memory T cell program links peripheral EBV priming to CNS autoimmunity www.biorxiv.org/content/10.64898/20… 042
bioRxiv Immunology @biorxiv-immuno.bsky.social · 01/10/2026Methadone Triggers Fetal Membrane Sterile Inflammation Through Innate Immune and Opioid Receptor Signaling www.biorxiv.org/content/10.64898/20… 000
bioRxiv Immunology @biorxiv-immuno.bsky.social · 01/10/2026HLA-A*11:01-Restricted T Cell Receptors Targeting Mutant NPM1 for Adoptive Cell Therapy in Acute Myeloid Leukemia www.biorxiv.org/content/10.64898/20… 030
bioRxiv Immunology @biorxiv-immuno.bsky.social · 01/10/2026Double-Negative B Cell Expansion Defines a Relapse-Prone Immunophenotype in Newly Diagnosed Giant Cell Arteritis www.biorxiv.org/content/10.64898/20… 000
bioRxiv Immunology @biorxiv-immuno.bsky.social · 01/10/2026CD300a Blockade attenuates renal fibrosis by enhancing macrophage efferocytosis and neutrophil MMP9 production www.biorxiv.org/content/10.64898/20… 010
bioRxiv Immunology @biorxiv-immuno.bsky.social · 01/10/2026Stage-Specific NF-κB RelA and IRF4 Programs Drive -Synuclein-Induced Disease-Associated Microglia Differentiation www.biorxiv.org/content/10.64898/20… 010
bioRxiv Immunology @biorxiv-immuno.bsky.social · 01/10/2026Immune Reconstitution and Antigenic Exposure History Shape Virus-Specific Humoral Immunity in People with HIV www.biorxiv.org/content/10.64898/20… 000
bioRxiv Immunology @biorxiv-immuno.bsky.social · 01/10/2026Beyond HCD: complementary fragmentation chemistries expand HLA class I immunopeptidome discovery www.biorxiv.org/content/10.64898/20… 000
bioRxiv Immunology @biorxiv-immuno.bsky.social · 30/09/2026ClonoDynamics enables replicate-resolved inference of longitudinal T cell receptor repertoire dynamics www.biorxiv.org/content/10.64898/20… 020
bioRxiv Immunology @biorxiv-immuno.bsky.social · 30/09/2026Tumor cell-intrinsic mtDNA instability drives cGAS-dependent temporal remodeling of the melanoma immune microenvironment www.biorxiv.org/content/10.64898/20… 000
bioRxiv Immunology @biorxiv-immuno.bsky.social · 30/09/2026CD24-dependent innate immune checkpoint targeting chimera disrupts TGF-β-driven immunosuppression to enhance anti-tumor therapy www.biorxiv.org/content/10.64898/20… 000
bioRxiv Immunology @biorxiv-immuno.bsky.social · 30/09/2026Distinct Longitudinal Antibody Responses Following Primary Influenza Infection or Vaccination in Infants: A Prospective Birth Cohort Study www.biorxiv.org/content/10.64898/20… 000
bioRxiv Immunology @biorxiv-immuno.bsky.social · 30/09/2026Sexual dimorphism in adult zebrafish marrows regulates blood cell composition and immune response www.biorxiv.org/content/10.64898/20… 030
bioRxiv Immunology @biorxiv-immuno.bsky.social · 30/09/2026Lysophosphatidylserine Nanoparticles Induce Oral Tolerance Independent of TIM-4 and Canonical PS Processing www.biorxiv.org/content/10.64898/20… 000
bioRxiv Immunology @biorxiv-immuno.bsky.social · 30/09/2026Inflammation-induced of Clec18a inhibits immune responses via Trpm7-dependent Cbl activation www.biorxiv.org/content/10.64898/20… 000
bioRxiv Immunology @biorxiv-immuno.bsky.social · 30/09/2026Provisional extracellular matrix signaling network regulates tumor lymphoneogenesis and response to immunotherapy www.biorxiv.org/content/10.64898/20… 000
bioRxiv Immunology @biorxiv-immuno.bsky.social · 29/09/2026TGFB1-Engineered Induced Mesenchymal Stromal Cells Exhibit High Immunomodulatory Potency and Durably Reprogram Synovial Macrophages in Osteoarthritis www.biorxiv.org/content/10.64898/20… 000
bioRxiv Immunology @biorxiv-immuno.bsky.social · 29/09/2026A loopless subdomain of transferrin binding protein B can elicit a broadly cross-reactive humoral immune response targeting variants from both encapsulated and non-typeable Haemophilus influenzae www.biorxiv.org/content/10.64898/20… 000
bioRxiv Immunology @biorxiv-immuno.bsky.social · 29/09/2026Distinct synovial fluid B-cell differentiation and activation profiles in rheumatoid arthritis www.biorxiv.org/content/10.64898/20… 010
bioRxiv Immunology @biorxiv-immuno.bsky.social · 29/09/2026Profiling of intestinal T cells reveals antigen-specific dependency on early-life programming for the generation of microbiota-reactive Tregs www.biorxiv.org/content/10.64898/20… 000
bioRxiv Immunology @biorxiv-immuno.bsky.social · 29/09/2026Patient-Derived Melanoma Organoids Preserve Tumor-Immune Heterogeneity and Reveal Context-Dependent Responses to Immune Checkpoint Blockade www.biorxiv.org/content/10.64898/20… 000
bioRxiv Immunology @biorxiv-immuno.bsky.social · 29/09/2026MHC restriction is structurally encoded by the T cell receptor germline www.biorxiv.org/content/10.64898/20… 021
bioRxiv Immunology @biorxiv-immuno.bsky.social · 29/09/2026HIV-1 prime-boost vaccination shapes distinct clonal trajectories and memory precursor states of Env- and Gag-specific T cells www.biorxiv.org/content/10.64898/20… 001
bioRxiv Immunology @biorxiv-immuno.bsky.social · 29/09/2026MicroRNA-146a Deficiency Protects NOD Mice from Autoimmune Diabetes by Enhancing c-Rel-Dependent Regulatory T Cell Function www.biorxiv.org/content/10.64898/20… 000
bioRxiv Immunology @biorxiv-immuno.bsky.social · 29/09/2026Macrophage-derived IL-27 sustains autoreactive CD8+ cytotoxic T cells in autoimmune hepatitis www.biorxiv.org/content/10.64898/20… 000