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Reposted by @daothilab.bsky.social

Virologie Bochum @mmv-rub.bsky.social · 13/04/2026

🚨 Bemnifosbuvir shows promise against hepatitis E virus 🚨 New study: Nucleotide analogue bemnifosbuvir inhibits HEV replication in preclinical models. 💻: gut.bmj.com/content/earl... #HEV #HepatitisE #Research #Virology #RUB #HepEHub

gut.bmj.com

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Reposted by @daothilab.bsky.social

Virologie Bochum @mmv-rub.bsky.social · 14/04/2026

🔬 New insights into hepatitis E virus replication 🔬 Study reveals HEV replication occurs in proliferative cells within the intestinal crypt. Read more: www.science.org/doi/10.1126/... #HEV #HepatitisE #Research #Virology #RUB #HepEHub

science.org

Hepatitis E virus replication is maintained in proliferative cells within the intestinal crypt

Hepatitis E virus infection of the self-renewing intestinal crypt reveals a previously unknownmechanism of viral persistence.

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Ann-Kathrin Mehnert @ak-mehnert.bsky.social · 08/10/2025

🎉 Exciting news: my PhD project @daothilab.bsky.social has been published in #PLoS Pathogens! I investigated how the #hepatitis E virus ORF2 protein counteracts antiviral responses, contributing to persistent viral replication. A huge thank you to all collaborators! 🙏🏻 🔗 share.google/WwIT43Su3KOP...

share.google

The hepatitis E virus capsid protein ORF2 counteracts cell-intrinsic antiviral responses to enable persistent replication in cell culture

Author summary Hepatitis E virus (HEV) is an important yet often underestimated pathogen. Depending on the genotype, HEV infections can progress to chronicity, but the underlying mechanisms remain poo...

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The Binder Lab (DKFZ Heidelberg) @thebinderlab.bsky.social · 09/05/2025

Second Heidelberg Interferons Symposium coming up!! If you are based in HD or Mannheim (@dkfz.bsky.social, @uniheidelberg.bsky.social, @hlsalliance.bsky.social, @embl.org,...) and interested in any facet of these incredible #cytokines, join us on 🗓️ July 10/11 🏫 Marsilius Kolleg ✍🏻 bit.ly/IFN2025

Advertising flyer for the symposium, keynote lectures by Nadine Laguette from Montepellier (Crosstalk between DNA damage response and DNA sensing), Megan Stanifer from Florida (Lambda interferon in the gut epithelium) and Alessandra Mortellaro from Milano (type I interferons in hematopoiesis), plus local keynotes by Ana Martín-Villalba, Marieke Essers and Stefan Jordan.

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bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 04/02/2025

The hepatitis E virus capsid protein ORF2 counteracts cell-intrinsic antiviral responses to enable persistence in hepatocytes www.biorxiv.org/content/10.1101/202…

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