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NordenLab

@nordenlab.bsky.social
2.4K followers 454 following 103 posts

How do organs form from cells to tissue? Zebrafish and organoids; live imaging; quantitative biology; theory. Comments by Caren Norden

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NordenLab @nordenlab.bsky.social · 18/09/2026
We also finally have a lab picture! Growth in progress … 😉
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NordenLab @nordenlab.bsky.social · 06/09/2026
Wo fing das an, was ist passiert, was hat uns bloss so ruiniert.....
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NordenLab @nordenlab.bsky.social · 04/09/2026
It was a looong June for @dianagm.bsky.social but worth the wait (I think). Check out our new preprint in collaboration with Adolfo Alsina and Guillaume Salbreux (both not here) about what you need or might not need for our two eyes to match. Check it out: www.biorxiv.org/content/10.6...
biorxiv.org
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NordenLab @nordenlab.bsky.social · 24/08/2026
Sharing a scientific session with former PhD student @marija-matejcic.bsky.social and she easily outperforming me was probably one of my best scientific experiences so far ….
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NordenLab @nordenlab.bsky.social · 24/08/2026
Sharing a scientific session with former PhD student @marija-matejcic.bsky.social and she easily outperforming me was probably one of my best scientific experiences so far ….
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NordenLab @nordenlab.bsky.social · 23/08/2026
The reunion before the reunion… sometimes it is scary how fast time moves. What an amazing group of people I had the honor to help train and work with….
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NordenLab @nordenlab.bsky.social · 23/07/2026
I know I am shouting into a void here as the people doing it are not on this platform...Dear applicants, I know what my homepage says, I wrote it. If you want to apply to my lab, please tell me in your own words WHAT you are excited about and why. I will be excited with you and we can discuss...!
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NordenLab @nordenlab.bsky.social · 03/07/2026
And yes, despite the heated debate last week, I came to the conclusion that pre-prints are still the best way to distribute your work early and wide. Score me don't score me, time will show relevance after all.
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NordenLab @nordenlab.bsky.social · 03/07/2026
#2 Close collaboration with @rocha-lab.bsky.social across institutes. @catfigueiredo.bsky.social shows that neurogenic progenitors in the developing retina can respond to cell death with an unexpected self-renewing division. I am sure Mauricio has more to say :-). www.biorxiv.org/content/10.6...
biorxiv.org
Apoptosis-induced self-renewal of neurogenic progenitors safeguards retinal development against extensive cell loss
Developing embryos have a striking ability to buffer external and internal perturbations. A key example of this phenomenon across developing systems is successful organ formation even after substantia...
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NordenLab @nordenlab.bsky.social · 03/07/2026
We are trying for a hattrick this month and two out of three are out: #1 Great work by Margarida Cruz et al. showing that tissue context in addition to cell intrinsic programs can determine migration mode of neurons. Retinal Bipolar Cells as an example. Check it out! www.biorxiv.org/content/10.6...
biorxiv.org
Tissue lamination state switches neuronal translocation from active to passive in the vertebrate retina
Neuronal migration is essential for establishing functional tissue architecture in the developing central nervous system. While cell-intrinsic mechanisms driving neuronal movement have been identified...
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Roberto Mayor Lab @mayorlab.bsky.social · 16/05/2026
PL retweet. Developmental Biology Course (Quintay). More information: biodesarrollo.unab.cl
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NordenLab @nordenlab.bsky.social · 13/05/2026
It also almost starts looking like a lab space 🙂
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NordenLab @nordenlab.bsky.social · 13/05/2026
First lab outing Cambridge edition in the five minutes the sun was shining … decent coffee and to many more
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NordenLab @nordenlab.bsky.social · 01/04/2026
My personal April’s fool I guess: when I was called over to HR in the ‘old school’ I was not aware that they will make me sign into this very important book that supposedly started in 13XX and THIS is what I was wearing… My mum will be so proud she said taking the picture 🤷‍♀️ #thingstolearnincambridge
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NordenLab @nordenlab.bsky.social · 30/03/2026
And it’s a wrap… the end of an era and what an era it was at igc and @gimminstitute.bsky.social. @pdncambridge.bsky.social and @gurdoninstitute.bsky.social here I come. Brace yourselves 😉!
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FocalPlane @focalplane.bsky.social · 11/03/2026
📢New behind the paper story Using the #zebrafish retina as a model, Jaakko Lehtimäki @jalehtimaki.bsky.social, Caren Norden @nordenlab.bsky.social & team dissect multipolar migration in the developing brain. In this post, Jaakko takes us through their research.
focalplane.biologists.com
Spider-like neurons finding their way: signposts for multipolar migration in the developing brain - FocalPlane
Spider-like neurons finding their way: signposts for multipolar migration in the developing brain - News
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NordenLab @nordenlab.bsky.social · 04/02/2026
Check out the tour de force by @jalehtimaki.bsky.social in its final form: www.sciencedirect.com/science/arti... . An elegant combination of transcriptomics, F0 screens and high end imaging unravels the cues that guide cells (here retinal horizontal cells) in an increasingly crowded tissue. #proudPI
sciencedirect.com
Spatiotemporal coordination of Slit-Robo repulsion and neurturin-Gfrα attraction guides multipolar migration during retinal lamination
Multipolar migration is a conserved neuronal migration mode in the developing brain, enabling emerging neurons to navigate in crowded environments and…
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NordenLab @nordenlab.bsky.social · 23/01/2026
We encounter some bureaucratic problems importing our fish...Does anybody have a transgenic zebrafish line that marks the basement membrane/ECM in the UK? Would need to mark optic cup and final eye for our purposes. And/or an ras-GFP/RFP line? Thanks for looking and reposting!
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NordenLab @nordenlab.bsky.social · 08/01/2026
New year celebration of the @nordenlab.bsky.social to great adventures and new beginnings (and a bit the end of an era)
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NordenLab @nordenlab.bsky.social · 23/12/2025
A very sweet gesture by the @gimmfoundation.bsky.social canteen team for the remaining researchers before Christmas. Sofia and her team are just wonderful. Happy holidays!
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NordenLab @nordenlab.bsky.social · 28/11/2025
José João Freitas (not on Bluesky) conducted mysterious and important work during his masters and defended today with the rare grade of 20/20! Well deserved! #proudPI … great things to come from this young man!
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EMBL @embl.org · 27/11/2025
Anthony A. Hyman will become EMBL’s next Director General. He joins EMBL from @mpi-cbg.de in Dresden. He is also Professor of Molecular Biology @tudresden.bsky.social, and was a group leader at EMBL Heidelberg from 1993 to 1999. www.embl.org/news/people-...
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Patricia Ramos @apramos.bsky.social · 26/11/2025
Thank you A. Perez-Ramos and P. Bovolenta for this great perspective on our article about Optic Cup morphogenesis @dev-journal.bsky.social !
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NordenLab @nordenlab.bsky.social · 07/10/2025
In case it was unclear that I have the best lab ever…I do! Just a regular ‘girls night out’ and boy was there singing 😉
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NordenLab @nordenlab.bsky.social · 14/09/2025
Last corrida do Tejo as a resident…for many reasons it did not go very well for me this year but @dianamorales defended the lab honor! It is all about finishing in the end…😉 And a good reason to be back in 2026 and do better!
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NordenLab @nordenlab.bsky.social · 22/08/2025
The Friday second try: After intense work, especially in the last year, this work is finally ready to be seen by the public. Led by @apramos.bsky.social and great collaboration with @carldmodes.bsky.social group especially @liormoneta.bsky.social : www.biorxiv.org/content/10.1...
biorxiv.org
The Optic cup is actively shape programmed by independently patterned apical forces
During morphogenesis, initially flat tissues often must transition into complex 3D shapes, reminiscent of shape-programmable systems in physics and engineering. One key question in developmental biolo...
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Mauricio Rocha @rocha-lab.bsky.social · 22/08/2025
The Company of Biologists Workshops 2027: Excited to share that our workshop concept, "Bridging Scales and Disciplines to Understand Robust Development”, has been selected! 🤩@giuliapaci.bsky.social and I are looking forward to organizing it. Stay tuned for details! @biologists.bsky.social
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NordenLab @nordenlab.bsky.social · 22/08/2025
Look who is here: @carldmodes.bsky.social ! It took a while but I can be persistent....more this afternoon :-)
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NordenLab @nordenlab.bsky.social · 31/07/2025
We had our traditional @nordenlab.bsky.social summer BBQ! This time without BBQ but with Indian food, Murder Mystery (it was Ze) and some real blood in the end (tall people should avoid my house). But overall lots of fun and games. Looking forward doing that in Cambridge in the rain ;-)...
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NordenLab @nordenlab.bsky.social · 25/07/2025
New preprint from the lab showcasing work led by @jalehtimaki.bsky.social on retinal patterning by non-canonically migrating neurons that sense spatiotemporally diverse guidance cues. Full thread about the content done by Jaakko here on Bluesky, check it out! www.biorxiv.org/content/10.1...
biorxiv.org
Spatiotemporal Coordination of Guidance Cues Directs Multipolar Migration During Retinal Lamination
Multipolar migration is a conserved neuronal migration mode in the developing brain, enabling emerging neurons to navigate crowded environments and reach precise laminar positions. Yet how these cells...
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Biomedical Picture of the Day BPoD @bpodaily.bsky.social · 08/07/2025
Crowd Control: The position & shape of cell nuclei influence organ formation (organogenesis) 📹 ‪@lcferme.bsky.social et al @gimmfoundation.bsky.social in @science.org Advances ➡️ bpod.org.uk/archive/2025/7/7 with John Ankers
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NordenLab @nordenlab.bsky.social · 09/06/2025
Congratulations to @marianagil (not on Bluesky) for successfully defending her thesis today. The end of an era of the first batch of people joining the lab in Portugal…thanks to all jury and lab member for making this a memorable day!!!
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NordenLab @nordenlab.bsky.social · 28/05/2025
A long overdue get together to celebrate the arrival of summer. Great company fun conversations, we all learned a lot…😉. Take note that @catfigueiredo.bsky.social has her eyes (well at least one) open! This was the only one out of 12 pictures…her secret super power!
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PDN Cambridge @pdncambridge.bsky.social · 08/05/2025
We are delighted to welcome Dr Caren Norden to PDN as the new Charles Darwin Professor of Animal Embryology. This position plays a vital role in sustaining our thriving community of developmental and reproductive biologists. Read the story in full at www.pdn.cam.ac.uk/news/dr-care... #WomenInSTEM 🧪
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NordenLab @nordenlab.bsky.social · 10/05/2025
The amazing tour de force of the great @lcferme.bsky.social is now out in its final form in @ScienceAdvances (not on Bluesky???). It was hard work and all the conceptual advance was her doing. Check it out: www.science.org/doi/epdf/10....
science.org
Timely neurogenesis drives the transition from nematic to crystalline nuclear packing during retinal morphogenesis
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NordenLab @nordenlab.bsky.social · 08/05/2025
Yes, that is me, for those who did not yet know. This was not planned but I am very happy to go 'home' even though I will miss a lot about Portugal. If you still want to visit, hurry, otherwise see you in Cambridge. If you want to know more contact me directly. www.pdn.cam.ac.uk/news/dr-care...
pdn.cam.ac.uk
Dr Caren Norden appointed Darwin Professor of Animal Embryology at PDN | Department of Physiology, Development and Neuroscience
Dr Caren Norden has been appointed Darwin Professor of Animal Embryology, joining the Department of Physiology, Development and Neuroscience in the School of Biological Sciences, from April 2026. Her ...
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Moritz Treeck @moritztreeck.bsky.social · 10/04/2025
Open call for 3 Group Leader Positions at the newly formed GIMM in Lisbon! Strong core facilites, Science across many disciplines + Sunshine, Beaches and the Atlantic. Link to call here gimm.pt/jobs/open-ca...
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NordenLab @nordenlab.bsky.social · 04/04/2025
Celebrating the work of @lcferme.bsky.social ! As always with style! Congrats to the paper acceptance. More news will follow soon! Great weekend to all!
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NordenLab @nordenlab.bsky.social · 26/03/2025
Two very nice talks bringing our projects and their meaning across in 3min and lay terms…no slides…great job Margarida Cruz and @catfigueiredo.bsky.social ! #proudPI #GIMMretreat
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NordenLab @nordenlab.bsky.social · 02/03/2025
I had almost given up hope but it finally happened: @paveltomancak joined us here...Follow him fast so that he does not leave again...Welcome Pavel!!!
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NordenLab @nordenlab.bsky.social · 25/02/2025
@lcferme.bsky.social did outstandingly at her defense and now can call herself Doctor Lucrezia! It was a pleasure and honor to be part of this journey. Congrats! Great things will await you!
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NordenLab @nordenlab.bsky.social · 27/01/2025
Beautiful #ProudPI moment when former student Elisa Nerli introduces finishing PhD student @lcferme.bsky.social. Both Italian, both nailed their talks at the Physical Biology Circle meeting...
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NordenLab @nordenlab.bsky.social · 14/12/2024
Twice means it’s a tradition! Glühwein before Christmas organized by great @moritztreeck.bsky.social and with participation of @nordenlab.bsky.social. We Germans need to get the Portuguese into the spirit. It was even almost cold enough 😉
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NordenLab @nordenlab.bsky.social · 27/11/2024
I just leave this here…with the only thing noting is that I am happy and blessed to have worked, do work and will work with this incredible group of individuals and independent thinkers! Also… I love tiaras! Thank you!
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NordenLab @nordenlab.bsky.social · 15/11/2024
And it is finally there! The heroic effort by @lcferme.bsky.social paid off. Not always easy but resilience and stamina got us there. Thanks also to our collaborators Carl Modes and @haesleinhuepf.bsky.social for support! Check it out and let us know what you think! www.biorxiv.org/content/10.1...
biorxiv.org
Timely neurogenesis enables increased nuclear packing order during neuronal lamination
The coordination of cell proliferation, migration, and differentiation is crucial for organogenesis in many tissues, including the CNS and other organs that arise from pseudostratified epithelia (PSE)...
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NordenLab @nordenlab.bsky.social · 14/11/2024
Huge honor to win the Pfizer Premio for basic research! Thanks to all the team and especially Mauricio Rocha whose project made it possible… he could not be there tonight but the strong NordenLab support made up for it… we handled it with dignity but not without confusion 😉
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NordenLab @nordenlab.bsky.social · 11/11/2024
And it is out! Check out the new story of the lab that shows how nuclear deformabiliy influences their movements…and when… www.cell.com/current-biol...
cell.com
Nuclear deformability facilitates apical nuclear migration in the developing zebrafish retina
Maia-Gil et al. probe how nuclear properties affect apical nuclear migration in zebrafish neuroepithelia. Overexpressing lamin A stiffens nuclei, impairing migration. Further, control nuclei in a lami...
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NordenLab @nordenlab.bsky.social · 11/11/2024
OK, I am back! Sorry about being. a bit lazy. But I will now always double post and try to get this place a bit more vibrant. It seems a lot has moved in the last months. Will contribute.
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NordenLab @nordenlab.bsky.social · 11/02/2024
Just learned it is 'International Day of Women and Girls in Science'. Still not sure what to think about this concept. But I use it as a shout-out to the amazing women I had the pleasure to work with and/or train. You know who you are! We rock! Wherever your path might take you!
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NordenLab @nordenlab.bsky.social · 01/02/2024
Joined dinner of current and past @NordenLab members . Great thing that Portugal is such an attractive place to visit 😉
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