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Lillemeier lab

@lillemeier-lab.bsky.social
268 followers 210 following 166 posts

We are a research group at University of Freiburg that studies the molecular mechanisms of T cell activation and how to use them for immunotherapy. lillemeier.biologie.uni-freiburg.de

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sfb1160.bsky.social @sfb1160.bsky.social · 22h
🧬 From TCR signalling to gene therapy and CAR-T cells! Our final session at #SFB1160 brought together Claire Booth, Susana Minguet, Valeria Melendez, Anna-Sophia Baur & Chenqi Xu — with patient stories, new therapeutic ideas and even a friendship born from scientific rivalry. #IMPATH
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Wolfgang Hess @cyanolab.bsky.social · 16h
Bakteriopolis, now in Freiburg. A cool, interactive exhibition about the tiny ones. Mo-Fri 10:00 to 16:00, other times can be arranged.
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Prof Danny Altmann @daltmann.bsky.social · 09/10/2026
Capturing the full spectrum of T cell responses with spectral flow cytometry academic.oup.com/ooim/article...
academic.oup.com
Capturing the full spectrum of T cell responses with spectral flow cytometry
Abstract. Over a decade has passed since the first commercial spectral flow cytometry (SFC) instrument was introduced. Unlike conventional flow cytometers,
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sfb1160.bsky.social @sfb1160.bsky.social · 08/10/2026
🎉 The #SFB1160 Symposium starts today! We’re excited to welcome an outstanding line-up of international speakers to Freiburg! Take a look at who’s joining us for three days of immunology research and scientific exchange! 👇 #IMPATH #Immunology
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Jean Léon Maître @maitrejl.bsky.social · 06/10/2026
📣Our department is hiring a new group leader!📣 Want to start your team in a vibrant scientific environment in the center of Paris? I was very lucky to do that 10 years ago, reach out if you have any question. Apply by December 18th: jpi-recruitment-curie-umr3215-u934.curie.fr
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SFB 1348 @sfb1348.bsky.social · 07/10/2026
... co-organized by and featuring Seraphine Wegner @sfb1348.bsky.social @uni-muenster.de
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Rita Strack @ritastrack.bsky.social · 07/10/2026
Opportunity alert!
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Kilian Schober @kischober.bsky.social · 06/10/2026
Interested in antigen-specific T cell analyses for clinical immunomonitoring? Have a look at our review, just out in @natureportfolio.nature.com Protocols: www.nature.com/articles/s41... Led by S. Lazzaro and S. Koch, Curevac. Special feature: The Supplementary Tutorial (interactive decision aid)
nature.com
T cell immunomonitoring: a comparative analysis of traditional and novel methods to quantify and characterize human antigen-specific T cells - Nature Protocols
We present a comparative analysis review of traditional and cutting-edge technologies for clinical profiling of antigen-specific T cells, highlighting their principles, applications, benefits and limi...
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EFIS_Immunology @efis-immunology.bsky.social · 06/10/2026
📣 T Cell Connect Europe – Online Immunology Lecture Series kicking off after summer break TODAY! 📅 Oct 6th at 17:00 🎙️ Presenters: Taras Kreslavskiy from Karolinska Institute and Dietmar Herndler-Brandstetter from Medical University of Vienna. 🔗 For more information and zoom link: www.t-cells.eu
t-cells.eu
T-Cell Connect Europe
EFIS-IL study group T CELL CONNECT EUROPE (TCC_EUROPE)
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Jean-Yves Tinevez @jytinevez.bsky.social · 05/10/2026
We have a position open in our core facility in the @pasteur.fr . Please share it and / or apply! forum.image.sc/t/research-e...
forum.image.sc
Research engineer in Bioimage Analysis. Institut Pasteur, Image Analysis Hub - 2026
Dear all Below is an announcement for a permanent position as a Research Engineer in the Institut Pasteur, Paris. There is a flyer attached at the bottom. We are looking ideally for a Bioimage An...
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Rockefeller University Press @rupress.org · 05/10/2026
In @jem.org, Gößwein, Ulmert, @srosshart.bsky.social, and @jonatcoquet.bsky.social describe how colonizing laboratory mice with a naturally evolved #microbiota can restore important features of mammalian physiology & how this can benefit translational research. rupress.org/jem/article/...
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Stephan P. Rosshart @srosshart.bsky.social · 05/10/2026
Reposts appreciated! Natural microbiota-based mouse models - particularly Wildlings - improve reproducibility & translation across a remarkable range of biomedical fields. Our new @jem.org Found in Translation! Thanks Isabel, Mario & @jonatcoquet.bsky.social! doi.org/10.1084/jem....
doi.org
Natural microbiota–based mouse models: A platform to fast-track translation of fundamental discoveries into the clinic
Conventional laboratory mice are invaluable tools in biomedical research, but their restricted microbial complexity limits their translational relevance. H
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Deutsche Forschungsgemeinschaft @dfg.de · 05/10/2026
Peter Hegemann und Georg Nagel haben gemeinsam mit Karl Deisseroth entscheidende Grundlagen für die Optogenetik geschaffen – und wurden nun dafür mit dem Nobelpreis ausgezeichnet. 👏 Wir freuen uns, dass die DFG diese Forschung auf Teilen ihres Weges unterstützen konnte. Dazu mehr: sohub.io/hz4j
Illustration von Peter Hegemann und Georg Nagel, darunter der Schriftzug:
Herzlichen Glückwunsch zum Nobelpreis!
In der Medizin für Entdeckungen in der Optogenetik
Unten DFG-Logo
Illus: Niklas Elmehed / Nobel Prize
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Global Immunotalks @globalimmuno.bsky.social · 05/10/2026
Looking forward to our next #globalimmuno talk this Wednesday, October 7, 2026, at 9am PST, noon EST, 4pm GMT by Dr. Wanli Liu. Title: “Aberrant B lymphocyte Activation and the Associated Diseases” ZOOM LINK: us06web.zoom.us/webinar/regi... LIVE ON YOUTUBE: www.youtube.com/@GLOBALIMMUNOTALKS
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Waggoner Lab @labwaggoner.bsky.social · 05/10/2026
@biorxivpreprint.bsky.social exhausted CD8 ⁺ T cells retain inducible effector capacity through IL‑12 and IL‑18 stimulation www.biorxiv.org/content/10.6...
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Max Delbrück Center @mdc-berlin.bsky.social · 05/10/2026
Congratulations to Karl Deisseroth, Peter Hegemann, and Georg Nagel on the 2026 Nobel Prize in Physiology or Medicine! 🎉 We’re especially delighted for Berlin-based Hegemann, whose work helped lay the foundations for optogenetics – now an important tool in research at the #mdcBerlin and beyond. 👇
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Ursula von der Leyen @vonderleyen.ec.europa.eu · 05/10/2026
Herzlichen Glückwunsch an Peter Hegemann and Georg Nagel and their American colleague Karl Deisseroth for winning this year's Nobel Prize for medicine. Their research marks a breakthrough in our understanding of the human brain.
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#SingleCell preprints @prepub-singlecell.bsky.social · 29/09/2026
Functional Deorphanization of Tumor-reactive TCRs Uncovers a Landscape of Shared, Immune Dominant Antigens across Cancers #SingleCell 🧪🧬🖥️ www.biorxiv.org/content/10.64898/20…
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CIBSS – Centre for Integrative Biological Signalling Studies @cibss.bsky.social · 02/10/2026
The @uni-freiburg.de is once again a University of Excellence!✨ This is a tremendous success for the entire University! At CIBSS, we are proud to have helped lay the foundations for this achievement together with #FutureForests. But something important has already emerged along the way:
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The Powrie Lab @powrielab.bsky.social · 02/10/2026
Interested in joining the Powrie Lab for a PhD? Applications are open now for two projects with us!👩‍🔬🧑‍🔬 Find out more over at: www.kennedy.ox.ac.uk/study-with-us or via the studentship the links on our lab webpage: www.ndorms.ox.ac.uk/research/res... @kiroxford.bsky.social @ndorms.bsky.social
kennedy.ox.ac.uk
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 02/10/2026
SEEKER: A genome-scale library-on-library screening platform for deciphering T cell recognition of antigen www.biorxiv.org/content/10.64898/20…
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Waggoner Lab @labwaggoner.bsky.social · 02/10/2026
Functional evaluation of TCR-pMHC pairs at scale allows in silico TCR reactivity prediction @cp-immunity.bsky.social www.cell.com/immunity/ful... @schumacher-lab.bsky.social @nkinl.bsky.social
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Ingelfinger Lab @ingelfingerlab.bsky.social · 02/10/2026
Upcoming CRC1479 Seminar Felix Hartmann (DKFZ): “Spatial Quantification of Cellular Metabolic States in Human Cancer” 📅 9 Oct. 2026 🕐 1:00 pm CEST 📍 ZTZ, Breisacher Str. 115, 79106 Freiburg, Room 00.057/2 💻 Online: uniklinik-freiburg.webex.com/uniklinik-fr... Everyone is warmly invited to join!
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Milena Schuhmacher @mschuhmacher.bsky.social · 01/10/2026
So excited to join the Perutz! #lipidtime I will also be looking for new PhD students and postdocs soon ☺️
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Michael White @mtwhite.bsky.social · 01/10/2026
lnkd.in/exDnxM_6 My team at Institut Pasteur Paris, in collaboration with the team of Dr Makhtar Niang at Institut Pasteur de Dakar, are searching for prospective PhD students through the Pasteur-Paris University International Doctoral Program.
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Global Immunotalks @globalimmuno.bsky.social · 01/10/2026
Dr. Steffen Massberg’s seminar entitled “Cellular Conversations between Thrombosis and Immunity” is now available on YouTube youtube.com/live/8e0WPls... Please ask questions in the comment section for Steffen. Hope you enjoy it!
youtube.com
YouTube
Share your videos with friends, family, and the world
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International Union of Immunological Societies @iuis-online.bsky.social · 01/10/2026
Missed a live IUIS webinar? Every 2026 session is free on demand on #ImmunoHub. Create your account: loom.ly/ZPwIVCQ #ImmunologyWithoutBorders #Immunology
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Waggoner Lab @labwaggoner.bsky.social · 01/10/2026
Spatially confined IL-12 programs CAR-NK through mTORC1 to coordinate antitumor immune networks @danafarber.bsky.social @theaacr.bsky.social doi.org/10.1158/2159...
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Joe Sabatino @jsabatino37.bsky.social · 01/10/2026
Reminder! If you are interested applying to our MS and Neuroimmunology fellowship, please attend our virtual Open House on Friday, October 2 at 10-11 am PT. We offer clinical and clinician-scientist training tracks Registration here: ucsf.zoom.us/webinar/regi...
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Florian Ingelfinger @florianingelfinger.bsky.social · 01/10/2026
1/3 Deep generative modeling coming to cytometry! 🔬 CytoVI is now in Nature Methods: integrate flow cytometry, mass cytometry & CITE-seq, predict missing markers, and discover disease-associated cell states. www.nature.com/articles/s41...
nature.com
CytoVI: deep generative modeling of antibody-based single cell data - Nature Methods
CytoVI is a deep generative model for statistically rigorous analysis of antibody-based single-cell data.
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sfb1160.bsky.social @sfb1160.bsky.social · 30/09/2026
📢 Final registration day! Join us at #SFB1160 #Symposium “IMPAIRED IMMUNITY: From Immunopathology to Immune Reconstitution”. Date: October 8–10, 2026 Venue: KG I, #UniversityOfFreiburg Program: www.sfb1160.uni-freiburg.de/symposium-20... Be part of great #Immunology #Research #ScientificExchange
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Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) @fmpberlin.bsky.social · 29/09/2026
🔬 Two PhD positions in Biophysics/Structural Biology at FMP Berlin! The Research Unit Molecular Biophysics at the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), led by Adam Lange, is looking for two PhD students. Applications are open until November, 30.
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Schumacher Lab @schumacher-lab.bsky.social · 29/09/2026
Hi, we would like to introduce PAIR-Scan, an HLA-agnostic library-on-library screening technology that can identify reactive TCR–antigen pairs with optimal killing activity among up to ~100,000 possible candidate pairs in a single-step. 🧵(1/7) www.biorxiv.org/content/10.6...
biorxiv.org
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Jez Carlton @jezcarlton.bsky.social · 28/09/2026
Hey! Submit your papers, and spread the word, this will be great! Thanks for inviting us @jcellsci.bsky.social and great to work with @pihanson.bsky.social on this issue!
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Waggoner Lab @labwaggoner.bsky.social · 28/09/2026
@biorxivpreprint.bsky.social B cells sustain tumor-specific CD4 T cells to promote response to PD-1 targeted therapy www.biorxiv.org/content/10.6... @kamphorstlab.bsky.social
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Global Immunotalks @globalimmuno.bsky.social · 28/09/2026
Looking forward to our next #globalimmuno talk this Wednesday, September 30, 2026, at 9am PST, noon EST, 4pm GMT by Dr. Steffen Massberg . Title: “Cellular Conversations between Thrombosis and Immunity” ZOOM LINK: us06web.zoom.us/webinar/regi... LIVE ON YOUTUBE: www.youtube.com/@GLOBALIMMUNOTALK
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Lillemeier lab @lillemeier-lab.bsky.social · 28/09/2026
Congratulations!
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SFB 1348 @sfb1348.bsky.social · 28/09/2026
Looking forward to an exciting @sfb1348.bsky.social @uni-muenster.de seminar with Fiona Kearns @kearnslab.bsky.social (Uni of Freiburg) on October 1. She will speak about “Emerging Opportunities in Biophysics: Glycoprotein Characterization by Molecular Dynamics Simulations”. Everyone's welcome!
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Global Immunotalks @globalimmuno.bsky.social · 25/09/2026
Dr. Chloe Villani’s seminar entitled “Cracking the Code of Checkpoint Toxicity Mechanisms” is now available on YouTube youtube.com/live/eXb23-r... Please ask questions in the comment section for Chloe. Hope you enjoy it!
youtube.com
"Cracking the Code of Checkpoint Toxicity Mechanisms" by Dr. Chloe Villani
YouTube video by GLOBAL IMMUNOTALKS
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Science Magazine @science.org · 25/09/2026
New results in #ScienceSignaling reveal that the T cell adaptor protein PAG supports the function of #TCell immune synapses by connecting with actin, suggesting that it could offer a target to improve #immunotherapy in patients that show poor responses. scim.ag/3V1ilCa
scim.ag
PAG supports T cell immune synapse function by binding to actin
A plasma membrane adaptor protein supports cytotoxic T cell function by connecting with the actin network.
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The Journal of Immunology @jimmunol.bsky.social · 25/09/2026
Researchers investigated whether MHC-I and MHC-II antigen presentation and the presence of endogenous cDC1s contribute to the efficacy of adjuvant-activated, tumor antigen–loaded cDC1 vaccines. See what they found in The JI: ow.ly/FZ8J50ZQ9K9.
Characterization and functional evaluation of WT, MHC-IKO, and MHC-IIKO cDC1s. Reference scRNA-seq cells are displayed as dots, and bulk RNA-seq samples are overlaid as shapes, corresponding to individual genotypes, as indicated.
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Journal of Experimental Medicine @jem.org · 24/09/2026
Functional heterogeneity and plasticity in naïve #CD8 #Tcells drive superior effector and memory responses. New study from Yamato Sajiki, Koichi Araki @arakilab.bsky.social and colleagues @cincyresearch.bsky.social: rupress.org/jem/article/... #LymphocyteBiology #InfectiousDisease #HostDefense
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Joe Sabatino @jsabatino37.bsky.social · 24/09/2026
Immune signatures of common exposures through co-occurrence of T-cell receptors in tens of thousands of donors www.frontiersin.org/journals/imm...
frontiersin.org
Frontiers | Immune signatures of common exposures through co-occurrence of T-cell receptors in tens of thousands of donors
BackgroundMemory T cells are records of clonal expansion from prior immune exposures such as infections, vaccines and chronic diseases. Some of the receptors...
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Waggoner Lab @labwaggoner.bsky.social · 24/09/2026
Targeting ZMYND8 unleashes IL-2 signalling to override T cell exhaustion @nature.com @stjuderesearch.bsky.social www.nature.com/articles/s41...
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bioRxiv Immunology @biorxiv-immuno.bsky.social · 24/09/2026
Tumor-versus-non-tumor T cell enrichment supported by single-cell and spatial phenotyping enables antigen-agnostic prioritization of candidate tumor-reactive TCRs www.biorxiv.org/content/10.64898/20…
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sigtrans.bsky.social @sigtrans.bsky.social · 25/09/2026
Abstract submission is still possible until September 30! Here is the link to registration and submission:https://sigtrans.de/en/meeting-2026 @kkubatzky.bsky.social @bastianschirmer.bsky.social @sjoerdvanwijk.bsky.social @dgfi-yi.bsky.social
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Ali Seleit @aliseleit.bsky.social · 22/09/2026
Check out the preprint for more experiments and details. If you are interested in having the line please get in touch with Evo-Devo-Tempo Lab or Aulehla Lab. Huge thanks to everyone involved 🙏 @embldbunit.bsky.social @cibss.bsky.social @biologyunifreiburg.bsky.social @dfg.de
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Andrew Straw @andrewstraw.bsky.social · 04/09/2026
We are hiring! Come join us in the Straw Lab at the @biologyunifreiburg.bsky.social . Seeking a scientist to work on the neural and computational mechanisms of visual navigation in honey bees. uni-freiburg.de/en/job/00005...
Bee trajectories in agricultural landscape and two photon microscope for in-vivo calcium activity imaging.
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International Union of Immunological Societies @iuis-online.bsky.social · 23/09/2026
🔬 One week out: Victor Sojo (University of Melbourne) on leadership for professionals. Sep 29, 10pm UTC (4pm Mexico City, 7pm NY, +1d 8am Melbourne). Free on YouTube, no registration. 🌎 loom.ly/5a6qB9s #ImmunologyWithoutBorders
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sfb1160.bsky.social @sfb1160.bsky.social · 22/09/2026
📢 Final call for registration! Join us at the CRC 1160 International #Symposium “IMPAIRED IMMUNITY: From Immunopathology to Immune Reconstitution” (8–10 October 2026, #UniversityofFreiburg). Connect with international experts, and be part of the #ScientificExchange. Secure the final spots now!
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