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Jeremy Keown

@jeremykeown.bsky.social
275 followers 230 following 15 posts

Kiwi | Structural Biology | RNA viruses PI in the School of Life Sciences, University of Warwick, UK Previously Grimes lab in STRUBI, Oxford. jeremyrkeown.owlstown.net

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Reposted by Jeremy Keown
Ben Nilsson-Payant @ben-nilsson-payant.bsky.social · 05/07/2026
Very happy to celebrate the first paper from the Nilsson-Payant Lab @ki.se! We investigated inactivation methods for hantaviruses (including ANDV) and for how long they can remain infectious in the environment under different conditions! journals.plos.org/plosntds/art...
journals.plos.org
Hantavirus stability and inactivation
Author summary Hantaviruses are ubiquitous rodent viruses and contain some of the most lethal known zoonotic viruses, including Andes virus (ANDV) and Hantaan virus (HTNV), with no FDA- or EMA-approve...
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Reposted by Jeremy Keown
The Royal Society @royalsociety.org · 17/06/2026
Professor Colin Kleanthous FMedSci FRS is elected a Fellow of the Royal Society. He is a biochemist whose work has fundamentally changed our understanding of the outer membrane (OM) of Gram-negative bacteria. #RSFellows royalsociety.org/people/colin-klean…
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The Gold Lab @the-gold-lab.bsky.social · 18/05/2026
If you love phages and CryoEM, the deadline to apply for a PhD studentship in my lab is 8th June!
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Max Renner @maxrenner.bsky.social · 15/05/2026
Super happy to see the final version of our paper out now 🎉🎉🎉 www.science.org/doi/10.1126/... Proud of PhD student Rupesh @rupeshjayachandran.bsky.social and postdoc Erwan for doing really nice work on this 😊
science.org
Open and closed forms of assembled henipavirus nucleoprotein suggest structural basis of genome access
Henipavirus nucleoprotein assemblies exist in different conformations, indicating temporary release of genome for RNA synthesis.
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Lars-Anders Carlson @lacarlson.bsky.social · 14/05/2026
Just over a week left to apply to our postdoc position! Reposts appreciated.
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Thelonevirologist @thelonevirologist.bsky.social · 14/05/2026
Open and closed forms of assembled henipavirus nucleoprotein suggest structural basis of genome access www.science.org/doi/10.1126/...
science.org
Open and closed forms of assembled henipavirus nucleoprotein suggest structural basis of genome access
Henipavirus nucleoprotein assemblies exist in different conformations, indicating temporary release of genome for RNA synthesis.
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Reposted by Jeremy Keown
Simon Fromm @simonfromm.bsky.social · 11/05/2026
New preprint🧊🔬Introducing LowDoseWizard—a guided SerialEM workflow for rapid, standardised cryo-TEM setup! Setting up low-dose can be slow & daunting, especially for new users. LowDoseWizard automates optics, camera, and alignment steps from minimal input — full setup in <15 min. #cryoEM #SerialEM
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Reposted by Jeremy Keown
Max Renner @maxrenner.bsky.social · 04/05/2026
📢 We are now recruiting a PhD student in Structural and Molecular Virology in Sweden 🇸🇪 Work on RNA viruses using cryo-EM and in situ cryo-ET, with access to world-class microscopy infrastructure Perfect for candidates with backgrounds in biochem, structural bio, and virology More info ⬇️
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Jeremy Keown @jeremykeown.bsky.social · 23/04/2026
Go work with Caro, she's great and does great science.
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Reposted by Jeremy Keown
Stephen Graham's Lab @atomicvirology.bsky.social · 22/04/2026
We did a thing: Scientists find a new way coronaviruses can get into human cells www.cam.ac.uk/research/new...
cam.ac.uk
Scientists find a new way coronaviruses can get into human cells
An international team of researchers has identified an East African bat coronavirus capable of entering human cells.
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Reposted by Jeremy Keown
Séamus Holden 🔬🦠🧫 @seamusholden.bsky.social · 22/04/2026
Priority areas: - Biomedical microbiology and infectious disease #microsky - Biomedical cellular disease or immunity pathways. - Environmental biology or Environmental microbiology - Plant/crop science including phenomics, plant physiology, genetics/breeding or virology. Deadline: 31 May 2026
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Séamus Holden 🔬🦠🧫 @seamusholden.bsky.social · 22/04/2026
There's more - we also have a broad call for 6 Assistant Professors in @warwicklifesci.bsky.social www.nature.com/naturecareer...
nature.com
Assistant Professor x6 - Coventry, West Midlands (GB) job with The University of Warwick | 12858563
The School of Life Sciences (SLS) wishes to appoint six excellent and ambitious early career principal investigators
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Jeremy Keown @jeremykeown.bsky.social · 15/04/2026
Thanks to the @acmedsci.bsky.social for supporting our work investigating pathogenic bunyaviruses. acmedsci.ac.uk/more/news/ac...
acmedsci.ac.uk
Academy of Medical Sciences backs 55 early career researchers with £6.7m for discovery-driven health research
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Reposted by Jeremy Keown
Stephen Graham's Lab @atomicvirology.bsky.social · 14/04/2026
Can a single viral protein change how you think 🧠🧐? We think so! Our new preprint shows how herpes simplex virus protein pUL56 turns off neuronal electrical activity. www.biorxiv.org/cgi/content/... 🟦🧵👇
biorxiv.org
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Tom Peacock @peacockflu.bsky.social · 14/04/2026
Excited to advertise a fully funded PhD with @socialinfluenza.bsky.social investigating how influenza virus evolution differs between different avian hosts (and how this impacts pandemic potential). Joint between @pirbrightinst.bsky.social + @cvrinfo.bsky.social www.findaphd.com/phds/project...
findaphd.com
FULLY FUNDED PhD - Visualising avian influenza virus tropism and co-infection in avian hosts at University of Glasgow on FindAPhD.com
PhD Project - FULLY FUNDED PhD - Visualising avian influenza virus tropism and co-infection in avian hosts at University of Glasgow, listed on FindAPhD.com
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Health + Life Science Alliance Heidelberg Mannheim @hlsalliance.bsky.social · 08/04/2026
Meet our new #AllianceFellow Jack Whitehead! The short interview about his work in the @chlandalab.bsky.social and Mahamid lab at @embl.org can be found on our LinkedIn account. @jackwh18.bsky.social
linkedin.com
Meet our new Alliance Fellow Jack Whitehead! Q: Could you tell us a bit about the work you do? Which field do you work in and who are your PIs? A: I am a structural biologist, and my work looks at… |...
Meet our new Alliance Fellow Jack Whitehead! Q: Could you tell us a bit about the work you do? Which field do you work in and who are your PIs? A: I am a structural biologist, and my work looks at th...
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Reposted by Jeremy Keown
AJ te Velthuis @ajtevelthuis.bsky.social · 12/03/2026
Transient RNA structures play a key role in the emergence of highly pathogenic avian influenza viruses! Great to see this collaboration with Mathis Funk, Mathilde Richard, Stephen Cusack, and others in @science.org www.science.org/doi/10.1126/...
science.org
Polymerase trapping as the mechanism of H5 highly pathogenic avian influenza virus genesis
Highly pathogenic avian influenza viruses (HPAIVs) derive from H5 and H7 low pathogenic avian influenza viruses (LPAIVs). Although insertion of a furin-cleavable multibasic cleavage site (MBCS) in the...
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Reposted by Jeremy Keown
Aritz Roa-Eguiara @aritz-roa.bsky.social · 07/03/2026
🚨Preprint! Happy to share the research from my PhD “Genome delivery of a contractile tailed phage and its superinfection exclusion mechanism”. We use cryoEM to study the genome ejection of the phage T4, revealing how the tape measure protein regulates the process. www.biorxiv.org/content/10.6...
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Max Renner @maxrenner.bsky.social · 13/02/2026
Mosquitoes like Aedes aegypti spread viruses that cause major global diseases. We decided to have a closer look at a family of mosquito carbohydrate-binding proteins involved in infecting these vector species. We found some unexpected things 😁 Preprint out now 🦟🦟🦟 www.biorxiv.org/content/10.6...
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Instruct-ERIC @instruct-eric.bsky.social · 10/02/2026
Delighted to hear from Jeremy Keown of @uni-of-warwick.bsky.social, outlining their work through ISIDORe, accessing Instruct-ERIC structural biology technologies! There is still time to join us for the webinar here - instruct-eric.org/events/instr...
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Lars-Anders Carlson @lacarlson.bsky.social · 23/01/2026
I am super happy to share this paper in its final form. We used FIB milling to "dig in to" cell lines and mouse brains infected with tick-borne flaviviruses, followed by cryo-ET to study the virus replication. It's open access, so have a look! #virology #teamtomo www.nature.com/articles/s41...
nature.com
Cryo-electron tomography reveals coupled flavivirus replication, budding and maturation - Nature Communications
In this study, Dahmane et al use a method called cryo-electron tomography to uncover new details of how tick-borne flaviviruses transform cells into virus factories.
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Reposted by Jeremy Keown
Ervin Fodor @efodor.bsky.social · 24/01/2026
Cryo-EM structure reveals how influenza A virus NEP binds the viral polymerase at a regulatory hotspot, coordinating RNA synthesis and nuclear export. Fantastic collaboration with @loiccarrique.bsky.social and Jon Grimes. www.science.org/doi/10.1126/...
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Ed Hutchinson @socialinfluenza.bsky.social · 24/01/2026
Beautiful work from @efodor.bsky.social and Jonathan Grimes' labs - the first full structure of the influenza A virus NEP protein, and a clear indication that its role in viral replication is more nuanced that first thought www.science.org/doi/10.1126/...
science.org
Regulatory hotspot on the influenza A virus polymerase revealed through the structure of the NEP-polymerase complex
Structural studies reveal how influenza virus switches between making new RNA genomes and exporting them from the host nucleus.
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Reposted by Jeremy Keown
Lars-Anders Carlson @lacarlson.bsky.social · 09/01/2026
Open #postdoc fellowship in my group. Virus replication and cryo-ET. Projects can be tailored to ambitious candidates with diverse backgrounds, so don't hold back from applying! DM for more info. Deadline 8 Feb. Apply here: umustipendie.varbi.com/en/what:job/... #virus #virology #teamtomo #cryoEM
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Reposted by Jeremy Keown
AJ te Velthuis @ajtevelthuis.bsky.social · 02/01/2026
Now out in Science Advances: www.science.org/doi/10.1126/...
science.org
Febrile temperature activates the innate immune response by promoting aberrant influenza A virus RNA synthesis
Fever promotes aberrant influenza A virus RNA synthesis and innate immune activation.
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Reposted by Jeremy Keown
Lars-Anders Carlson @lacarlson.bsky.social · 01/12/2025
Very cool to see our Umeå colleague and fellow structural virologist raking in a major grant. Congrats @maxrenner.bsky.social ! www.umu.se/en/news/umea...
umu.se
Umeå researchers aim to reveal how viruses build their factories
Max Renner explore how viruses copy themselves – to help stop future outbreaks.
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Daniel Goldhill @influenzal.bsky.social · 04/11/2025
If you are looking for a PhD in the UK, please check out the LIDo program - www.lido-dtp.ac.uk/apply. If you are interested in viruses and making genetically edited salmon, please look up my icase project. International students are welcome to apply! Please reach out if you have questions.
A diagram depicting a PhD project whereby editing salmon cells or ova leads to viral resistance from ISAV.
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Reposted by Jeremy Keown
Max Renner @maxrenner.bsky.social · 03/11/2025
Our new preprint is out 🥳🥳🥳 Henipaviruses, like Nipah and Hendra, package their genomes inside helical shells built by thousands of nucleoproteins. These nucleocapsids are essential to protect the viral RNA, but how do they ever let the polymerase in to read the sequence? 👇
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Tomas Malinauskas @malinauskas.bsky.social · 29/10/2025
Jeremy is an excellent scientist and leader. Highly recommended!
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Jeremy Keown @jeremykeown.bsky.social · 24/10/2025
warwick.ac.uk/fac/cross_fa... I am advertising for a PhD position in my group. We'll be investigating how pathogenic RNA viruses replicate in the nucleus. The project will teach cryoEM/ET, virus culture, and in vitro assays. If you're interested reach out and I'd be happy to have a chat.
warwick.ac.uk
Dr Jeremy Keown
Dr Jeremy Keown
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Reposted by Jeremy Keown
Melissa Webby @melissawebby.bsky.social · 23/10/2025
Looking for a PhD? 🚀 MIBTP projects are out lots to explore! 🔬 #Bacteria • #AMR • #Interdisciplinary • FUN! My projects explore how Gram-negative bacteria build and maintain their three-layered cell envelope, using cryo-EM, fluorescence microscopy and biochemistry. warwick.ac.uk/fac/cross_fa...
warwick.ac.uk
Dr Melissa Webby
Dr Melissa Webby
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Reposted by Jeremy Keown
Thelonevirologist @thelonevirologist.bsky.social · 23/10/2025
Visualizing influenza A virus assembly by in situ cryo-electron tomography www.nature.com/articles/s41...
nature.com
Visualizing influenza A virus assembly by in situ cryo-electron tomography - Nature Communications
Influenza A virus must package eight separate genomic segments, called viral ribonucleoproteins (vRNPs). Using in situ cryo-electron tomography, the authors visualize how vRNPs are clustered on cell m...
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Jeremy Keown @jeremykeown.bsky.social · 22/10/2025
www.biorxiv.org/content/10.1... Really excited to have our work out in the world. CCHFV has a 450kDa L-Protein, about twice the size of L-Proteins from other segmented RNA viruses. We have used cryoEM and functional assays to begin to understand it this massive multifunctional protein works.
biorxiv.org
Structural and functional characterisation of the Crimean-Congo Haemorrhagic Fever Virus RNA Dependent RNA Polymerase
Crimean-Congo Haemorrhagic Fever Virus (CCHFV) is found across Africa, Asia, and the Middle East where it can cause Haemorrhagic outbreaks with high case fatality rates. Central to the viral life cycl...
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Reposted by Jeremy Keown
Lars-Anders Carlson @lacarlson.bsky.social · 22/10/2025
Postdoc opportunity in another group in my department:
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Ed Hutchinson @socialinfluenza.bsky.social · 11/10/2025
Register now for this fantastic, friendly and affordable influenza community meeting - hope to see you there! Please spread the word 😊
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Influenza Update Meetings @influenzaupdate.bsky.social · 11/10/2025
REGISTRATION NOW OPEN Influenza Update 2025 University of Warwick, 15th - 16th December warwick.ac.uk/fac/sci/med/... Registration from £50 - £120 DEADLINE: 7th November We hope you can join us there!
A banner in a Charles Rennie Mackintosh style showing and influenza virion and reading 'Influenza Update Meeting'
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craigpthomp.bsky.social @craigpthomp.bsky.social · 10/09/2025
I am very excited to share our preprint: ‘Divergent antibody-mediated population immunity to H5, H7 and H9 subtype potential pandemic influenza viruses’. The first authors are Lucas Benjamin Stolle, Jai Bolton, Rebecca Steventon & Reanna Gregory. lnkd.in/eeYmfvdE
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Antoni Wrobel @agwrobel.bsky.social · 08/09/2025
Dear scientific community, I am looking for two postdoctoral structural biologists to join my group at the Department of Biochemistry, University of Oxford. my.corehr.com/pls/uoxrecru... my.corehr.com/pls/uoxrecru...
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Jeremy Keown @jeremykeown.bsky.social · 13/08/2025
Very pleased to have our new work out where we perform a structure/function study on the bornavirus polymerase complex with fantastic coauthors. Have a read www.nature.com/articles/s41... @warwicklifesci.bsky.social @loiccarrique.bsky.social @franziskaguenl.bsky.social
nature.com
The structure of the mammalian bornavirus polymerase complex - Nature Communications
Borna disease virus 1 replicates and transcribes its negative sense RNA genome in the nucleus of infected cells. Here, the authors present the cryoEM structures of the large polymerase protein in comp...
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Jeremy Keown @jeremykeown.bsky.social · 13/12/2024
Excited to share our work describing a series of structures that allow us to propose a new model for Hantavirus genome replication by the viral L-protein. Another great experience with @loiccarrique.bsky.social @ben-nilsson-payant.bsky.social @efodor.bsky.social Jon Grimes. doi.org/10.1371/jour...
doi.org
Structural characterization of the full-length Hantaan virus polymerase
Author summary Hantaviruses are widely distributed viruses that can undergo zoonosis where they cause severe disease in humans. Old World hantaviruses, found predominantly in Asia and Europe, can caus...
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