iiinova — where your digital self keeps evolving

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Christophe 🔬 Leterrier @christlet.bsky.social · 18/09/2026

Questions about the recently announced Small World in Motion winner @healthcare.nikon.com

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Kevin A. Scott, PhD @sculpturatus.bsky.social · 17/09/2026

found at ucsf

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Sebastian Munck @sebastianmunck.bsky.social · 10/09/2026

Last call for our interuniversity course in advanced microscope - application deadline: 14 September www.flandersbioimaging.org/icalm26

flandersbioimaging.org

iCALM26 | Fbiv23

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Reese Richardson @reeserichardson.bsky.social · 25/08/2026

A massive update: At least ~15 companies~ are selling scientists antibodies using faked validation data. We've documented 18,000+ manipulated images on 17,000+ products sold by leading laboratory suppliers including Thermo Fisher, Abcam, Santa Cruz Biotechnology, Millipore Sigma and Bio-Techne. 1/🧵

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Jeffrey van Haren @jeffreyharen.bsky.social · 13/08/2026

Some pictures of the solar eclipse yesterday. Taken in Rotterdam, the Netherlands

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Jeffrey van Haren @jeffreyharen.bsky.social · 27/06/2026

Large hailstones here in Rotterdam, a moment ago..

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Sasha | Kai Dao 🔬 @kaidaoscience.bsky.social · 19/06/2026

8 hours. That’s all fish need to heal wounds 🐟⏱️ Why are they so fast compared to humans? I break down the science of rapid regeneration in a microscopy story 🔬 Watch here: youtu.be/Mt9f61adaP0 #FluorescenceFriday #Microscopy

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Jeffrey van Haren @jeffreyharen.bsky.social · 19/06/2026

Beautiful shelf cloud above Rotterdam!

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Henry De Belly @henrydebelly.bsky.social · 10/06/2026

Very excited to be sharing our new paper, just out in Nature Cell Biology! The big question we investigate: How do migrating cells put their front 🔴 and back 🔵 in the right place?

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Nikolai Slavov @slavov-n.bsky.social · 07/06/2026

95% of papers reporting antibody-based analysis of p16-INK4a used antibodies for an unrelated protein, p16-ARC. Despite using the wrong antibody, authors reported the expected results: > Genetic perturbations of p16-INK4a altered reported p16-ARC levels. 1/

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Reese Richardson @reeserichardson.bsky.social · 05/06/2026

The Thermo Fisher situation keeps getting worse. We've now collected 450+ problematic images presented as verification data in TF's antibody catalog. This includes: 🖌️ Dozens more images with duplications or painting 🖨️ Hundreds of blots that all share the same background (behold slideshow below)

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Ali Shaib @alishaib.bsky.social · 01/06/2026

Hello #world, meet 1,000× Expansion Microscopy. A small gel would grow to the size of an Olympic swimming pool, while amino-acid-scale distances become visible with ordinary light microscopy. Led by Helena Hu from @eboyden3.bsky.social's lab, in collab with us. Story: www.biorxiv.org/content/10.6...

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Journal of Cell Biology @jcb.org · 01/06/2026

Our June issue is here! rupress.org/jcb/issue/22... The cover shows a maximum intensity projection from a confocal image stack showing an angiogenic sprout emerging from an engineered microvessel. From @lakynm.bsky.social et al. of the Matthew Kutys lab: rupress.org/jcb/article/... #Cytoskeleton

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Richard Sever @richardsever.bsky.social · 30/05/2026

"Hypothesis generation: pretty good...data analysis: a super power...executing experiments: not so much" AI can help at every stage of the research cycle. Jonah Cool from @anthropic.com discuss the benefits of integrating frontier models and potential concerns youtu.be/sz1vQyBzSgw?...

youtu.be

Interview with: Jonah Cool

YouTube video by CSHL Leading Strand

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Torsten Wittmann @microtubule.bsky.social · 22/05/2026

A day in the life of a growing hiPSC spheroid expressing endogenously mStayGold-tagged histone 3.3 for #FluorescenceFriday and the #Snouty aficionados. 28 hours (and >50,000 exposures) later and they are still going! Home-brewed volume projection.

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Nico Stuurman @nicostuurman.bsky.social · 21/05/2026

I'll be writing a few posts about new features in Micro-Manager. If you are interested in those, please follow @micro-manager.bsky.social.

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Eugene Katrukha 🇺🇦 @ekatrukha.bsky.social · 21/05/2026

New release of #BigVolumeBrowser (0.1.1) adds support for (multiscale) OME-Zarr (thanks to libraries from @bogovicj.bsky.social, Stefan Hahmann, Vladimir Ulman). And midi gizmo navigation (from @herrsaalfeld.bsky.social ), shown below.

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Julia Lazzari-Dean @jlazzaridean.bsky.social · 12/05/2026

We invented “triplet tumbling microscopy” (TTM) to track protein-protein interactions in living cells! Tag your protein with GFP and see it interact with *untagged* binding partners www.biorxiv.org/content/10.6...

A cartoon overview of triplet tumbling microscopy, comparing data from bound and unbound samples.

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epithelial mechanics fan club @epimechfc.bsky.social · 03/05/2026

How do epithelial cells integrate mechanical and biochemical signals to control their behavior? I am @ronjahoutekamer.bsky.social, and in this thread, I’ll show you how force transduction connects to biochemical signaling, and how it activates ERK by inducing biochemical ligand shedding.

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Stefan Oehlers @oehlerslab.org · 02/04/2026

Really cool #zebrafish paper 🧪 from Bart Weijts & Catherine Robin (Hubrecht): starts with the basic question of are those superbright kdrl/fli1a positive cells (that we've all seen in the vascular Tg lines) something special? Yes! They're lumenal macrophages www.nature.com/articles/s41...

nature.com

Blood vessel-resident macrophages safeguard blood and vessel integrity in zebrafish - Nature Immunology

Robin and colleagues describe a population of blood vessel-resident macrophages that function within the vasculature to maintain vascular and blood homeostasis in zebrafish and identify a conserved po...

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Eugene Katrukha 🇺🇦 @ekatrukha.bsky.social · 31/03/2026

The new release of #BigVolumeBrowser (0.1.0) finally adds animation render functionality to it, plus some other navigation improvements and bug fixes. Here is a movie I've made for the microtubule network (via ExM) in different cell types. Contact me if you want it for educational/research purposes.

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Pablo J. Sáez @pjsaez.bsky.social · 16/03/2026

This is why we love #CalciumSignaling Look how mechanical damage triggers long range Ca2+ waves in this plant !! By @annalisabellandi.bsky.social, who is now around here ;) Full www.science.org/doi/10.1126/... @science.org #microscopy #cell #mechanobiology 🧪🔬

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c0nc0rdance @c0nc0rdance.bsky.social · 10/03/2026

Let's learn about horseshoe crabs (family Limulidae). In a few nights, a female can lay over 100,000 transparent eggs. The fertilized eggs hatch within 2-4 weeks, having gone through 4 embryonic molts within the egg. During this time, they're sometimes called "trilobite larvae."

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Buzz Baum @buzzbaum.bsky.social · 25/01/2026

Using micropatterning & thousands of hours on the microscope @manuelthery.bsky.social and the #CytoMorphoLab reimagined the Musée D’Orsay. Accompanied by an orchestra and poet, their images transported us into the cellular universe. I remembered why I am a cell biologist. All of this is in us. Wow!

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Prasad Jallepalli, MD, PhD @prasad.bsky.social · 18/01/2026

essential reading — we are at the edge of a collapse in the global order that made us safe and prosperous for nearly 80 years

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Jeffrey van Haren @jeffreyharen.bsky.social · 04/01/2026

lots of snow at Schiphol airport today!

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Dan 🐟 C @zebrafish007.bsky.social · 02/12/2025

Exciting new #Zebrafish research from the #WeinsteinLab, led by Jong Park! “Specialized gas-exchange endothelium of the zebrafish gill” — www.biorxiv.org/content/10.6... Amazing to see red blood cells moving through the gills! Don’t forget to check out the supplemental movies ;-)

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Journal of Cell Biology @jcb.org · 02/12/2025

Lerche, Mathieu, @johannaivaska.bsky.social @ivaskalab.bsky.social et al. reveal that newly synthesized #integrins can bypass the Golgi to be actively delivered to specific plasma membrane regions, where they enhance cell protrusion and #adhesion. rupress.org/jcb/article/...

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Luca @lucagalletti.bsky.social · 06/11/2025

It mourns not for its own fate, but for that of the world and all its beauty, flitting through the cosmos, blown into the void like a light blue wildflower trampled by the night's frost.

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International Society of Developmental Biology @isdb.bsky.social · 31/10/2025

In the spirit 👻 of Freaky Friday 🎃, here is a beautiful yet eery video of zebrafish retina development showing horizontal cells (🔵) finding their way out of the crowded amacrine (🟠) layer to settle beneath the photoreceptors. Happy #Halloween! 🎥: PhD student Rae Wong from the @nordenlab.bsky.social

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Ardem Patapoutian @ardemp.bskyverified.social · 14/10/2025

During these uncertain times, I’m very happy to see that my institution, @scripps.edu has an open tenure-track Assistant Professor position. Any field in Chemistry or Biology is welcome. I’d especially love to see fellow neuroscientists apply. Please repost! apply.interfolio.com/174756

apply.interfolio.com

Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio

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Manuel Thery @manuelthery.bsky.social · 14/10/2025

We hire! The CytoMorpho Lab is looking for an engineer with a background in cell and molecular biology to join our team in Paris. This is a 18-month contract position, but we're open to exploring long-term opportunities. More details here: cytomorpholab.com/index.php/jo...

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Anh Hoang Le, PhD 🏳️‍🌈🏴󠁧󠁢󠁳󠁣󠁴󠁿🇻🇳 @anhhle2702.bsky.social · 14/10/2025

I found these immune cells just finished mitosis but their midbody is still yet to be resolved. How cool? If you zoom in to the midbody, you can see its classical shape just like in the textbooks. I love these little details.

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Alfred Millett-Sikking @amsikking.bsky.social · 13/10/2025

The future of High-Content Imaging has arrived. -> Ultra-fast 3D imaging of multi-well plates at high resolution using an air objective! See previous posts and the new miOPM preprint for details: doi.org/10.1101/2025...

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Torsten Wittmann @microtubule.bsky.social · 08/10/2025

Playing around with how to represent volume in #Snouty light sheet data. Here is a dividing hiPSC with endogenously tagged histone in all three orthogonal projections. Bluer is further away. If anything, it distracts from politics.

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Arif Ashraf @aribidopsis.bsky.social · 01/10/2025

🍀🔬 MSL10 is a high-sensitivity mechanosensor in the tactile sense of the Venus flytrap @natcomms.nature.com from Toyota lab. www.nature.com/articles/s41...

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Daniel J. Cohen (Princeton) @djcohen.bsky.social · 17/09/2025

SCHEPHERD--the bioelectric cell herding platform built for YOU. Single cells, monolayers, organoids--this herds them all + new tricks. Plz try it-- we will *give* you parts! Teaser here of a steering a single cell. GS Yubin Lin's lifeblood with J. Yodh on piano; Celeste R. and Paul K. Thread 1/N

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Alex Naka @gottapatchemall.bsky.social · 18/09/2025

My group at Science has been running a big campaign to engineer new channelrhodopsins. Excited to share the first results from it today: a suite of highly sensitive new opsins. We call them "WAChRs". Everyday indoor office lighting is enough to activate them pretty strongly.

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Ronja Houtekamer @ronjahoutekamer.bsky.social · 13/09/2025

A bit delayed, but excited to still share our latest paper, showing that intercellular forces transduced by E-cadherin activate EGFR-ERK signaling in epithelia by inducing EGFR ligand shedding! Mechanical and biochemical signals can act together within a single, linear cascade! tinyurl.com/mr9mj9j2

tinyurl.com

E-cadherin mechanotransduction activates EGFR-ERK signaling in epithelial monolayers by inducing ADAM-mediated ligand shedding

Epithelial stretching promotes the release of EGF receptor ligands that stimulate ERK activation.

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Daniel Kronauer @danielkronauer.bsky.social · 05/09/2025

Ant reproduction is getting weirder and weirder. Here’s the latest: queens of a Mediterranean harvester ant mate with males from a different species and then lay eggs that clonally inherit those males’ genome. I.e., they lay eggs that develop into a different species. 🤯

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Jeremy Baskin @jeremybaskin.bsky.social · 31/08/2025

I’ve already highlighted this landmark #lipidtime paper by @nadlerlab.bsky.social & colleagues, but ICYMI, do read André’s thread — this study is a huge leap forward in understanding the logic of intracellular lipid flux & is a phenomenal example of #chembio probes 🤝 quantitative imaging 🤝 modeling!

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Jeffrey van Haren @jeffreyharen.bsky.social · 30/08/2025

Nice! A song about one of my favorite fluorescent proteins! mStayGold!

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Harmit Singh Malik @harmitmalik.bsky.social · 03/08/2025

It's reassuring to know that letting your beverages dry out in your workplace coffee mugs and turning them into disgusting gobs of sticky goo is an ancient and time-honored practice. www.smithsonianmag.com/smart-news/s...

smithsonianmag.com

Scientists Found Sticky Goo Inside a 2,500-Year-Old Jar. Seventy Years Later, They Finally Know What It Is

By studying the mysterious substance's chemical makeup, scientists determined the pot was once full of honey

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