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#SingleCell preprints

@prepub-singlecell.bsky.social
743 followers 1 following 7.4K posts

feeds: biorxiv, medrxiv, arxiv.q-bio, arxiv.cs, arxiv.math, Research Square regex: '(single(- )(cell|nuclei)|s[cn]RNA-seq)' If you have suggestions, please get in contact with @willmacnair :)

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#SingleCell preprints @prepub-singlecell.bsky.social · 2h
Pervasive Somatic Mutations in NF1 Drive Cell Type and Spatially Specific Clonal Selection in Neurofibromatosis #SingleCell 🧪🧬🖥️ www.biorxiv.org/content/10.64898/20…
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#SingleCell preprints @prepub-singlecell.bsky.social · 2h
CHACAM: a cell-cell interaction-guided hierarchical attention model for high-precision cell identity annotation of scRNA-seq data in early C. elegans embryogenesis #SingleCell 🧪🧬🖥️ www.biorxiv.org/content/10.64898/20…
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#SingleCell preprints @prepub-singlecell.bsky.social · 2h
CycloCross: Adversarial single-cell RNA-seq data translation across species #SingleCell 🧪🧬🖥️ www.biorxiv.org/content/10.64898/20…
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#SingleCell preprints @prepub-singlecell.bsky.social · 2h
Stochastic Flow Map for Count Data #SingleCell 🧪🧬🖥️ arxiv.org/abs/2609.23290
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#SingleCell preprints @prepub-singlecell.bsky.social · 2h
Prototype Guided Post-pretraining for Single-Cell Representation Learning #SingleCell 🧪🧬🖥️ arxiv.org/abs/2605.07938
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#SingleCell preprints @prepub-singlecell.bsky.social · 2h
scTrilemma: Balancing Identity, Invariance, and Fidelity in Single-Cell Representation Learning #SingleCell 🧪🧬🖥️ arxiv.org/abs/2609.38840
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#SingleCell preprints @prepub-singlecell.bsky.social · 2h
Moment-based approximation of cell and face integrals in THINC/QQ reconstruction on unstructured grids #SingleCell 🧪🧬🖥️ arxiv.org/abs/2609.38215
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#SingleCell preprints @prepub-singlecell.bsky.social · 2h
CellMSA: Context Modeling for Single-Cell Representation Learning #SingleCell 🧪🧬🖥️ arxiv.org/abs/2609.38908
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#SingleCell preprints @prepub-singlecell.bsky.social · 2h
Single-cell transcriptomics reveals life cycle and cell cycle gene expression dynamics during in vitro growth of two Leishmania species #SingleCell 🧪🧬🖥️ www.biorxiv.org/content/10.64898/20…
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#SingleCell preprints @prepub-singlecell.bsky.social · 8h
Weakly-Supervised Gated Attention Multiple Instance Learning for Multi-Center Cervical Cytology Slide Triage #SingleCell 🧪🧬🖥️ www.medrxiv.org/content/10.64898/20…
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#SingleCell preprints @prepub-singlecell.bsky.social · 8h
Protocol for Single-Cell Patch-Proteomics: identify specific proteins associated with electrophysiological properties from individual neurons #SingleCell 🧪🧬🖥️ www.biorxiv.org/content/10.64898/20…
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#SingleCell preprints @prepub-singlecell.bsky.social · 8h
Spinal microglia are dispensable for the development of opioid-induced hyperalgesia #SingleCell 🧪🧬🖥️ www.biorxiv.org/content/10.64898/20…
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#SingleCell preprints @prepub-singlecell.bsky.social · 8h
ProxiNet transfers spatially learned cellular proximity to dissociated single-cell transcriptomes #SingleCell 🧪🧬🖥️ www.biorxiv.org/content/10.64898/20…
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#SingleCell preprints @prepub-singlecell.bsky.social · 11h
THE MICROANATOMY OF INTRACRANIAL HUMAN THROMBI BY SINGLE NUCLEI TRANSCRIPTOMICS #SingleCell 🧪🧬🖥️ www.biorxiv.org/content/10.64898/20…
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#SingleCell preprints @prepub-singlecell.bsky.social · 11h
Age-Dependent Effects of Macrophage Derived Cathelicidin Antimicrobial Peptide on Bone Fracture Repair #SingleCell 🧪🧬🖥️ www.biorxiv.org/content/10.64898/20…
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#SingleCell preprints @prepub-singlecell.bsky.social · 11h
Desmoglein-1 coordinates cell proliferation and actin dynamics to promote epidermal morphogenesis. #SingleCell 🧪🧬🖥️ www.biorxiv.org/content/10.64898/20…
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#SingleCell preprints @prepub-singlecell.bsky.social · 11h
Cell-of-origin shapes tumor subtype in BRCA1-associated triple-negative breast cancer #SingleCell 🧪🧬🖥️ www.biorxiv.org/content/10.64898/20…
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#SingleCell preprints @prepub-singlecell.bsky.social · 11h
Single-Cell Omics to Uncover Cell-Type-Specific Gene Regulatory Networks Driving Mucilage Production in Specialized Roots #SingleCell 🧪🧬🖥️ www.biorxiv.org/content/10.64898/20…
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#SingleCell preprints @prepub-singlecell.bsky.social · 11h
The Metabolic Organ Clock: A Computable Framework Linking Cell-Lineage Architecture to Emergent Organ Bioenergetics #SingleCell 🧪🧬🖥️ www.biorxiv.org/content/10.64898/20…
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#SingleCell preprints @prepub-singlecell.bsky.social · 11h
Chikungunya Virus Infection of Monocytes Generates a Persistent Macrophage Reservoir That Promotes IFN-π/IL-27-STAT1- and NF-κB-Driven Chronic Arthritis #SingleCell 🧪🧬🖥️ www.biorxiv.org/content/10.64898/20…
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#SingleCell preprints @prepub-singlecell.bsky.social · 14h
Integration of Multidimensional Genetic and Single- Cell Analyses to Identify Potential Drug Targets and a Clinical Risk Prediction Model for Cervical Cancer #SingleCell 🧪🧬🖥️ www.researchsquare.com/article/rs-1…
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#SingleCell preprints @prepub-singlecell.bsky.social · 14h
PDCD10 loss is associated with inflammatory and barrier-related endothelial remodeling in cerebral cavernous malformation #SingleCell 🧪🧬🖥️ www.researchsquare.com/article/rs-1…
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#SingleCell preprints @prepub-singlecell.bsky.social · 14h
Single-cell mapping of the endocannabinoid system in breast cancer reveals distributed expression and ECS-NK correlations that track immune composition #SingleCell 🧪🧬🖥️ www.researchsquare.com/article/rs-1…
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#SingleCell preprints @prepub-singlecell.bsky.social · 14h
Divergent PML and Nucleolar Body Programs Distinguish Protected from Vulnerable Neurons in FTLD-TDP #SingleCell 🧪🧬🖥️ www.researchsquare.com/article/rs-1…
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#SingleCell preprints @prepub-singlecell.bsky.social · 14h
Baseline immune transcriptional signatures predict checkpoint blockade response in triple-negative breast cancer #SingleCell 🧪🧬🖥️ www.researchsquare.com/article/rs-1…
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#SingleCell preprints @prepub-singlecell.bsky.social · 17h
RNA splicing factor mutations drive myeloid neoplasm oncogenesis through protein complex poisoning #SingleCell 🧪🧬🖥️ www.biorxiv.org/content/10.64898/20…
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#SingleCell preprints @prepub-singlecell.bsky.social · 17h
Endothelial AMBRA1 loss contributes to vascular dysregulation facilitating metastatic progression in early-stage melanoma #SingleCell 🧪🧬🖥️ www.biorxiv.org/content/10.64898/20…
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#SingleCell preprints @prepub-singlecell.bsky.social · 17h
Dual inhibition of p38α MAPK and Casein kinase δ/ϵ as a novel treatment strategy for AR-independent and taxane-resistant advanced prostate cancer #SingleCell 🧪🧬🖥️ www.biorxiv.org/content/10.64898/20…
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#SingleCell preprints @prepub-singlecell.bsky.social · 17h
Spatially resolved transcriptomics of poplar reveals tissue organization across shoot-associated organs #SingleCell 🧪🧬🖥️ www.biorxiv.org/content/10.64898/20…
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#SingleCell preprints @prepub-singlecell.bsky.social · 20h
Single-cell transcriptomic prioritization of SQLE and functional validation of SQLE inhibition in colorectal cancer cells #SingleCell 🧪🧬🖥️ www.researchsquare.com/article/rs-1…
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#SingleCell preprints @prepub-singlecell.bsky.social · 20h
Gene flux shapes diversity and evolution of the ancient 17q21.31 inversion polymorphism #SingleCell 🧪🧬🖥️ www.biorxiv.org/content/10.64898/20…
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#SingleCell preprints @prepub-singlecell.bsky.social · 20h
Accurate and scalable demultiplexing of single-cell RNA sequencing using BEACON #SingleCell 🧪🧬🖥️ www.biorxiv.org/content/10.64898/20…
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#SingleCell preprints @prepub-singlecell.bsky.social · 23h
An Efficient Machine Learning Approach for Degradation Forecasting in AEM Water Electrolysis #SingleCell 🧪🧬🖥️ arxiv.org/abs/2609.37941
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#SingleCell preprints @prepub-singlecell.bsky.social · 23h
CancerZigZag: Iterative Seed-Anchored Diffusion for Generative Modeling of Single-Cell State Transitions #SingleCell 🧪🧬🖥️ arxiv.org/abs/2609.37735
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#SingleCell preprints @prepub-singlecell.bsky.social · 23h
Stochastic gradient descent on the epigenetic landscape: a unified framework for cellular plasticity, tumor heterogeneity, and the asymptotic irrelevance of fitness #SingleCell 🧪🧬🖥️ arxiv.org/abs/2609.37703
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#SingleCell preprints @prepub-singlecell.bsky.social · 23h
Gel-Confined Rolling-Circle Amplification Enables Sensitive Single-Cell Proteoform Analysis #SingleCell 🧪🧬🖥️ arxiv.org/abs/2609.36251
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#SingleCell preprints @prepub-singlecell.bsky.social · 23h
Mapping the response of primary human chondrocytes to an osteoarthritis-relevant stimulus by single-cell RNA sequencing #SingleCell 🧪🧬🖥️ www.biorxiv.org/content/10.64898/20…
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#SingleCell preprints @prepub-singlecell.bsky.social · 23h
Single-cell profiling resolves gain- and loss-of-function mechanisms in CASR to advance mechanism-aware variant classification #SingleCell 🧪🧬🖥️ www.biorxiv.org/content/10.64898/20…
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#SingleCell preprints @prepub-singlecell.bsky.social · 23h
Integrated transcriptomic analysis identifies Paternally Expressed Gene 10 as a novel candidate biomarker associated with aggressive features in liposarcoma #SingleCell 🧪🧬🖥️ www.biorxiv.org/content/10.64898/20…
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#SingleCell preprints @prepub-singlecell.bsky.social · 30/09/2026
Towards Scalable Context-Aware Single-Cell Spatial Transcriptomics Prediction from Histology Images #SingleCell 🧪🧬🖥️ arxiv.org/abs/2609.36429
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#SingleCell preprints @prepub-singlecell.bsky.social · 30/09/2026
Cerebral microthrombi promote focal Cav-1-dependent blood-brain barrier impairment, triggering neuroinflammation and neuronal damage after traumatic brain injury #SingleCell 🧪🧬🖥️ www.biorxiv.org/content/10.64898/20…
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#SingleCell preprints @prepub-singlecell.bsky.social · 30/09/2026
MOD-scTWAS: Leveraging gene co-expression for single-cell transcriptome-wide association studies #SingleCell 🧪🧬🖥️ www.biorxiv.org/content/10.64898/20…
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#SingleCell preprints @prepub-singlecell.bsky.social · 30/09/2026
ScProteoAgent enables natural-language-driven single-cell proteomics analysis and interpretation #SingleCell 🧪🧬🖥️ www.biorxiv.org/content/10.64898/20…
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#SingleCell preprints @prepub-singlecell.bsky.social · 29/09/2026
Utilizing single-cell data for per-cell type eQTL mapping in the human pancreas #SingleCell 🧪🧬🖥️ www.biorxiv.org/content/10.64898/20…
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#SingleCell preprints @prepub-singlecell.bsky.social · 29/09/2026
DECIPHER integrates disentangled representation learning and prototype-based cell-type deconvolution across molecular modalities #SingleCell 🧪🧬🖥️ www.biorxiv.org/content/10.64898/20…
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#SingleCell preprints @prepub-singlecell.bsky.social · 29/09/2026
The Venification of the Artery: Insights from Single-Cell Transcriptomics of a Porcine Arteriovenous Fistula Model #SingleCell 🧪🧬🖥️ www.biorxiv.org/content/10.64898/20…
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#SingleCell preprints @prepub-singlecell.bsky.social · 29/09/2026
An FEV-Associated Metastasis-Initiating-Like State Linked to Tumor Cell Plasticity and Immune Niche Remodeling in Prostate Cancer #SingleCell 🧪🧬🖥️ www.biorxiv.org/content/10.64898/20…
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#SingleCell preprints @prepub-singlecell.bsky.social · 29/09/2026
Nailpolish: Reference-free UMI deduplication and consensus read generation #SingleCell 🧪🧬🖥️ www.biorxiv.org/content/10.64898/20…
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#SingleCell preprints @prepub-singlecell.bsky.social · 29/09/2026
Distinct synovial fluid B-cell differentiation and activation profiles in rheumatoid arthritis #SingleCell 🧪🧬🖥️ www.biorxiv.org/content/10.64898/20…
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#SingleCell preprints @prepub-singlecell.bsky.social · 29/09/2026
Inferring cascade drivers of VEXAS syndrome by a causal machine learning tool CauNagi #SingleCell 🧪🧬🖥️ www.biorxiv.org/content/10.64898/20…
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