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Schumacher Lab

@schumacher-lab.bsky.social
173 followers 155 following 23 posts

We use a technology-based approach to understand how our T cells recognize cancer. @nkinl.bsky.social | Tweets from lab members

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Schumacher Lab @schumacher-lab.bsky.social · 29/09/2026
Hi, we would like to introduce PAIR-Scan, an HLA-agnostic library-on-library screening technology that can identify reactive TCR–antigen pairs with optimal killing activity among up to ~100,000 possible candidate pairs in a single-step. 🧵(1/7) www.biorxiv.org/content/10.6...
biorxiv.org
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Schumacher Lab @schumacher-lab.bsky.social · 02/05/2025
It's not the models, it's the data! We show that a substantial proportion of a widely used TCR-pMHC database does not functionally validate, causing underestimation of performance of TCR-pMHC prediction models. www.biorxiv.org/content/10.1...
biorxiv.org
A functionally validated TCR-pMHC database for TCR specificity model development
Accurate prediction of TCR specificity forms a holy grail in immunology and large language models and computational structure predictions provide a path to achieve this. Importantly, current TCR-pMHC ...
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Reposted by Schumacher Lab
Anna Obenauf @obenaufa.bsky.social · 06/01/2025
🌟Keystone Cancer Immunotherapy conference 2025 🌟 Speaker Highlight #2 at #KSCancerImmune25: Dr. Ton N. Schumacher @nkinl.bsky.social will discuss how T cells detect tumors in “Dissecting T Cell Recognition of Cancer.” Don’t miss his cutting-edge immunology insights!
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Reposted by Schumacher Lab
Netherlands Cancer Institute @nkinl.bsky.social · 13/12/2024
🏆 Congrats to Ton Schumacher of the NKI and Oncode Institute for receiving the ESMO Award for Immuno-Oncology 2024! His work on T-cells and immunotherapy is revolutionizing cancer treatment ➡️ t.co/WHlqDB7fjF
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