Reposted by Chlanda lab
In new study led by @bdadonaite.bsky.social, we show many influenza HAs (H5, H7, H9, H1, H2, H3) can use avian or human MHC-II to enter cells.
We then use novel combo of deep mutational scanning & cryoEM to define how H5 HA binds to avian MHC-II.
Preprint: doi.org/10.64898/202...