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Fabrizio Musacchio

@fabmusacchio.bsky.social
970 followers 437 following 280 posts

Physicist by training, working in computational neuroscience at the @dzne.science. Interested in how neural dynamics and learning shape brain function and behavior, using modeling and data analysis. 🌍fabriziomusacchio.com 🐘mastodon.social/@FabMusacchio

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Fabrizio Musacchio @fabmusacchio.bsky.social · 4h
Today, I’m at the Great Data, Great Science Workshop in #Bonn, discussing practical solutions for #ResearchDataManagement, #DataScience, #OpenScience, and reusable workflows across disciplines. Looking forward to many perspectives and conversations ✌️
Building entrance with signage and bushes.
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Karl Deisseroth @deisseroth.bsky.social · 17h
Thank you to everyone sharing in this moment! I’m so grateful to all my trainees & collaborators… dlab.stanford.edu/group-members (pic: Peter and I together in 2017) Reading for all those asking: for technical details: dlab.stanford.edu for everyone: deisseroth.org/projections
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Nobel Prize @nobelprize.org · 05/10/2026
BREAKING NEWS The 2026 Nobel Prize in Physiology or Medicine has been awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel “for their discoveries concerning light-gated ion channels and optogenetics.”
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Marcus Ghosh @marcusghosh.bsky.social · 05/10/2026
Today, I'm launching my research group 🟣Neural forms🟠 @imperialcollegeldn.bsky.social We study how structure shapes function in artificial and biological neural networks. www.neural-forms.org 🤖🧠🧪 🧵 1/3
A logo for the neural forms group - made up from small circuit motifs.
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Friedemann Zenke @fzenke.bsky.social · 05/10/2026
1/9 New paper led by Michael Hauri & Peter Buttaroni: “Learning Commute-Time-Preserving World Models for Planning.” We show how to shape a world model's latent space so its distances mean something for planning.🧵 📄 arxiv.org/abs/2610.01373 💻 github.com/fmi-basel/co... 🌐 ctwm-website.github.io
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Mass Lab @masslab.bsky.social · 04/10/2026
Micro- and nanoplastics enter our bodies through food and water. But what happens once they pass through the gut barrier? In our new study in Nature Metabolism, we show that #Kupffer #cells, the resident #macrophages of the liver, are the main reservoir for ingested plastic.
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Fabrizio Musacchio @fabmusacchio.bsky.social · 04/10/2026
That’s awesome! Thanks @roberto-defilippo.bsky.social for this! 🙏
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DurstewitzLab @durstewitzlab.bsky.social · 04/10/2026
In our #NeurIPS2026 paper “A Minimal Interpretable Architecture for Zero-Shot Reconstruction of Dynamical Systems” (preprint: arxiv.org/abs/2607.14937) we reduce a DS FM to ingredients minimally necessary to reproduce long-term stat. and geom. properties of DS, even outperforming many TS & DS FM.
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Gabriel Peyré @gabrielpeyre.bsky.social · 03/10/2026
Inverse optimization seeks to recover the parameters of an optimization problem from observed solutions. When the objective depends linearly on these parameters, the gap loss is convex, yielding a convex formulation. Inverse optimal transport is one example. www.gpeyre.com/blog/2026/10...
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Earl K. Miller @earlkmiller.bsky.social · 03/10/2026
Sharp-wave ripples are not isolated hippocampal events. They are embedded in nested, brain-wide rhythms and coincide with visual-cortical synchronization at about 5 Hz. doi.org/10.64898/202... #neuroscience
doi.org
Awake sharp-wave ripples coincide with rhythmic cortical synchronization
Analysis of the Allen Institute Visual Coding Neuropixels dataset revealed a ~5 Hz synchronization of visual cortical activity in awake, immobile mice. During bouts of this rhythm, synchronized cortical bursts coincided with changes in the occurrence of sharp-wave ripples (SWRs) and dentate spikes and in SWR properties. Cortical synchronization, SWRs, and dentate spikes were also coordinated with slower pupil-size fluctuation, revealing that awake SWRs are embedded within nested brainwide rhythms. ### Competing Interest Statement The authors have declared no competing interest. Swiss National Science Foundation, https://ror.org/00yjd3n13, PR00P3_208598, PR00P3_208598/2, TMPFP3_210606 Synapsis Foundation, 2022-CDA02 University Research Priority Program (URPP) Adaptive Brain Circuits in Development and Learning (AdaBD).
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Ishmail Abdus-Saboor @ishmailsaboor.bsky.social · 02/10/2026
Excited to share my lab’s latest preprint led by postdoc @yukihaba.bsky.social and grad student Ryan Schwark. We surprisingly find that spontaneous behavior in isolation predicts a naked mole-rat’s identity, its colony membership, and even rank within its colony. www.biorxiv.org/content/10.6...
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German Neuroscience Society e.V. - NWG @neurowissg.bsky.social · 02/10/2026
Countdown for the early birds of the Göttingen Meeting is on: the Registration is open! But don´t forget: Early Registration, Abstract Submission & Stipend Applications close on 14 October 2026 We’re looking forward to your research & an inspiring conference! www.nwg-goettingen.de/2027/default...
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Bernstein Network Computational Neuroscience @bernsteinneuro.bsky.social · 02/10/2026
Looking forward to more discussions? See you next year in Lausanne for the #BernsteinConference 2027! 👋 buff.ly/pjMShi0
buff.ly
Bernstein Conference 2027 – Bernstein Network Computational Neuroscience
BERNSTEIN CONFERENCE
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Christian Schnell @neuroschnell.bsky.social · 02/10/2026
New paper in @plosbiology.org Biology from Theodore D. Satterthwaite's lab about the maturation of intrinsic timescale across the human cortex during development: journals.plos.org/plosbiology/...
journals.plos.org
Intrinsic timescale develops hierarchically from sensorimotor to association cortex in youth and stabilizes in adulthood
Intrinsic timescale reflects the temporal window of neural processing, but how it matures across the human cortex during development remains unclear. This study shows that intrinsic timescale develops...
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Universität zu Köln @unicologne.bsky.social · 02/10/2026
🎉 We are excellent The #UniCologne has succeeded with its proposal “Neue Universität: Continuous Change – Successful Renewal” and has been awarded the status of a ‘University of Excellence’ as part of the Excellence Strategy of the Federal and State Governments ➡️uni.koeln/SWUK7
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Anh Hoang Le, PhD 🏳️‍🌈🏴󠁧󠁢󠁳󠁣󠁴󠁿🇻🇳 @anhhle2702.bsky.social · 02/10/2026
Happy #FluorescenceFriday. Single immune cell migration is fascinating. But these cells can also behave like a coordinated collective, like 🐝 from a hive. I captured some embryonic myeloid cells (🔴) displaying swarming behaviour in a migrating ectoderm cell sheet (🔵), like neutrophils in our body!
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Matthijs Pals @matthijspals.bsky.social · 02/10/2026
Finally, we predict memory subspaces can be perturbed independently, selectively changing behavioral responses. See our paper: www.biorxiv.org/content/10.6... Code: github.com/mackelab/swm... @unituebingen.bsky.social @ml4science.bsky.social @tuebingen-ai.bsky.social @mackelab.bsky.social [4/4]
biorxiv.org
Attractor dynamics underlie sequence working memory in data-constrained recurrent neural networks
Sequences of stimuli can be maintained in working memory by encoding each item, together with its position, as a distinct pattern of neural population activity. Competing hypotheses about the underlyi...
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Matthijs Pals @matthijspals.bsky.social · 02/10/2026
What kind of dynamics underlie sequence working memory? In the last project of my PhD we developed and analysed RNNs fitted to multi-session single-unit data of macaques. Now out on: www.biorxiv.org/content/10.6... With @jakhmack.bsky.social and data from Chen et al., Neuron 2024. [1/4]
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Rui Ponte Costa @somnirons.bsky.social · 01/10/2026
Great summary of our paper with @mark-j-wagner.bsky.social
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Ivy Chan @ivychanchiwai.bsky.social · 25/09/2026
Our paper on odour categorization in the Drosophila mushroom body is now out in Cell Reports! 🎉 We found that αβ and α′β′ Kenyon cells—but not γ KCs—distinguish food-related from non-food odours at the population level. Very happy to see this work published! 🪰🧠 doi.org/10.1016/j.ce...
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DurstewitzLab @durstewitzlab.bsky.social · 01/10/2026
In our #NeurIPS2026 spotlight “Parallel-in-Time Training of Recurrent Neural Networks for Dynamical Systems (DS) Reconstruction” (preprint: arxiv.org/abs/2605.12683) we speed up training of nonlinear RNNs on time series from chaotic DS by >100x by combining DEER with generalized teacher forcing.
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David G. Clark @david-g-clark.bsky.social · 01/10/2026
📣 Multiple Flatiron Research Fellow (FRF) postdoc positions are available in my @flatironinstitute.org group! We've never been better positioned to understand how high-dimensional nonlinear dynamical systems (neural circuits!) compute. If this is as exciting to you as it is to me, consider applying:
apply.interfolio.com
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
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neurosock @neurosock.bsky.social · 28/11/2025
The hippocampus is not a library, it is a simulation engine. HPC is known for storing maps of the environment but not so known for generating planned trajectories. This paper proposes that recurrence in CA3 is crucial for planning. A🧵with my toy model and notes: #neuroskyence #compneuro #NeuroAI
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Hayoung Song @hayoungsong.bsky.social · 30/09/2026
Medial PFC interacts with the hippocampus to retrieve context-congruent memories.. but HOW?? was what started this. Simulating mPFC-HIP🧠, we designed an RNN🤖 that retrieves memories similar in context, on top of self-attention. It learns to retrieve like humans faster! arxiv.org/abs/2609.37791
arxiv.org
A neural network that maintains and retrieves memories based on context
Every day, people continuously infer situational context and adjust the way they understand and remember the world. Context, signaled by the prefrontal cortex, is known to modulate working memory and ...
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Earl K. Miller @earlkmiller.bsky.social · 30/09/2026
Conserved neural dynamics of anesthesia and the oblivion of species. www.nature.com/articles/s41... #neuroscience
nature.com
Conserved neural dynamics of anesthesia and the oblivion of species - Nature Neuroscience
General anesthetics seem to work in all living species. This raises the question of whether there are common changes in neural activity that occur during transitions between wakefulness and anesthesia...
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ESA Space Science @science.esa.int · 30/09/2026
Inspector Smile is ready for science! 🫡 This is Smile’s first ultraviolet view showing an auroral substorm. With the ultraviolet camera now operational, Smile becomes the first spacecraft since 2008 to capture the full ring of northern lights around the north pole in ultraviolet light. 🔭 🧪 ☀️
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Fabrizio Musacchio @fabmusacchio.bsky.social · 30/09/2026
@nest-initiative.org is at the #BernsteinConference too! They have a booth here, so pass by if you’re interested in large-scale spiking network simulations, #ComputationalNeuroscience, or simply want to learn more about #NESTSimulator 🙂 🌍 nest-simulator.org #CompNeuro #SNN #Python
A brochure with the text NEST:: and THE OPEN SOURCE ECOSYSTEM FOR BIOLOGICALLY REALISTIC NEURAL NETWORK SIMULATIONS AT CELLULAR RESOLUTION on a dark background.
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Dimitra Maoutsa @dimma.bsky.social · 30/09/2026
And since I obviously forgot to post about my own poster yesterday🧠 If you’re interested in 𝐦𝐞𝐭𝐚-𝐥𝐞𝐚𝐫𝐧𝐢𝐧𝐠 𝐭𝐡𝐫𝐞𝐞-𝐟𝐚𝐜𝐭𝐨𝐫 𝐩𝐥𝐚𝐬𝐭𝐢𝐜𝐢𝐭𝐲 𝐫𝐮𝐥𝐞𝐬 𝐭𝐡𝐚𝐭 𝐦𝐚𝐤𝐞 𝐑𝐍𝐍𝐬 𝐥𝐞𝐚𝐫𝐧 𝐜𝐨𝐦𝐦𝐨𝐧 𝐧𝐞𝐮𝐫𝐨𝐬𝐜𝐢𝐞𝐧𝐜𝐞 𝐭𝐚𝐬𝐤𝐬, come talk to me! I’ll be around until the end. @bernsteinneuro.bsky.social 🔗 abstracts.g-node.org/conference/B...
abstracts.g-node.org
Bernstein Conference 2026
Conference Abstracts
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Scott Juntti @scottjuntti.bsky.social · 27/09/2026
When a fish sees the world move, it immediately swims with it. This is the optomotor response: a visual reflex found across animals that helps us maintain our position and orientation as our surroundings appear to drift. 🐟👀
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Dimitra Maoutsa @dimma.bsky.social · 30/09/2026
If you are at #BernsteinConference @bernsteinneuro.bsky.social today, come by 𝐩𝐨𝐬𝐭𝐞𝐫 𝐈𝐈𝐈 𝟖𝟗 to listen from @johnmadridcarvajal.bsky.social 𝐡𝐨𝐰 𝐫𝐞𝐰𝐚𝐫𝐝 𝐬𝐡𝐚𝐩𝐞𝐬 𝐧𝐞𝐮𝐫𝐚𝐥 𝐩𝐨𝐩𝐮𝐥𝐚𝐭𝐢𝐨𝐧 𝐝𝐲𝐧𝐚𝐦𝐢𝐜𝐬 in 🐁 visual crtx. Work with 𝗞𝗮𝘁𝗷𝗮 𝗞𝗮𝘂𝗿𝗶𝗻𝗸𝗼𝘀𝗸𝗶, 𝗜𝘀𝗵𝘁 𝗦𝗶𝗻𝗴𝗵, 𝗥𝗼𝗵𝗶𝘁 𝗝𝗲𝘀𝘄𝗮𝗻𝘁𝗵🧠 🔗 abstracts.g-node.org/conference/B...
abstracts.g-node.org
Bernstein Conference 2026
Conference Abstracts
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Fabrizio Musacchio @fabmusacchio.bsky.social · 30/09/2026
Happy to see "Size-dependent #plastic exposure disrupts #macrophage function and tissue-specific #metabolism" now out in @nature.com Metabolism! Congrats to Nikola, @mariafviola.bsky.social, @masslab.bsky.social & everyone involved 🙏 Glad to have been involved in this work! #neuroscience 1/2
doi.org
Size-dependent plastic exposure disrupts macrophage function and tissue-specific metabolism - Nature Metabolism
This study reports that chronic exposure to microplastic and nanoplastic particles differentially affects Kupffer cells, which impairs their function and has consequences on both liver and systemic me...
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aaron bornstein @aaronbornstein.bsky.social · 29/09/2026
New lab preprint! @khoudary.bsky.social presents a tour-de-force: a new model of how uncertain expectations should help resolve uncertain sensations, supported by re-analysis of four experiments in monkeys (behavior, ephys) and humans (behavior, fMRI, EEG, intracranial) @meganakpeters.bsky.social
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The Transmitter @thetransmitter.bsky.social · 29/09/2026
Granule cells may allow the brain to simultaneously generalize across tasks—avoiding the need to learn each new challenge from scratch—while still capturing what makes each situation distinct. #neuroskyence By Holly Barker www.thetransmitter.org/cerebellum/c...
thetransmitter.org
Cerebellum discerns similar actions by reorienting activity
The findings provide a new perspective on how granule cells in the cerebellum help to generalize across tasks.
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Bernstein Network Computational Neuroscience @bernsteinneuro.bsky.social · 29/09/2026
Day two of #BernsteinConference 2026 is underway! 👋 The main conference has officially begun, and it’s great to see the plenary room filling up in Frankfurt. #BernsteinNetwork #Neuroskyence
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Tim Vogels @tpvogels.bsky.social · 29/09/2026
Here are the lab’s posters at #bernstein26. Please come visit and ask us all the pesky questions!
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Fabrizio Musacchio @fabmusacchio.bsky.social · 29/09/2026
The satellite workshops at the #BernsteinConference yesterday and today were already fantastic! I enjoyed every single talk and discussion. And today, the main conference kicked off as well. What a great start! #CompNeuro
Person walking toward building with banners. Setting includes bicycles and tables.Shot with No Fusion by "NC".
People attending a conference lecture titled "Shaping plasticity: Structural constraints and temporal dynamics in learning" at the Bernstein Conference 2026.Shot with No Fusion by "NC".
Crowd of people gathered in a spacious, modern conference center lobby, engaging in conversations and waiting near registration tables.Shot with No Fusion by "NC".
Audience attending the Bernstein Conference on Computational Neuroscience in a large, modern auditorium with digital screens and natural light.
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Oliver Barnstedt @obarnstedt.bsky.social · 29/09/2026
It was great fun talking science to Svilen. Thanks for having me!
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Ben Fulcher @bendfulcher.bsky.social · 29/09/2026
Today I'm releasing the "1000×1000 collection": a unified place to learn about dynamical structure. 1000 simulated time series (1000 samples each) spanning 133 dynamical processes. Have a play? 🐛 #timeseries #dynamicalsystems #complexity #opendata dynamicsandneuralsystems.github.io/1000x1000/
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Anthony Ramnauth @philoneurosci.bsky.social · 28/09/2026
Exponentiated gradient learning yields #brain -like #synaptic distributions: Neuron www.cell.com/neuron/fullt...
cell.com
Exponentiated gradient learning yields brain-like synaptic distributions
Cornford et al. show that exponentiated gradient (EG) learning, which updates synapses multiplicatively, matches gradient descent on cognitive tasks while respecting Dale’s law and producing brain-lik...
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Bernstein Network Computational Neuroscience @bernsteinneuro.bsky.social · 28/09/2026
☕️ A little coffee-break moment from day one of #BernsteinConference 2026! Our Satellite Workshops are underway in Frankfurt — with plenty of time for discussions, exchanges and catching up between sessions. #BernsteinNetwork #Neuroskyence
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Tim Vogels @tpvogels.bsky.social · 28/09/2026
Welcome to #Bernstein2026! At the bottom of the programme you can find this little gem, COMPLETE workshop schedules!! My mind is blown by little things, but Iwtyo when I saw a conference pull this off successfully! Thanks @bernsteinneuro.bsky.social & take notice @cosynemeeting.bsky.social
All in one Bernstein Conference for Computational Neuroscience workshop schedule for Monday: https://bernstein-network.de/bernstein-conference/program/satellite-workshops/#tab-id-1All in one Bernstein Conference for Computational Neuroscience workshop schedule for Tuesday: https://bernstein-network.de/bernstein-conference/program/satellite-workshops/#tab-id-2
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Matthijs Pals @matthijspals.bsky.social · 28/09/2026
What are the dynamics underlying sequence working memory? To found out, we develop and analyse RNNs fitted to multi-session single-unit data of macaques. See my talk Wed 12:00, at @bernsteinneuro.bsky.social. With @jakhmack.bsky.social @mackelab.bsky.social Data from Chen et al., Neuron 2024.
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Aitor Morales-Gregorio @aitormg.bsky.social · 28/09/2026
Don't miss our latest poster at #Bernstein2026 on Tuesday afternoon II-25 "Wiring without firing: geometric rules generate brain architecture and dynamics" Conference abstract 💬: doi.org/10.12751/nnc... Preprint 📝: doi.org/10.48550/arX...
doi.org
Bernstein Conference 2026
Conference Abstracts
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Fabrizio Musacchio @fabmusacchio.bsky.social · 28/09/2026
On my way to #Frankfurt for #BernsteinConference 🚅✌️ Tomorrow evening, I’ll present our poster on constrained inhibitory #plasticity in competitive #STDP networks and how inhibitory budget matching can stabilize plastic competition. (session II, #46) Come by if you’re around 😊
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Scott Juntti @scottjuntti.bsky.social · 27/09/2026
Pairing this assay with our cichlid GCaMP calcium imaging will let us watch neural activity while they perform the behavior—connecting sensory processing, motor control, and evolutionary change in a highly accessible vertebrate system. Looking forward to more #neuroethology in this model!
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Ana Dorrego Rivas @adorrego.bsky.social · 25/09/2026
Dendritic shaft constrictions shape synaptic integration in neurons www.science.org/doi/10.1126/...
science.org
Dendritic shaft constrictions shape synaptic integration in neurons
For nearly 150 years, textbooks have described dendritic morphology as optimized for efficient synaptic voltage transfer from spines to the soma, implemented as a tubular design respecting Rall’s 3/2 ...
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Adrian Duszkiewicz @adrian-du.bsky.social · 26/09/2026
Interesting new study from the Frank lab: Hippocampal representations of alternative possibilities are flexibly generated to meet cognitive demands
cell.com
Hippocampal representations of alternative possibilities are flexibly generated to meet cognitive demands
Comrie et al. show that the hippocampus flexibly represents different alternative possibilities—including paths ahead, behind, and far away—to meet distinct cognitive demands related to decision-makin...
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Mia Konjikusic, PhD @konjikusicmia.bsky.social · 25/09/2026
To add to all the lovely videos of non-AI processes multicilia beating: ctenophore multiciliated cells! They can reach up to 1mm long, causing a rainbow light refraction effect with the correct light positioning! Taken by myself at MBL in 2019 embryology. Realtime frame-rate!
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Torben Ott @torbenottlab.org · 02/09/2026
#Psilocybin🍄 shifts visual cortex dynamics towards a state of surprise! Thrilled to share our work w/ OpenScope at @alleninstitute.org lead by postdoc @roberto-defilippo.bsky.social. We combined visual change detection w/ Neuropixels recordings in mice to uncover how psilocybin changes circuits 1/
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Valentin Dunsing-Eichenauer @dunsingvalentin.bsky.social · 25/09/2026
#FluorescenceFriday: Given the recently grown interest in ciliary beating, here is a movie of beating cilia in a human airway model that I captured last week with lattice light-sheet microscopy. No AI „processing“, this is the raw data! Frame rate is ca. 170fps, displayed here at 25fps.
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