Reposted by Marson LabGladstone Institutes @gladstoneinst.bsky.social · 13/08/2026A new screening platform uncovers gene edits that enhance CAR-T cells’ ability to infiltrate and eliminate solid tumors. @marsonlab.bsky.social @nature.com @ucsanfrancisco.bsky.social gladstone.orgNew CRISPR Screening Platform Boosts Power of Immunotherapy Against Solid TumorsA new screening platform uncovers gene edits that enhance CAR-T cells' ability to infiltrate and eliminate solid tumors. 041
Marson Lab @marsonlab.bsky.social · 13/08/2026A truly incredible first paper from Julia's lab finally out in @nature.com! Just one of many big things to come from her group. @gladstoneinst.bsky.social @ucsanfrancisco.bsky.social @parkerici.bsky.social 0113
Marson Lab @marsonlab.bsky.social · 21/04/2026My lab has been studying human genes that control infection HIV infection of CD4+ T cells for over a decade. Today we report a major milestone in Cell: www.cell.com/cell/fulltex...lnkd.inLinkedInThis link will take you to a page that’s not on LinkedIn 3195
Marson Lab @marsonlab.bsky.social · 15/12/2025Good news keeps coming! Excited to share our latest preprint expanding myeloid cell editing capabilities: Virus-like particles enable targeted gene engineering and pooled CRISPR screening in primary human myeloid cells, led by Hyuncheol Jung and Pascal Devant joint with @juliacarnevale.bsky.social 1135
Reposted by Marson LabJonathan Pritchard @jkpritch.bsky.social · 11/12/2025GWAS has been an incredible discovery tool for human genetics: it regularly identifies *causal* links from 1000s of SNPs to any given trait. But mechanistic interpretation is usually difficult. Our latest work on causal models for this is out yesterday: www.nature.com/articles/s41... A short🧵:nature.comCausal modelling of gene effects from regulators to programs to traits - NatureApproaches combining genetic association and Perturb-seq data that link genetic variants to functional programs to traits are described. 318682
Marson Lab @marsonlab.bsky.social · 10/12/2025Our latest collaboration with @jkpritch.bsky.social – led by joint post-doc Mineto Ota – is in @nature.com today: www.nature.com/articles/s41... 12110
Marson Lab @marsonlab.bsky.social · 22/10/2025Happy to share our latest paper in Nature Biotech, led by graduate student Laine Goudy, joint with Luke Gilbert at Arc, developing CRISPRon/off technology for epigenetic programming of human T cells.rdcu.beIntegrated epigenetic and genetic programming of primary human T cellsNature Biotechnology - Multiplexed editing in primary human T cells generates enhanced immune cell therapies. 181