Immune-mediated pathology as a consequence of impaired immune reactions (IMPATH)

In this study, we report that microbiota depletion exacerbates acute graft-versus-host disease in the central nervous system, driven by microglial activati

Here, the authors apply a standardized system, called TXsystem, to transplant wild mouse gut microbiota into SPF mice, developing “TXwildlings” mice that stably retain natural microbiota and human-lik...

Laboratory mice housed under specific pathogen–free (SPF) conditions are the standard model in biomedical research. However, experiments with a particular inbred mouse strain performed in different la...

Here, the authors apply a standardized system, called TXsystem, to transplant wild mouse gut microbiota into SPF mice, developing “TXwildlings” mice that stably retain natural microbiota and human-lik...