Reposted by Pablo J. SáezElena Scarpa & The Squeezable Cells Lab @squeezycellslab.bsky.social · 29/09/2026Call for abstracts: the UK Cell Motility Club is back! Keynote speaker : Caren Norden 🐠 Fantastic early career talk opportunity and lovely community! Register here: forms.cloud.microsoft/e/zNNCMfD5jF 086
Reposted by Pablo J. SáezFocalPlane @focalplane.bsky.social · 8hWhile we’ve heard that watching cell blebs (like watching larva lamps) can be relaxing, we think that @ankita13jha.bsky.social’s talk from our #CellMigration webinar will leave you feeling excited about #science & running to your #microscope! Full video @ focalplane.biologists.com/2026/09/25/f... 0124
Reposted by Pablo J. SáezSaez-Rodriguez Group @saezlab.bsky.social · 29/09/2026Happy to see the peer-reviewed version of SpaCEy now out: 📄 Published paper: www.nature.com/articles/s41... 💻 Code: github.com/saezlab/SpaCEy 1114
Reposted by Pablo J. SáezMark Peifer (He, him) @peiferlabunc.bsky.social · 28/09/2026Are you looking for a postdoc exploring the cell biology of development, defining how cells change shape and move? Do you want to develop a research program & teaching skills preparing you for a position at a college or small University? Our new NIH grant will support those goals 1/n Please share 5104102
Reposted by Pablo J. SáezIsabel Stötzel @isabel-stoetzel.bsky.social · 25/09/2026What a fantastic visitor! Thanks Pablo @pjsaez.bsky.social @cellcommlab.bsky.social for visiting Turku (organised by @mattilalab.bsky.social )! Especially, it was a pleasure to hear your experiences and thoughts during the career/science session. Thanks for taking the time and sharing your opinion! 393
Reposted by Pablo J. SáezFocalPlane @focalplane.bsky.social · 25/09/2026ICYMI: the recording of our second webinar on emergent models and quantitative analysis of cell migration is now available. 🔬🎥Check it out to see talks from @ankita13jha.bsky.social, @raphclement.bsky.social and @katrinavelle.bsky.social focalplane.biologists.com/2026/09/25/f...focalplane.biologists.comFocalPlane features... cell migration recordings with Ankita Jha, Raphaël Clément and Katrina Velle - FocalPlaneFocalPlane features... cell migration recordings with Ankita Jha, Raphaël Clément and Katrina Velle - News 0127
Reposted by Pablo J. SáezValeria Venturini @valeriaventurini.bsky.social · 22/09/2026In @pcusachs.bsky.social’s lab at @ibecbarcelona.eu we have a fully founded open PhD position! It’s a very nice working environment & can promise cool mechanobiology🔬🧫 Here all the info ibecbarcelona.eu/predoctoral-...ibecbarcelona.eu 01010
Reposted by Pablo J. SáezJan Lammerding - Lab @lammerdinglab.bsky.social · 21/09/2026Looking for a faculty position combining research in fundamental cell and molecular biology with therapeutic discovery? Join our amazing faculty at the @weillinstitute.bsky.social at Cornell University in Ithaca, New York. academicjobsonline.org/ajo/jobs/32657 Apply by Nov. 15! Please share! 03127
Pablo J. Sáez @pjsaez.bsky.social · 20/09/2026#CellCommunication + #CalciumSignaling What else can you ask for? 020
Pablo J. Sáez @pjsaez.bsky.social · 18/09/2026#Mechanobiology rules! Today, it's not only Chile's independence day🇨🇱😋 ...but also Sara Wickström @sarawickstrom.bsky.social is getting the Körber Prize 👏🏽👏🏽👏🏽 for being a "curiosity's junkie" 😂 Of note, Kate photobombing is top @katemiro.bsky.social @focalplane.bsky.social @koerber-ip.bsky.social 2214
Pablo J. Sáez @pjsaez.bsky.social · 16/09/2026Wanna see blebs dancing & new models of #CellMigration? Join us tomorrow to see the great talks from @ankita13jha.bsky.social, @raphclement.bsky.social & @katrinavelle.bsky.social Thu 17 Sep. at 15:00 BST / 16:00 CEST Register: focalplane.biologists.com/2026/09/03/f... @focalplane.bsky.socialnt.bsky.socialBluesky 1174
Reposted by Pablo J. SáezFocalPlane @focalplane.bsky.social · 15/09/2026Don’t miss the second webinar in our new series on cell migration, featuring talks from @ankita13jha.bsky.social, @raphclement.bsky.social and @katrinavelle.bsky.social. 🗓️Thursday 17 September at 15:00 BST For more info and to register: focalplane.biologists.com/2026/09/03/f...focalplane.biologists.comFocalPlane features... cell migration webinar 2 - FocalPlaneFocalPlane features... cell migration webinar 2 - News 1189
Reposted by Pablo J. SáezSeema Grewal @seemagrewal.bsky.social · 16/09/2026Working on #cellmigration? Join us online tomorrow for the second webinar in our series, hosted by @pjsaez.bsky.social and @valeriaventurini.bsky.social 094
Pablo J. Sáez @pjsaez.bsky.social · 15/09/2026Relieved to remember that after 1 M versions + last minute changes somehow, somewhere there is light @ the end of the tunnel... Grateful for the work of my @cellcommlab.bsky.social Whenever is ready we'll post it to receive comments from the community 😉 Tks 4 existing @biorxivpreprint.bsky.social 🧪🔬 030
Reposted by Pablo J. SáezJournal of Cell Biology @jcb.org · 11/09/2026Gourkanti et al. @neal-lab.bsky.social show that the rhomboid protease Rhbdl2 restrains #macrophage recruitment & wound repair in #zebrafish, positioning Rhbdl2 as a potential brake on macrophage-driven repair rupress.org/jcb/article/... #Migration #motility #Immunology 03914
Reposted by Pablo J. SáezTeresa Rayon @trayon.bsky.social · 12/09/2026‼️ Postdoc position open. We study how protein metabolism controls time. If you’re excited by this question, we’d love to hear from you! We’re looking for a motivated & collaborative researcher with a strong track record. 📅 30 September 2026 📢 Please share Apply here 👇👇babraham.current-vacancies.comPostdoctoral Research Scientist - BabrahamThe lab investigates the molecular mechanisms that control biological timing in mouse and human stem cells (Azzi & Rayon, Curr Opinions 2024; Nakanoh et al., Dev Cell 2026). The central aim of this ex... 14140
Reposted by Pablo J. SáezFocalPlane @focalplane.bsky.social · 10/09/2026📢One week to go! Join us on Thursday 17 September at 15:00 BST (UTC+1) for our webinar on new models for studying cell migration, hosted by @pjsaez.bsky.social & @valeriaventurini.bsky.social. You’ll hear talks from @ankita13jha.bsky.social, @raphclement.bsky.social and @katrinavelle.bsky.social.focalplane.biologists.comFocalPlane features... cell migration webinar 2 - FocalPlaneFocalPlane features... cell migration webinar 2 - News 0136
Reposted by Pablo J. SáezMax-Planck-Gesellschaft @maxplanck.de · 09/09/2026We are hiring! Start at a #MaxPlanckInstitute with your own independent Max Planck Research Group. This position is equivalent to a W2 Professorship at a German university, or Associate Professor internationally. 🔗Apply until October 14th! www.mpg.de/career/max-p... #ScienceCareer #MPRG #TenureTrack 094117
Reposted by Pablo J. SáezTriangle Cytoskeleton Meeting @tricytomeet.bsky.social · 04/09/2026LAST CALL FOR POSTER ABSTRACTS! We are just over 2 weeks away from the 2026 Triangle Cytoskeleton Meeting at the William and Ida Friday Center on Sept. 21st. Submit your abstract by Monday, Sept. 7th for the opportunity to present a poster. Registrations will remain open until Sept. 14th. 101
Reposted by Pablo J. SáezAnh Hoang Le, PhD 🏳️🌈🏴🇻🇳 @anhhle2702.bsky.social · 07/09/2026Very happy to share my postdoc paper is out now in @natcellbio.nature.com titled "Tissue flow acts as a guidance cue for immune cell polarization and directional migration". If you love imaging and immune cells, this is for you! #microscopymonday www.nature.com/articles/s41... A 🧵: 1/n 18392106
Reposted by Pablo J. SáezTamas Nagy @tamasnagy.com · 06/09/2026Even with all the advancements in automated cell tracking getting us to 90%+ accuracy...that's still a lot of broken tracks over long movies! Our brains are pretty good at this so I made Vizsla 🐕, a little @napari.org plugin, to help you fix your tracks manually. 👉 pypi.org/project/napa... 13012
Pablo J. Sáez @pjsaez.bsky.social · 06/09/2026This is why we love #CellMigratuon ! This beautiful story is now out, very interesting role for RhoA and also the cover, Neutrophils on the 'Rho'ad Congrats to all authors, especially to former colleagues and friends Full @science.org www.science.org/doi/10.1126/...science.orgAdaptive motility enables neutrophils to rapidly navigate confined capillariesNeutrophils maintain migration speed in confined capillaries through adaptive actomyosin remodeling. 0235
Reposted by Pablo J. SáezKatrina Velle @katrinavelle.bsky.social · 03/09/2026I'm very excited to be included in this lineup! Thanks @pjsaez.bsky.social and @valeriaventurini.bsky.social for organizing! 0131
Reposted by Pablo J. SáezFocalPlane @focalplane.bsky.social · 03/09/2026We are excited to invite you to the second webinar in our cell migration series. In this webinar, we focus on new models for studying cell migration with talks from @ankita13jha.bsky.social, @raphclement.bsky.social & @katrinavelle.bsky.social. More info⤵️: focalplane.biologists.com/2026/09/03/f... 12518
Pablo J. Sáez @pjsaez.bsky.social · 02/09/2026Another year is gone & I grow old and proud of the work of my team @cellcommlab.bsky.social To celebrate the 6th labversary, we did the best we can do: we submitted...now to cross fingers & to press F5. OK, to celebrate we also had pizza as tradition dictates ;) #CellMigration & pizza lovers 🧪🔬 091
Reposted by Pablo J. SáezCaetano Reis e Sousa @reisesousalab.bsky.social · 19/08/2026Hope you enjoy this short piece, which came out yesterday. Some thoughts I’ve been musing on for a while about why adaptive immunity evolved. Read it for free at rdcu.be/fAO5Prdcu.beWhy adaptive immunity?Nature Reviews Immunology - Adaptive immunity is indispensable to vertebrates, yet most living organisms defend themselves perfectly well without it. Here, I ask why somatically diversified antigen... 34416
Reposted by Pablo J. SáezIsabella Backman @izzybackman.bsky.social · 19/08/2026For @science.org , I wrote about brain-eating amoeba 🦠 and fascinating new research led by @katrinavelle.bsky.social which could help explain how the usually harmless pond-dweller ends up in the brain. www.science.org/content/arti...science.org‘Brain-eating amoeba’ appears to love crawling into narrow spacesClaustrophilic behavior may help Naegleria fowleri find food—and accidentally travel up the human nasal cavity 04012
Pablo J. Sáez @pjsaez.bsky.social · 18/08/2026#cytoskeleton So, there is a small (very small) 9-aa motif that is an evolutionary conserved anchor to actin. It's named: short linear actin filament-binding motif (SFM), and it's *the same* found in LifeAct ! Full: www.nature.com/articles/s41... @natcellbio.nature.com @cellclub.bsky.social 🧪🔬 091
Reposted by Pablo J. SáezIvan Zanoni @lozanzi.bsky.social · 14/08/2026#DAMPsPower!! Excited to share the 💥new 💥 review @ Science Immunology that @marcodigioia & I wrote about the immunological activities played by host-derived oxidized lipids in controlling infections & tumorigenesis! doi.org/10.1126/scii...doi.orgRegulation of inflammation by oxidized lipidsLipids generated by oxidative stress and their effects on immunity and cancer are reviewed. 12514
Reposted by Pablo J. SáezBiozentrum, University of Basel @biozentrum.unibas.ch · 10/08/2026Ready for the next step in your scientific career? Apply now for a fully funded Biozentrum PhD Fellowship and explore a wide range of research fields before choosing your PhD lab. 🧪 Applications for the current call are open until October 18, 2026. More information 👇biozentrum.unibas.chBiozentrum PhD FellowshipsShare your passion for life sciences. If you are talented and highly motivated, want to broaden your horizons and are interested in a wide range of research topics, apply for one of the sought after B... 0910
Reposted by Pablo J. SáezJournal of Cell Science @jcellsci.bsky.social · 05/08/2026We invite you to submit your latest research to our upcoming special issue: Proteostasis. This issue will be coordinated by two of our Academic Editors: Pedro Carvalho and Tamotsu Yoshimori. journals.biologists.com/jcs/pages/pr... 01010
Reposted by Pablo J. SáezJuan Carlos De la Concepcion @delaconcepcionjc.bsky.social · 05/08/2026PLEASE SHARE! New job openings in my lab @zmbp-tuebingen.bsky.social. We have a broad interest into the mechanistic basis of how molecular complexes are rewired during cellular development in plants and during invasion by pathogens. 🌱🍄🔬 See details below 👇 #PlantSciJobs 274105
Reposted by Pablo J. SáezRoyal Microscopical Society @royalmicrosoc.bsky.social · 04/08/2026Booking is OPEN for Frontiers in BioImaging 2026! Sessions will span technical developments in light and electron microscopy, advances in image analysis and data interpretation, and biological applications across scales. Register now: ow.ly/ZN3950Zuj9j 037
Reposted by Pablo J. SáezJulio Alcántara @julioalcante.bsky.social · 05/08/2026In the next session, we will discuss chapter 3 on August 12th, 2026 at 16h CET. @r3rt0.bsky.social @k4tj4.bsky.social www.crowdcast.io/c/brain-in-t...crowdcast.ioReading club: The Brain in Theory by Romain BretteRegister now for Reading club: The Brain in Theory by Romain Brette on crowdcast, scheduled to go live on September 23, 2026, 10:30 AM GMT+2. 132
Reposted by Pablo J. SáezThibaut Brunet @thibautbrunet.bsky.social · 30/07/2026@sbcf.bsky.social can we have the link? 😇 101
Reposted by Pablo J. SáezYanlan Mao @yanlanmao.bsky.social · 30/07/2026This epic paper, which has been a heroic 10 year journey for the lead author, Ricardo Barrientos, is finally out in Cell today! Many thanks to all co-authors, especially Billie Meadowcroft and Andela Saric for their beautiful MD simulations www.cell.com/cell/fulltex...cell.comBasement membrane turnover controls cell shapeBasement membranes are scaffolds of proteins, like collagen, that give organs shape. During development, basement membranes must adapt to the growing organ. We infer how fast the basement membrane ada... 112654
Reposted by Pablo J. SáezUCLA Broad Stem Cell Research Center @uclastemcell.bsky.social · 29/07/2026Watch a muscle fiber take shape. 🔬 This microscopic video captures a muscle cell fusing with a developing muscle fiber, with cell membranes visible in purple and yellow. The Rando Lab uses live-cell imaging to understand how cells coordinate muscle regeneration. Credit: Tamas Nagy/Rando Lab 0123
Reposted by Pablo J. SáezLauren Sumner-Rooney @laurensr.bsky.social · 29/07/2026📢 JOB ALERT! 📢 I am recruiting a 30-month postdoc to work on modelling the vision of trilobites @hfspo.bsky.social ! If you like 3D data, fossils, and functional morphology, this is the one for you! 📆Deadline 27. Aug Pls contact me with any Qs and share widely! www.bristol.ac.uk/jobs/find/de...bristol.ac.ukDetails | Working at Bristol | University of Bristol 28892
Pablo J. Sáez @pjsaez.bsky.social · 29/07/2026Decades ago in 🇨🇱 cellbio meeting immunologist delivers a ppt with 90% immuno and 10% cellbio. Everyone baffled. 1st row sitting senior PI rise the hand: -why did you come to this cellbio meeting? -yeah I wonder the same sometimes (laughs nervously) -I'm not joking, why?! This 👇🏽 is magnificent too 030
Reposted by Pablo J. SáezAIC at Janelia @aicjanelia.bsky.social · 23/07/2026This afternoon's imaging lab at #IALSJanelia is all about subcellular structures, highlighted here by myosin (white) and actin (orange). These membrane ruffles were captured on our lattice light-sheet microscope by @cmhobson.bsky.social 05218
Reposted by Pablo J. SáezRaphaël Clément @raphclement.bsky.social · 22/05/2026Our work on Trichoplax locomotion and mechanosensing capabilities is out now in @currentbiology.bsky.social. Congrats Marvin Leria & all co-authors! authors.elsevier.com/c/1n8Ig3QW8S... 48335
Reposted by Pablo J. SáezJournal of Cell Biology @jcb.org · 20/07/2026Michaud, @andrewgoryachev.bsky.social, von Dassow, @xenresearchcenter.bsky.social et al. identify a versatile cortical pattern-forming circuit based on #Rho, F-#actin, Ect2, & RGA-3/4 rupress.org/jcb/article/... 📕 In "Collective Behaviors and Self-Organization in Cells" rupress.org/jcb/collecti... 07329
Reposted by Pablo J. SáezDanielle Beckman @daniellebeckman.bsky.social · 17/07/2026This is not AI. This is real microscopy! 🔬 An intact gut, rendered transparent and imaged in 3D using light-sheet microscopy! 🤓 Looking inside organs to investigate where pathogens, immune cells, or disease processes may persist. More at: www.nature.com/articles/s41... Happy #FluorescenceFriday! 316538
Reposted by Pablo J. SáezRachel Lee, PhD @scientistrachel.bsky.social · 17/07/2026Microscopy beautifully reveals the dynamic nature of biology but quantifying that motion can be tricky! In the latest paper from @aicjanelia.bsky.social, out now in @jcellsci.bsky.social, we present a tool for measuring amorphous motion: OpticalFlow3D journals.biologists.com/jcs/article/... (1/7)journals.biologists.comOpticalFlow3D – a tool for measuring amorphous motion in three-dimensional fluorescence microscopy imagesSummary: Biological motion can be difficult to define and measure. Optical flow is uniquely suited to this challenge. We provide tools for 3D optical flow and illustrate its use in extracting biologic... 13412
Reposted by Pablo J. SáezHuman Frontier Science Program @hfspo.bsky.social · 09/07/2026What does frontier science look like? 🧪 At #HFSPmtg2026, it spans everything from cell migration and photosynthesis to evolution, plant biology or ocean microbiomes. Different questions. Different approaches. One community exchanging ideas across disciplines! 💪 #HFSP #sts 2145
Reposted by Pablo J. SáezAnh Hoang Le, PhD 🏳️🌈🏴🇻🇳 @anhhle2702.bsky.social · 10/07/2026Another #FluorescenceFriday. When the world is going crazy, I find some peace watching at these myeloid cells (🔴) going about their day. They exist in tissue surrounded by other cells (🔵), and you can see them popping up and down, going in and out of plane as they explore their surrounding. 18320
Reposted by Pablo J. SáezFocalPlane @focalplane.bsky.social · 01/07/2026Bringing together science & art, @manuelthery.bsky.social & the CytoMorpho lab describe their project on how cells adapt their shape to their environment using the Musée d’Orsay as their template! The full performance was presented over two nights at the museum earlier this year. #sciart #cellbiofocalplane.biologists.comLiving Architectures - FocalPlaneLiving Architectures - Case studies 12011
Reposted by Pablo J. SáezJournal of Experimental Medicine @jem.org · 30/06/2026Bile acid retention in efferocytic #macrophages shapes their inflammatory status during #cholangitis. New study from Amirah Al Jawazneh, Imke Liebold, Stephanie Leyk, Lidia Bosurgi (Universitätsklinikum Hamburg Eppendorf) et al.: rupress.org/jem/article/... @pjsaez.bsky.social #inflammation 073
Reposted by Pablo J. SáezRan Blekhman @blekhman.bsky.social · 27/06/2026I wanted to like QED's new 1% preprint ranking. I really did. But the more I looked at the data, the more uncomfortable it made me. Here is my full peer review. open.substack.com/pub/blekhman...open.substack.comMy Peer Review of The 1%I wanted to like QED's new 1% ranking. I don't. 1720888