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Prasad Jallepalli, MD, PhD

@prasad.bsky.social
12K followers 1.5K following 12K posts

Prof & Lab Head in NYC. 100% research: cell division, genome integrity, cancer. Curious to a fault. Also πολύτροπος. Talking here for me alone. I listen to the finest worksong. Like/repost = bookmark/news, not agreement/endorsement.

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Reposted by Prasad Jallepalli, MD, PhD
Maggie Astor @maggieastor.bsky.social · 1h
The 988 suicide prevention hotline's Press 3 option — which provides specialized services to LGBTQ callers — has been restored more than a year after the Trump administration shut it down. Confirmed by HHS and the office of Senator Tammy Baldwin, who led on legislation that forced its restoration
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Reposted by Prasad Jallepalli, MD, PhD
Charlie Warzel @cwarzel.bsky.social · 5h
There is a moment at the very very end of Abdul El-Sayed's podcast with Ezra Klein (book recommendation section) where he talks about the idea of "speaking truth to pain" and this will be staying with me for an extremely long time. www.nytimes.com/2026/09/25/o...
But there’s also something about truth to pain. We talk a lot about truth to power, but I think it’s actually a lot harder to speak truth to pain. I say that as someone who went to medical school, realizing that in a lot of our politics right now, we’ve got to get a lot better at speaking truth to pain if we’re going to get through some of these challenges that we have.

What does “truth to pain” mean?

It’s one thing to look power in the eye and say: You’re wrong about this. But there’s a way in which pain is very difficult to reason with. Because when somebody is in their pain, they’re in their trauma. They see that pain, and they may not see what’s causing it.

I remember just very explicitly being in a trauma ward with a gunshot wound patient and watching this big guy with his hand on his gunshot wound. All the folks are trying to pull his hand off his pain, that point of his gunshot wound, this clear vulnerability.

And this emergency room doctor had the presence of mind to be like: Everyone, stop. And she looks him in the eyes, and she’s like: I get that really hurts, and I’m so sorry that you’re here. You don’t want to be here. We don’t want you to be here. But if you don’t let us fix this, you could die. So I’m going to take your hand, and I’m going to move it off, OK? Because I need to get there so that you can live.

She was speaking truth to pain. He understands he’s at the hospital, he needs care, but he also doesn’t want anybody to touch the wound. Which is a natural thing. And I think it is a really great metaphor for how we think about a lot of these challenges we talked about today.
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Reposted by Prasad Jallepalli, MD, PhD
NPR @npr.org · 3h
The Pentagon made last-minute changes to forms that many overseas U.S. citizens use for absentee voting, removing a category of citizens that Republicans have been pushing to block from voting. n.pr/4iT13Ru
n.pr
Trump officials changed forms for overseas voters amid a GOP push to restrict voting
The Pentagon made last-minute changes to forms that many overseas U.S. citizens use for absentee voting, removing a category of citizens that Republicans have been pushing to block from voting.
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Reposted by Prasad Jallepalli, MD, PhD
TPM @talkingpointsmemo.com · 3h
The proposed bill would also prevent the president from attempting to use a pocket rescission in the future.
talkingpointsmemo.com
Senate Dems Will Attempt to Stop Trump White House’s Latest Illegal Pocket Rescission 
Senate Appropriations Committee Ranking Member Patty Murray (D-WA) and Senate Budget Committee...
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Reposted by Prasad Jallepalli, MD, PhD
Anthony Michael Kreis @anthonymkreis.bsky.social · 29/09/2026
Can’t do student loan relief. Can’t mandate vaccines. Can’t help home owners. Can commit human rights abuses.
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Reposted by Prasad Jallepalli, MD, PhD
Daniel Drezner @dandrezner.bsky.social · 4h
Dear America.gov, Go fuck yourself. Dan
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Reposted by Prasad Jallepalli, MD, PhD
Kathleen Bachynski @bachynski.bsky.social · 5h
“We’re at a period where our molecular understanding is unprecedented,” said Dr. Paul Mischel, a physician scientist at Stanford. “But the infrastructure is really falling apart.” “It’s a problem — it’s a big, big problem,” he added. “People should be really angry.”
nytimes.com
New Cancer Drugs Are Revolutionary. Why Don’t More Patients Get Them?
Targeted gene therapies are highly effective at stopping cancers, but the very abundance of the treatments, plus cost and sluggish change, are hindering access.
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Reposted by Prasad Jallepalli, MD, PhD
Roger Parloff @rparloff.bsky.social · 8h
Queasy vibes at yesterday's en banc DC Cir argument over whether Judge Boasberg can resume fact-finding on potential criminal contempt by AG Blanche, Judge Bove et al. Stated: suspicion of DOJ cover-up; Unstated: role of 3 Trump-appointed colleagues in shutting down inquiry so far. 1/2
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Steve Vladeck @stevevladeck.bsky.social · 6h
Just a reminder that the last time DOJ filed a misconduct complaint against a district judge, it was dismissed in a ruling by Chief Judge Sutton that was all but dripping with contempt (for the government): www.opn.ca6.uscourts.gov/internet/jud...
opn.ca6.uscourts.gov
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Reposted by Prasad Jallepalli, MD, PhD
Roger Parloff @rparloff.bsky.social · 6h
Since briefing was completed in July, the 11th Circuit pushed back oral argument in the case about Judge Cannon's suppression of Jack Smith's Vol 2 five times. Today, for the first time, it moved argument forward. Currently set for week of 11/2/26, instead of week of 1/18/27.
This appeal has been removed from tentative calendar 6 and will be scheduled for oral argument on Monday, November 2, 2026 at 2:00 p.m. in Atlanta, Georgia. A calendar will be issued separately. [25-14507, 26-10674]
Removed from Tentative Calendar
Calendar issued as to cases to be orally argued on 11/02/2026 in Atlanta, Georgia.
Counsel are directed to electronically acknowledge receipt of this calendar by docketing the Calendar Receipt Acknowledged event in ECF (a document upload is not required). [25-14507, 26-10674]
Main Doc
Calendar Issued
Download PDF
Assigned to tentative calendar number 6 in Birmingham during the week of
JANUARY 18, 2027(Please note change of date.). [25-14507, 26-10674] [Entered:
09/21/2026 10:05 AM]
Main Doc
Assigned to Tentative Calendar
Download PDF
Assigned to tentative calendar number 6 in Birmingham during the week of January 11, 2027. [25-14507, 26-10674] [Entered: 09/14/2026 12:51 PM]
Main Doc
Assigned to Tentative Calendar
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Reposted by Prasad Jallepalli, MD, PhD
WildPartyInviteDecliner @ratelimitexceeder.bsky.social · 8h
On the one hand, this person was incredibly naive, to put it lightly. On the other hand, you can see why all the narratives in 2024 about why hispanic voters would really love Trump's mass deportations were not gonna survive contact with reality.
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Greg Sargent @gregsargent.bsky.social · 11h
Something remarkable is happening: James Talarico is running an expansively pro-immigrant campaign in Texas, a state Trump won by 14 points, speaking in Biblical terms about our duty to "the stranger." And it's resonating. That's seismic. 1/ (new piece) newrepublic.com/article/2160...
newrepublic.com
In Texas, Something Seismic Is Happening—and It’s All Trump’s Fault
Thanks to the economy and ICE, Trump has lost Texas Latinos. And James Talarico is developing a humane pro-immigrant message that’s resonating—even in this ultra-Trumpy state.
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The New York Times @nytimes.com · 11h
A clash in the cockpit of a commercial jet flying from Dubai to Tel Aviv on Wednesday caused the plane to plunge near the Saudi-Jordanian border before passengers on the flight intervened to subdue the attacker, according to accounts from people on board.
nyti.ms
Passengers on Flight From Dubai to Israel Intervene After Clash Between Pilots: Live Updates
The pilot and co-pilot of a flight from Dubai to Tel Aviv were hospitalized with injuries after the plane made an emergency landing in Saudi Arabia, Saudi officials said. The episode raised fears of a hijacking, though it was not immediately clear what had prompted the clash.
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Carl Quintanilla @carlquintanilla.bsky.social · 11h
GATES: “.. I almost can’t believe you’re asking that.” @ezraklein.bsky.social @nytimes.com www.nytimes.com/2026/09/29/o...
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Dr. Todd Arrington @btarrington.bsky.social · 11h
One year ago today, I got a life-altering phone call: Trump administration demanding my resignation or would fire me as Director of Eisenhower Pres. Library. I had over 27 years of federal service (civilian & military). This was my wife’s Facebook post about it. I married so out of my league.
This color image shows a long Facebook post about a man fired from his civil service job by the Trump administration.
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Reposted by Prasad Jallepalli, MD, PhD
Gerry Doyle @mgerrydoyle.bsky.social · 12h
this is being framed as politically risky but at this point in the uk there is almost no one who thinks brexit was a net positive and much hard data confirming how badly it hurt the economy www.bloomberg.com/news/article...
bloomberg.com
Burnham Says Britain Could Rejoin the EU After Next Election
Prime Minister Andy Burnham said he could campaign to take Britain back into the European Union at the next general election, reopening the country’s debate on its relationship with the continent a de...
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Reposted by Prasad Jallepalli, MD, PhD
The Wall Street Journal @wsj.com · 12h
Hedge-fund titan Ken Griffin is donating $2 billion to start a Carnegie Mellon University campus in Miami, part of the largest-ever individual gift toward higher education.
on.wsj.com
Exclusive | Ken Griffin Is Making the Largest Donation to Higher Education in U.S. History
The Citadel CEO’s gift will launch a Carnegie Mellon University campus in Miami.
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Prasad Jallepalli, MD, PhD @prasad.bsky.social · 18h
Incredible stats: * tonight’s 9-0 result is the second shutout in Yankees-Red Sox history (first was in 2025!) * Ben Rice’s 6 RBIs tie the franchise record for a postseason game (1960 World Series Game 3)
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Prasad Jallepalli, MD, PhD @prasad.bsky.social · 19h
HULK SMASH GRAND SLAM
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Reposted by Prasad Jallepalli, MD, PhD
Chemjobber @chemjobber.bsky.social · 19h
One of the things that pleased me to no end as a weirdo guy who is really interested in the military is that, as a part of my other weirdo hobby (ie listing all the available tenure track positions in chemistry in America) that, routinely, I got to list USMA, USNA, USAFA, USCGA and others
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Prasad Jallepalli, MD, PhD @prasad.bsky.social · 19h
if you’re calling it a “second opinion,” you’re practicing medicine without a license or malpractice insurance
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Reposted by Prasad Jallepalli, MD, PhD
Adam Keiper @adamkeiper.com · 20h
lol, amazing sequence
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Reposted by Prasad Jallepalli, MD, PhD
Dustin Volz @dustinvolz.bsky.social · 20h
www.nytimes.com/2026/09/29/u...
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Prasad Jallepalli, MD, PhD @prasad.bsky.social · 20h
BEN RICE HULK SMASH
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Reposted by Prasad Jallepalli, MD, PhD
Flying Mezerkis @bananapantz.bsky.social · 21h
Look at the graph or follow the link. The entire change in fortunes began on February 28th. Dems bottomed out and haven't stopped rising since. GOP recovered for a few weeks to their high, and have barely returned to it since. This must be one of the greatest all-time political blunders.
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Reposted by Prasad Jallepalli, MD, PhD
Jacob T. Levy @jacobtlevy.bsky.social · 21h
wake up babe, new Skynet/ Matrix/ WOPR/ robot apocalypse strategy just bounced: they're going to use the brain-rotted guy in charge of health policy to tell us to all start licking measles homeopathically.
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Reposted by Prasad Jallepalli, MD, PhD
David Corn @davidcorn.bsky.social · 21h
Nothing but super intelligence all around at the White House.
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Prasad Jallepalli, MD, PhD @prasad.bsky.social · 22h
nothing gets me going like playoff baseball fearing the longest and fiercest rivalry of all — Yankees vs Red Sox
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Professa Murray @kalimurray.bsky.social · 22h
Congress has enacted between 40 and 50 distinct public laws that explicitly incorporate the term “artificial intelligence.”
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Reposted by Prasad Jallepalli, MD, PhD
Professa Murray @kalimurray.bsky.social · 22h
There is literally an act called the National Artificial Intelligence Act of 2020 and it contains the standard statutory definition of artificial intelligence.
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Reposted by Prasad Jallepalli, MD, PhD
David W (aka Flex NP) @rnflex.bsky.social · 23h
Full Retatrutide phase 3 obesity data published today. It's gonna take a minute to fill dissect this. The appendix alone has 70 pages of data. Long story short we created a drug that's almost too good. Huge chunks of people stopped or reduced doses from excess weight reductions.
nejm.org
Retatrutide, a Triple Hormone Receptor Agonist, for Treatment of Obesity | NEJM
Retatrutide is a triple-receptor agonist of glucose-dependent insulinotropic polypeptide, glucagon-like peptide-1, and glucagon receptors. In this phase 3, randomized, double-blind trial, we assign...
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Reposted by Prasad Jallepalli, MD, PhD
Justin Hendrix @justinhendrix.bsky.social · 29/09/2026
Plus, the "White House Accord on Super Intelligence: Joint Commitment on Frontier Responsibilities" signed by Trump, Google's Pichai, Anthropic's Amodei, Meta's Zuckerberg, OpenAI's Brockman, XAI's Musk, Nvida's Huang.
In order to build a positive future for the American people and the world, we believe every company is responsible for developing its own technology safely and in a way that builds trust with customers and the public.

This starts with every company that is training and deploying frontier models having robust internal processes and controls to ensure that their technology behaves as intended and that any issues are promptly identified and resolved. Therefore, in addition to any other precautions, we believe each company should implement the following four layers of controls and audits:

(1) Implement robust internal controls to monitor the capabilities and alignment of its models during training and deployment around areas like cybersecurity, biosecurity, and chemical threats, and to ensure that its models do not hack or access technical systems in unintended ways.

(2) Empower an internal team to ensure all of the controls, monitoring, and detection are operating as intended, and that any issues are remediated.

(3) Partner with an independent external auditor or evaluator to carry out independent assessments of whether the controls, monitoring, and detection are operating as intended.

(4) Designate an independent committee of the board of directors to oversee and receive reports from the teams operating the controls and the internal and external auditors and evaluators, as well as to ensure any issues identified are remediated.

Together, these steps will give each company, its customers, and the public confidence that the technology is operating as intended.

The participating companies will meet regularly to establish standards and best practices to improve the safety of their systems.

Over time, it may make sense to codify these steps into laws or regulations. Regardless of whether this is required of companies, we believe that implementing these controls and audits is critical to ensuring a safe future for everyone, and each of our companies are ...Page 2 (signature page)

[signature]
Donald J. Trump
President of the Unites States

[signature]
Sundar Pichai
Google

[signature]
Dario Amodei
Anthropic

[signature]
Mark Zuckerberg
Meta

[signature]
Greg Brockman
OpenAI

[signature]
Elon Musk
XAI

[signature]
Jensen Huang
Nvidia
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Prasad Jallepalli, MD, PhD @prasad.bsky.social · 22h
every day there’s a new breakthrough in stupidity
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Prasad Jallepalli, MD, PhD @prasad.bsky.social · 22h
got to give Seahawks coaching staff and front office credit
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The Editorial Board @editorialboard.bsky.social · 29/09/2026
@adamgurri.liberalcurrents.com: "There is a longer, harder struggle ahead, that cannot be solved with power alone. That is the struggle of living in a society and a liberal democracy that would elect the 'mass deportation' candidate in the first place." www.liberalcurrents.com/editors-note...
liberalcurrents.com
Editor's Notes: Your Local Fascists
We know what to do with Trump and his stooges. The harder question is what to do with the ordinary Americans we will have to live alongside afterwards.
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Hans L’Hoest @hanlho.com · 29/09/2026
This is where they could have mentioned that Huggingface could defend itself from the OpenAI hack exactly because of GLM 5.x as the closed models didn’t allow them..
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Scoiattolo @scarnecchia.net · 29/09/2026
Anthropic is just directly fearmongering about the open weight models that are eating their lunch on price now huh
anthropic.com
GLM-5.3 and the Spread of Advanced Cyber Capabilities
GLM-5.3 can autonomously build end-to-end cyber exploits, but unlike other frontier models, it was released without meaningful safeguards to limit misuse.
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David Kaye @davidakaye.bsky.social · 29/09/2026
reminder that we are talking about this
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Scott MacFarlane @macfarlanenews.bsky.social · 29/09/2026
Jack Smith: “it’s inconceivable to me how you can pardon people who beat police officers… and then vilify the officers”
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David Kaye @davidakaye.bsky.social · 29/09/2026
it's evidently too much to ask the rw justices to consider the irreparable harm to individuals treated to such inhumanity. they are complicit in this criminality. shame on all six of them. and shame on us for having a system that allows this illegality.
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Bill @bill-of-lefts.bsky.social · 29/09/2026
no option but to pack the court
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Don Moynihan @donmoyn.bsky.social · 29/09/2026
And once again, real harms imposed on real people must be set aside until after real damage is done in order to privilege the unproven right of Trump to impose those harms
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Steve Vladeck @stevevladeck.bsky.social · 29/09/2026
#BREAKING: Over dissents from the three Democratic appointees, #SCOTUS grants a stay in the third-country removals case; clears way for Trump admin. to continue removing non-citizens without a full chance to litigate the conditions in those countries (while also taking up the full merits appeal).
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Prasad Jallepalli, MD, PhD @prasad.bsky.social · 29/09/2026
at this point I’m not sure he knows where Kansas City is
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Clay Copper @claycopper.bsky.social · 29/09/2026
I'm going to level with you all. The wokest educators the DoD has on staff are all AD. Civs can't compete with the levels of woke a good AD dude with a few deployments under their belt can level at students.
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Michael "Fallen Coffee Pot of Shadows" Senters the Sigillite:ABD @mikesenters.bsky.social · 29/09/2026
I will say this until I am dead; the average American voter is a consumer first, a citizen second and a global citizen a distant third.
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Helen Kennedy @helenkennedy.com · 29/09/2026
When your big gotcha moment goes so epically wrong that it’s the other party sharing clips of it.
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Bobby Kogan @bbkogan.bsky.social · 29/09/2026
GAO, the agency tasked under the Impoundment Control Act with adjudicating impoundments, says as explicitly as possible the Donald Trump and Russ Vought’s pocket rescission is illegal. “The President may not force the expiration of budget authority Congress has already enacted and did not rescind.”
politico.com
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Sahil Kapur @sahilkapur.bsky.social · 29/09/2026
Susan Collins on how to push back on Trump’s $810 mill rescission: “One of the things that could be done is the GAO could be authorized to sue the administration under the Impoundment & Budget Control Act of 1974. So that's one option. But Congress would have to authorize that.”
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Prasad Jallepalli, MD, PhD @prasad.bsky.social · 29/09/2026
sidehawkeye
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