Integrin adhesions allow dynamic cell-matrix interactions to regulate cell behaviour. Here, the authors reveal that tensin 1, a multidomain adaptor protein, forms condensates in cells that act as reve...

Vocal fold cancer tumours lose some of their malignant traits when mechanically stimulated by physiological stretch or vibrations, mimicking the opening and closing of vocal folds and phonation.

The interplay between diverse cell types and their extracellular matrix (ECM) is fundamental for multicellular life. The ECM is a complex meshwork of …

The study reveals that newly synthesized integrins can bypass the Golgi to be actively delivered to specific plasma membrane regions, where they enhance ce

Epithelial protein lost in neoplasm (EPLIN), an actin-binding protein, has been described as both a tumor promoter and tumor suppressor in different c…

Epithelial protein lost in neoplasm (EPLIN), an actin-binding protein, has been described as both a tumor promoter and tumor suppressor in different c…

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Turun yliopistossa ja Turun biotiedekeskuksessa toimiva tutkimusryhmä on kehittänyt tavan kuvata leviävien rintasyöpäsolujen soluviestintää.

Cancer cell movement during metastasis is a dynamic process regulated by several different signals.

Turun yliopistossa ja Turun biotiedekeskuksessa toimiva tutkimusryhmä on kehittänyt tavan kuvata leviävien rintasyöpäsolujen soluviestintää. Menetelmä on paljastunut, että muihin syöpätyyppeihin parha...

Cancer cell movement during metastasis is a dynamic process regulated by several different signals. However, the way cells receive, process and respond to these signals has been extremely hard to dete...

Conway et al. show that integrin β1 phosphorylation is regulated through balanced activities of tyrosine kinases, such as Src and Arg, and phosphatases, such as PTP-PEST and Shp2, facilitating invadop...

Ivaskan työryhmä tutkii syöpäsolujen liikkumista ja leviämistä.

Integrin adhesion complexes mediate cell-extracellular matrix (ECM) interactions and undergo dynamic remodelling to regulate cell adhesion and migration. Here, we demonstrate that tensin 1 (TNS1), a m...

Integrin adhesion complexes mediate cell-extracellular matrix (ECM) interactions and undergo dynamic remodelling to regulate cell adhesion and migration. Here, we demonstrate that tensin 1 (TNS1), a m...

Vantaa, Finland – May 8th 2025 – Kohde Pharma Oy, a newly incorporated pharmaceutical company in Finland, is pleased to announce that it has secured its first investment from Finnish Drug Discovery Ce...

Kaikissa ihmisissä jotkut syövän esiasteet eivät kehity koskaan syöväksi, sanoo syöpätutkija Johanna Ivaska. Hän sanoo, että ihmiset voivat itse vaikuttaa syövän syntyyn korkeintaan kohtuullisesti.

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Apply for the Research Associate - Mechanisms Associated with Extracellular Matrix Assembly and Stability role on jobs.ac.uk, the top job board for academic positions in higher education. View details...

The 2025 Gordon Research Conference on Fibronectin, Integrins and Related Molecules will be held in Lucca (Barga), Lucca Italy. Apply today to reserve your spot.

The 2025 Gordon Research Seminar on Fibronectin, Integrins and Related Molecules (GRS) will be held in Lucca (Barga), Lucca Italy. Apply today to reserve your spot.

Can restoring vocal fold mechanics combat cancer? This preprint explores how!