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Marson Lab

@marsonlab.bsky.social
236 followers 33 following 29 posts

News from Dr. Alex Marson's lab UCSF & Gladstone Institutes, focusing on advances in immunology, CRISPR & genomics.

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Marson Lab @marsonlab.bsky.social · 22/09/2026
Join us! 👇
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Gladstone Institutes @gladstoneinst.bsky.social · 13/08/2026
A new screening platform uncovers gene edits that enhance CAR-T cells’ ability to infiltrate and eliminate solid tumors. @marsonlab.bsky.social @nature.com @ucsanfrancisco.bsky.social
gladstone.org
New CRISPR Screening Platform Boosts Power of Immunotherapy Against Solid Tumors
A new screening platform uncovers gene edits that enhance CAR-T cells' ability to infiltrate and eliminate solid tumors.
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Marson Lab @marsonlab.bsky.social · 13/08/2026
A truly incredible first paper from Julia's lab finally out in @nature.com! Just one of many big things to come from her group. @gladstoneinst.bsky.social @ucsanfrancisco.bsky.social @parkerici.bsky.social
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Marson Lab @marsonlab.bsky.social · 21/04/2026
My lab has been studying human genes that control infection HIV infection of CD4+ T cells for over a decade. Today we report a major milestone in Cell: www.cell.com/cell/fulltex...
lnkd.in
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Marson Lab @marsonlab.bsky.social · 15/12/2025
Good news keeps coming! Excited to share our latest preprint expanding myeloid cell editing capabilities: Virus-like particles enable targeted gene engineering and pooled CRISPR screening in primary human myeloid cells, led by Hyuncheol Jung and Pascal Devant joint with @juliacarnevale.bsky.social
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Reposted by Marson Lab
Jonathan Pritchard @jkpritch.bsky.social · 11/12/2025
GWAS has been an incredible discovery tool for human genetics: it regularly identifies *causal* links from 1000s of SNPs to any given trait. But mechanistic interpretation is usually difficult. Our latest work on causal models for this is out yesterday: www.nature.com/articles/s41... A short🧵:
nature.com
Causal modelling of gene effects from regulators to programs to traits - Nature
Approaches combining genetic association and Perturb-seq data that link genetic variants to functional programs to traits are described.
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Marson Lab @marsonlab.bsky.social · 10/12/2025
Our latest collaboration with @jkpritch.bsky.social – led by joint post-doc Mineto Ota – is in @nature.com today: www.nature.com/articles/s41...
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Marson Lab @marsonlab.bsky.social · 22/10/2025
Happy to share our latest paper in Nature Biotech, led by graduate student Laine Goudy, joint with Luke Gilbert at Arc, developing CRISPRon/off technology for epigenetic programming of human T cells.
rdcu.be
Integrated epigenetic and genetic programming of primary human T cells
Nature Biotechnology - Multiplexed editing in primary human T cells generates enhanced immune cell therapies.
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