Reposted by Freddy FrischknechtFever: Global Histories of (a) Disease @feverprojecthd.bsky.social · 16/06/2026Deadline extended! Applications open until 1 July 2026! 045
Reposted by Freddy FrischknechtFever: Global Histories of (a) Disease @feverprojecthd.bsky.social · 21/05/2026Feel the heat? Join us in Heidelberg for an interdisciplinary summer school on FEVER. Stefanie Gänger, Ulrich Schwarz and Freddy Frischknecht welcome 30 participants and speakers incl. science journalist Kai Kupferschmidt to our Institute of Advanced Studies. Info & registration: lnkd.in/d7Yt5tf9 033
Freddy Frischknecht @freddyfrischknecht.bsky.social · 30/03/2026And teaching does make a difference: Just received the news from Pedro, that @mblbop.bsky.social 2024 fellow Linda obtained a postdoctoral fellowship to continue her career @gwu1821.bsky.social. That follows from a student who admitted this noon to join my lab because he listen to one of my talks. 051
Reposted by Freddy FrischknechtInstitut Pasteur Education @pasteuredu.bsky.social · 27/02/2026✨ One year on, we honor Spencer Shorte. On Jan 28, 2026, Institut Pasteur paid tribute to a visionary scientist and human leader. His legacy lives on through the PPU–Research & Technology track, uniting research & innovation as he envisioned. Inspiring future generations. 083
Freddy Frischknecht @freddyfrischknecht.bsky.social · 30/01/2026Screw it. It's weekend. My daughters new song: open.spotify.com/intl-de/trac... placed just below mighty Bruce Springsteens Streets of Minneapolis on the German Friday music stream list. 290
Reposted by Freddy FrischknechtUlrich Schwarz @ulrichschwarz.bsky.social · 23/01/2026(1/2) Our work with @freddyfrischknecht.bsky.social on the chirality of malaria parasites has found its home in the January issue of @natphys.nature.com: www.nature.com/articles/s41... Moreover, we are very happy that it comes with a news and views article 👍❤️😀nature.comChirality of malaria parasites determines their motion patterns - Nature PhysicsMalaria parasites move on helical trajectories when infecting their hosts. Now it is shown that they use right-handed chirality to control their motion patterns, and that this chirality is linked to t... 1179
Freddy Frischknecht @freddyfrischknecht.bsky.social · 01/01/2026Happy New Year from Heidelberg and looking forward to SingMalNet in Singapore in February, BioMalPar in sunny Heidelberg in May and other adventures. 0111
Freddy Frischknecht @freddyfrischknecht.bsky.social · 17/12/2025This might well become your best summer experience 061
Freddy Frischknecht @freddyfrischknecht.bsky.social · 04/12/2025Join us (again) for another fantastic BioMalPar meeting @embl.org and also a great pre-meeting @ciid-heidelberg.bsky.social 0104
Reposted by Freddy FrischknechtUlrich Schwarz @ulrichschwarz.bsky.social · 24/11/2025📢 Paper alert 📢 Chirality is known to be important for the movement of microorganisms and active matter. In our new paper out today in @natphys.nature.com, we show that chirality is used by malaria parasites to control their motion patterns: doi.org/10.1038/s415... Here comes a 🧵 ... (1/9) 18233
Reposted by Freddy FrischknechtJournal of Cell Science @jcellsci.bsky.social · 21/11/2025Mole's Comedia III. Purgatorio. Canto I–XXIV. journals.biologists.com/jcs/article/... 022
Freddy Frischknecht @freddyfrischknecht.bsky.social · 11/11/2025Beautiful beasts (2): Thanks Ian for allowing us to help a little to help you figuring out how B-cells help T-cells. What a spectacular cover coloured by #micronaut Martin Oeggerli. 0103
Freddy Frischknecht @freddyfrischknecht.bsky.social · 11/11/2025Now recruiting several PhD students and postdocs for different projects of our excellence cluster SynthImmune: application.synthimmune.de For more info see perspective article below and synthimmune.deapplication.synthimmune.deSynthImmune - Online Application System 075
Reposted by Freddy FrischknechtPrakash Lab at Stanford @prakashlab.bsky.social · 24/10/2025“Cellular Olympics” our catalog of freeky ultra fast cellular superhero’s is freely available “Ann Rev of microbiology” www.annualreviews.org/content/jour... This is a compilation of world’s fastest single cell organisms - enjoy this buffet of rare delightful protists with mind bending speeds. 🧪 011341
Freddy Frischknecht @freddyfrischknecht.bsky.social · 06/10/2025What a way to start the week. Quick morning run at Les Embiez for the #EMBO /#ParaFRAP workshop Host-Parasite Interactions, where parasites truly rule. 0130
Freddy Frischknecht @freddyfrischknecht.bsky.social · 04/10/2025Beware of artifacts during low pressure fixation of mushroom samples. 060
Freddy Frischknecht @freddyfrischknecht.bsky.social · 02/10/2025Beautiful beasts: excited to see our first volume electron microscopy study on malaria parasites published: advanced.onlinelibrary.wiley.com/doi/10.1002/... revealing new insights into Plasmodium ookinete development. Thanks for great EMBL-Umea-Heidelberg collaboration. 1184
Freddy Frischknecht @freddyfrischknecht.bsky.social · 03/09/2025Early expansion microscopy: youtube.com/watch?v=56Fi...youtube.comMuppet Labs - Discover the Germ Enlarger! | The Muppet ShowYouTube video by Muppet Show Mania 060
Reposted by Freddy FrischknechtManuela Aguirre-Botero @maguirreb.bsky.social · 02/09/2025Curious about how antibodies can target Plasmodium sporozoites? Very happy to see this review out, it means a lot to me to finish my PhD research topic with a nice overview of what is known about how anti-CSP Abs neutralize the parasite in the mammalian host. 074
Freddy Frischknecht @freddyfrischknecht.bsky.social · 03/08/2025My favorite among my daughter’s new songs: peaceful warrior youtube.com/watch?v=hzmU...youtube.compeaceful warriorYouTube video by Ayla - Topic 040
Freddy Frischknecht @freddyfrischknecht.bsky.social · 27/07/2025Superb conference on Iron metabolism in early gametogenesis with fellow para-philosophers Bruce Boddey and Bruce Meissner. Great keynote by Bruce D. on 666 ways of regulation by Beast kinases. 1100
Freddy Frischknecht @freddyfrischknecht.bsky.social · 14/06/2025Finally published: discovery of an unusual Arp2/3 complex with surprising new function in transmission of #malaria #parasites. Great work by Franzi Hentzschel, Yvonne Sokolowski + David Jewanski + fantastic collaboration with Matthias Marti: www.nature.com/articles/s41... 34312
Reposted by Freddy FrischknechtFrançois Mayer @francoismayer.bsky.social · 13/06/2025Awesome malaria study out now in Nature Microbiology: An atypical Arp2/3 complex is required for Plasmodium DNA segregation and malaria transmission By Franziska Hentzschel, Matthias Marti, Freddy Frischknecht & colleagues! @freddyfrischknecht.bsky.social www.nature.com/articles/s41...nature.comAn atypical Arp2/3 complex is required for Plasmodium DNA segregation and malaria transmission - Nature MicrobiologyA unique Arp2/3 complex in malaria parasites enables DNA segregation during the rapid formation of male gametes by safeguarding the attachment of chromosomes to the mitotic spindle. 02810
Freddy Frischknecht @freddyfrischknecht.bsky.social · 11/06/2025Nice cover @molmicrounihoh.bsky.social features Blastocrithidia nonstop, a trypanosomatid parasite with a non‐canonical genetic code. Associated paper by Slava Yurchenko, Julius Lukes and colleagues describes its genetic transformation: onlinelibrary.wiley.com/doi/10.1111/... 091
Freddy Frischknecht @freddyfrischknecht.bsky.social · 23/05/2025Thanks so much to everyone for making BioMalPar XXI such a memorable and enjoyable conference. Looking forward to BioMalPar XXII on May 27-29, 2026. 0100
Reposted by Freddy FrischknechtEMBO @embo.org · 20/05/2025Learn about the #cytoskeleton: From #evolution to #biophysics and more at EMBO Workshop "Frontiers in Cytoskeleton Research" in Pune, India, 3–7 Nov Abstract submission deadline: 20 Jun Registration deadline: 15 Jul buff.ly/b7zAyw8 #EMBOcytoskeleton #StructuralBiology #CellBiology #EMBOevents 🧪buff.lyFrontiers in Cytoskeleton ResearchA key question in biology is how living cells adapt to highly complex functional requirements in the context of an organism, within which they need to develop complex morphologies, interact with many… 0216
Reposted by Freddy FrischknechtWolfgang Huber @wkhuber.bsky.social · 14/05/2025The SynthImmune project by Heidelberg University& partner institutes advances a "bottom-up" synthetic biology approach to immunotherapies. Hoping they do well in the German government's Excellence Strategy—anticipating the announcement on 22 May. Perspective article: www.nature.com/articles/s41...nature.comBottom-up synthetic immunology - Nature NanotechnologyThis Perspective highlights bottom-up molecular engineering and modular nanobiotechnological approaches for developing effective immunotherapeutics and their potential in personalized medicine. 0167
Freddy Frischknecht @freddyfrischknecht.bsky.social · 25/04/2025Come join us for an exciting @embo.org meeting in an enchanting location near Marseille 082
Freddy Frischknecht @freddyfrischknecht.bsky.social · 10/04/2025#malaria #parasites aren't exactly tolerated by our #liver cells. Preview with Justin Boddey on a great paper by Camila Marques da Silva and Samarchith P. Kurup in the same issue: Interferoning with #Plasmodium development in the liver: www.cell.com/cell-host-mi...cell.comInterferoning with Plasmodium development in the liverPlasmodium liver infection is limited by type I interferons (IFN-I) but the mechanisms remain unknown. In this issue of Cell Host & Microbe, Marques-da-Silva et al. reveal two IFN-I-induced pathways t... 010
Freddy Frischknecht @freddyfrischknecht.bsky.social · 06/04/2025Looking forward to teaching a @kakape.bsky.social inspired bridging seminar with Nora Heinzelmann on different aspects of modern biotechnology @marsilius.bsky.social. Looking forward to an interesting rollercoaster of opinions. 021
Freddy Frischknecht @freddyfrischknecht.bsky.social · 03/04/2025Live from Tübingen: the one and only Artur Scherf illuminating #Plasmodium var gene expression using his flower model of the infected red cell. 0101
Freddy Frischknecht @freddyfrischknecht.bsky.social · 31/03/2025Congrats Dr Annika Binder for a fantastic thesis and defense on microtubule binding proteins of #malaria #parasites exactly 25 years after I got my Dr for something with #actin and poxviruses and almost failed a question on, well, microtubule binding proteins. 0121
Freddy Frischknecht @freddyfrischknecht.bsky.social · 25/03/2025Finally: Plasmodium actin filaments visualized in all their glory. Congrats Josie and Vojtech: www.embopress.org/doi/full/10....embopress.orgMolecular architecture of glideosome and nuclear F-actin in Plasmodium falciparum | EMBO reportsimageimageThis study directly visualises actin cytoskeleton in Plasmodium falciparum sporozoites under native conditions and investigates its structural transitions during locomotion. P. falciparum a... 0133
Freddy Frischknecht @freddyfrischknecht.bsky.social · 14/03/2025And here with two previous winners both proudly wearing the traditional leopard skin that comes along with the prize. Go boldly. 091
Freddy Frischknecht @freddyfrischknecht.bsky.social · 07/03/2025A short but wonderful course on #parasites for Master and PhD students organized by the one and only Jude Przyborski. Apply. 043
Reposted by Freddy FrischknechtLabEx ParaFrap @parafrap.bsky.social · 25/02/2025📅 Save the Date! The EMBO Workshop "Host-Parasite Relationship: From Mechanisms to Control Strategies" organized by @ParaFrap will take place on October 5-8, 2025, at Les Embiez Island. Stay updated on registration opening —enter your email here: coming-soon.embo.org/w25-83 #Science #Parasite 0168
Reposted by Freddy Frischknechtsturalph.bsky.social @sturalph.bsky.social · 24/02/2025Last day to submit an abstract for BioMalPar 2025, don’t miss out 011
Reposted by Freddy FrischknechtMaria Bernabeu @mariabernabeu.bsky.social · 19/02/2025Happy to announce that we are running the third edition of the EMBL-UNESCO residency on infection biology. If you are an African female scientist and would like to do a research stay at EMBL, my lab is a possible hosting group. Deadline March 31st! www.embl.org/about/info/s...embl.orgEMBL-UNESCO Residency in Infection Biology Research – Scientific Visitor Programmearrow-button-downarrow-button-downarrow-button-downarrow-button-downarrow-button-downarrow-button-downarrow-button-dow... 085
Reposted by Freddy FrischknechtMichael Way @drmichaelway.bsky.social · 12/02/2025Infection: pathogens, hosts, and microbiomes EMBO:EMBL meeting - great line up of speakers. Abstract deadline is less than a month away! You don't want to miss this one if you are interested in infection biology. 043
Freddy Frischknecht @freddyfrischknecht.bsky.social · 06/02/2025Gametes and sporozoites: Happy to see our paper probing the importance of #microtubule inner proteins in #Plasmodium published in final form @pnas.org - Sporozoites can do without MIPs but gametes cannot. www.pnas.org/doi/10.1073/... 040
Reposted by Freddy FrischknechtTrends in Parasitology @cp-trendsparasitol.bsky.social · 23/01/2025Review in this collection: The #Plasmodium #circumsporozoite protein #CSP, authored by Mirko Singer, Sachie Kanatani, Stefano Garcia Castillo, @freddyfrischknecht.bsky.social, and Photini Sinnis. #Malaria #Vaccine #Mosquito #Oocyst #Adhesion #GPIanchor www.cell.com/trends/paras... 031
Freddy Frischknecht @freddyfrischknecht.bsky.social · 15/01/2025I usually prefer wearing @mblscience.bsky.social BoP course T-shirts, but seeing a Hugo Boss sporozoite shirt, I could no resist. That Stefan had nearly the same left no doubt that the two projects would be funded 🙂 070
Freddy Frischknecht @freddyfrischknecht.bsky.social · 09/01/2025Join the Biology of Parasitism (BoP) course at MBL Woods Hole for an unforgetttable summer of science and fun, meet wonderful teachers and make friends for life: www.mbl.edu/education/ad... 0115
Freddy Frischknecht @freddyfrischknecht.bsky.social · 09/01/2025Superb and authorative historical review by Julien Guizetti on imaging malaria parasites. From Laveran to live-cell STED in Journal of Microscopy: onlinelibrary.wiley.com/doi/full/10.... 020
Freddy Frischknecht @freddyfrischknecht.bsky.social · 20/12/2024I always wanted to name a protein after a Greek goddess or nymph and here we go: journals.plos.org/plospathogen... Happy holidays everyonejournals.plos.orgAPEX-based proximity labeling in Plasmodium identifies a membrane protein with dual functions during mosquito infectionAuthor summary Malaria parasites are transmitted by and to mosquitoes. Blocking either of these transmission steps would stop the parasite life cycle. Hence, identification of new proteins that are es... 071
Freddy Frischknecht @freddyfrischknecht.bsky.social · 20/12/2024Exciting opportunity for students from Africa: a master program on infection biology in Lambarene, Gabon and Germany: uni-tuebingen.de/en/study/fin... 010
Freddy Frischknecht @freddyfrischknecht.bsky.social · 18/12/2024Beautiful blendering of #Plasmodium sporozoites migrating in 3D. Thanks and congrats to Leon @lettermann.bsky.social for being included in this lovely calender from @dfgpublic.bsky.social. Happy to just receive renewal funding for this project within our network on Physics of Parasitism. 020
Freddy Frischknecht @freddyfrischknecht.bsky.social · 18/12/2024Our new outreach movie without words in an attempt on being creative illustrating how pathogen exit can be blocked to stop diseases. Thanks to Matthias and Yvonne and to @spp2225.bsky.social @dfgpublic.bsky.social for funding 020