iiinova — where your digital self keeps evolving

Kamphorst LAB @kamphorstlab.bsky.social · 12/01/2026

NY state friends, please do this today! The Governor’s State of the State is tomorrow, January 13 at 1:00 PM. We are hopeful she will announce the Empire Biomedical Research Institute (EBRI). Email the Governor and your Reps! actionnetwork.org/letters/supp...

actionnetwork.org

Support the Empire Biomedical Research Institute (EBRI)

Tell New York Governor Hochul and your state legislators to support including the Empire Biomedical Research Institute in the 2027 Executive Budget. This is an urgent matter relating to funding life-s...

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David Rooney @david-rooney.bsky.social · 02/01/2026

Starting off the year with a glorious encounter between two Brazilian screen queens: Fernanda Montenegro, the unforgettable star of CENTRAL STATION, meets Kleber Mendonça Filho discovery Tânia Maria, a pistol in THE SECRET AGENT as Dona Sebastiana. Love this so much.

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NY-CURES @nycures.bsky.social · 04/09/2025

🚀 NY-CURES Launch — Championing State-Wide Investment in Science! 🚀 Our new coalition advocates for sustained public support of New York’s vibrant biomedical research ecosystem — creating cures, economic gains & strengthening communities. Sign up. Stay informed. Join the movement: www.nycures.org/

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Kamphorst LAB @kamphorstlab.bsky.social · 27/08/2025

Excited to head to Japan in November to present at the CSHA meeting on Immunoreceptor Signaling and Therapeutic Applications. Abstract deadline is next week! www.csh-asia.org?content/1343

csh-asia.org

WELCOME-Meetings-Cold Spring Harbor Asia

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Ian Parish @ianparish.bsky.social · 13/08/2025

It was a privilege and a pleasure for both myself and @menezesnmaria.bsky.social‬ to preview a great upcoming article in @cp-immunity.bsky.social‬ by @kamphorstlab.bsky.social‬ showing an unexpected inhibitory role for ICOS in exhausted CD8+ T cells. www.cell.com/immunity/abs...

cell.com

The high (I)COSt of costimulation for exhausted T cells

ICOS agonists are being investigated for cancer immunotherapy based on the idea that they will reinvigorate exhausted CD8+ T cell anti-cancer immunity. Humblin et al. unexpectedly find the opposite—th...

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Elizabeth Warren @warren.senate.gov · 05/08/2025

BREAKING NEWS: a government watchdog confirmed the Trump administration is breaking the law by blocking NIH funds. How many kids with cancer or grandmas with Alzheimer’s have to get closer to death while crucial research is stalled? Trump must end this illegal funding freeze.

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Kamphorst LAB @kamphorstlab.bsky.social · 08/07/2025

Our paper is out! Check out this beautiful story where we uncovered that the costimulatory molecule ICOS is detrimental for PD-1+ CD8 T cells. Sustained ICOS signaling reduces memory-like features of progenitor exhausted CD8 T cells in chronic viral infection and liver cancer.

urldefense.proofpoint.com

The costimulatory molecule ICOS limits memory-like properties and function of exhausted PD-1+CD8+ T cells

Understanding regulation of progenitor exhausted CD8+ T (Tpex) cell differentiation is important for immunotherapies. Humblin et al. report that sustained ICOS costimulation is detrimental to PD-1+CD8...

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Denis Wirtz @deniswirtz.bsky.social · 06/03/2025

These are extremely challenging times for early-career faculty. Here is my office's small contribution to make their hard and important work a bit easier: Download our curated and comprehensive database of funding opportunities for early-career faculty. Here: research.jhu.edu/rdt/funding-...

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Eric Topol @erictopol.bsky.social · 02/03/2025

By itself, this is certainly not the most important issue we're confronting right now. But it's emblematic of the pervasive, destructive, anti-science efforts. Gift link www.nytimes.com/2025/02/26/c...

nytimes.com

She Lobbied for a Carcinogen. Now She’s at the E.P.A., Approving New Chemicals. (Gift Article)

Lynn Dekleva, who recently took a senior role at the agency, once led an aggressive effort by industry to block regulations on formaldehyde.

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Kamphorst LAB @kamphorstlab.bsky.social · 26/02/2025

I am sure a lot more science programs will have to make these tough decisions

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Thiago Carvalho @cyrilpedia.bsky.social · 26/02/2025

'In 2024, a budget cut of €900m shocked the scientific community. More recently, additional amendments to this budget proposed further cuts of €630m, along with an extra €534m reduction to the France 2030 program. These cuts threaten not only basic research but also higher education'

journals.biologists.com

The importance of delivering Recherche d'Avenir – research for the future

In recent years, several European countries, including France, have reduced their investment in scientific research, with biomedical research taking a significant hit. The primary casualty is basic re...

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Zachary Brennan @zacharybrennan.bsky.social · 26/02/2025

We are too! DM me or find me on Signal at zacharybrennan.20

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Elizabeth Warren @warren.senate.gov · 14/02/2025

Donald Trump and Elon Musk’s idea of efficiency is stopping research on curing cancer.

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Kamphorst LAB @kamphorstlab.bsky.social · 13/02/2025

March is still a long time from now. We need to stop the bleeding. Talk to your patients. Reach out to your patient advocates and community scientist - call your representatives! Make some noise.

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Kamphorst LAB @kamphorstlab.bsky.social · 12/02/2025

In my lab, we analyze patient samples and develop preclinical models to understand why some patients respond to immunotherpies and others don't. We write grants to support our research. Only 9%, really the top, are funded. But now, NCI/NIH tare not awarding grants even to top scores.

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Dave Levitan @davelevitan.bsky.social · 12/02/2025

Internal NIH guidance updated yesterday. Just canceling stuff each day from here on out I guess, pending new guidance. Killing science off both slowly and incredibly rapidly.

Effective February 10:

NIH Federal Advisory Committee meeting notices to the Office of the Federal Registare are now on hold. This affects NIH's ability to move forward with National Advisory Council/Board meetings that were previously noticed as having open and closed sessions and with Scientific Review Group (study sections and Special Emphasis Panels) meetings and Boards of Scientific Counselors that had not yet been noticed with a Federal Register Notice. As such, NIH will cancel those meetings on a day-by-day basis until additional guidance is received. Scientific Review Group meetings and Boards of Scientific Counselors that were previously noticed are moving forward.

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Jeremy Berg @jeremymberg.bsky.social · 11/02/2025

ATTENTION If anyone has received a NoA after the "pause", please DM me with information about the mechanism and institute or center. THANK YOU

media.tenor.com

a cartoon character says " just let me know "

ALT: a cartoon character says " just let me know "

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ACIR @acir-org.bsky.social · 11/02/2025

The deadline to submit an abstract for a poster presentation is Feb 20. Register now 👉 hubs.la/Q034zC0H0 #KSCancerImmune25

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Thanh Neville, MD, MSHS @thanh-neville.bsky.social · 02/02/2025

So the first year of one our #NIH grants ended on 1/31 and we have not received the Notice of Award for year 2. I'm so confused now--is there an NIH freeze or not? Wasn't it blocked by a judge? Has anyone else received a NOA since this debacle? #academicsky #medsky

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E John Wherry @ejohnwherry.bsky.social · 08/02/2025

YES. Need to say this loudly and often! This 2.46x is also the short-term ROI. Long-term ROI (more difficult to estimate) may ~10x. Highest for any gov't spending. And the source of discoveries necessary for all new drugs (industry important too but without NIH funded science there's no foundation)

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Miguel Reina-Campos @reinacampos.bsky.social · 09/02/2025

First time calling politicians - it felt GOOD! Empowering - might call them again tomorrow, and the day after - get out there! this 5calls website will tell you who to call and provide a draft script #science will #prevail. 5calls.org/issue/nih-ns...

5calls.org

Save NIH and NSF Research Funding ⭑ 5 Calls

On February 7, the Trump administration moved to cut billions of dollars in funding from the National Institutes of Health (NIH) and National Science …

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Shruti Naik @drshrutinaik.bsky.social · 08/02/2025

The loss of AMERICAN science will have ripple effects on jobs and economic growth. At the same time China and other countries are investing heavily in science @schumer.senate.gov @nadler.house.gov

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Kamphorst LAB @kamphorstlab.bsky.social · 07/02/2025

@altnih4science.bsky.social Are study sections and council meetings happening at NIH this week?

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Cooper Battle @chbattle.com · 05/02/2025

Extremely disappointed to see HHMI decide to kill their Inclusive Excellence program, including terminating the current IE3 awards to over a hundred institutions effective this year in the middle of a 6-year grant. I was hoping HHMI (and other private funders) would continue to lead the way.

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Maddy Jalbert @maddyjalbert.bsky.social · 31/01/2025

I am one of these NSF postdocs. NSF has frozen everyone’s access to their salaries and research stipends (that were already awarded) with no information about when they might be expected to be unfrozen. It still appears like we are expected to continue doing our work though.

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Sinai Immuno @sinaiimmuno.bsky.social · 28/01/2025

Immunology will be for everyone, everywhere, everyday, from driving foundational research to reaping the benefits for health. 🌎 Immunoschool 2025 is open for anyone looking to learn more about key immunotherapy advances over the last decade. FREE TO REGISTER: www.eventbrite.com/e/internatio...

eventbrite.com

International Course of Immunotherapy March 10-12, 2025

Eventbrite - Precision Immunology Institute at the Icahn School of Medicine presents International Course of Immunotherapy March 10-12, 2025 - Monday, March 10, 2025 | Wednesday, March 12, 2025 - Find...

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Thiago Carvalho @cyrilpedia.bsky.social · 16/01/2025

"Contrary to current approaches involving rigorous documentation and standardization, we postulate that increasing species diversity can improve microbiota stability and mouse physiology, enhancing robustness, reproducibility, and experimental validity." www.cell.com/trends/immun...

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Kamphorst LAB @kamphorstlab.bsky.social · 09/01/2025

Super excited to be presenting our work at this great meeting!

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American Association for Cancer Research (AACR) @theaacr.bsky.social · 08/01/2025

The inaugural AACR IO Conference on Discovery and Innovation in Cancer Immunology takes place February 23-26 in Los Angeles. Learn why Dr. Antoni Ribas says #AACRIO25 is “the must-attend immuno-oncology event of the year." www.aacr.org/about-the-aa... #AACRStories

aacr.org

AACR IO: Revolutionizing Treatment through Immunotherapy

The AACR’s immuno-oncology meeting in Los Angeles, Feb. 23-26, 2025, brings together the leading experts in immunotherapy to accelerate progress in cancer science and medicine.

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