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Vishank Jain-Sharma

@vishankjs.bsky.social
73 followers 94 following 9 posts

Postdoctoral associate in the Principles of Tissue Morphogenesis Lab led by PI Akankshi Munjal, in the Department of Cell Biology in the Duke University School of Medicine. www.munjallab.com Interested in the physics of living systems!

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Reposted by Vishank Jain-Sharma
Alessandro De Simone @desimonelab.bsky.social · 17/09/2026
How is proliferation modulated in regeneration for tissues to reach their right size? We found that, in zebrafish scales, proliferation is shut down by a moving front of osteoblast maturation. The front's dynamics scale with tissue size, ensuring proper osteoblast amplification. tinyurl.com/5e45twx3
tinyurl.com
A moving front of osteoblast maturation scales regenerating zebrafish bone
Successful regeneration recovers lost tissues to their original form. Here, we investigate how proliferation of bone-forming osteoblasts is timely regulated to control tissue size during zebrafish sca...
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Current Biology @currentbiology.bsky.social · 17/09/2026
New #cat just dropped! 😻 A first in over 100 years, a genomic study in CB by Eduardo Eizirik and team reveals a new species of 'tiger cat'. 👉 www.cell.com/current-biol... Meet the Tilcayo (Leopardus tilcayo)! (photo: Fernando Faciole/National Geographic) #cats
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Daniel Kierzkowski @kierzkowskilab.bsky.social · 10/09/2026
🌱 Our new paper about growth-derived mechanical conflicts in gynoecium and fruit morphogenesis is now out @currentbiology.bsky.social 🎉Congrats to Binghan Wang and all authors. 📄https://www.cell.com/current-biology/fulltext/S0960-9822(26)01086-9 @irbv.bsky.social @umontreal-en.bsky.social
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Alexandra Weber @toedtoad.bsky.social · 31/08/2026
My first paper is officially out in @currentbiology.bsky.social ! We found that snake embryos coil due to a mismatch in growth rates between the gut and spine. This tight coil is one of the reasons why snakes are able to get so long. Read the paper here!
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Andreas Schoenit @andreasschoenit.bsky.social · 01/09/2026
Excited to share a new preprint! We address a longstanding question related to stratifying tissues: What are the physical mechanisms that drive epidermal cell delamination? Find out why this👇 traction force pattern emerges and how it is linked to upward cell motion: www.biorxiv.org/content/10.6...
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Akankshi Munjal @akankshi.bsky.social · 24/07/2026
Excited to share our latest! www.biorxiv.org/content/10.6... This was a highly collaborative endeavor– the best way to do science. We asked how a developing tissue achieves the right shape despite all the variability along the way. Short answer: Hydrostatic pressure. Read on for the long answer!
3D-rendered confocal image of the embryonic zebrafish inner ear (otic vesicle) showing fluorescently labeled cell membranes. Three translumenal epithelial pillars span the lumen, partitioning it into the three semicircular canals (purple arrow: anterior canal; yellow arrow: posterior canal; white arrow: lateral canal)3D rendering of the segmented otic vesicle lumen at 3 days post-fertilization, showing the three connected fluid-filled compartments corresponding to the anterior, posterior, and lateral semicircular canals. The segmentation shows the characteristic geometry of the canals and the spaces partitioned by the transluminal epithelial pillars.
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Ricard Alert Zenón @ricardalert.bsky.social · 12/06/2026
Our paper on a Hamiltonian description of non-reciprocal interactions is out @natphys.nature.com! With Yubo Shi, Roderich Moessner, and @marinbukov.bsky.social @mpipks.bsky.social @ub.edu @icreacommunity.bsky.social Check it out, and read more in the thread below! 👇 www.nature.com/articles/s41...
nature.com
Hamiltonian description of non-reciprocal interactions - Nature Physics
Many active and driven systems exhibit non-reciprocal interactions, making them hard to describe with standard methods. Now a constrained Hamiltonian embedding with auxiliary variables reproduces thes...
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Bianca Dumitrascu @bimidu.bsky.social · 12/06/2026
How are two embryos alike? As we collect spatio-temporal microscopy data, we want to quantify variability in the timing of key developmental events. Alignment of multiple recordings is a core engineering challenge here and we suggest a solution; read about it: www.biorxiv.org/content/10.6...
biorxiv.org
A quantitative coordinate system for developmental dynamics
Quantitative comparison of morphogenesis across individuals remains a fundamental challenge, as developing embryos vary in shape, orientation and developmental tempo. Moreover, real-time three-dimensi...
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Akankshi Munjal @akankshi.bsky.social · 05/06/2026
Hosting my PhD mentor, @thomaslecuit.bsky.social was a welcome reminder of how fortunate I am to do what I do. It was a privilege to host him at Duke and reflect on what good mentorship can build. Thank you for coming, sharing your inspiring science, and for your unwavering support.
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Thomas Lecuit @thomaslecuit.bsky.social · 05/06/2026
Visiting Duke Univ. yesterday. What a treat to be hosted by @akankshi.bsky.social Munjal (former PhD std) 🤩 and spending time with fantastic trainees & wonderful faculty, such as Stefano di Talia @ditalialab.bsky.social. Many thanks for the invitation 🙏🏼. A place full of talent & energy.
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Biomedical Picture of the Day BPoD @bpodaily.bsky.social · 08/06/2026
Ear Bending: Atlas of genes active in single cells of the developing inner ear 📷 @akankshi.bsky.social & @kkukreja.bsky.social et al @swinburnelab.bsky.social @harvardmed.bsky.social in @elife.bsky.social ➡️ bpod.org.uk/archive/2026...
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Heemskerk Lab @heemskerklab.bsky.social · 18/05/2026
New preprint! We show that cell fate can be predicted from a snapshot of combinatorial signaling — and the underlying map is a single angle in signaling space. Work by first authors Bassit Fijabi and Seth Teague and collaboration with @davidbrueckner.bsky.social. www.biorxiv.org/content/10.6...
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Nicoletta Petridou @nicolettapetridou.bsky.social · 15/05/2026
Glad to see this out in its final form! www.nature.com/articles/s41... What changed since the preprint? Wonderful experiments disentangling the effect of receptor binding vs tissue porosity on Nodal diffusion, plus one of the smoothest review experiences! Thanks @natcellbio.nature.com & reviewers 🙏
nature.com
Tissue rigidity phase transition shapes morphogen gradients - Nature Cell Biology
Autorino et al. report a feedback loop between Nodal signalling and tissue phase transitions in zebrafish embryos. Nodal alters adhesion, triggering tissue rigidification and reduced porosity, which l...
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Fabrizio Musacchio @fabmusacchio.bsky.social · 10/05/2026
To my surprise, I recently learned that Hermann von #Helmholtz’s 1842 dissertation was not about #physics, but about the #NervousSystem. It was an anatomical study of invertebrate nervous systems, written at a time when the conceptual distinction between #neurons and #glia did not yet exist. 🧵1/...
My personal hard copy of De fabrica systematis nervosi evertebratorum. Die kommentierte Dissertation von Hermann Helmholtz. The book contains the original Latin text, a German translation, an English translation, and extensive commentary by Julia Heideklang, Hans-Joachim Pflüger, and Helmut Kettenmann. The fact that Helmholtz’s dissertation dealt with the nervous system was quite surprising to me, since I had always associated him with physics and mathematics.
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Zebrafish Rock! @zebrafishrock.bsky.social · 10/05/2026
High-speed video of a zebrafish larva feeding on a tasty paramecium. Credit to @georgelauder.bsky.social. #ZebrafishZunday 🧪
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Denis Wirtz @deniswirtz.bsky.social · 09/05/2026
Download our updated database of postdoc fellowships from different foundations and agencies. We identified 275 fellowships. For each entry, we provide description of the fellowship, focus, amount, deadline, eligibility, etc. Download this database here: research.jhu.edu/rdt/funding-...
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Tori Herridge @toriherridge.bsky.social · 07/05/2026
Happy centenary Sir David! Are there one hundred things named after David Attenborough? Surely we should be able to compile a list… I will start: 1. Attenborosaurus a plesiosaur from the Jurassic Coast en.wikipedia.org/wiki/Attenbo... Let’s see if we can get to 100! /🧵
en.wikipedia.org
Attenborosaurus - Wikipedia
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Yanlan Mao @yanlanmao.bsky.social · 06/05/2026
This exciting paper is now out in PNAS: www.pnas.org/doi/10.1073/...
pnas.org
3D epithelial cell topology tunes signaling range to promote precise patterning | PNAS
Cell behaviors in multicellular organisms are coordinated via both diffusible molecules and by signals based on direct cell–cell contacts. The mode...
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John Tuthill @tuthill.bsky.social · 04/05/2026
New preprint: Whole-body 3D kinematics of freely behaving 𝐷𝑟𝑜𝑠𝑜𝑝ℎ𝑖𝑙𝑎 New tech from @blobology.bsky.social & others at @hhmijanelia.bsky.social, which @ispizua.bsky.social and @elliottabe.bsky.social used to gain insight into 3D structure of locomotion & courtship www.biorxiv.org/content/10.6...
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Manlio De Domenico @manlius.bsky.social · 03/05/2026
The next time you find someone pretending to explain quantum mechanics, quantum computers and quantum artificial intelligence like a guru, keep in mind this short introduction to the field given by Prof. Shankar at Yale University. After it, you can start spreading ignorance too. Simply brilliant.
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Zebrafish Rock! @zebrafishrock.bsky.social · 24/04/2026
New work from Prober Lab @caltech.edu 🐟 💤 🔗 to original research: www.sciencedirect.com/science/arti...
sciencedirect.com
Melatonin promotes sleep by suppressing responses to visual stimuli via MT1 receptors
Sleep is regulated by a homeostatic process that increases sleep propensity with time spent awake and a circadian process that determines when most sl…
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epithelial mechanics fan club @epimechfc.bsky.social · 12/04/2026
How does an orbiting spherical tissue suddenly break symmetry and sprout invasive strands? We can predict this behavior from the initial morphology! Hi, I’m @jiwon-kim.bsky.social from @ianywonglab.bsky.social.
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Alushin Lab @alushinlab.bsky.social · 22/04/2026
Very pleased that after a rigorous (and lengthy) review process, our paper visualizing how myosin generated forces modulate actin filament structure for mechanosensitive recogntion by α-catenin has appeared in @nature.com : www.nature.com/articles/s41...
nature.com
Myosin forces remodel F-actin for mechanosensitive protein recognition - Nature
Structural studies demonstrate that myosin generates forces that cause structural changes in actin, modulating cooperative binding by α-catenin and thus signal transduction and intercellular communica...
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Mattia Serra @mattiaserra.bsky.social · 21/04/2026
📢Preprint: Positional information (PI) and information flows in dynamic tissues. Our mathematical framework quantifies, from data, how the coupled stochastic dynamics of cell positions and properties preserve, degrade and generate PI. @alex-plum.bsky.social www.biorxiv.org/content/10.6...
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UC Santa Barbara @ucsantabarbara.bsky.social · 19/04/2026
Congratulations to UC Santa Barbara's David Gross, who just won the 2026 Special Breakthrough Prize in Fundamental Physics, for a lifetime of groundbreaking contributions to theoretical physics—from the strong force to string theory. Full story: ow.ly/ZzyO50YMjzv
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Xavier Trepat @xaviertrepat.bsky.social · 17/04/2026
Our latest work on shape-programmable tissues is out in @science.org. By positioning topological defects in cellular nematics, we encode frustrated 2D force fields that relax into predictable 3D shapes. Collaboration with Marino Arroyo’s lab, led by @pauguillamat.bsky.social at @ibecbarcelona.eu.
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Lendert Gelens @lendertgelens.bsky.social · 17/04/2026
Temperature affects all biological rates, but how do we model its effects? Our 2-part review brings together modeling approaches from empirical curve fits to microscopic kinetics to network-level dynamics 🧵 Part I: doi.org/10.1016/j.coisb.2026.100577 Part II: doi.org/10.1016/j.coisb.2026.100578
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Denis Wirtz @deniswirtz.bsky.social · 15/04/2026
For scaling-laws aficionados (I am one), here are the graphs showing power-law behavior for vasculature for embryos (macaque, mouse, turtle). This means that the vasculature of developing embryos is scale free fractal. More here: www.biorxiv.org/content/10.6...
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EMBL @embl.org · 15/04/2026
Congratulations to Vikas Trivedi & collaborators for being awarded the HFSP grant! An international team coordinated by EMBL Barcelona researchers has been awarded $1.5M to study how developing organisms stay on track despite climate-driven temperature instability. www.embl.org/news/awards-...
embl.org
New funding to explore how embryos survive temperature stress in the era of climate change | EMBL
An international team coordinated by Vikas Trivedi at EMBL Barcelona has been awarded an HFSP grant worth $1.5 million (€1.3 M) to study how developing organisms stay on track despite climate-driven t...
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Peter Coles 🏳️‍🌈 🏳️‍⚧️ 🇮🇪 @telescoper.bsky.social · 09/04/2026
An independent arXiv I'm a bit late passing this news on, but a few weeks ago arXiv announced that from 1st July 2026 it will be establishing itself as an "independent nonprofit organization". It has been hosted for many years by Cornell University. You can read here about the reasons for this and…
telescoper.blog
An independent arXiv
I'm a bit late passing this news on, but a few weeks ago arXiv announced that from 1st July 2026 it will be establishing itself as an "independent nonprofit organization". It has been hosted for many years by Cornell University. You can read here about the reasons for this and how it will work, and there is a lengthier article in…
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Pierre Haas @lepuslapis.bsky.social · 04/04/2026
Now #published @physreve.bsky.social: "Elasticity and plasticity of epithelial gap closure" doi.org/10.1103/qtcv-gk3y #PhD work of Maryam Setoudeh, a model of cell intercalations during epiboly as elastoplastic deformations of a surface. @mpipks.bsky.social @mpi-cbg.de @csbdresden.bsky.social
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David Brückner @davidbrueckner.bsky.social · 14/03/2026
How do pairs of DNA loci - such as enhancers and promoters - find each other inside the nucleus? 🤔 Most models assume the random forces driving locus motion are independent in space New preprint by @janniharju.bsky.social: this assumption fails in living cells 🧵 www.biorxiv.org/content/10.6...
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Fredrik Jutfelt 🐠 @jutfelt.bsky.social · 20/03/2026
Here are some cute little wild zebrafish that we found in Nepal! 🧪🐟
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Igor Adameyko @adameykolab.bsky.social · 01/03/2026
Glob-glob! Absolutely magical sea anemone larva (about 7 mm) from The Lombok Strait, Indonesia 🇮🇩
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Zebrafish Rock! @zebrafishrock.bsky.social · 08/03/2026
First 24 hours of embryonic development in 9 different animal species: (From left to right) Zebrafish, Sea urchin, Black widow spider, Tardigrade, Sea squirt, Comb jelly, Parchment tube worm, Roundworm, Slipper snail. Credit to @tessamontague.bsky.social & Zuzka Vavrušová. #ZebrafishZunday #devbio 🧪
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Gladfelter Lab @gladfelterlab.bsky.social · 08/03/2026
Condensates are powerful ways to break symmetry and cells do remarkable things with them. Here we show that in a multinucleate fungus, a condensate regulates translation of a cyclin and a formin in distinct locations. www.nature.com/articles/s41...
nature.com
RNA-specific local translation is patterned by condensates for multinucleate cell growth - Nature Cell Biology
Geisterfer, Jalihal et al. show spatially distinct effects of Whi3 condensates on target translation in Ashbya syncytia. In vitro, translation is enriched at condensate–solute interfaces but repressed...
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James Briscoe @jamesbriscoe.bsky.social · 09/03/2026
New Perspective form Rory Maizels & me: "Gene regulatory networks: from correlative models to causal explanations" Gene regulatory networks are supposed to give us mechanistic explanations of development, so why are we drowning in 'hairballs' of statistical correlations? rdcu.be/e7zx7
rdcu.be
Gene regulatory networks: from correlative models to causal explanations
Nature Reviews Genetics - In this Perspective, Maizels and Briscoe discuss the limitations of current models of gene regulatory networks and outline solutions to harness data abundance without...
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Thibaut Brunet @thibautbrunet.bsky.social · 28/02/2026
Final version @nature.com of our paper describing unconventional multicellular development in a choanoflagellate inhabiting an extreme environment. A ton of new data since the first @biorxivpreprint.bsky.social preprint (which we've kept updating). A brief 🧵 (carried over from the old place)
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Fredrik Jutfelt 🐠 @jutfelt.bsky.social · 20/02/2026
Wild-caught zebrafish in Nepal 🦓🐟
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Nicoletta Petridou @nicolettapetridou.bsky.social · 19/02/2026
We summarised the many roles of material phase transitions in development (and they are not just mechanical 🤔)
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Paarth Gulati @paarthgulati.bsky.social · 11/02/2026
New preprint! arxiv.org/abs/2602.08105 We use mutual information to find the shared dimensionality of shared latent space between two high-dimensional variables. Turning inference into optimization, we use it to figure out dofs in movies and critical scaling in Ising!
arxiv.org
Mutual information and task-relevant latent dimensionality
Estimating the dimensionality of the latent representation needed for prediction -- the task-relevant dimension -- is a difficult, largely unsolved problem with broad scientific applications. We cast ...
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Kavli Institute for Theoretical Physics @kitp-ucsb.bsky.social · 19/11/2025
Advanced grad students + postdocs: apply for the 2026 #kitpqbio summer course, "Physical Principles of Morphogenesis in Plants and Animals," at buff.ly/OXXMKEv. Apply by Feb. 1. Course directors Adrienne Roeder (Cornell) and Sebastian Streichan (UCSB)
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Zebrafish Rock! @zebrafishrock.bsky.social · 30/01/2026
Instructors include @akankshi.bsky.social, @nicolettapetridou.bsky.social, @dianapinheiro.bsky.social, @chloeroffay.bsky.social, & @streichan.bsky.social among others! 🐟
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Paul Francois @pfrancois.bsky.social · 29/01/2026
Seconded. If anything, it has never been a better time to be a biophysicist, a complex system physicists, etc…. And it is a bit sad that much of it now happens *outside* of physics departments (for good and bad reasons…)
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Brugues Lab @brugueslab.bsky.social · 28/01/2026
Really excited to share our new paper in @nature.com! We uncovered how a physical instability of the cytoplasm coupled with the cell cycle drives cytoplasmic partitioning in early embryos #zebrafish #drosophila. Read more in this🧵 www.nature.com/articles/s41... 🤩 @poldresden.bsky.social @mpi-cbg.de
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Cambridge Morphogenesis Seminar Series @cammorphoseries.bsky.social · 23/01/2026
Next Monday 26th Jan, we are very excited to hear two talks from Margot Smit @likeyoda1.bsky.social and Susan Wopat @suewop.bsky.social! Visit our website(ucammorphogenesisseries.com) for more details, and be sure to subscribe to our mailing list(lists.cam.ac.uk/sympa/info/u...). See you soon!!
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Susie Wopat @suewop.bsky.social · 18/01/2026
Looking forward to sharing my postdoctoral work in just a little over a week at the UCAM Morphogenesis Series! 🐟🔬🔦
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Cambridge Morphogenesis Seminar Series @cammorphoseries.bsky.social · 16/01/2026
The Cambridge Morphogenesis Seminar Series is back! 🎉 Check out the flyer for a great lineup of speakers for Lent Term 2026! Don't forget to subscribe to our mailing list to get all the information, including the Zoom link. We are excited to see you again soon 👋
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Adrienne Roeder Lab @roederlab.bsky.social · 13/01/2026
Feb 1 deadline approaching for our @kitp-ucsb.bsky.social QBio summer course on Physical Principles of Morphogenesis in Plants and Animals. @streichan.bsky.social @maurazimmermann.bsky.social @maizel-lab.org @yusuke-mori.bsky.social @akankshi.bsky.social @nicolettapetridou.bsky.social
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Nikhil Mishra @nikhil-mishra.bsky.social · 12/01/2026
How does a uniform zygote reliably break symmetry? How do initially identical cells diverge in cell-cycle timing and transcriptional state? In our new paper in Nature Physics, we show that embryo geometry itself is sufficient to pattern early development. www.nature.com/articles/s41...
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