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Nicoletta Petridou

@nicolettapetridou.bsky.social
1.8K followers 536 following 44 posts

Biologist inspired by physics | Group Leader, Developmental Biology Unit, EMBL Heidelberg

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Reposted by Nicoletta Petridou
Hanh Vu @hanhtkvu.bsky.social · 01/07/2026
Super excited that the first preprint from the lab is out! Led by an amazing student, Gaurav @gvaidya.bsky.social, jointly supervised with @mwdorr.bsky.social.
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Nicoletta Petridou @nicolettapetridou.bsky.social · 23/06/2026
Double preprint! 👇 Check out our latest studies on timing, heterogeneity and collective behaviour (with a fun tiny bonus on evolution!) 1. www.biorxiv.org/content/10.6... 2. arxiv.org/abs/2605.13234
biorxiv.org
Cellular timing heterogeneity regulates phase transitions in living matter
Rigidity transitions govern tissue organization in ways reminiscent of inert materials. Yet, living tissues are composed of active units with autonomous timing mechanisms, raising the question whether...
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Mike Dorrity @mwdorr.bsky.social · 19/06/2026
First pre-print from the lab, a collaborative effort led by Jess Bourn @bournsupremacy.bsky.social, a fantastic PhD in my group. We resolve a key problem in development + evolution: how do we quantify heterochrony and link temporal variation to phenotype? www.biorxiv.org/content/10.6...
biorxiv.org
Quantitative mapping of heterochrony to species-specific phenotypes
The genetic program of animal development is conserved, but its rate of execution varies across species. Heterochrony, shifts in the relative timing of developmental events, generates phenotypic varia...
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Nicoletta Petridou @nicolettapetridou.bsky.social · 16/06/2026
A very pleasant surprise to see that we got the cover for this paper 🥳 @natphys.nature.com
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Nicoletta Petridou @nicolettapetridou.bsky.social · 02/06/2026
Here the published version of our work on uncoupling different types of tissue phase transitions during development! Find out more on how contact surface tension-driven rigidity transitions trigger tricellular junction formation and initiate epithelial organization! @natphys.nature.com
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EMBL @embl.org · 02/06/2026
How do the physical properties of embryos affect their development? New research from EMBL scientists and collaborators shows that tissue mechanics actively influence developmental signalling – revealing new links between physics and embryogenesis. www.embl.org/news/science...
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Nicoletta Petridou @nicolettapetridou.bsky.social · 15/05/2026
Glad to see this out in its final form! www.nature.com/articles/s41... What changed since the preprint? Wonderful experiments disentangling the effect of receptor binding vs tissue porosity on Nodal diffusion, plus one of the smoothest review experiences! Thanks @natcellbio.nature.com & reviewers 🙏
nature.com
Tissue rigidity phase transition shapes morphogen gradients - Nature Cell Biology
Autorino et al. report a feedback loop between Nodal signalling and tissue phase transitions in zebrafish embryos. Nodal alters adhesion, triggering tissue rigidification and reduced porosity, which l...
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Sinem Saka @sinemsaka.bsky.social · 20/03/2026
Spectral multiplexing is typically limited to 4-5 channels. Our new preprint introduces a framework that utilizes DNA barcoding and signal tuning to enable robust spectral unmixing and ground-truth benchmarking to achieve 15-plex subcellular profiling without cycling www.biorxiv.org/content/10.6...
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Aissam Ikmi @aikmi.bsky.social · 20/03/2026
Our study on shape diversity in cnidarians is now published. The final version includes extensive new data that substantially extend the original bioRxiv preprint. Congrats to everyone who contributed to this work! www.cell.com/cell/fulltex... @embl.org
cell.com
Deciphering mechanical determinants of morphological evolution
A comparative analysis of cnidarian larval morphogenesis combined with active surface theory identifies a set of mesoscale mechanical modules that predict species-specific shapes. Manipulating these m...
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Nicoletta Petridou @nicolettapetridou.bsky.social · 04/03/2026
We have extended the abstract deadline by a week! Looking forward to seeing you many of you here!
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Nicoletta Petridou @nicolettapetridou.bsky.social · 25/02/2026
Less than a week left for abstract submission for #EESMechanobiology - join us in this long-standing meeting on the mechanics of life.
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EMBL Events @events.embl.org · 24/02/2026
Welcome to 'Collectivity in living systems'! During the next few days we'll explore coordination, cooperation, emergence, and decision-making in systems ranging from bacterial biofilms and cell migration to tissue formation, disease models, and animal behaviour. Let's go! 🙌 #EESCollectivity
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German Fish Model Research Meeting @germanfishmeeting.bsky.social · 23/02/2026
🐠 Calling all fish model researchers! 🐠 The 1st German Fish Model Research Meeting is happening in Heidelberg, Sept 16–18, 2026—and you don’t want to miss it ! 👉https://www.germanfishmeeting.org/ #daniorerio #fishmodel #germanfish2026 #medaka #killifish #cavefish
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Pauli Group (posts by Andi Pauli) @pauligroup.bsky.social · 23/02/2026
Join us in Vienna for the biggest international 'FISH' meeting in 2026! No matter which fish is your favorite model - zebrafish, medaka, killifish, cavefish, Danionella, cichlids, stickleback, you name them...- this meeting is for you! www.ezm2026.org Abstract submission deadline is March 15th.
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EMBL @embl.org · 19/02/2026
Our cells are experts at navigating inherently noisy and complicated environments. EMBL researchers are using theoretical physics approaches to uncover fundamental principles behind how cells use complex information to self-organise. www.embl.org/news/science...
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Nicoletta Petridou @nicolettapetridou.bsky.social · 19/02/2026
We summarised the many roles of material phase transitions in development (and they are not just mechanical 🤔)
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EMBL DB unit @embldbunit.bsky.social · 22/01/2026
✨ At this week's DB seminar, Magdalena Schindler @lena-schindler.bsky.social, a postdoc in the Petridou group @nicolettapetridou.bsky.social @embl.org, presented her work on how cell cycle synchrony affects tissue-level mechanical transitions at the onset of morphogenesis in zebrafish embryos 🐟 🔬
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epithelial mechanics fan club @epimechfc.bsky.social · 18/01/2026
How can structures at the vertex of 3 cells have effects at the tissue level? Join me, @laura-rustarazo.bsky.social, to explore how tricellular junctions (TCJs) act as local tension sensors and regulators of global tissue organization. 🧵⤵️ doi.org/10.1126/scie...
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EMBL @embl.org · 27/11/2025
Anthony A. Hyman will become EMBL’s next Director General. He joins EMBL from @mpi-cbg.de in Dresden. He is also Professor of Molecular Biology @tudresden.bsky.social, and was a group leader at EMBL Heidelberg from 1993 to 1999. www.embl.org/news/people-...
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Prisca Liberali @priscaliberali.bsky.social · 26/11/2025
Emergence and Self-organisation across biological scales! I hope you are ready for next year conference! It will be an incredible event April 20-22 2026. The first of many #LakeConference organised by @ehannezo.bsky.social @alleninstitute.org and James Sharpe @embl.org
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Nicoletta Petridou @nicolettapetridou.bsky.social · 19/11/2025
One more week to apply for this exciting symposium on collective behaviour 👇👇👇
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EMBL Events @events.embl.org · 11/11/2025
You only have one more week to submit your abstract for 'Collectivity in living systems: emergence, function, and evolution' 👉 s.embl.org/ees26-01-bl Don't miss #EESCollectivity which will explore how collective behaviours arise from fundamental principles across biological systems🦠🐒🧬
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jordivangestel.bsky.social @jordivangestel.bsky.social · 08/11/2025
Please join us for this exciting new conference on the emergence, function and evolution of biological collectives - unpacking the wonderful world of self-organization: www.embl.org/about/info/c...
embl.org
Collectivity in living systems: emergence, function, and evolution
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Nicoletta Petridou @nicolettapetridou.bsky.social · 07/11/2025
Only a few days left for abstract submission at the brand new EMBO|EMBL Symposium Collectivity in living systems: emergence, function and evolution. We have stellar speakers in cell, animal collectives & beyond @priscaliberali.bsky.social @icouzin.bsky.social @ricardsole.bsky.social Join us!
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James Briscoe @jamesbriscoe.bsky.social · 07/10/2025
Very sad news, John Gurdon has died. A developmental biologist's developmental biologist, Nobel prize winner His work is the foundation of much of today's dev & stem cell bio. An inspiration to many, including me. Always asking questions & wanting the answers www.magd.cam.ac.uk/news/profess...
magd.cam.ac.uk
Professor Sir John Gurdon FRS (1933-2025) | Magdalene College
Magdalene College is deeply saddened to announce the death of Professor Sir John Gurdon FRS, who served as Master of the College from 1995 to 2002.
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Sara Wickstrom @sarawickstrom.bsky.social · 12/09/2025
My lab @mpi-muenster.bsky.social is looking for a computational biologist with a passion for imaging and spatial biology. A staff scientist position with long-term perspective! Apply and spread the word 🙏 jobs.mpi-muenster.mpg.de/jobposting/0...
jobs.mpi-muenster.mpg.de
Computational image analyst (m/f/d)
The Max Planck Institute for Molecular Biomedicine in Münster, Germany, has an opening for a
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Jan Rombouts @janrombouts.bsky.social · 18/09/2025
Please allow me to introduce... our new preprint 🎉 Together with Michael Zhao, Anna Erzberger and Alexander Aulehla, we investigate pattern formation due to aggregation in confined systems. You can find it at arxiv.org/abs/2509.08533 @michaelzhao.bsky.social @erzbergerlab.bsky.social
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EMBL @embl.org · 04/09/2025
Congratulations, Michael Dorrity and Anna Erzberger! The two EMBL Heidelberg group leaders have received ERC Starting Grants that will enable ambitious projects related to developmental timing and tissue self-organisation, respectively. Learn more: www.embl.org/news/awards-...
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Ricard Solé @ricardsole.bsky.social · 01/09/2025
How did differentiation evolve to allow for complex multicellular systems? In this @cp-trendsecolevo.bsky.social‬ paper, Boolean networks are used to answer long-standing questions in the evolution of cell type diversity. @wcratcliff.bsky.social d1wqtxts1xzle7.cloudfront.net/115269531/j....
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Jan Rombouts @janrombouts.bsky.social · 29/08/2025
Many years in the making but now finally online! What determines the temperature scaling and thermal limits of cell cycle duration in embryos? We tackled the question using a combination of dynamical systems analysis and experimental measurements in embryos and in cycling Xenopus extracts.
A plot showing the duration of the early embryonic cell cycle of 5 different species as a function of temperature. Higher temperatures mean faster cycles, up to an optimum, beyond which the cycles slow down and eventually stop.
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Dr. Allyson Sgro @allysonsgro.bsky.social · 21/08/2025
Very excited to be co-organizing this meeting next February. Fellow collective behavior enthusiasts, this one is for you!
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Nicoletta Petridou @nicolettapetridou.bsky.social · 22/08/2025
Brand-new conference on collective behaviour! Join us to foster a community to study how interactions among the constituents trigger fascinating collective phenomena: biofilms, fish schools, tissue self-organisation, bird swarms & many more! Thanks to amazing speakers for helping us realise this!
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Alex Schier @schierlab.bsky.social · 10/08/2025
Everything (and more) you wanted to know about Nodal Signaling. A Paradigm for TGFβ Signaling in Embryonic Development | Annual Reviews - www.annualreviews.org/content/jour...
annualreviews.org
Nodal Signaling: A Paradigm for TGFβ Signaling in Embryonic Development | Annual Reviews
Nodal signaling molecules are TGFβ family ligands that arose early during bilaterian evolution and are crucial for several key steps in embryonic development. They regulate the specification of mesode...
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Mattia Serra @mattiaserra.bsky.social · 31/07/2025
We’re recruiting PhD students & postdocs excited about nonlinear dynamics and the physics of living systems. Help us spread the word!
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Nicoletta Petridou @nicolettapetridou.bsky.social · 08/08/2025
with updated link: embl.wd103.myworkdayjobs.com/en-US/EMBL/d...
embl.wd103.myworkdayjobs.com
Postdoctoral fellow
Your Group The Petridou Lab at the European Molecular Biology Laboratory (EMBL) in Heidelberg is seeking a motivated scientist with a strong interest in establishing cutting-edge research in early emb...
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Nicoletta Petridou @nicolettapetridou.bsky.social · 08/08/2025
We are searching for an enthusiastic scientist to join our team and establish annual killifish as a model system for early developmental biology and biophysics! @embl.org @embldbunit.bsky.social Apply here: embl.wd103.myworkdayjobs.com/EMBL/job/Hei... Please re-post 🙏
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Typas Lab @typaslab.bsky.social · 30/07/2025
Ready to lead pioneering research that bridges systems-level investigations of biological systems to molecular mechanism? The EMBL Molecular Systems Biology Unit in Heidelberg is hiring a Group Leader!
embl.wd103.myworkdayjobs.com
Group Leader – Molecular Systems Biology Unit
Are you ready to lead groundbreaking research in Molecular Systems Biology? Join us at EMBL! We are seeking a motivated scientist to lead an independent research group, addressing original biological ...
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Eileen Furlong @eileen-furlong.bsky.social · 30/07/2025
To all post-docs: The Genome Biology dept ‪@embl.org has an Independent faculty position. Fantastic place to set up your lab –great package: core funding, fantastic Ph.D. students, cutting edge core facilities & great colleagues. Closing date Sept 19th embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
embl.wd103.myworkdayjobs.com
Group Leader - Genome Biology Unit
Are you ready to lead groundbreaking research in Genome Biology? Join us at EMBL! We are seeking a motivated scientist to lead an independent research group addressing exciting and original biological...
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Theory of Living Matter Group @tlmcambridge.bsky.social · 08/07/2025
🚨 Join us tomorrow for this really exciting talk on the interplay between morphogen signalling and tissue organization! 🚨
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EMBL DB unit @embldbunit.bsky.social · 05/07/2025
It's Planarian Time at the DB Unit Summer School! Today's practical is being led by the Vu group @hanhtkvu.bsky.social and focuses on size-dependent physiological changes throughout the life cycle of planarian flatworms #EMBLDevBio
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EMBL DB unit @embldbunit.bsky.social · 07/07/2025
Day 6 of the DB Unit Summer School at EMBL started with an insightful lecture by Caren Norden @nordenlab.bsky.social on the impact of nuclear properties on the behaviour of Zebrafish retinal neuroepithelia. #EMBLDevBio
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EMBL DB unit @embldbunit.bsky.social · 07/07/2025
Time for a new practical at the DB unit summer school @embl.org ! This session features the sea anemone Nematostella and explores the larva-to-polyp transition driven by neuropeptide signaling. Thanks to the Ikmi group @aikmi.bsky.social 🤩 #EMBLDevBio
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EMBL DB unit @embldbunit.bsky.social · 02/07/2025
The DB Unit Summer School, "Transitions in Developing Systems," kicked off with an incredible talk by Thibaut Brunet @thibautbrunet.bsky.social from the Pasteur Institute @pasteur.fr on the fascinating transition from unicellularity to multicellularity in choanoflagellates #EMBLDevBio
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EMBL DB unit @embldbunit.bsky.social · 03/07/2025
Day 2 of the DB Unit Summer School has now finished. We had fantastic talks from Iain Cousin #collectivebehaviour and Karen Alim #physicsofbehaviour, along with an exciting practical session from the van Gestel group on aggregative development in wild-type slime mold species #EMBLdevbio
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EMBL DB unit @embldbunit.bsky.social · 02/07/2025
At the DB Unit Summer School, it's already time for Practical 1! Participants are exploring the theory of phase transitions, critical points, and bifurcations with James Briscoe @jamesbriscoe.bsky.social and Isabella Graf @isabellagraf.bsky.social and her group members @lwuerthner.bsky.social
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EMBL DB unit @embldbunit.bsky.social · 04/07/2025
Day 3 of the DB summer school "Transitions in developing systems: from theory to experiments" started with a fantastic talk by Guillaume Salbreux, from the University of Geneva, who discussed transitions in populations of coupled phase oscillators #EMBLDevBio
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EMBL DB unit @embldbunit.bsky.social · 05/07/2025
There's always more to learn at the DB unit Summer School @embl.org ! After two engaging practical sessions yesterday from the Aulehla and Petridou groups @nicolettapetridou.bsky.social , today we will be diving into data analysis #EMBLDevBio
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EMBL DB unit @embldbunit.bsky.social · 02/07/2025
Day 1 of the DB Unit Summer School: 'Transitions in Developing Systems: From Theory to Experiments'. We are delighted to welcome all participants! Stay tuned for updates. @nicolettapetridou.bsky.social @hanhtkvu.bsky.social @jordivangestel.bsky.social @jamesbriscoe.bsky.social @karenalim.bsky.social
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Flora Vincent @floravincent.bsky.social · 17/06/2025
Excited to share the lab's 1rst preprint! Rapid high-res immunofluorescence is now possible in cultured & environmental diatoms thanks to 4-fold expansion microscopy. A step-change for comparative cell biology in one of the most important phytoplankton groups on the planet 🥳 tinyurl.com/m9s5su7s 1/2
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Jean Léon Maître @maitrejl.bsky.social · 16/06/2025
📣Join us for the DEVELOPMENTAL BIOLOGY COURSE @institutcurie.bsky.social @sorbonne-universite.fr We have fantastic speakers and registration is free! training.institut-curie.org/courses/deve... @karinayaniv.bsky.social @doetschlab.bsky.social @eileen-furlong.bsky.social @jesseveenvliet.bsky.social
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