Advances in technology continue to refine our understanding of CD8 T cell memory, with major implications for next-generation vaccines and therapies.

Abstract. Naïve CD8+ T-cell activation needs to overcome a signaling threshold to initiate the resulting program of T cell proliferation and differentiatio

Recent studies suggest that microbes inhabit tree bark, yet little is known about their identities, functions, and environmental roles. Here we reveal, through gene-centric and genome-resolved metagen...

CD44 expressed by fibroblastic reticular cells in secondary lymphoid organs regulates trafficking of dendritic cells, and thus has an essential role in the priming of T cells and the adaptive immune r...

Nine in 10 Australian researchers had their “ideas grant” applications rejected last year, even as Australia’s medical investment fund sits on $5 billion more than it was designed to hold.

ALT: a close up of a woman 's face in a dark room

An updated outlook (2025)

The gut microbiome impacts immunity at various levels, including response to immunotherapy. Bachem et al. find that metabolic pathways shared across different microbiota constituents, including SCFA s...