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Prof Danny Altmann

@daltmann.bsky.social
13K followers 550 following 387 posts

Professor of Immunology, Imperial College London. Editor of OUP Oxford Open Immunology. Co-author - Penguin Long Covid Handbook. Discusses: Covid-19, Long Covid, T cells, immunogenetics and HLA, respiratory infection, science policy, arboviruses, C19th lit

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Prof Danny Altmann @daltmann.bsky.social · 17/09/2026
Who were the Denisovans? Rich trove of fossils and tools paints new picture www.nature.com/articles/d41...
nature.com
Who were the Denisovans? Rich trove of fossils and tools paints new picture
Objects found in a cave in southwestern China suggest that these enigmatic ancient humans were accomplished hunters.
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Prof Danny Altmann @daltmann.bsky.social · 11/09/2026
New clues suggest how destructive immune cells wreak havoc in the brain | Science | AAAS www.science.org/content/arti...
science.org
New clues suggest how destructive immune cells wreak havoc in the brain
Study in mice strengthens T cells’ ties to neurodegenerative conditions like Alzheimer’s
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Prof Danny Altmann @daltmann.bsky.social · 20/08/2026
First-of-its-kind narcolepsy drug opens door to new therapies for the brain www.nature.com/articles/d41...
nature.com
First-of-its-kind narcolepsy drug opens door to new therapies for the brain
The drug, called Orzeyful, takes aim at the root cause of the sleep disorder rather than at its symptoms.
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Prof Danny Altmann @daltmann.bsky.social · 20/08/2026
NIH proposes major revamp of how it scores research grant proposals www.nature.com/articles/d41...
nature.com
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Department of Infectious Disease @imperialinfect.bsky.social · 18/08/2026
How does the immune system keep up with an ever-changing viral world? 🦠 In @nature.com, Prof Rosemary Boyton & @daltmann.bsky.social explore how SARS-CoV-2 research revealed that optimal protection balances immune memory with new variant-specific antibodies. www.nature.com/articles/s41...
nature.com
Immune imprinting in a changing world - Nature Immunology
Research on SARS-CoV-2 shows that effective immunity can arise from a balance between recalling existing immune memory and generating new variant-specific antibodies, with important implications for…
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Department of Immunology and Inflammation @imperialimmuno.bsky.social · 18/08/2026
How does the immune system keep up with an ever-changing viral world? 🦠 In @nature.com, Prof Rosemary Boyton & @daltmann.bsky.social explore how SARS-CoV-2 research revealed that optimal protection balances immune memory with new variant-specific antibodies. www.nature.com/articles/s41...
nature.com
Immune imprinting in a changing world - Nature Immunology
Research on SARS-CoV-2 shows that effective immunity can arise from a balance between recalling existing immune memory and generating new variant-specific antibodies, with important implications for…
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MRC Laboratory of Medical Sciences @mrc-lms.bsky.social · 04/08/2026
New research published today in Nature Genetics uses a technique called mini-Capture Hi-C to map 3D DNA folding in rare ILC3 immune cells, linking 100+ genes to immune disease risk in this cell type 🧬
lms.mrc.ac.uk
Mapping the 3D genome in rare immune cells reveals new genes linked with autoimmune disease risk
Researchers from the MRC Laboratory of Medical Sciences (LMS) and Imperial College London, in collaboration with centres in Europe and the USA, have uncovered new genes linked to autoimmune conditions...
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Department of Immunology and Inflammation @imperialimmuno.bsky.social · 16/06/2026
Scientists have mapped the most comprehensive blood proteome of lupus to date.🩸 The study has revealed new biomarkers and molecular patterns that could enable more personalised treatments for lupus.👇 www.imperial.ac.uk/news/article...
imperial.ac.uk
Large-scale proteomics study reveals subgroups of lupus, paving the way for precision medicine
Scientists have created the most comprehensive map of the blood proteome in systemic lupus erythematosus (SLE or ‘lupus’) to date. The fi...
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Imperial College London @imperialcollegeldn.bsky.social · 18/06/2026
First in the UK, second in the world! We’ve retained our QS World University Ranking for the third year in a row! 🎉 This success is thanks to every single member of Imperial’s community, as we work together to make a meaningful difference in the world.
Imperial 
For the 3rd year running
2nd in the world
1st in the UK and Europe
QS World University Rankings 2027
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Faber Books @faberbooks.bsky.social · 12/08/2026
Barbara Kingsolver will be appearing digitally at this year's #CheltLitFest (9 - 18 October 2026) to discuss her landmark new novel, Partita. The full festival programme is out now, tickets on sale 3 September. www.cheltenhamfestivals.org/events/barba...
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Prof Danny Altmann @daltmann.bsky.social · 12/08/2026
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Prof Danny Altmann @daltmann.bsky.social · 06/08/2026
COVID can wake up a slew of dormant viruses inside you www.nature.com/articles/d41...
nature.com
COVID can wake up a slew of dormant viruses inside you
Reactivation of typically harmless anelloviruses, in particular, seems to be linked with developing long COVID, study finds.
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Prof Danny Altmann @daltmann.bsky.social · 05/08/2026
Obituary: Susumu Tonegawa, Japan’s first Nobel prizewinner in physiology or medicine www.nature.com/articles/d41...
nature.com
Obituary: Susumu Tonegawa, Japan’s first Nobel prizewinner in physiology or medicine
Fearless molecular biologist who revealed the workings of antibodies and memories.
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Prof Danny Altmann @daltmann.bsky.social · 04/08/2026
Very kind - thanks
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Prof Sheena Cruickshank @sheencr.bsky.social · 30/07/2026
Hear hear although in UK still much to do regarding tackling inequalities to address changes in north versus south in longevity
theguardian.com
The US public is fed up with RFK Jr. To really ‘make America healthy again’, it should look to Europe | Devi Sridhar
Americans are dying younger than Europeans, despite being the wealthiest people on the planet. Wellness fads won’t change that, says public health expert Devi Sridhar
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Prof Danny Altmann @daltmann.bsky.social · 30/07/2026
How mosquitoes are conquering the world — in four charts www.nature.com/articles/d41...
nature.com
How mosquitoes are conquering the world — in four charts
Mosquito-borne diseases are breaking records as climate change and other human influences allow the insects to expand their range.
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Prof Danny Altmann @daltmann.bsky.social · 22/07/2026
Call to predoctoral researchers: Introducing the Robin Weiss Science Writing Prize - celebrating creativity in science academic.oup.com/ooim/article...
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Prof Danny Altmann @daltmann.bsky.social · 09/07/2026
AI-predicted spatial transcriptomics unlocks breast cancer biomarkers from pathology: Cell www.cell.com/cell/fulltex...
cell.com
AI-predicted spatial transcriptomics unlocks breast cancer biomarkers from pathology
Path2Space predicts spatial gene expression directly from histopathology, enabling low-cost, large-scale characterization of the tumor microenvironment. The inferred spatial breast cancer landscapes r...
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Prof Danny Altmann @daltmann.bsky.social · 09/07/2026
Europe must learn from America’s assault on science academic.oup.com/eurpub/artic...
academic.oup.com
Europe must learn from America’s assault on science
In June 2026, several prominent diabetes researchers, including Steven Kahn, editor-in-chief of Diabetes Care, were removed by police from the annual meeti
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Prof Danny Altmann @daltmann.bsky.social · 07/07/2026
Global, regional, and national burden of tuberculosis and multidrug-resistant tuberculosis by HIV status, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023 - The Lancet Infectious Diseases www.thelancet.com/journals/lan...
thelancet.com
Global, regional, and national burden of tuberculosis and multidrug-resistant tuberculosis by HIV status, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023
Global progress towards WHO End TB targets is disparate and fragile. Although many regions achieved meaningful gains, others have stagnated in recent years. The complexity of TB prevention is amplifie...
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Prof Danny Altmann @daltmann.bsky.social · 02/07/2026
I study World Cup penalty shoot-outs: they say a lot about the psychology of performance under pressure www.nature.com/articles/d41...
nature.com
I study World Cup penalty shoot-outs: they say a lot about the psychology of performance under pressure
Football's most nail-biting feature can reveal ways for everyone to manage stressful situations better.
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Prof Danny Altmann @daltmann.bsky.social · 01/07/2026
And thanks to AMS for a super day of lectures and family celebration
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Prof Danny Altmann @daltmann.bsky.social · 26/06/2026
Why were mysterious ancient humans found in an African cave all female? | Science | AAAS www.science.org/content/arti...
science.org
Why were mysterious ancient humans found in an African cave all female?
Analysis of fossil proteins deepens mystery of the enigmatic Homo naledi
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Prof Danny Altmann @daltmann.bsky.social · 20/06/2026
US to stop funding HIV programmes in South Africa
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Stefan Marciniak @profmarciniak.bsky.social · 18/06/2026
Wonderful news! #VaccinesWork Cervical cancer deaths fall to zero in young women given vaccine www.bbc.co.uk/news/article...
bbc.co.uk
Cervical cancer deaths fall to zero in young women given vaccine
A new study finds that hundreds of lives have been saved since school-age girls were offered the HPV jab in 2008.
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Prof Danny Altmann @daltmann.bsky.social · 13/05/2026
Calling all students with a research interest in any area of infection/immunity! We're looking for great science writing. The Robin Weiss Prize is to commemorate an inspirational, creative scientist who was highly gifted in writing accessible, readable science. Details here: lnkd.in/eYAHHkT7
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Prof Danny Altmann @daltmann.bsky.social · 18/06/2026
HPV jab means ‘close to zero’ chance of cervical cancer death before 30 www.thetimes.com/article/6e58...
thetimes.com
HPV jab means ‘close to zero’ chance of cervical cancer death before 30
There were no deaths from the disease among women aged 20 to 24 from 2020-2024, according to the research
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Prof Danny Altmann @daltmann.bsky.social · 05/06/2026
www.nature.com/articles/s41... - performed 7776 parallel selection experiments to identify neutralising Ab resistance mutations in 15 primary isolates spanning global HIV-1 genetic diversity - offers a rationale for selecting bnAb combinations most likely to achieve treatment success
nature.com
Diverse paths to broadly neutralizing antibody escape among HIV-1 strains - Nature Microbiology
This study shows that HIV-1 resistance to broadly neutralizing antibodies (bnAbs) in clinical development can develop easily and could compromise their use. Nevertheless, it also identifies bnAb combi...
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Prof Danny Altmann @daltmann.bsky.social · 04/06/2026
Another red alert for American science | Science www.science.org/doi/10.1126/...
science.org
Another red alert for American science
Although research has bipartisan support in the US Congress, and trust in science is above 75% across the country, the Trump administration seems as determined as ever to mortally wound the nation’s s...
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Elizabeth Jacobs, PhD @elizabethjacobs.bsky.social · 28/05/2026
Jay Bhattacharya has been a constant critic of the CDC and of public health strategies to protect the public from infectious disease. After mass firings of expert staff, he’s now looking for untrained volunteers to screen airport passengers for Ebola symptoms. A lot could go wrong with this.
abcnews.com
CDC asks staff to volunteer to help with Ebola screenings at airports amid DRC outbreak
The CDC sent an "urgent request" to staff to help screen passengers coming from Central Africa for any potential signs of Ebola illness.
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Prof Danny Altmann @daltmann.bsky.social · 28/05/2026
Hard-to-detect mutations explain how common autoimmune diseases arise www.nature.com/articles/d41...
nature.com
Hard-to-detect mutations explain how common autoimmune diseases arise
An old theory gains fresh support from advanced DNA sequencing, which can detect rare mutations in B cells from people with autoimmune thyroid conditions.
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Prof Danny Altmann @daltmann.bsky.social · 28/05/2026
Hit a lab project glitch? Thinking about your thesis title like a storyteller can help you focus www.nature.com/articles/d41...
nature.com
Hit a lab project glitch? Thinking about your thesis title like a storyteller can help you focus
Cell biologist and crime novelist Frances Brodsky says writing fiction has taught her perseverance and improved her manuscripts.
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The Skylark @theskylark.bsky.social · 23/05/2026
🧵
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Prof Gavin Yamey MD MPH @gavinyamey.bsky.social · 23/05/2026
In this light, it is rather fascinating to read this quote from Jay Bhattacharya, from before when he became the person in charge of outbreak control (CDC Director) instituting extreme measures beyond what public health experts recommend: “The ideology of the [Covid] lockdowns was that…..” 1/n
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Prof Danny Altmann @daltmann.bsky.social · 23/05/2026
@listentotimesradio.bsky.social asked me to discuss #Ebola response and vaccine timelines. Had to mention that when there’s an outbreak like this we all imagine it’s like a Thunderbirds episode - International Rescue/WHO will appear and make it ok. But…1/2
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Prof Danny Altmann @daltmann.bsky.social · 22/05/2026
Honoured to be in such distinguished company
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Jon Cohen @cohenjon.bsky.social · 19/05/2026
www.science.org/content/arti...
science.org
Scientists play catch-up to startling Ebola outbreak
Testing, sequencing, and clinical trial efforts spring to life as Bundibugyo virus spreads
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Prof Danny Altmann @daltmann.bsky.social · 14/05/2026
www.nature.com/articles/s41...
nature.com
Faecalibacterium prausnitzii enzyme reprograms PD-L1 trafficking and sensitizes colorectal cancer to immunotherapy in mice - Nature Microbiology
Phosphoribosyl pyrophosphate synthetase from Faecalibacterium prausnitzii inhibits PD-L1 trafficking to boost anti-tumour immunity and potentiate anti-PD-1 immune checkpoint inhibitor therapy during c...
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Prof Danny Altmann @daltmann.bsky.social · 14/05/2026
www.nature.com/articles/s41... 'Genome-wide analyses of EBVread+ identified strong associations at the major histocompatibility complex (MHC), including 54 independent human leukocyte antigen (HLA) alleles of MHC classes I and II, and at 27 genomic regions outside MHC'
nature.com
Host control of persistent Epstein–Barr virus infection - Nature
Using blood-based genome sequence data, non-genetic and genetic factors associated with control of Epstein–Barr virus during persistent infection are reported.
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Prof Danny Altmann @daltmann.bsky.social · 13/05/2026
Correct link here: academic.oup.com/ooim/pages/r...
academic.oup.com
The Oxford Open Immunology ‘Robin Weiss Science Writing Prize’
Oxford Open Immunology is pleased to announce the launch of the Robin Weiss Science Writing Prize, a new international award recognising outstanding science wri
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Prof Danny Altmann @daltmann.bsky.social · 13/05/2026
Calling all students with a research interest in any area of infection/immunity! We're looking for great science writing. The Robin Weiss Prize is to commemorate an inspirational, creative scientist who was highly gifted in writing accessible, readable science. Details here: lnkd.in/eYAHHkT7
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Prof Danny Altmann @daltmann.bsky.social · 12/05/2026
BMJ meta-analysis: "evidence does not support causal associations between aluminium adjuvanted vaccines and serious or long term health outcomes"
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Prof Danny Altmann @daltmann.bsky.social · 07/05/2026
The impact of sex on the immune system explored at the single-cell level: The American Journal of Human Genetics www.cell.com/ajhg/fulltex...
cell.com
The impact of sex on the immune system explored at the single-cell level
Yazar et al. characterized sex-based immune differences at single-cell resolution using sex-differential expression (differentially expressed genes [DEGs]) and sex-stratified expression quantitative l...
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Prof Danny Altmann @daltmann.bsky.social · 07/05/2026
Induction of broadly neutralizing HIV antibodies by a two-step mechanism informs vaccine design | Science www.science.org/doi/10.1126/...
science.org
Induction of broadly neutralizing HIV antibodies by a two-step mechanism informs vaccine design
A major obstacle confronting HIV-1 vaccine and cure research is the lack of an outbred animal model for rapid and consistent induction of broadly neutralizing antibodies (bNAbs). We designed an epitop...
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Eric Feigl-Ding @drericding.bsky.social · 05/05/2026
🛑FDA officials have blocked publication of several studies supporting the safety of widely used vaccines against Covid-19 and shingles, HHS confirmed. Gift🎁 link www.nytimes.com/2026/05/05/us/politics/fda-covid-vaccine-studies.html?unlocked_article_code=1.gFA.3_7D.zhKWilYsjCzs&smid=nytcore-ios-share
nytimes.com
F.D.A. Blocked Publication of Research Finding Covid and Shingles Vaccines Were Safe
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Eric Topol @erictopol.bsky.social · 05/05/2026
Yes again. Last week CDC. Now FDA. Blocking evidence of vaccine safety. www.nytimes.com/2026/05/05/u...
nytimes.com
F.D.A. Blocked Publication of Research Finding Covid and Shingles Vaccines Were Safe
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The New York Times @nytimes.com · 05/05/2026
Breaking News: The FDA has blocked publication of research that found widely used Covid-19 and shingles vaccines were safe.
nyti.ms
F.D.A. Blocked Publication of Research Finding Covid and Shingles Vaccines Were Safe
The agency’s scientists and data contractors reviewed millions of patient records for studies that were pulled back before release.
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Prof Danny Altmann @daltmann.bsky.social · 30/04/2026
CDC communication undermines trust in vaccines | Science www.science.org/doi/10.1126/...
science.org
CDC communication undermines trust in vaccines
Uncertainty-based framing raises doubt, lowers vaccination intentions, and boosts science denial
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Prof Danny Altmann @daltmann.bsky.social · 30/04/2026
Delivering an immune therapy into tumours instead of intravenously reduces adverse effects www.nature.com/articles/d41...
nature.com
Delivering an immune therapy into tumours instead of intravenously reduces adverse effects
Severe adverse immune-related events were less frequent when treatment was injected directly into tumours.
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Prof Danny Altmann @daltmann.bsky.social · 28/04/2026
www.nature.com/articles/s41... Interest now in potent anti-CD20 approaches across lupus and other settings.....
nature.com
Positive results for obinutuzumab in SLE phase III trial - Nature Reviews Rheumatology
In the placebo-controlled phase III ALLEGORY trial, treatment with obinutuzumab reduced disease activity in adults with systemic lupus erythematosus over 52 weeks.
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