The successive emergence of SARS-CoV-2 variants with altered tissue tropism has progressively decoupled transmissibility from lower respiratory tract pathogenicity. Omicron lineages transmit exception...

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Researchers have uncovered new details about a key norovirus protein. They provide a new framework for future research into the virus and antiviral drugs.

Swine are a crucial species in influenza A virus (IAV) ecology, capable of supporting replication and consequently evolution of human, avian, and s...

Human seasonal influenza evolves rapidly, necessitating twice yearly decisions about whether to update the strains in the vaccine. To help inform this decision, we have been using high-throughput sequ...

Hedgehog merbecoviruses utilize hedgehog aminopeptidase N, but not the human orthologue, as their entry receptor. Structural resolution of the glycoprotein–receptor interface reveals the molecular int...

Postdoctoral Scientist Salary £42,694 per annum Fixed term, 3 years MRC Laboratory of Molecular Biology, Cambridge, UK To work in the group of Dr M...

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The ciliary transition zone (TZ) regulates ciliary proteome composition, yet its molecular architecture, protein content, and contribution to motile ciliopathies remain poorly defined. We applied in situ cryo-electron tomography and subtomogram averaging ...

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There is still limited data reported on virus diversity in South American bats. In this study, the authors report a divergent betacoronavirus with a functional furin cleavage site in South American ba...

The West Nile virus has been confirmed in nine people in the Netherlands since the start of the summer, according to the National Institute for Public Health and the Environment (RIVM). The virus is…

This study identifies a broad-spectrum IAV inhibitor that blocks multiple functions of NS1 protein. The critical sites on NS1 targeted by the inhibitor are validated in vitro and in vivo, supporting t...

Researchers identified MWAC-3634, a small molecule that blocks Ebola virus entry by stabilizing its surface glycoprotein, revealing a distinct anti-Ebola strategy. Oral or injected treatment improved ...

During replisome assembly of monkeypox virus, the hexameric helicase–primase E5 undergoes large-scale conformational changes that allow two of its primase domains to interact with the polymerase F8 th...

Nirmatrelvir–ritonavir for 15 days or 25 days showed no evidence of benefit in long COVID in any of the three phenotypes studied. These findings suggest additional approaches to measuring the symptom ...

De vrouw heeft het virus in Nederland opgelopen en kreeg daarna hersenvliesontsteking, meldt stadsomroep AT5.

About 175 students and supervisors from Breda University of Applied Sciences fell ill during an orientation camp in Belgium.

PilC/PilY1 proteins are tip-located adhesins of type IV pili (T4P) that are critical for T4P function in diverse behaviors including twitching moti...