New paper out @natcellbio.nature.com! In embryos, immune cell migration is guided by the surrounding tissue flow. In turn, tissue flow is captured by active wetting theory, generalized to include influx from the upper cell aggregate! Check the thread below! 👇
www.nature.com/articles/s41...
nature.com
Tissue flow acts as a guidance cue for immune cell polarization and directional migration - Nature Cell Biology
Le et al. show that in Xenopus embryos, local ectodermal tissue flows provide a directional cue that polarizes and guides embryonic myeloid cells migration via cell-on-cell interactions.