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Freddy Frischknecht

@freddyfrischknecht.bsky.social
467 followers 107 following 94 posts

Cell biologist working on malaria parasites and interested in host pathogen interactions, imaging, teaching, space exploration, gardening.

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Reposted by Freddy Frischknecht
Fever: Global Histories of (a) Disease @feverprojecthd.bsky.social · 16/06/2026
Deadline extended! Applications open until 1 July 2026!
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Reposted by Freddy Frischknecht
Fever: Global Histories of (a) Disease @feverprojecthd.bsky.social · 21/05/2026
Feel the heat? Join us in Heidelberg for an interdisciplinary summer school on FEVER. Stefanie Gänger, Ulrich Schwarz and Freddy Frischknecht welcome 30 participants and speakers incl. science journalist Kai Kupferschmidt to our Institute of Advanced Studies. Info & registration: lnkd.in/d7Yt5tf9
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Freddy Frischknecht @freddyfrischknecht.bsky.social · 30/03/2026
And teaching does make a difference: Just received the news from Pedro, that @mblbop.bsky.social 2024 fellow Linda obtained a postdoctoral fellowship to continue her career @gwu1821.bsky.social. That follows from a student who admitted this noon to join my lab because he listen to one of my talks.
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Reposted by Freddy Frischknecht
Institut Pasteur Education @pasteuredu.bsky.social · 27/02/2026
✨ One year on, we honor Spencer Shorte. On Jan 28, 2026, Institut Pasteur paid tribute to a visionary scientist and human leader. His legacy lives on through the PPU–Research & Technology track, uniting research & innovation as he envisioned. Inspiring future generations.
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Freddy Frischknecht @freddyfrischknecht.bsky.social · 30/01/2026
Screw it. It's weekend. My daughters new song: open.spotify.com/intl-de/trac... placed just below mighty Bruce Springsteens Streets of Minneapolis on the German Friday music stream list.
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Ulrich Schwarz @ulrichschwarz.bsky.social · 23/01/2026
(1/2) Our work with @freddyfrischknecht.bsky.social on the chirality of malaria parasites has found its home in the January issue of @natphys.nature.com: www.nature.com/articles/s41... Moreover, we are very happy that it comes with a news and views article 👍❤️😀
nature.com
Chirality of malaria parasites determines their motion patterns - Nature Physics
Malaria parasites move on helical trajectories when infecting their hosts. Now it is shown that they use right-handed chirality to control their motion patterns, and that this chirality is linked to t...
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Freddy Frischknecht @freddyfrischknecht.bsky.social · 01/01/2026
Happy New Year from Heidelberg and looking forward to SingMalNet in Singapore in February, BioMalPar in sunny Heidelberg in May and other adventures.
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Freddy Frischknecht @freddyfrischknecht.bsky.social · 17/12/2025
This might well become your best summer experience
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Freddy Frischknecht @freddyfrischknecht.bsky.social · 04/12/2025
Join us (again) for another fantastic BioMalPar meeting @embl.org and also a great pre-meeting @ciid-heidelberg.bsky.social
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Ulrich Schwarz @ulrichschwarz.bsky.social · 24/11/2025
📢 Paper alert 📢 Chirality is known to be important for the movement of microorganisms and active matter. In our new paper out today in @natphys.nature.com, we show that chirality is used by malaria parasites to control their motion patterns: doi.org/10.1038/s415... Here comes a 🧵 ... (1/9)
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Journal of Cell Science @jcellsci.bsky.social · 21/11/2025
Mole's Comedia III. Purgatorio. Canto I–XXIV. journals.biologists.com/jcs/article/...
Drawing of an anthropomorphised Mole in a robe next to a figure with robes and a crown. ‘Beings’ in a ditch are holding out sheets of paper to Mole. The location looks creepy. The text below the image says, ‘We land, and I see hundreds of like souls. Holding manuscripts in clenched hands… “It is nearly ready” he say…’
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Freddy Frischknecht @freddyfrischknecht.bsky.social · 11/11/2025
Beautiful beasts (2): Thanks Ian for allowing us to help a little to help you figuring out how B-cells help T-cells. What a spectacular cover coloured by #micronaut Martin Oeggerli.
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Freddy Frischknecht @freddyfrischknecht.bsky.social · 11/11/2025
Now recruiting several PhD students and postdocs for different projects of our excellence cluster SynthImmune: application.synthimmune.de For more info see perspective article below and synthimmune.de
application.synthimmune.de
SynthImmune - Online Application System
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Reposted by Freddy Frischknecht
Prakash Lab at Stanford @prakashlab.bsky.social · 24/10/2025
“Cellular Olympics” our catalog of freeky ultra fast cellular superhero’s is freely available “Ann Rev of microbiology” www.annualreviews.org/content/jour... This is a compilation of world’s fastest single cell organisms - enjoy this buffet of rare delightful protists with mind bending speeds. 🧪
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Freddy Frischknecht @freddyfrischknecht.bsky.social · 06/10/2025
What a way to start the week. Quick morning run at Les Embiez for the #EMBO /#ParaFRAP workshop Host-Parasite Interactions, where parasites truly rule.
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Freddy Frischknecht @freddyfrischknecht.bsky.social · 04/10/2025
Beware of artifacts during low pressure fixation of mushroom samples.
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Freddy Frischknecht @freddyfrischknecht.bsky.social · 02/10/2025
Beautiful beasts: excited to see our first volume electron microscopy study on malaria parasites published: advanced.onlinelibrary.wiley.com/doi/10.1002/... revealing new insights into Plasmodium ookinete development. Thanks for great EMBL-Umea-Heidelberg collaboration.
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Freddy Frischknecht @freddyfrischknecht.bsky.social · 03/09/2025
Early expansion microscopy: youtube.com/watch?v=56Fi...
youtube.com
Muppet Labs - Discover the Germ Enlarger! | The Muppet Show
YouTube video by Muppet Show Mania
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Reposted by Freddy Frischknecht
Manuela Aguirre-Botero @maguirreb.bsky.social · 02/09/2025
Curious about how antibodies can target Plasmodium sporozoites? Very happy to see this review out, it means a lot to me to finish my PhD research topic with a nice overview of what is known about how anti-CSP Abs neutralize the parasite in the mammalian host.
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Freddy Frischknecht @freddyfrischknecht.bsky.social · 03/08/2025
My favorite among my daughter’s new songs: peaceful warrior youtube.com/watch?v=hzmU...
youtube.com
peaceful warrior
YouTube video by Ayla - Topic
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Freddy Frischknecht @freddyfrischknecht.bsky.social · 27/07/2025
Superb conference on Iron metabolism in early gametogenesis with fellow para-philosophers Bruce Boddey and Bruce Meissner. Great keynote by Bruce D. on 666 ways of regulation by Beast kinases.
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Freddy Frischknecht @freddyfrischknecht.bsky.social · 14/06/2025
Finally published: discovery of an unusual Arp2/3 complex with surprising new function in transmission of #malaria #parasites. Great work by Franzi Hentzschel, Yvonne Sokolowski + David Jewanski + fantastic collaboration with Matthias Marti: www.nature.com/articles/s41...
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François Mayer @francoismayer.bsky.social · 13/06/2025
Awesome malaria study out now in Nature Microbiology: An atypical Arp2/3 complex is required for Plasmodium DNA segregation and malaria transmission By Franziska Hentzschel, Matthias Marti, Freddy Frischknecht & colleagues! @freddyfrischknecht.bsky.social www.nature.com/articles/s41...
nature.com
An atypical Arp2/3 complex is required for Plasmodium DNA segregation and malaria transmission - Nature Microbiology
A unique Arp2/3 complex in malaria parasites enables DNA segregation during the rapid formation of male gametes by safeguarding the attachment of chromosomes to the mitotic spindle.
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Freddy Frischknecht @freddyfrischknecht.bsky.social · 11/06/2025
Nice cover @molmicrounihoh.bsky.social features Blastocrithidia nonstop, a trypanosomatid parasite with a non‐canonical genetic code. Associated paper by Slava Yurchenko, Julius Lukes and colleagues describes its genetic transformation: onlinelibrary.wiley.com/doi/10.1111/...
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Freddy Frischknecht @freddyfrischknecht.bsky.social · 23/05/2025
Thanks so much to everyone for making BioMalPar XXI such a memorable and enjoyable conference. Looking forward to BioMalPar XXII on May 27-29, 2026.
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Reposted by Freddy Frischknecht
EMBO @embo.org · 20/05/2025
Learn about the #cytoskeleton: From #evolution to #biophysics and more at EMBO Workshop "Frontiers in Cytoskeleton Research" in Pune, India, 3–7 Nov Abstract submission deadline: 20 Jun Registration deadline: 15 Jul buff.ly/b7zAyw8 #EMBOcytoskeleton #StructuralBiology #CellBiology #EMBOevents 🧪
buff.ly
Frontiers in Cytoskeleton Research
A key question in biology is how living cells adapt to highly complex functional requirements in the context of an organism, within which they need to develop complex morphologies, interact with many…
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Wolfgang Huber @wkhuber.bsky.social · 14/05/2025
The SynthImmune project by Heidelberg University& partner institutes advances a "bottom-up" synthetic biology approach to immunotherapies. Hoping they do well in the German government's Excellence Strategy—anticipating the announcement on 22 May. Perspective article: www.nature.com/articles/s41...
nature.com
Bottom-up synthetic immunology - Nature Nanotechnology
This Perspective highlights bottom-up molecular engineering and modular nanobiotechnological approaches for developing effective immunotherapeutics and their potential in personalized medicine.
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Freddy Frischknecht @freddyfrischknecht.bsky.social · 25/04/2025
Come join us for an exciting @embo.org meeting in an enchanting location near Marseille
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Freddy Frischknecht @freddyfrischknecht.bsky.social · 10/04/2025
#malaria #parasites aren't exactly tolerated by our #liver cells. Preview with Justin Boddey on a great paper by Camila Marques da Silva and Samarchith P. Kurup in the same issue: Interferoning with #Plasmodium development in the liver: www.cell.com/cell-host-mi...
cell.com
Interferoning with Plasmodium development in the liver
Plasmodium liver infection is limited by type I interferons (IFN-I) but the mechanisms remain unknown. In this issue of Cell Host & Microbe, Marques-da-Silva et al. reveal two IFN-I-induced pathways t...
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Freddy Frischknecht @freddyfrischknecht.bsky.social · 06/04/2025
Looking forward to teaching a @kakape.bsky.social inspired bridging seminar with Nora Heinzelmann on different aspects of modern biotechnology @marsilius.bsky.social. Looking forward to an interesting rollercoaster of opinions.
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Freddy Frischknecht @freddyfrischknecht.bsky.social · 03/04/2025
Live from Tübingen: the one and only Artur Scherf illuminating #Plasmodium var gene expression using his flower model of the infected red cell.
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Freddy Frischknecht @freddyfrischknecht.bsky.social · 31/03/2025
Congrats Dr Annika Binder for a fantastic thesis and defense on microtubule binding proteins of #malaria #parasites exactly 25 years after I got my Dr for something with #actin and poxviruses and almost failed a question on, well, microtubule binding proteins.
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Freddy Frischknecht @freddyfrischknecht.bsky.social · 25/03/2025
Finally: Plasmodium actin filaments visualized in all their glory. Congrats Josie and Vojtech: www.embopress.org/doi/full/10....
embopress.org
Molecular architecture of glideosome and nuclear F-actin in Plasmodium falciparum | EMBO reports
imageimageThis study directly visualises actin cytoskeleton in Plasmodium falciparum sporozoites under native conditions and investigates its structural transitions during locomotion. P. falciparum a...
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Freddy Frischknecht @freddyfrischknecht.bsky.social · 14/03/2025
And here with two previous winners both proudly wearing the traditional leopard skin that comes along with the prize. Go boldly.
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Freddy Frischknecht @freddyfrischknecht.bsky.social · 07/03/2025
A short but wonderful course on #parasites for Master and PhD students organized by the one and only Jude Przyborski. Apply.
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LabEx ParaFrap @parafrap.bsky.social · 25/02/2025
📅 Save the Date! The EMBO Workshop "Host-Parasite Relationship: From Mechanisms to Control Strategies" organized by @ParaFrap will take place on October 5-8, 2025, at Les Embiez Island. Stay updated on registration opening —enter your email here: coming-soon.embo.org/w25-83 #Science #Parasite
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Freddy Frischknecht @freddyfrischknecht.bsky.social · 24/02/2025
Germany, verscholzt.
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Reposted by Freddy Frischknecht
sturalph.bsky.social @sturalph.bsky.social · 24/02/2025
Last day to submit an abstract for BioMalPar 2025, don’t miss out
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Maria Bernabeu @mariabernabeu.bsky.social · 19/02/2025
Happy to announce that we are running the third edition of the EMBL-UNESCO residency on infection biology. If you are an African female scientist and would like to do a research stay at EMBL, my lab is a possible hosting group. Deadline March 31st! www.embl.org/about/info/s...
embl.org
EMBL-UNESCO Residency in Infection Biology Research – Scientific Visitor Programmearrow-button-downarrow-button-downarrow-button-downarrow-button-downarrow-button-downarrow-button-downarrow-button-dow...
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Michael Way @drmichaelway.bsky.social · 12/02/2025
Infection: pathogens, hosts, and microbiomes EMBO:EMBL meeting - great line up of speakers. Abstract deadline is less than a month away! You don't want to miss this one if you are interested in infection biology.
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Freddy Frischknecht @freddyfrischknecht.bsky.social · 06/02/2025
Gametes and sporozoites: Happy to see our paper probing the importance of #microtubule inner proteins in #Plasmodium published in final form @pnas.org - Sporozoites can do without MIPs but gametes cannot. www.pnas.org/doi/10.1073/...
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Trends in Parasitology @cp-trendsparasitol.bsky.social · 23/01/2025
Review in this collection: The #Plasmodium #circumsporozoite protein #CSP, authored by Mirko Singer, Sachie Kanatani, Stefano Garcia Castillo, @freddyfrischknecht.bsky.social, and Photini Sinnis. #Malaria #Vaccine #Mosquito #Oocyst #Adhesion #GPIanchor www.cell.com/trends/paras...
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Freddy Frischknecht @freddyfrischknecht.bsky.social · 15/01/2025
I usually prefer wearing @mblscience.bsky.social BoP course T-shirts, but seeing a Hugo Boss sporozoite shirt, I could no resist. That Stefan had nearly the same left no doubt that the two projects would be funded 🙂
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Freddy Frischknecht @freddyfrischknecht.bsky.social · 09/01/2025
Join the Biology of Parasitism (BoP) course at MBL Woods Hole for an unforgetttable summer of science and fun, meet wonderful teachers and make friends for life: www.mbl.edu/education/ad...
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Freddy Frischknecht @freddyfrischknecht.bsky.social · 09/01/2025
Superb and authorative historical review by Julien Guizetti on imaging malaria parasites. From Laveran to live-cell STED in Journal of Microscopy: onlinelibrary.wiley.com/doi/full/10....
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Freddy Frischknecht @freddyfrischknecht.bsky.social · 01/01/2025
Happy 2025 from Heidelberg
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Freddy Frischknecht @freddyfrischknecht.bsky.social · 20/12/2024
I always wanted to name a protein after a Greek goddess or nymph and here we go: journals.plos.org/plospathogen... Happy holidays everyone
journals.plos.org
APEX-based proximity labeling in Plasmodium identifies a membrane protein with dual functions during mosquito infection
Author summary Malaria parasites are transmitted by and to mosquitoes. Blocking either of these transmission steps would stop the parasite life cycle. Hence, identification of new proteins that are es...
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Freddy Frischknecht @freddyfrischknecht.bsky.social · 20/12/2024
Exciting opportunity for students from Africa: a master program on infection biology in Lambarene, Gabon and Germany: uni-tuebingen.de/en/study/fin...
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Freddy Frischknecht @freddyfrischknecht.bsky.social · 18/12/2024
Beautiful blendering of #Plasmodium sporozoites migrating in 3D. Thanks and congrats to Leon @lettermann.bsky.social for being included in this lovely calender from @dfgpublic.bsky.social. Happy to just receive renewal funding for this project within our network on Physics of Parasitism.
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Freddy Frischknecht @freddyfrischknecht.bsky.social · 18/12/2024
Our new outreach movie without words in an attempt on being creative illustrating how pathogen exit can be blocked to stop diseases. Thanks to Matthias and Yvonne and to @spp2225.bsky.social @dfgpublic.bsky.social for funding
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