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Johanna Ivaska

@johannaivaska.bsky.social
813 followers 852 following 18 posts

Cell biologist interested in cancer, in love with the archipelago and good books

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Johanna Ivaska @johannaivaska.bsky.social · 20/02/2026
What music should we play to our cells? This was the start of an amazing journey from @ivaskalab.bsky.social at @turkubioscience.bsky.social with Jasmin Kaivola and collaborators @sarawickstrom.bsky.social and others to explore larynx cancer mechanosensitivity! www.nature.com/articles/s41...
nature.com
Restoring the tumour mechanophenotype of vocal fold cancer reverts its malignant properties - Nature Materials
Vocal fold cancer tumours lose some of their malignant traits when mechanically stimulated by physiological stretch or vibrations, mimicking the opening and closing of vocal folds and phonation.
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Johanna Ivaska @johannaivaska.bsky.social · 05/02/2026
@mathildemathieu.bsky.social @ivaskalab.bsky.social New discovery from us! Leupaxin, a paxillin family member typically expressed in immune cells, negatively regulates durotaxis and mechanoresponsiveness in metastatic breast cancer cell variants and in cells cultured on soft ECM lnkd.in/diEk8DSR
lnkd.in
LinkedIn
This link will take you to a page that’s not on LinkedIn
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Mathilde Mathieu @mathildemathieu.bsky.social · 04/02/2026
I am very excited to share this preprint which has been my main postdoc project! We identified leupaxin as a negative regulator of durotaxis via paxillin-FAK inhibition in MDA-MB-231 brain and bone tropic metastatic variants. www.biorxiv.org/content/10.6...
biorxiv.org
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Guillaume Jacquemet @guijacquemet.bsky.social · 21/12/2025
I will be recruiting two postdocs early next year. - One image analyst - one biologist interested in working on lymphatics! Reach out if you are interested 👍
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Turku Bioscience @turkubioscience.bsky.social · 01/01/2026
There is a permanent positon open at our centre. Read more & apply 👉 ats.talentadore.com/apply/erikoi...
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Guillaume Jacquemet @guijacquemet.bsky.social · 15/01/2026
🚨 Job Alert! 🚨 We have an opening at our Microscopy Core Facility in Turku 🇫🇮. If you love imaging 🔬 and helping scientists succeed, we want you! 👇 abo.rekrytointi.com/paikat/index... #Microscopy #ScienceJobs #CoreFacility #Imaging @turkubioscience.bsky.social
abo.rekrytointi.com
Laboratory Engineer (Senior), in Advanced Imaging, 1.5.2026-31.12.2028
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Ivaska Lab @ivaskalab.bsky.social · 20/01/2026
Postdocs wanted - Please spread the word! We are looking for one bioinformatician and 1-2 cell biologists with different expertise! See the job ad below for more information and links to the job descriptions!
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Ivaska Lab @ivaskalab.bsky.social · 19/11/2024
Introductory post on 🦋! We're a research group headed by Prof. Johanna Ivaska interested in understanding how integrins contribute to every step of cancer progression. We're located at the Turku Bioscience Center in Turku, Finland! Find out more about us and our interests here: ivaskalab.utu.fi
ivaskalab.utu.fi
Ivaska cell adhesion and cancer Lab
Integrins, matrix, motility and mechanotransduction in cancer
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Michal Dibus @midibu.bsky.social · 07/01/2026
Proud to be part of this cool story by @follainga.bsky.social, led by @guijacquemet.bsky.social and @johannaivaska.bsky.social. Go and have a look!
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The EMBO Journal @embojournal.org · 08/01/2026
FlowVision: @guijacquemet.bsky.social @johannaivaska.bsky.social et al describe a fast label-free live imaging approach revealing key principles of cancer cell arrest on endothelial monolayers–such as flow dynamics & CD44 interaction with matrix hyaluronic acid link.springer.com/article/10.1...
link.springer.com
Fast label-free live imaging with FlowVision reveals key principles of cancer cell arrest on endothelial monolayers - The EMBO Journal
The rapid, transient, and unpredictable nature of interactions between circulating cells and the endothelium challenges the investigation of these events under flow conditions. Here, we developed an i...
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Johanna Ivaska @johannaivaska.bsky.social · 30/10/2025
Honoured and excited to launch this new RCF funded 2026-2031 project MechanoSpace with @ivaskalab.bsky.social. we will be hiring postdocs early next year www.utu.fi/fi/ajankohta...
utu.fi
Johanna Ivaska ja Jani Erola ovat Turun yliopiston uudet akatemiaprofessorit
Suomen Akatemia on myöntänyt viisivuotisen akatemiaprofessorin rahoituksen InFlames-lippulaivan molekulaarisen solubiologian professori Johanna Ivaskalle ja Invest-lippulaivan sosiologian professor
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EMBO Reports @emboreports.org · 09/09/2025
The first September issue is live. www.embopress.org/toc/14693178... The cover features work by Cassie Clarke @cassiejclarke.bsky.social @cruk-si.bsky.social and co-workers showing that UPP1 supports #metastasis by altering #immune and ECM landscapes. -> www.embopress.org/doi/full/10....
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Johanna Ivaska @johannaivaska.bsky.social · 16/07/2025
Excited to share our most recent study on #integrintraffic #cancer #migration #focaladhesion by @ivaskalab.bsky.social @drpaulinamoreno.bsky.social Niklas Jäntti et al www.sciencedirect.com/science/arti...
sciencedirect.com
EPLINα controls integrin recycling from Rab21 endosomes to drive breast cancer cell migration
Epithelial protein lost in neoplasm (EPLIN), an actin-binding protein, has been described as both a tumor promoter and tumor suppressor in different c…
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InFLAMES Research Flagship @inflames-flagship.bsky.social · 03/06/2025
Syövän nykyisillä lääkkeillä ei voida estää syövän leviämistä. Tilanne saattaa muuttua, sillä tutkijamme ovat kehittäneet tavan kuvata syöpäsolun sisäistä signalointia, joka on edellytys solun liikkumiselle. #Illusia @johannaivaska.bsky.social @ivaskalab.bsky.social @turkubioscience.bsky.social
inflames.utu.fi
Uusi koetin tekee näkyväksi syöpäsolun viestinnän, tutkijat voivat käyttää tietoa rintasyövän leviämisen estossa - InFLAMES-lippulaiva
Turun yliopistossa ja Turun biotiedekeskuksessa toimiva tutkimusryhmä on kehittänyt tavan kuvata leviävien rintasyöpäsolujen soluviestintää. Menetelmä on paljastunut, että muihin syöpätyyppeihin parha...
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Tom Van Agtmael @tomvanagtmael.bsky.social · 30/05/2025
New paper in Nature Cell Biol from @johannaivaska.bsky.social and @ivaskalab.bsky.social Dynamic regulation of integrin β1 phosphorylation supports invasion of breast cancer cells rdcu.be/eoAUD
rdcu.be
Dynamic regulation of integrin β1 phosphorylation supports invasion of breast cancer cells
Nature Cell Biology - Conway et al. show that integrin β1 phosphorylation is regulated through balanced activities of tyrosine kinases, such as Src and Arg, and phosphatases, such as PTP-PEST...
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Turun yliopisto - University of Turku @utu.fi · 02/06/2025
Miten syöpäsolut leviävät ja voidaanko sitä estää? Toistaiseksi ei, mutta tämä saattaa muuttua. Turun biotiedekeskuksen tutkijat löysivät keinon avata syöpäsolujen viestintää, ja tämän tiedon kautta saattaa löytyä lääke syöpäsolujen pysäyttämiseen. @ivaskalab.bsky.social @johannaivaska.bsky.social
utu.fi
Uusi koetin tekee näkyväksi syöpäsolun viestinnän, tutkijat voivat käyttää tietoa rintasyövän leviämisen estossa
Turun yliopistossa ja Turun biotiedekeskuksessa toimiva tutkimusryhmä on kehittänyt tavan kuvata leviävien rintasyöpäsolujen soluviestintää.
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James Conway @jrwconway.bsky.social · 12/02/2025
Ready to share our work as a poster at the upcoming Lorne Cancer Conference! Looking forward to discussing the role of integrin β1 in cancer invasion, and connecting with experts in the field. #LorneCancer2025
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James Conway @jrwconway.bsky.social · 26/05/2025
New paper from @ivaskalab.bsky.social out now! 🍾 Watch how cancer cell adhesion dynamics are disrupted by inhibiting the phosphatase Shp2 - key to integrin β1 phosphorylation. Blocking Shp2 impairs adhesion and reduces invasion potential. 🎥👇 Read more at: www.nature.com/articles/s41...
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Ivaska Lab @ivaskalab.bsky.social · 26/05/2025
Our newest paper is out in NCB. @jrwconway.bsky.social‬ designed a new FRET reporter, Illusia, to show the importance of integrin β1 phosphorylation dynamics in 3D invasion! Video: TNBC cells expressing Illusia with a Src (Saracatinib) or SHP2 (SHP099) inhibitor. www.nature.com/articles/s41...
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Johanna Ivaska @johannaivaska.bsky.social · 26/05/2025
Latest from @ivaskalab.bsky.social @jrwconway.bsky.social in NCB. We find that SHP-2 inhibition stops TNBC invasion and limits metastasis by blocking integrin dephosphorylation! Read more at: www.nature.com/articles/s41...
nature.com
Dynamic regulation of integrin β1 phosphorylation supports invasion of breast cancer cells - Nature Cell Biology
Conway et al. show that integrin β1 phosphorylation is regulated through balanced activities of tyrosine kinases, such as Src and Arg, and phosphatases, such as PTP-PEST and Shp2, facilitating invadop...
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Johanna Ivaska @johannaivaska.bsky.social · 20/05/2025
www.is.fi/kotimaa/art-... Great recognition to @ivaskalab.bsky.social research at @turkubioscience.bsky.social the Finnish Science Prize thanks to all my international friends and colleagues over the years
is.fi
Syöpätutkija Johanna Ivaskalle 100 000 euron tiedepalkinto
Ivaskan työryhmä tutkii syöpäsolujen liikkumista ja leviämistä.
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InFLAMES Research Flagship @inflames-flagship.bsky.social · 20/05/2025
Warm congratulations to our PI, Professor Johanna Ivaska👏💐🍾🎉🔥🔥🔥! @johannaivaska.bsky.social @ivaskalab.bsky.social
utu.fi
Finnish Science Award to Professor Johanna Ivaska
The Finnish Science Award 2025 has been awarded to Johanna Ivaska, Professor of Molecular Cell Biology at the University of Turku.
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Johanna Ivaska @johannaivaska.bsky.social · 20/05/2025
yle.fi/a/74-20162747
yle.fi
Syöpätutkija Johanna Ivaska palkittiin 100 000 eurolla – ”Levinnyt syöpä on edelleen suuri haaste”
Palkittu syöpätutkija kritisoi hallituksen säästöjä, jotka kohdistuvat yliopistojen perus­tutkimukseen.
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Riitta Monto @riittamonto.bsky.social · 20/05/2025
Paljon onnea Suomen tiedepalkinnosta, @johannaivaska.bsky.social Professorin viesti päättäjille: "Minä toivoisin, että Suomen valtiovalta ja poliitikot ymmärtäisivät, että pienessä maassa perustutkimus on se ainoa tapa, millä niitä paljon puhuttuja innovaatioita saadaan." www.ts.fi/uutiset/6665...
ts.fi
Suomen tiedepalkinto turkulaiselle syöpätutkijalle
Professori Johanna Ivaska pitää syöpää erityisen kiehtovana tutkimuskohteena ja innostuu siitä yhä uudelleen.
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Mari Riipinen @maririipinen.bsky.social · 20/05/2025
Tiedefoorumissa puhetta tieteestä. Onnittelut @johannaivaska.bsky.social Suomen tiedepalkinnosta.
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Helen Matthews @helenkmatthews.bsky.social · 01/05/2025
Happy to publish this News & Views article highlighting exciting new work from Rod Bremner's lab that shows that cell populations with a short cell cycle are intrinsically more susceptible to forming tumours
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eLife @elife.bsky.social · 23/03/2025
Using #CRISPR/Cas9 to genetically modify cells to produce extracellular matrices with altered compositions. elifesciences.org/reviewed-pre...
orange and cyan microscopy image of cartilage tissues
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Michal Dibus @midibu.bsky.social · 09/05/2025
Happy to share our Tensin 1 phase separation project is now on bioRxiv. www.biorxiv.org/content/10.1... This wouldn't be possible without @johannaivaska.bsky.social @ivaskalab.bsky.social #VattulainenLab #MSCA by @ec.europa.eu @turkubioscience.bsky.social @inflames-flagship.bsky.social
biorxiv.org
Adhesion-derived condensates control component availability to regulate adhesion dynamics
Integrin adhesion complexes mediate cell-extracellular matrix (ECM) interactions and undergo dynamic remodelling to regulate cell adhesion and migration. Here, we demonstrate that tensin 1 (TNS1), a m...
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Sam Aytekin @samaytekin.bsky.social · 02/05/2025
We did it! 🧪 After years of fiddling with gels, lasers, cells, and infinite lines of custom codes, our first preprint is out! We integrated TFM & FRET-based tension probes into one workflow to zoom in on focal adhesions mechanics 🔬 Already 400 downloads and I’m only mildly panicking 😅
biorxiv.org
Linking Molecular Tension and Cellular Tractions: A Multiscale Approach to Focal Adhesion Mechanics
Focal adhesions (FAs) are mechanosensitive structures that mediate force transmission between cells and the extracellular matrix. While Traction Force Microscopy (TFM) quantifies cellular tractions ex...
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Johanna Ivaska @johannaivaska.bsky.social · 16/05/2025
@midibu.bsky.social uncovers a FUNCTIONAL role for Tensin- 1 condensates acting as reservoirs of inactive focal adhesion proteins under the control of p38, ERK and AKT kinase activity. Protein-release from TNS1 condensates facilitate adhesion dynamics, filopodia, cell migration and cell invasion
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Johanna Ivaska @johannaivaska.bsky.social · 08/05/2025
Thanks for an amazing meeting GRC Fibronectin, integrins and related molecules @sarawickstrom.bsky.social and Guy
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Johanna Ivaska @johannaivaska.bsky.social · 08/05/2025
Well done GRS chairs Martina and @mchastney.bsky.social
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Pablo J. Sáez @pjsaez.bsky.social · 06/12/2024
As promised, here a fast acquisition of a migrating cell videoed under a microscopy, look those membrane dynamics @ the leading edge ! Bonus: nuclear deformation once the cell rear snaps. (Fluo nucleus, for the #fluorescencefriday) @focalplane.bsky.social @cellcommlab.bsky.social #CellMigration 🧪🔬
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Pablo J. Sáez @pjsaez.bsky.social · 13/01/2025
#CellMigration meets #SciArt Naomi Wee (naomiwee.com) did this great movie to explain how amoeboid migration works (also mesenchymal & cancer migration) Wanna know what happens if this leukocyte chooses the wrong path? Watch this ! www.youtube.com/watch?v=mPwn... @focalplane.bsky.social #SciSky
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James Briscoe @jamesbriscoe.bsky.social · 04/12/2024
Applications open for a new cohort of @dev-journal.bsky.social *Pathway to Independence* fellows Know a #devbio post-doc about to enter the academic job market? Would they benefit from a little support & mentoring? Spread the word Deadline 31 Jan 2025 journals.biologists.com/dev/pages/pi...
journals.biologists.com
PI programme | Development | The Company of Biologists
PI programme | Development | The Company of Biologists Development's Pathway to Independence programme Development is excited to announce our call for our Pathway to Independence program...
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bioRxiv Cell Biology @biorxiv-cellbio.bsky.social · 04/12/2024
Histology-Guided Single-Cell Mass Spectrometry Imaging using Integrated Bright-field and Fluorescence Microscopy www.biorxiv.org/content/10.1101/202…
biorxiv.org
Histology-Guided Single-Cell Mass Spectrometry Imaging using Integrated Bright-field and Fluorescence Microscopy https://www.biorxiv.org/content/10.1101/2024.12.03.626022v1
The rapidly evolving field of spatial biology revolves around the analysis of cells in their native
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Guillaume Jacquemet @guijacquemet.bsky.social · 04/12/2024
Fantastic work done by @follainga.bsky.social @sujanghimire.bsky.social @jwpylvanainen.bsky.social, Monika Vaitkevičiūtė, Diana Wurzinger, Camilo Guzmán, James Conway, Michal Dibus, Sanna Oikari Great collaboration with @johannaivaska.bsky.social @ivaskalab.bsky.social, Kirsi Rilla and Marko Salmi
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Xavier Trepat @xaviertrepat.bsky.social · 03/12/2024
🎈New preprint! We study how single cells move up, down and about fibronectin gradients. Experiments by @icfortunato.bsky.social, theory by David Bruckner. Collaboration with @raimonsunyer.bsky.social and @ehannezo.bsky.social 👇https://biorxiv.org/cgi/content/short/2024.12.02.626413v1
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Johanna Ivaska @johannaivaska.bsky.social · 04/12/2024
Excited to get to know the European Mechanobiology scientist better and meet old friends here in London
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Julia Eckert @juliaeckert.bsky.social · 16/11/2024
My first @epimechfc.bsky.social thread posted on X👇 What do star fish, snowflakes, and even cells have in common? I would like to take you on a journey into the field of soft matter and give you a brief overview of experimental observations on symmetries in biological systems. #EpithelialMechanics
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Mathilde Mathieu @mathildemathieu.bsky.social · 19/11/2024
@ivaskalab.bsky.social is here now 🎉🦋
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Ivaska Lab @ivaskalab.bsky.social · 21/11/2024
Here is the most recent preprint from our most recent PhD graduate, Dr Nicolas Pasquier. Orientation of mucinous CRC apicobasal polarity is regulated by tumor-stroma interactions. This work was a collaboration with the Jaulin lab at the Gustave Roussy Institute. www.biorxiv.org/content/10.1...
biorxiv.org
Signaling downstream of tumor-stroma interaction regulates mucinous colorectal adenocarcinoma apicobasal polarity
Mucinous colorectal carcinoma (MUC CRC) dissemination into the tumor stroma and metastasis to multiple organs, including the peritoneum, is associated with poor prognosis. Disseminating MUC CRCs exhib...
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Ivaska Lab @ivaskalab.bsky.social · 22/11/2024
Ivaska Lab at the Turku Bioscience Pikkujoulu party 🥳 Can you recognize our costumes? 😉 @omkarjoshi.bsky.social @mathildemathieu.bsky.social @mchastney.bsky.social @gounismichalis.bsky.social @sanshiya04.bsky.social
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Ivaska Lab @ivaskalab.bsky.social · 29/11/2024
We are all excitedly awaiting Jasmin to defend her PhD. A big thanks to her opponent, @rachellennon.bsky.social for being here today!
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Ivaska Lab @ivaskalab.bsky.social · 29/11/2024
We have a new doctor from the lab! Well done Jasmin! You did a wonderful job and are now the 22nd PhD student to graduate from the lab. We are immensely proud of you and we really enjoyed the discussion between you and @rachellennon.bsky.social, to whom we are very grateful. Now, it's party time!
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Johanna Ivaska @johannaivaska.bsky.social · 02/12/2024
I have moved to 🦋 as well ! Looking forward to reconnecting with old and initiating new science contacts here
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